Artesunate, an anti-malarial drug, has a potential to inhibit HCV replication.

abstract：:Human parainfluenza virus type 3 (HPIV3) causes the majority of childhood viral pneumonia around the world. Fusing the viral and target cell membranes is crucial for its entry into target cells, and the fusion process requires the concerted actions of two viral glycoproteins: hemagglutinin-neuraminidase (HN) and fusio...

journal_title：Virus genes

authors： Liu Y,Chi M,Wen H,Zhao L,Song Y,Liu N,Chi L,Wang Z

更新日期：2020-02-01 00:00:00

abstract：:We amplified the capsid protein gene fragments of 30 Japanese isolates of feline calicivirus (FCV), including the C, D, and E regions, by reverse transcription-polymerase chain reaction (RT-PCR), followed by direct sequencing. Alignment of the predicted amino acid sequences, together with other published sequences fro...

journal_title：Virus genes

authors： Horimoto T,Takeda Y,Iwatsuki-Horimoto K,Sugii S,Tajima T

更新日期：2001-01-01 00:00:00

abstract：:Recent studies show that human skin at homeostasis is a complex ecosystem whose virome include circular DNA viruses, especially papillomaviruses and polyomaviruses. To determine the chicken skin virome in comparison with human skin virome, a chicken swabs pool sample from fifteen indoor healthy chickens of five geneti...

journal_title：Virus genes

authors： Denesvre C,Dumarest M,Rémy S,Gourichon D,Eloit M

更新日期：2015-10-01 00:00:00

abstract：:Canine distemper (CD) is a highly contagious, often fatal, multisystemic, and incurable disease in dogs and other carnivores, which is caused by canine distemper virus (CDV). Although vaccines have been used as the principal means of controlling the disease, CD has been reported in vaccinated animals. The hemoagglutin...

journal_title：Virus genes

authors： Li W,Li T,Liu Y,Gao Y,Yang S,Feng N,Sun H,Wang S,Wang L,Bu Z,Xia X

更新日期：2014-08-01 00:00:00

abstract：:Marek's disease (MD), a lymphoproliferative disease of chicken is caused by a highly cell-associated alpha-herpesvirus, Marek's disease virus (MDV). MDV replicates in chicken lymphocytes and establishes a latent infection within CD4(+) T cells. The expression analysis of limited viral transcripts have revealed differe...

journal_title：Virus genes

authors： Heidari M,Huebner M,Kireev D,Silva RF

更新日期：2008-04-01 00:00:00

abstract：:The first genome of a virus infecting a representative of the eubacterial genus Actinoplanes is presented. Phage phiAsp2 has a circularly permutated chromosome that consists of 58,638 bp; its G/C-bias of 70.39% resembles the hosts G + C-content (71-73% within the genus). A total of 76 open reading frames (orfs) were i...

journal_title：Virus genes

authors： Jarling M,Bartkowiak K,Pape H,Meinhardt F

更新日期：2004-08-01 00:00:00

abstract：:Macropodid herpesvirus 1 (MaHV-1) is an unclassified alphaherpesvirus linked with the fatal infections of kangaroos and other marsupials. During the characterisation of the internal repeat region of MaHV-1, an open reading frame (ORF) encoding for thymidylate synthase (TS) gene was identified and completely sequenced....

journal_title：Virus genes

authors： Guliani S,Polkinghorne I,Smith GA,Young P,Mattick JS,Mahony TJ

更新日期：2002-06-01 00:00:00

abstract：:The search for retroviruses in human cancer cells has advanced with the discoveries of the retroviral reverse transcriptase, DNA hybridization and sequencing techniques, and polymerase chain reaction (PCR) technology. Each technological advancement has led to a better refinement and a better understanding of latent en...

journal_title：Virus genes

authors： Becker Y

更新日期：1995-02-01 00:00:00

abstract：:Nine avian influenza viruses (AIV), H5N1 subtype, were isolated from dead poultry in the Karachi region of Pakistan from 2006 to 2008. The intravenous pathogenicity indices and HA protein cleavage sites of all nine viruses were consistent with highly pathogenic AIV. Based on phylogenetic analysis of the HA genes, thes...

journal_title：Virus genes

authors： Wasilenko JL,Pantin-Jackwood M,Khan TA,Ahmed A,Rehmani SF,Lone NA,Swayne DE,Spackman E

更新日期：2012-04-01 00:00:00

abstract：:Mokola virus, one of the six genotypes within the Lyssavirus genus of the Rhabdoviridae family, is believed to be exclusive to the African continent, where infections in various mammal species have been reported. After an isolation of Mokola virus at Umhlanga on the east coast of South Africa in 1970, the virus was no...

journal_title：Virus genes

authors： Nel L,Jacobs J,Jaftha J,von Teichman B,Bingham J,Olivier M

更新日期：2000-01-01 00:00:00

abstract：:Two or three regions containing three or more successive newly defined heptads of a-d hydrophobic amino acid repeats have been located in the cDNA-derived amino acid sequences of glycoprotein G of all rhabdoviruses examined (rabies, vesicular stomatitis, fish, and plant rhabdoviruses) by computer search. These new hep...

journal_title：Virus genes

authors： Coll JM

更新日期：1995-01-01 00:00:00

abstract：:Hantaan (HTN) virus, the etiologic agent of clinically severe hemorrhagic fever with renal syndrome (HFRS), was first isolated in 1976 from lung tissues of striped field mice (Apodemus agrarius) captured in Songnae-ri, Kyungki-do, Korea. To clarify the genetic diversity and phylogenetic relationship among Korean strai...

journal_title：Virus genes

authors： Song JW,Baek LJ,Kim SH,Kho EY,Kim JH,Yanagihara R,Song KJ

更新日期：2000-10-01 00:00:00

abstract：:Gallid herpesvirus-1 (GaHV-1), commonly named infectious laryngotracheitis (ILT) virus, causes the respiratory disease in chickens known as ILT. The molecular determinants associated with differences in pathogenicity of GaHV-1 strains are not completely understood, and a comparison of genomic sequences of isolates tha...

journal_title：Virus genes

authors： Spatz SJ,Volkening JD,Keeler CL,Kutish GF,Riblet SM,Boettger CM,Clark KF,Zsak L,Afonso CL,Mundt ES,Rock DL,Garcia M

更新日期：2012-04-01 00:00:00

abstract：:Bats are carriers of potentially zoonotic viruses, therefore it is crucial to identify viruses currently found in bats to better understand how they are maintained in bat populations and evaluate risks for transmission to other species. Adenoviruses have been previously detected in bats throughout the world, but sampl...

journal_title：Virus genes

authors： Lee DN,Angiel M

更新日期：2020-02-01 00:00:00

abstract：:The VP2 gene DNA (1.4 kb in approximate) of a very virulent infectious bursal disease virus (vvIBDV) Chinju strain detected in Chinju, Korea was cloned into the bacmid, a baculovirus shuttle vector, through transposition of the gene from initially cloned pFastBacHTa plasmid, a baculovirus expression vector, and was su...

journal_title：Virus genes

authors： Kim TK,Yeo SG

更新日期：2003-08-01 00:00:00

abstract：:The NS3 protein of rice stripe virus (RSV), encoded by the virion strand of RNA3, is a viral suppressor of RNA silencing (VSR). Rice expressing NS3 had a normal phenotype, was initially sensitive to RSV but recovered at the later stages of infection. RSV accumulated slightly more in transgenic than in wild-type plants...

journal_title：Virus genes

authors： Wu G,Wang J,Yang Y,Dong B,Wang Y,Sun G,Yan C,Yan F,Chen J

更新日期：2014-06-01 00:00:00

abstract：:The intraspecies variability of capsid proteins of five viruses of the genus Comovirus was established. Inclusion of both capsid proteins to the sequence analysis reduces some uncertainties about species/strains demarcation criteria in the Comovirus genus. New approach is proposed for discrimination of Turnip ringspot...

journal_title：Virus genes

authors： Petrzik K,Koloniuk I

更新日期：2010-04-01 00:00:00

abstract：:Viral RNA from purified preparations of bean mild mosaic virus (BMMV) was resolved into two RNAs of mol. wt 1.5 X 10(6) daltons (R1) and 0.76 X 10(6) daltons (R2). Complementary DNA hybridizations, infectivity tests, and in-vitro translation studies established that R2 is a subgenomic RNA derived from R1. In-vitro tra...

journal_title：Virus genes

authors： Hari V,Gadh IP,Baunoch D,Das P

更新日期：1989-05-01 00:00:00

abstract：:The spontaneous host-range mutants 812F1 and K1/420 are derived from polyvalent phage 812 that is almost identical to phage K, belonging to family Myoviridae and genus Kayvirus. Phage K1/420 is used for the phage therapy of staphylococcal infections. Endolysin of these mutants designated LysF1, consisting of an N-term...

journal_title：Virus genes

authors： Benešík M,Nováček J,Janda L,Dopitová R,Pernisová M,Melková K,Tišáková L,Doškař J,Žídek L,Hejátko J,Pantůček R

更新日期：2018-02-01 00:00:00

abstract：:Yellow oat-grass plants (Trisetum flavescens L.) with mild mosaic and pronounced dwarfing symptoms were observed at different locations in the Czech Republic. Electron microscope observations of symptomatic plants revealed the presence of filamentous particles and inclusion bodies characteristic of the family Potyviri...

journal_title：Virus genes

authors： Hassan M,Sirlova L,Jokes M,Vacke J

更新日期：2009-08-01 00:00:00

abstract：:We have examined sequence variability among nine isolates of hop stunt viroid (HSVd) collected from hop gardens in Tohoku district in Japan, the only area in the world where hop stunt disease is endemic. Six different consensus and one-consensus sequences as well as 12 sequence variants were detected in the nine HSVd-...

journal_title：Virus genes

authors： Sano T,Mimura R,Ohshima K

更新日期：2001-01-01 00:00:00

abstract：:Recently, NADC30-like porcine reproductive and respiratory syndrome viruses (PRRSVs), which are genetically similar to the NADC30 strain isolated in the United States of America in 2008, have become prevalent in China. Here, a novel variant PRRSV strain named HNhx was successfully isolated on porcine alveolar macropha...

journal_title：Virus genes

authors： Wang LJ,Wan B,Guo Z,Qiao S,Li R,Xie S,Chen XX,Zhang G

更新日期：2018-02-01 00:00:00

abstract：:Geminiviridae consists of a large group of single-stranded DNA viruses that cause tremendous losses worldwide. Frequent mixed infection and high rates of recombination and mutation allow them to adapt rapidly to new hosts and overcome hosts' resistances. Therefore, an effective strategy able to confer plants with resi...

journal_title：Virus genes

authors： Chen W,Qian Y,Wu X,Sun Y,Wu X,Cheng X

更新日期：2014-06-01 00:00:00

abstract：:The emerging occurrence of antibiotic-resistant bacterial pathogens leads to a recollection of bacteriophage as antimicrobial therapeutics. This article presents a short overview of the clinical phage application including their use in military medicine and discusses the genotypic and phenotypic properties of a potent...

journal_title：Virus genes

authors： Reuter M,Kruger DH

更新日期：2020-04-01 00:00:00

abstract：:The infection of humans with Boma disease virus (BDV) is still a matter of debate. In a recent publication, we described a BDV (RW98) isolated from the blood of a psychiatric patient. The RNA of this virus differed more than 5% from that of the widely used strain He/80, which was supposed to represent our laboratory v...

journal_title：Virus genes

authors： Planz O,Rziha HJ,Stitz L

更新日期：2003-01-01 00:00:00

abstract：:Porcine circovirus 2 (PCV2) can cause porcine circovirus diseases and porcine circovirus-associated diseases (PCVD/PCVAD), which are widely presented in swine-producing countries. Since the discovery of this virus, considerable efforts have been devoted to understanding this pathogen and its interactions with its host...

journal_title：Virus genes

authors： Ren L,Chen X,Ouyang H

更新日期：2016-08-01 00:00:00

abstract：:The genomes (188 kbp) of the prototype Molluscum contagiosum virus type 1 (MCV-1) and a variant strain (MCV-1v) were characterized by construction of the physical maps of the viral DNA for the restriction enzymes BamHI, ClaI, EcoRI, and HindIII using a defined gene library harboring the DNA sequences of the MCV-1 geno...

journal_title：Virus genes

authors： Bugert J,Rösen-Wolff A,Darai G

更新日期：1989-11-01 00:00:00

abstract：:Complementary DNAs (cDNAs) to the RNA genome of a necrotic strain of potato virus Y in Japan (Hokkaido Univ. isolate of PVY-T:PVY-TH) were synthesized and cloned into a plasmid pBR322. About 4.3 kbp of the cDNA sequence containing the 3'-poly(A) tract of PVY-TH was inserted into a recombinant plasmid pBRYT88. The coat...

journal_title：Virus genes

authors： Hataya T,Sano T,Ohshima K,Shikata E

更新日期：1990-12-01 00:00:00

abstract：:Schmallenberg virus (SBV) is the member of Peribunyaviridae family, which comprises pathogens of importance for human and veterinary medicine. The virus is transmitted only between animals and mainly by biting midges of the genus Culicoides. This study was performed in order to determine SBV genetic diversity and eluc...

journal_title：Virus genes

authors： Kęsik-Maliszewska J,Antos A,Rola J,Larska M

更新日期：2018-12-01 00:00:00

abstract：:The sequence of rice hoja blanca tenuivirus RNA-2 is analysed and compared to its counter-part in rice stripe tenuivirus. The RNA encodes two proteins, in an ambisense arrangement. The 94 kD pc2, located in the complementary sense RNA, has several features typical of viral membrane (glyco)proteins, and also has region...

journal_title：Virus genes

authors： De Miranda JR,Muñoz M,Wu R,Hull R,Espinoza AM

更新日期：1996-01-01 00:00:00