Assessment of the Relationship between Carotid Intima-Media Thickening and Early-Stage Diabetic Kidney Disease Coupled with Helicobacter pylori Infection.

abstract：:Epithelial cancers, including those of the skin and cervix, are the most common type of cancers in humans. Many recent studies have attempted to use Raman spectroscopy to diagnose these cancers. In this paper, Raman spectral markers related to the temporal and spatial effects of cervical and skin cancers are examined ...

journal_title：Disease markers

authors： Keller MD,Kanter EM,Lieber CA,Majumder SK,Hutchings J,Ellis DL,Beaven RB,Stone N,Mahadevan-Jansen A

更新日期：2008-01-01 00:00:00

abstract：:There is increasing evidence to support the use of CA125 in the follow-up and management of patients with ovarian cancer and several commercial kits are now available for its measurement. This study investigated and compared the performance of three of them: an enzyme immunoassay (EIA) and an immunoradiometric assay (...

journal_title：Disease markers

authors： Fisken J,Leonard RC,Roulston JE

更新日期：1989-01-01 00:00:00

abstract：Background:Syndecan-1 (SDC1/CD138) is a key cell surface adhesion molecule essential for maintaining cell morphology and the interactions with the surrounding microenvironment. SDC1 tumor immunoexpression may be increased or decreased in epithelial malignant neoplasms compared to that in adjacent non-neoplastic tissue,...

journal_title：Disease markers

authors： Li K,Li L,Wu X,Yu J,Ma H,Zhang R,Li Y,Wang W

更新日期：2019-04-30 00:00:00

abstract：:Respiratory syncytial virus (RSV) is the most common viral respiratory pathogen during infancy world wide. It induces innate and adaptive immune response in host cells. The toll like receptor 4 (TLR4)/CD14 complex is particularly important for the initiation of an innate immune response to RSV. Thus we were interested...

journal_title：Disease markers

authors： Puthothu B,Forster J,Heinzmann A,Krueger M

更新日期：2006-01-01 00:00:00

abstract：Backgrounds:Both pretreatment serum CRP (C-reactive protein) level and ALB (albumin) level have been found to be predictive of survival for multiple malignancies including sarcoma. Since both of the GPS (Glasgow prognostic score) and CAR (C-reactive protein to albumin ratio) are based on the combination of CRP and ALB,...

journal_title：Disease markers

authors： Fang E,Wang X,Feng J,Zhao X

更新日期：2020-01-07 00:00:00

abstract：:Clinical variables contribute to the severity of Kashin-Beck disease (KBD). However, it is unclear if there is a correlation between gene expression and clinical variables. Peripheral blood samples were collected from 100 patients with KBD and 100 healthy controls from KBD-endemic areas to identify differentially expr...

journal_title：Disease markers

authors： Wang X,Ning Y,Zhang P,Yang L,Li C,Zhou R,Guo X

更新日期：2019-01-03 00:00:00

abstract：BACKGROUND:Echocardiographic evaluation of left ventricular (LV) structural and functional alterations in hypertension has some limitations, potentially overcome by using biomarkers. ST2, a prognostic biomarker for heart failure and myocardial infarction patients, was less studied in hypertension. AIM:To analyze the r...

journal_title：Disease markers

authors： Farcaş AD,Anton FP,Goidescu CM,Gavrilă IL,Vida-Simiti LA,Stoia MA

更新日期：2017-01-01 00:00:00

abstract：:Involvement of the ets-1 proto-oncogene located at chromosome band 11q23 was studied in six tumors and in a congenital chromosome abnormality affecting the 11q23 region, in order to determine whether the breakpoint of these rearrangements was identical at the molecular level. In multiple restriction digestions a 5.4 k...

journal_title：Disease markers

authors： Koduru PR,Offit K,Jhanwar SC

更新日期：1989-07-01 00:00:00

abstract：BACKGROUND:We investigated the relationship between NT-pro-BNP, glomerular filtration rate (GFR), and all-cause mortality rates in a cohort of older people discharged from an internal medicine unit after admission for dyspnoea. PATIENTS AND METHODS:NT-pro-BNP was evaluated in serum samples of 134 patients aged 80 ± 6 ...

journal_title：Disease markers

authors： Fabbian F,De Giorgi A,Pala M,Volpato S,Portaluppi F,Zuliani G,Manfredini R

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Stroke subtype diagnosis leads to specific therapies to reduce recurrences. Because nearly one third of patients remain with unknown etiology after a complete screening workup, we aim to investigate whether molecular markers of myocardial damage were associated with cardioembolic stroke and if they were usef...

journal_title：Disease markers

authors： Rodríguez-Yáñez M,Sobrino T,Blanco M,de la Ossa NP,Brea D,Rodríguez-González R,Leira R,Dávalos A,Castillo J

更新日期：2009-01-01 00:00:00

abstract：OBJECTIVE:Particularly interesting new cysteine-histidine rich protein (PINCH) is an important component of the local adhesion complexes and upregulated in several types of malignancies, and involved in the incidence and development of tumours. PINCH expression is also independently correlated with poorer survival in p...

journal_title：Disease markers

authors： Zhu ZL,Yan BY,Zhang Y,Yang YH,Wang ZM,Zhang HZ,Wang MW,Zhang XH,Sun XF

更新日期：2012-01-01 00:00:00

abstract：:Decreased levels of brain-derived neurotrophic factor (BDNF) are assumed to play a crucial role in the pathophysiology of mild neurocognitive disorders (MNCDs). In this study, we compared plasma BDNF levels (at baseline and after two months of treatment with escitalopram) in patients with the main types of MNCDs and n...

journal_title：Disease markers

authors： Levada OA,Cherednichenko NV,Trailin AV,Troyan AS

更新日期：2016-01-01 00:00:00

abstract：:Cerebrospinal fluid (CSF) is the body fluid closest to the pathology of multiple sclerosis (MS). For many candidate biomarkers CSF is the only fluid that can be investigated. Several factors need to be standardized when sampling CSF for biomarker research: time/volume of CSF collection, sample processing/storage, and ...

journal_title：Disease markers

authors： Giovannoni G

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:The associations between the Fractalkine receptor (CX3CR1) gene T280M (rs3732378) and V249I (rs3732379) polymorphisms and atherosclerosis (AS) risk are conflicting. The aim of this meta-analysis was undertaken to assess their associations. METHODS:PubMed, Embase, Web of Science, Medline, Cochrane database, ...

journal_title：Disease markers

authors： Wu J,Yin RX,Lin QZ,Guo T,Shi GY,Sun JQ,Shen SW,Li Q

更新日期：2014-01-01 00:00:00

abstract：INTRODUCTION:Acute gangrenous appendicitis (AGA) is a common medical condition; however, the grade of appendicitis usually cannot be established preoperatively. We have attempted to identify some indicators, such as the mean platelet volume (MPV) and the platelet distribution width (PDW), to diagnose AGA. Aims. To eval...

journal_title：Disease markers

authors： Fan Z,Pan J,Zhang Y,Wang Z,Zhu M,Yang B,Shi L,Jing H

更新日期：2015-01-01 00:00:00

abstract：:Purpose. The aim of this study was to evaluate the sensitivity of pleural C-reactive protein (CRP) biomarker levels in identifying parapneumonic effusions. Methods. A single-center, retrospective review of 244 patients diagnosed with pleural effusions was initiated among patients at the Rabin Medical Center, Petah Tik...

journal_title：Disease markers

authors： Izhakian S,Wasser WG,Fox BD,Vainshelboim B,Kramer MR

更新日期：2016-01-01 00:00:00

abstract：:In recent researches, high expression of nesfatin-1/nucleobindin-2 (NUCB2) is linked to poor prognosis in prostate and colon cancer due to the enhancement in proliferation, migration, and invasion. However, the role of nesfatin-1 in bladder cancer is not clear. In this study, we examined the expression of NUCB2 in bla...

journal_title：Disease markers

authors： Liu GM,Xu ZQ,Ma HS

更新日期：2018-09-19 00:00:00

abstract：:Chronic infection with the hepatitis B virus (HBV) is a known risk factor in the development of human hepatocellular carcinoma (HCC). The HBV-encoded X protein, HBx, has been investigated for properties that may explain its cancer cofactor role in transgenic mouse lines. We discuss here recent data showing that HBx is...

journal_title：Disease markers

authors： Madden CR,Slagle BL

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:Some studies have suggested a relation of plasma fibrinogen to the severity of coronary artery disease (CAD). However, whether plasma fibrinogen can predict the presence and severity of CAD in patients with diabetes mellitus has not been determined. METHODS:A total of consecutive 373 diabetic patients with ...

journal_title：Disease markers

authors： Hong LF,Li XL,Luo SH,Guo YL,Zhu CG,Qing P,Wu NQ,Li JJ

更新日期：2014-01-01 00:00:00

abstract：:Nonalcoholic fatty liver disease (NAFLD) is one of the most prevalent chronic liver diseases. Obesity is the most common and well-established risk factor for NAFLD, but there are large interindividual differences in the relationship between weight status and the development of NAFLD. Beta-3-adrenergic receptor (ADRB3)...

journal_title：Disease markers

authors： Sakamoto Y,Oniki K,Kumagae N,Morita K,Otake K,Ogata Y,Saruwatari J

更新日期：2019-12-17 00:00:00

abstract：BACKGROUND:specific polymorphisms of genes regulating intracellular redox balance and oxidative stress are related to atherogenesis. Some studies have identified a relationship between progression of atherosclerosis and C242T mutation in CYBA gene coding for p22phox, a subunit of the NADH/NADPH oxidase system. DESIGN:...

journal_title：Disease markers

authors： Nasti S,Spallarossa P,Altieri P,Garibaldi S,Fabbi P,Polito L,Bacino L,Brunelli M,Brunelli C,Barsotti A,Ghigliotti G

更新日期：2006-01-01 00:00:00

abstract：INTRODUCTION:This study was designed to correlate the serum and gingival crevicular fluid (GCF) levels of progranulin (PGRN) and high sensitivity C-reactive protein (hs CRP) in chronic periodontitis and type 2 diabetes mellitus (DM). DESIGN:PGRN and hs CRP levels were estimated in 3 groups: healthy, chronic periodonti...

journal_title：Disease markers

authors： Priyanka N,Kumari M,Kalra N,Arjun P,Naik SB,Pradeep AR

更新日期：2013-01-01 00:00:00

abstract：:Nasopharyngeal carcinoma (NPC) is a head and neck cancer that is highly found in distinct geographic areas, such as Southeast Asia. The management of NPC remains burdensome as the prognosis is poor due to the late presentation of the disease and the complex nature of NPC pathogenesis. Therefore, it is necessary to fin...

journal_title：Disease markers

authors： Janvilisri T

更新日期：2015-01-01 00:00:00

abstract：:Kidney insufficiency is a hallmark of nephropathia epidemica (NE). Little is known about the mechanisms of the NE kidney pathology, with current knowledge mainly based on findings in postmortem tissue. We have analyzed kidney damage biomarkers in urine collected from early- and late-phase NE using Bio-Plex kidney toxi...

journal_title：Disease markers

authors： Martynova EV,Maksudova AN,Shakirova VG,Abdulkhakov SR,Khaertynova IM,Anokhin VA,Ivanova VV,Abiola IM,Garanina EE,Tazetdinova LG,Valiullina AH,Khaiboullina SF

更新日期：2018-02-26 00:00:00

abstract：:Background. Proper diagnosis of pancreatic lesion etiology is a challenging clinical dilemma. Studies suggest that surgery for suspected pancreatic ductal adenocarcinoma (PDAC) reveals a benign lesion in 5% to 13% of cases. The aim of our study was to assess whether routinely used biomarkers such as CA19-9, Ca125, Ca1...

journal_title：Disease markers

authors： Hogendorf P,Skulimowski A,Durczyński A,Kumor A,Poznańska G,Oleśna A,Rut J,Strzelczyk J

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Cardiac troponin levels have been reported to add value in the detection of cardiovascular complications in noncardiac surgery. A sensitive cardiac troponin I (cTnI) assay could provide more accurate prognostic information. METHODS:This study prospectively enrolled 142 patients with at least one Revised Car...

journal_title：Disease markers

authors： Borges FK,Furtado MV,Rossini AP,Bertoluci C,Gonzalez VL,Bertoldi EG,Pezzali LG,Machado DL,Grutcki DM,Rech LG,Magalhães M,Polanczyk CA

更新日期：2013-01-01 00:00:00

abstract：:Microsatellite instability (MSI) analysis is becoming more and more important to detect sporadic primary tumors of the MSI phenotype as well as in helping to determine Hereditary Non-Polyposis Colorectal Cancer (HNPCC) cases. After some years of conflicting data due to the absence of consensus markers for the MSI phen...

journal_title：Disease markers

authors： Buhard O,Suraweera N,Lectard A,Duval A,Hamelin R

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:Liver cirrhosis (LC) is the final stage of most of chronic liver diseases and is almost caused by chronic hepatitis B (CHB) in China. Liver biopsy is the reference method for the evaluation of liver cirrhosis. However, it is an invasive procedure with inherent risk. The aim of this study was to construct a n...

journal_title：Disease markers

authors： Cao Y,Hu ZD,Liu XF,Deng AM,Hu CJ

更新日期：2013-01-01 00:00:00

abstract：:In view of the potential uses of cell surface tumour associated antigens in novel anticancer treatment, a study was designed to investigate whether the biological response modifiers interferon-gamma (IFN-gamma) and tumour necrosis factor-alpha (TNF-alpha) could effect the expression of an epitope on the tumour associa...

journal_title：Disease markers

authors： Clark S,McGuckin MA,Hurst T,Ward BG

更新日期：1994-10-01 00:00:00

abstract：:The surface and cytoplasmic expression of CD1a molecules was analysed by indirect immunofluorescence (IIF) and dot blot assay (DBA) in a panel of 40 acute and chronic leukaemias. Thirty-two per cent of the samples were positive by IIF but, surprisingly, 72 per cent of the patients were positive by DBA, suggesting the ...

journal_title：Disease markers

authors： Salamone MC,Roisman FR,Morelli AE,Noli MI,Fainboim L

更新日期：1990-09-01 00:00:00