PINCH expression and its clinicopathological significance in gastric adenocarcinoma.

abstract：UNLABELLED:The aim of this study was to investigate serum IL17 levels in patients with Crohn's disease (CD) and to investigate the relationship between serum IL17 levels with disease activity. METHODS:Fifty patients with CD and sex- and age-matched 40 healthy controls were included in the study. The serum IL17 levels,...

journal_title：Disease markers

authors： Sahin A,Calhan T,Cengiz M,Kahraman R,Aydin K,Ozdil K,Korachi M,Sokmen HM

更新日期：2014-01-01 00:00:00

abstract：Background:The systemic immune-inflammation index (SII), based on peripheral lymphocytes, neutrophils, and platelet count, has been used as a prognostic marker for several tumors. However, use of the SII has not been reported for gastric cancer. Methods:We evaluated the prognostic value of the SII in primary and valid...

journal_title：Disease markers

authors： Shi H,Jiang Y,Cao H,Zhu H,Chen B,Ji W

更新日期：2018-12-02 00:00:00

abstract：Objective:To evaluate the performance of serum and urinary sCD163 concentrations as possible biomarker in systemic sclerosis (SSc). Methods:Urine and serum samples were obtained from SSc patients and age- and sex-matched controls. Serum and urinary sCD163 concentrations were measured by commercially available ELISA ki...

journal_title：Disease markers

authors： Frantz C,Pezet S,Avouac J,Allanore Y

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND:Previous studies on the role of inflammation in the pathophysiology of sickle cell disease (SCD) suggested that the CCR5Δ32 allele, which is responsible for the production of truncated C-C chemokine receptor type 5 (CCR5), could confer a selective advantage on patients with SCD because it leads to a less eff...

journal_title：Disease markers

authors： Lopes MP,Santos MN,Faber EW,Bezerra MA,Hatzlhofer BL,Albuquerque DM,Zaccariotto TR,Ribeiro DM,Araújo Ada S,Costa FF,Sonati Mde F

更新日期：2014-01-01 00:00:00

abstract：:IgA nephropathy is diagnosed by renal biopsy, an invasive procedure with a risk of significant complications. Noninvasive approaches are needed for possible diagnostic purposes and especially for monitoring disease activity or responses to treatment. In this pilot project, we assessed the utility of urine samples as s...

journal_title：Disease markers

authors： Neprasova M,Maixnerova D,Novak J,Reily C,Julian BA,Boron J,Novotny P,Suchanek M,Tesar V,Kacer P

更新日期：2016-01-01 00:00:00

abstract：AIM:To assess and compare the roles of plasma and urine concentrations of neutrophil gelatinase associated lipocalin (NGAL) and Cystatin C for early diagnosis of septic acute kidney injury (AKI) in adult critically ill patients. METHODS:Patients were divided into three groups as sepsis-non AKI, sepsis-AKI and non seps...

journal_title：Disease markers

authors： Aydoğdu M,Gürsel G,Sancak B,Yeni S,Sarı G,Taşyürek S,Türk M,Yüksel S,Senes M,Ozis TN

更新日期：2013-01-01 00:00:00

abstract：Purpose:Modern neuroimaging techniques allow investigating brain structures and substances involved in the pathophysiology of mental disorders, trying to find new markers of these disorders. To better understanding of the pathophysiology and differential diagnosis of schizophrenia and bipolar disorder, this study was c...

journal_title：Disease markers

authors： Galińska-Skok B,Małus A,Konarzewska B,Rogowska-Zach A,Milewski R,Tarasów E,Szulc A,Waszkiewicz N

更新日期：2018-11-25 00:00:00

abstract：BACKGROUND:Tumor cells show alterations in their glycosylation patterns when compared to normal cells. Lectins can be used to evaluate these glycocode changes. Chemiluminescence assay is an effective technique for quantitative analysis of proteins, nucleic acids, and carbohydrates due to its high sensitivity, specifici...

journal_title：Disease markers

authors： Lima LR,Bezerra MF,Almeida SM,Silva LP,Beltrão EI,Carvalho Júnior LB

更新日期：2013-01-01 00:00:00

abstract：:Plasma from bronchial asthma patients and healthy controls was investigated for the content of lipoxygenase products. After lipid extraction using SEP-PAK C18 Cartridges, the lipoxygenase products were measured by Enzyme-Immunoassay. Elevated chemotactic B4 was found in plasma from asthmatic patients with mean value (...

journal_title：Disease markers

authors： Mansour M,Farouk N,el Maragy A,Radwan I,el-Ahmady O

更新日期：1995-03-01 00:00:00

abstract：Objectives:We investigated the influence of spinal cord stimulation (SCS) on IFN-γ, IL-1β, IL-6, TNF-α, IL-10, and TGF-β serum levels in failed back surgery syndrome (FBSS) patients. The study will try to give new insights into the mechanism of SCS action and the role of IFN-γ and other cytokines in neuropathic pain (N...

journal_title：Disease markers

authors： Kamieniak P,Bielewicz J,Grochowski C,Litak J,Bojarska-Junak A,Daniluk B,Trojanowski T

更新日期：2019-01-14 00:00:00

abstract：Aims:The study is aimed at studying the incidence of acute kidney injury (AKI) and exploring the potential predictor for AKI in patients with acute pancreatitis. Methods:A retrospective study adopting a stratified cohort sampling design was performed in a cohort of patients (n = 237) diagnosed with acute pancreatitis ...

journal_title：Disease markers

authors： Chai X,Huang HB,Feng G,Cao YH,Cheng QS,Li SH,He CY,Lu WH,Qin MM

更新日期：2018-11-19 00:00:00

abstract：OBJECTIVE:The present study investigated the prevalence of the IL-28B polymorphisms rs12979860 and rs8099917 in chronic hepatitis B patients from a case study in Eastern Amazonia. METHODS:In total, 65 chronically infected HBV patients and 97 healthy subjects who were anti-HBc and anti-HBs positive (control group) were...

journal_title：Disease markers

authors： Conde SR,Rocha LL,Ferreira VM,Monteiro JC,Filgueiras NK,Lins PA,dos Santos BT,Freitas FB,Graça Eda S,Demachki S,de Araújo MT,Ishak R,Vallinoto AC

更新日期：2014-01-01 00:00:00

abstract：Background:It is reported that miRNAs are aberrantly expressed in patients with pancreatic cancer. However, the diagnostic value of miRNAs in pancreatic cancer remains controversial. The meta-analysis was to access diagnostic accuracy of miRNAs in pancreatic cancer. Methods:PubMed, Scopus, Web of Science, Chinese Nati...

journal_title：Disease markers

authors： Sun X,Zhou X,Zhang Y,Zhu X,Liu H

更新日期：2018-05-15 00:00:00

abstract：:The prevalence of heart failure (HF) due to cardiac remodelling after acute myocardial infarction (AMI) does not decrease regardless of implementation of new technologies supporting opening culprit coronary artery and solving of ischemia-relating stenosis with primary percutaneous coronary intervention (PCI). Numerous...

journal_title：Disease markers

authors： Berezin AE,Berezin AA

更新日期：2020-06-12 00:00:00

abstract：BACKGROUND:Left ventricular dysfunction (LVD), followed by fall in cardiac output is one of the major complications in some coronary artery disease (CAD) patients. The decreased cardiac output over time leads to activation of the renin-angiotensin-aldosterone system which results in vasoconstriction by influencing salt...

journal_title：Disease markers

authors： Mishra A,Srivastava A,Mittal T,Garg N,Mittal B

更新日期：2012-01-01 00:00:00

abstract：Background and Objective:Reduced expression of syndecan-1 (CD138), increased proliferation index, and modifications in the expression of the molecular RANK/RANKL/OPG triad are related to an intensified potential of aggressiveness and invasion of diverse tumors and cysts. The aim was to compare the expression of Ki-67, ...

journal_title：Disease markers

authors： Brito-Mendoza L,Bologna-Molina R,Irigoyen-Camacho ME,Martinez G,Sánchez-Romero C,Mosqueda-Taylor A

更新日期：2018-07-29 00:00:00

abstract：BACKGROUND:We aimed to determine whether serum soluble CD30 (sCD30) could identify recipients at high risk for unfavorable early and late kidney transplant outcomes. METHODS:Serum sCD30 was measured on the day of kidney transplantation and on the 4th day posttransplant. We assessed the value of these measurements in p...

journal_title：Disease markers

authors： Trailin AV,Ostapenko TI,Nykonenko TN,Nesterenko SN,Nykonenko OS

更新日期：2017-01-01 00:00:00

abstract：:Over the last two decades, significant data has been accumulated linking Glutatione S-Transferases (GSTs) with the development of several diseases. Contemporary studies have demonstrated the impact of ethnicity on GST allele frequencies. The aim is to verify if the variability of GST genes reflects population demograp...

journal_title：Disease markers

authors： Polimanti R,Piacentini S,De Angelis F,De Stefano GF,Fuciarelli M

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Lymph node (LN) metastasis was an independent risk factor for stomach cancer recurrence, and the presence of LN metastasis has great influence on the overall survival of stomach cancer patients. Thus, accurate prediction of the presence of lymph node metastasis can provide guarantee of credible prognosis eva...

journal_title：Disease markers

authors： Wu J,Xiao Y,Xia C,Yang F,Li H,Shao Z,Lin Z,Zhao X

更新日期：2017-01-01 00:00:00

abstract：:We aim to identify the mutations of deafness genes using massively parallel DNA sequencing in the 12 Uyghur families. SNPscan method was used to screen against the 124 sites in the common deafness genes in probands. Subjects with SNPscan negativity were subject to massively parallel DNA sequencing for the sequencing o...

journal_title：Disease markers

authors： Chen Y,Lu Y,Kuyaxi P,Cheng J,Zhao J,Zhao Q,Musha P,Zhang H,Yuan H

更新日期：2018-03-05 00:00:00

abstract：Purpose:To determine the frequency of the genotype of signal transducer and activator of transcription protein 3 (STAT3) rs744166, sirtuin (SIRT1) rs12778366, fibroblast growth factor (FGFR2) rs2981582, and advanced glycosylation end product-specific receptor (RAGE) rs1800625 gene polymorphisms in patients with larynge...

journal_title：Disease markers

authors： Uloza V,Tamauskaite T,Vilkeviciute A,Pasvenskaite A,Liutkevicius V,Liutkeviciene R

更新日期：2019-11-12 00:00:00

abstract：Background:Lactate has been widely used as a risk indicator of outcomes in critically ill patients due to its ready measurement and good predictive ability. However, the interconnections between lactate metabolism and glucose metabolism have not been sufficiently explored, yet. In this study, we aimed to investigate wh...

journal_title：Disease markers

authors： Chen X,Bi J,Zhang J,Du Z,Ren Y,Wei S,Ren F,Wu Z,Lv Y,Wu R

更新日期：2019-11-26 00:00:00

abstract：:Nonalcoholic fatty liver disease (NAFLD) is one of the most prevalent chronic liver diseases. Obesity is the most common and well-established risk factor for NAFLD, but there are large interindividual differences in the relationship between weight status and the development of NAFLD. Beta-3-adrenergic receptor (ADRB3)...

journal_title：Disease markers

authors： Sakamoto Y,Oniki K,Kumagae N,Morita K,Otake K,Ogata Y,Saruwatari J

更新日期：2019-12-17 00:00:00

abstract：Background:The C-reactive protein (CRP)/albumin ratio is a useful index used to represent patient inflammation and nutritional status. Elderly patients are at the highest risk for acute kidney injury (AKI). We clarified the impact of the preoperative CRP/albumin ratio on AKI and evaluated the impact of postoperative AK...

journal_title：Disease markers

authors： Yu J,Park JY,Ha S,Hwang JH,Kim YK

更新日期：2020-10-27 00:00:00

abstract：:Cyclin Y (CCNY) is a novel cyclin and almost nothing is known about its role in human cancers. To investigate the clinical significance of serum anti-CCNY autoantibodies in nonsmall-cell lung carcinoma (NSCLC), the serum levels of CCNY protein in 264 patients with NSCLC, 103 patients with tuberculosis, and 89 healthy ...

journal_title：Disease markers

authors： Ma L,Yue W,Teng Y,Zhang L,Gu M,Wang Y

更新日期：2013-01-01 00:00:00

abstract：:Renal cell carcinoma (RCC) is one of the most common genitourinary cancers worldwide. Previous evidence shows that long noncoding RNA (LncRNA) APOC1P1 plays an important role in cancer development. However, the role of LncRNA APOC1P1 in ccRCC remains to be explored. LncRNA APOC1P1 expression in 283 ccRCC tissues and 3...

journal_title：Disease markers

authors： Sun C,Zhou Z,Shi H,Li F,Zhang G

更新日期：2019-12-01 00:00:00

abstract：INTRODUCTION:This study was designed to correlate the serum and gingival crevicular fluid (GCF) levels of progranulin (PGRN) and high sensitivity C-reactive protein (hs CRP) in chronic periodontitis and type 2 diabetes mellitus (DM). DESIGN:PGRN and hs CRP levels were estimated in 3 groups: healthy, chronic periodonti...

journal_title：Disease markers

authors： Priyanka N,Kumari M,Kalra N,Arjun P,Naik SB,Pradeep AR

更新日期：2013-01-01 00:00:00

abstract：:Cytoplasmic islet cell antibodies (ICA) were determined in a group of non-diabetic Caucasian schoolchildren (n = 4208). The prevalence rate for ICA positivity was 1.05 per cent (95 per cent confidence interval: 0.8-1.4 per cent). Analysis of HLA risk factors revealed that HLA-DRB1*03 (p less than 0.01), HLA-DRB1*04 (p...

journal_title：Disease markers

authors： Boehm BO,Seissler J,Glück M,Manfras BJ,Thomas H,Schmidt K,Rudert WA,Usadel KH,Trucco M,Scherbaum WA

更新日期：1991-09-01 00:00:00

abstract：:In a study of multicase RA families, significantly raised frequencies of the HLA antigens DR4, DR1, Bw62, Cw3, A2, A31 and significantly lower frequencies of DR2, DR3, and B8 were found in probands compared to normal controls. When haplotype frequencies were compared between probands and controls, two haplotypes A2-B4...

journal_title：Disease markers

authors： Ollier W,Silman A,Gosnell N,Currey H,Awad J,Doyle P,McCloskey D,Alonso A,Hossain MA,Festenstein H

更新日期：1986-06-01 00:00:00

abstract：:The eukaryotic initiation factor 3 (eIF3) is the largest and most complex translation initiation factor in mammalian cells. It consists of 13 subunits and among which several were implicated to have significant prognostic effects on multiple human cancer entities. To examine the expression profiles of eIF3 subunits an...

journal_title：Disease markers

authors： Wang D,Jia Y,Zheng W,Li C,Cui W

更新日期：2019-12-07 00:00:00