当前位置： SCI文献检索 > VIROLOGY期刊下所有文献 > Small RNA populations for two unrelated viruses exhibit different biases in strand polarity and proximity to terminal sequences in the insect host Homalodisca vitripennis.

Small RNA populations for two unrelated viruses exhibit different biases in strand polarity and proximity to terminal sequences in the insect host Homalodisca vitripennis.

Abstract：

:Next generation sequence analyses were used to assess virus-derived small RNA (vsRNA) profiles for Homalodisca coagulata virus-1 (HoCV-1), family Dicistroviridae, and Homalodisca vitripennis reovirus (HoVRV), family Reoviridae, from virus-infected H. vitripennis, the glassy-winged sharpshooter. The vsRNA reads were mapped against the monopartite genome of HoCV-1 and all 12 genome segments of HoVRV, and 21nt vsRNAs were most common. However, strikingly contrasting patterns for the HoCV-1 and HoVRV genomic RNAs were observed. The majority of HoCV-1 vsRNAs mapped to the genomic positive-strand RNA and, although minor hotspots were observed, vsRNAs mapped across the entire genomic RNA. In contrast, HoVRV vsRNAs mapped to both positive and negative-sense strands for all genome segments, but different genomic segments showed distinct hotspots. The HoVRV vsRNAs were more common for 5' and 3' regions of HoVRV regions of all segments. These data suggest that taxonomically different viruses in the same host offer different targets for RNA-antiviral defense.

journal_name

Virology

journal_title

Virology

authors

Nandety RS,Fofanov VY,Koshinsky H,Stenger DC,Falk BW

doi

10.1016/j.virol.2013.04.005

subject

Has Abstract

pub_date

2013-07-20 00:00:00

pages

12-9

issue

1

eissn

0042-6822

issn

1096-0341

pii

S0042-6822(13)00199-2

journal_volume

442

pub_type

杂志文章

相关文献

VIROLOGY文献大全
  • A fused gene of nucleoprotein (NP) and herpes simplex virus genes (VP22) induces highly protective immunity against different subtypes of influenza virus.

    abstract：:We evaluated the immunogenicity and protective activity of plasmid DNA vaccines encoding the influenza virus NP gene (pNP) alone or in combination with the herpes simplex virus type 1 protein 22 gene (pVP22). Optimal immune responses were observed in BALB/c mice immunized with the combination of pVP22 plus pNP, as ass...

    journal_title：Virology

    pub_type： 杂志文章

    doi：10.1016/j.virol.2006.04.015

    authors： Saha S,Yoshida S,Ohba K,Matsui K,Matsuda T,Takeshita F,Umeda K,Tamura Y,Okuda K,Klinman D,Xin KQ,Okuda K

    更新日期：2006-10-10 00:00:00

  • Small RNA-based interactions between rice and the viruses which cause the tungro disease.

    abstract：:Rice tungro disease is caused by a complex of two viruses, Rice tungro bacilliform virus (RTBV) and Rice tungro spherical virus (RTSV). To examine the RNAi-based defence response in rice during tungro disease, we characterized the virus-derived small RNAs and miRNAs by Deep Sequencing. We found that, while 21 nt/22 nt...

    journal_title：Virology

    pub_type： 杂志文章

    doi：10.1016/j.virol.2018.07.022

    authors： Zarreen F,Kumar G,Johnson AMA,Dasgupta I

    更新日期：2018-10-01 00:00:00

  • Relative replication fitness of efavirenz-resistant mutants of HIV-1: correlation with frequency during clinical therapy and evidence of compensation for the reduced fitness of K103N + L100I by the nucleoside resistance mutation L74V.

    abstract：:Efavirenz resistance during HIV-1 treatment failure is usually associated with the reverse transcriptase mutation K103N. L100I, V108I, or P225H can emerge after K103N and increase its level of efavirenz resistance. K103N + L100I is the most drug-resistant of the double mutants but is the least common clinically. We hy...

    journal_title：Virology

    pub_type： 杂志文章

    doi：10.1016/j.virol.2006.05.021

    authors： Koval CE,Dykes C,Wang J,Demeter LM

    更新日期：2006-09-15 00:00:00

  • Analysis of human immunodeficiency virus type 1 promoter insertion in vivo.

    abstract：:Our study reports the occurrence of HIV-1 insertional activation events in vivo. Using a previously described PCR assay, small aliquots of broncho-alveolar lavage (BAL) cells obtained from AIDS patients were analyzed. Nine percent (5/54) of the aliquots contained proviral-host sequence transcripts indicating HIV-1 pro...

    journal_title：Virology

    pub_type： 杂志文章

    doi：10.1006/viro.1995.1161

    authors： Raineri I,Solèr M,Senn HP

    更新日期：1995-04-01 00:00:00

  • Cellular minichromosome maintenance complex component 5 (MCM5) is incorporated into HIV-1 virions and modulates viral replication in the newly infected cells.

    abstract：:The post-entry events of HIV-1 infection occur within reverse transcription complexes derived from the viral cores entering the target cell. HIV-1 cores contain host proteins incorporated from virus-producing cells. In this report, we show that MCM5, a subunit of the hexameric minichromosome maintenance (MCM) DNA heli...

    journal_title：Virology

    pub_type： 杂志文章

    doi：10.1016/j.virol.2016.06.023

    authors： Santos S,Obukhov Y,Nekhai S,Pushkarsky T,Brichacek B,Bukrinsky M,Iordanskiy S

    更新日期：2016-10-01 00:00:00

  • Sequence diversity of the capsid gene and the nonstructural gene NS2B of dengue-3 virus in vivo.

    abstract：:Previously, we studied the envelope (E) gene of dengue virus and reported that dengue-3 virus is present as a quasispecies. To investigate the extent of intrahost sequence variation of other dengue viral genes, we examined in this study the capsid (C) gene and the nonstructural gene, NS2B, derived directly from plasma...

    journal_title：Virology

    pub_type： 杂志文章

    doi：10.1006/viro.2002.1635

    authors： Wang WK,Sung TL,Lee CN,Lin TY,King CC

    更新日期：2002-11-10 00:00:00

  • Identification of proteins encoded by avian reoviruses and evidence for post-translational modification.

    abstract：:Twelve avian reovirus strain 176 proteins, 10 structural (lambda 1, lambda 2, lambda 3, mu 1, mu 2/mu 2C, sigma 1, sigma 2, sigma 3, and sigma 4), and 2 nonstructural (mu NS and sigma NS) were identified and characterized by electrophoretic analysis of purified virions and infected cell lysates. Three of the identifie...

    journal_title：Virology

    pub_type： 杂志文章

    doi：10.1006/viro.1993.1147

    authors： Ni Y,Ramig RF,Kemp MC

    更新日期：1993-03-01 00:00:00

  • Epidermal growth factor receptor is a co-factor for transmissible gastroenteritis virus entry.

    abstract：:Transmissible gastroenteritis virus (TGEV) causes severe diarrhea and high mortality in newborn piglets. It is well established that porcine intestinal epithelium is the target of the TGEV infection, however the mechanism that TGEV invades the host epithelium remains largely unknown. Aminopeptidase N (APN) is a known ...

    journal_title：Virology

    pub_type： 杂志文章

    doi：10.1016/j.virol.2018.05.009

    authors： Hu W,Zhang S,Shen Y,Yang Q

    更新日期：2018-08-01 00:00:00

  • Identification of RNA ligands that bind hepatitis C virus polymerase selectively and inhibit its RNA synthesis from the natural viral RNA templates.

    abstract：:To identify the potential RNA inhibitors of HCV polymerase, we have isolated high-affinity RNA ligands specific to hepatitis C virus (HCV) NS5B protein from a combinatorial RNA library using the Systematic Evolution of Ligands by EXponential enrichment (SELEX) procedure. Thirty-seven selected ligands were classified i...

    journal_title：Virology

    pub_type： 杂志文章

    doi：10.1016/s0042-6822(02)00095-8

    authors： Vo NV,Oh JW,Lai MM

    更新日期：2003-03-15 00:00:00

  • Genetic characterization of an adapted pandemic 2009 H1N1 influenza virus that reveals improved replication rates in human lung epithelial cells.

    abstract：:The 2009 influenza pandemic originated from a swine-origin H1N1 virus, which, although less pathogenic than anticipated, may acquire additional virulence-associated mutations in the future. To estimate the potential risk, we sequentially passaged the isolate A/Hamburg/04/2009 in A549 human lung epithelial cells. After...

    journal_title：Virology

    pub_type： 杂志文章

    doi：10.1016/j.virol.2016.02.002

    authors： Wörmann X,Lesch M,Welke RW,Okonechnikov K,Abdurishid M,Sieben C,Geissner A,Brinkmann V,Kastner M,Karner A,Zhu R,Hinterdorfer P,Anish C,Seeberger PH,Herrmann A,Meyer TF,Karlas A

    更新日期：2016-05-01 00:00:00

  • Influence of CCR7 ligand DNA preexposure on the magnitude and duration of immunity.

    abstract：:The CC chemokine receptor (CCR) 7 ligands CCL21 and CCL19 were recently described as essential elements for establishing the microenvironment needed to initiate optimal immune responses in secondary lymphoid tissues. In the present study we have kinetically investigated the primary responses of naive DO11.10 TCR-trans...

    journal_title：Virology

    pub_type： 杂志文章

    doi：10.1016/s0042-6822(03)00199-5

    authors： Lee Y,Eo SK,Rouse RJ,Rouse BT

    更新日期：2003-07-20 00:00:00

  • The effect of inhibitors on the growth of the entomopoxvirus from Amsacta moorei in Lymantria dispar (gypsy moth) cells.

    abstract：:Within the family of Poxviridae, the entomopoxviruses are the most distant relatives of the more well-known and intensively studied orthopoxviruses (vaccinia and variola). The growth of the entomopoxvirus from Amsacta moorei (AmEPV) has been characterized in cell culture and compared to that of vaccinia virus (VV), th...

    journal_title：Virology

    pub_type： 杂志文章

    doi：10.1006/viro.1995.1428

    authors： Winter J,Hall RL,Moyer RW

    更新日期：1995-08-20 00:00:00

  • Genetic analysis of bipartite geminivirus tissue tropism.

    abstract：:The bipartite geminiviruses bean golden mosaic virus (BGMV), cabbage leaf curl virus (CabLCV), and tomato golden mosaic virus (TGMV) exhibit differential tissue tropism in Nicotiana benthamiana. In systemically infected leaves, BGMV remains largely confined to vascular-associated cells (phloem-limited), whereas CabLCV...

    journal_title：Virology

    pub_type： 杂志文章

    doi：10.1006/viro.2001.1205

    authors： Qin Y,Petty IT

    更新日期：2001-12-20 00:00:00

  • Conserved aromatic residues of the hepatitis B virus Precore propeptide are involved in a switch between distinct dimeric conformations and essential in the formation of heterocapsids.

    abstract：:The Hepatitis B virus Precore protein, present in the secretory pathway as the HBeAg precursor, can associate in the cytoplasm with the Core protein to form heterocapsids, likely to favor viral persistence. Core and Precore proteins share their primary sequence except for ten additional aminoacids at the N-terminus of...

    journal_title：Virology

    pub_type： 杂志文章

    doi：10.1016/j.virol.2014.06.013

    authors： Duriez M,Thouard A,Bressanelli S,Rossignol JM,Sitterlin D

    更新日期：2014-08-01 00:00:00

  • Cell surface binding simian virus 40 large T antigen becomes anchored and stably linked to lipid of the target cells.

    abstract：:Previously a new small subclass of SV40 large T antigen with a high-binding affinity to living target cells was characterized (J. Lange-Mutschler and R. Henning, 1983, Virology 127, 333-344.) In the present study the external binding process, particularly the tight linkage of T antigen to lipid of the target cells, wa...

    journal_title：Virology

    pub_type： 杂志文章

    doi：10.1016/0042-6822(84)90176-4

    authors： Lange-Mutschler J,Henning R

    更新日期：1984-07-30 00:00:00

  • HIV-1 integration is inhibited by stimulation of the VPAC2 neuroendocrine receptor.

    abstract：:Successful HIV-1 infection requires a number of specific stages leading to integration of the provirus. We previously suggested that members of the VPAC neuroendocrine receptor family may play a role in HIV-1 infection. We now show that stimulation of the VPAC2 receptor with specific agonists provides strong resistanc...

    journal_title：Virology

    pub_type： 杂志文章

    doi：10.1016/j.virol.2006.12.012

    authors： Bokaei PB,Ma XZ,Sakac D,Branch DR

    更新日期：2007-05-25 00:00:00

  • The roles of the red clover necrotic mosaic virus capsid and cell-to-cell movement proteins in systemic infection.

    abstract：:The red clover necrotic mosaic dianthovirus (RCNMV) genome is split between two single-stranded RNA species termed RNA-1 and RNA-2. RNA-2 is required for infection of whole plants but is dispensable for infection and virion formation in protoplasts. We have used full-length cDNA clones of RNA-1 and -2 from which infec...

    journal_title：Virology

    pub_type： 杂志文章

    doi：10.1006/viro.1993.1004

    authors： Xiong Z,Kim KH,Giesman-Cookmeyer D,Lommel SA

    更新日期：1993-01-01 00:00:00

  • The structure and cloning of orf virus DNA.

    abstract：:A map of cleavage sites for the restriction endonucleases EcoRI, HindIII, BamHI, HpaI, and KpnI for a New Zealand strain of orf virus (NZ2) DNA has been deduced. Also, the entire genome, apart from approximately 0.1 kbp at each end, has been cloned into various vectors. The genome is 139 kbp in length and, in common w...

    journal_title：Virology

    pub_type： 杂志文章

    doi：10.1016/0042-6822(87)90307-2

    authors： Mercer AA,Fraser K,Barns G,Robinson AJ

    更新日期：1987-03-01 00:00:00

  • Porcine endogenous retroviruses inhibit human immune cell function: risk for xenotransplantation?

    abstract：:Transgenic pigs are currently the most favored potential source of organs for xenotransplantation. Like all mammalian species they all harbor endogenous retroviruses in their genome. These porcine endogenous retroviruses (PERVs) are produced from several primary cells and cell lines and are able to infect human cells....

    journal_title：Virology

    pub_type： 杂志文章

    doi：10.1006/viro.1999.0149

    authors： Tacke SJ,Kurth R,Denner J

    更新日期：2000-03-01 00:00:00

  • Identification of novel virus-specific antigens by CD4⁺ and CD8⁺ T cells from asymptomatic HSV-2 seropositive and seronegative donors.

    abstract：:Reactivation of latent herpes simplex virus 2 (HSV-2) infections can be characterized by episodic recurrent genital lesions and/or viral shedding. We hypothesize that infected (HSV-2(pos)) asymptomatic individuals have acquired T cell responses to specific HSV-2 antigen(s) that may be an important factor in controllin...

    journal_title：Virology

    pub_type： 杂志文章

    doi：10.1016/j.virol.2014.07.018

    authors： Long D,Skoberne M,Gierahn TM,Larson S,Price JA,Clemens V,Baccari AE,Cohane KP,Garvie D,Siber GR,Flechtner JB

    更新日期：2014-09-01 00:00:00

  • Biochemical analysis of the capsid protein gene and capsid protein of tobacco etch virus: N-terminal amino acids are located on the virion's surface.

    abstract：:The sequence of the 1491 nucleotides found at the 3' end of the genome of the highly aphid-transmissible (HAT) isolate of tobacco etch virus (TEV) has been determined. The nucleotide sequence of the capsid protein gene has been identified and compared with the corresponding region of the not-aphid-transmissible (NAT) ...

    journal_title：Virology

    pub_type： 杂志文章

    doi：10.1016/0042-6822(85)90133-3

    authors： Allison RF,Dougherty WG,Parks TD,Willis L,Johnston RE,Kelly M,Armstrong FB

    更新日期：1985-12-01 00:00:00

  • Loss of the N-linked glycosylation site at position 386 in the HIV envelope V4 region enhances macrophage tropism and is associated with dementia.

    abstract：:HIV infects macrophages and microglia in the central nervous system (CNS). Mechanisms that enhance HIV macrophage/microglial tropism are not well understood. Here, we identify an HIV Env variant in the V4 region of gp120, Asp 386 (D386), that eliminates an N-linked glycosylation site at position 386, enhances viral re...

    journal_title：Virology

    pub_type： 杂志文章

    doi：10.1016/j.virol.2007.05.029

    authors： Dunfee RL,Thomas ER,Wang J,Kunstman K,Wolinsky SM,Gabuzda D

    更新日期：2007-10-10 00:00:00

  • Computational analysis of four human adenovirus type 4 genomes reveals molecular evolution through two interspecies recombination events.

    abstract：:Computational analysis of human adenovirus type 4 (HAdV-E4), a pathogen that is the only HAdV member of species E, provides insights into its zoonotic origin and molecular adaptation. Its genome encodes a domain of the major capsid protein, hexon, from HAdV-B16 recombined into the genome chassis of a simian adenovirus...

    journal_title：Virology

    pub_type： 杂志文章

    doi：10.1016/j.virol.2013.05.014

    authors： Dehghan S,Seto J,Liu EB,Walsh MP,Dyer DW,Chodosh J,Seto D

    更新日期：2013-09-01 00:00:00

  • Select resistance-associated mutations in blood are associated with lower CSF viral loads and better neuropsychological performance.

    abstract：BACKGROUND:When antiretroviral therapy does not fully suppress HIV replication, suboptimal levels of antiretrovirals can select for antiretroviral resistant variants of HIV. These variants may exhibit reduced replication capacity and result in lower viral loads in blood. Our study evaluated whether antiretroviral resis...

    journal_title：Virology

    pub_type： 杂志文章

    doi：10.1016/j.virol.2009.08.007

    authors： Hightower GK,Letendre SL,Cherner M,Gibson SA,Ellis RJ,Wolfson TJ,Gamst AC,Ignacio CC,Heaton RK,Grant I,Richman DD,Smith DM,HNRC Group.

    更新日期：2009-11-25 00:00:00

  • Identification of constrained peptides that bind to and preferentially inhibit the activity of the hepatitis C viral RNA-dependent RNA polymerase.

    abstract：:A class of disulfide constrained peptides containing a core motif FPWG was identified from a screen of phage displayed library using the HCV RNA-dependent RNA polymerase (NS5B) as a bait. Surface plasmon resonance studies showed that three highly purified synthetic constrained peptides bound to immobilized NS5B with e...

    journal_title：Virology

    pub_type： 杂志文章

    doi：10.1016/s0042-6822(03)00313-1

    authors： Amin A,Zaccardi J,Mullen S,Olland S,Orlowski M,Feld B,Labonte P,Mak P

    更新日期：2003-08-15 00:00:00

  • Comparison of the antiviral activity of the microbicide candidate griffithsin and its tandemers derivatives against different modes of HIV-1 transmission.

    abstract：:Tandemers 2MG, 2MG3, 3MG and 4MG are derivatives of the potent anti-HIV-1 microbicide candidate griffithsin (GRFT). We compared these compounds anti-HIV-1 activity to GRFT using the viruses CAP206.08 and CAAN5342.A2 that have decreased sensitivity to this lectin. The 2MG and 2MG3 tandemers had similar activity to GRFT...

    journal_title：Virology

    pub_type： 杂志文章

    doi：10.1016/j.virol.2020.01.017

    authors： Alexandre K,Malatji K,Mulaudzi T

    更新日期：2020-05-01 00:00:00

  • A convenient in vivo cap donor delivery system to investigate the cap snatching of plant bunyaviruses.

    abstract：:Like their animal-infecting counterparts, plant bunyaviruses use capped RNA leaders cleaved from host cellular mRNAs to prime viral genome transcription in a process called cap-snatching, but in vivo systems to investigate the details of this process are lacking for them. Here, we report that Rice stripe tenuivirus (R...

    journal_title：Virology

    pub_type： 杂志文章

    doi：10.1016/j.virol.2019.10.017

    authors： Lin W,Wu R,Qiu P,Jing Jin,Yang Y,Wang J,Lin Z,Zhang J,Wu Z,Du Z

    更新日期：2020-01-02 00:00:00

  • Properties of a new virus belonging to nodaviridae found in larval striped jack (Pseudocaranx dentex) with nervous necrosis.

    abstract：:Spherical virus particles were purified from larval striped jack (Pseudocaranx dentex) with nervous necrosis. The virus consists of nonenveloped particles, about 25 nm in diameter, and contains two single-stranded, positive-sense RNA molecules with molecular weights of 1.01 x 10(6)Da (RNA 1) and 0.49 x 10(6)Da (RNA 2)...

    journal_title：Virology

    pub_type： 杂志文章

    doi：10.1016/0042-6822(92)90329-n

    authors： Mori K,Nakai T,Muroga K,Arimoto M,Mushiake K,Furusawa I

    更新日期：1992-03-01 00:00:00

  • The cytoplasmic tail of Herpes simplex virus glycoprotein H binds to the tegument protein VP16 in vitro and in vivo.

    abstract：:During Herpes simplex virus envelopment, capsids, tegument polypeptides, and membrane proteins assemble at the site of budding and a cellular lipid bilayer becomes refashioned into a spherical envelope. Though the molecular interactions driving these events are poorly understood, several lines of evidence suggest that...

    journal_title：Virology

    pub_type： 杂志文章

    doi：10.1016/j.virol.2003.08.023

    authors： Gross ST,Harley CA,Wilson DW

    更新日期：2003-12-05 00:00:00

  • Monoclonal antibodies raised to purified woodchuck hepatitis virus core antigen particles demonstrate X antigen reactivity.

    abstract：:Woodchuck hepatitis core antigen (WHcAg) particles purified from the liver of chronically infected animals were used for monoclonal antibody production. Most of the putative clones demonstrated anti-WHc specificity. However, the supernatants from several putative clones bound X antigen sequences from woodchuck hepatit...

    journal_title：Virology

    pub_type： 杂志文章

    doi：10.1016/0042-6822(90)90491-9

    authors： Feitelson MA,Clayton MM,Phimister B

    更新日期：1990-07-01 00:00:00