Abstract:
:The surface and cytoplasmic expression of CD1a molecules was analysed by indirect immunofluorescence (IIF) and dot blot assay (DBA) in a panel of 40 acute and chronic leukaemias. Thirty-two per cent of the samples were positive by IIF but, surprisingly, 72 per cent of the patients were positive by DBA, suggesting the intracellular presence of these molecules, CD1b and CD1c were also detected by DBA at similar percentages. Immunocytochemical staining of cytocentrifuge preparations confirmed the intracellular presence of CD1a, CD1b, and CD1c in leukaemic cells of pre-B, B, T, and non-lymphoid lineages.
journal_name
Dis Markersjournal_title
Disease markersauthors
Salamone MC,Roisman FR,Morelli AE,Noli MI,Fainboim Lsubject
Has Abstractpub_date
1990-09-01 00:00:00pages
275-81issue
5eissn
0278-0240issn
1875-8630journal_volume
8pub_type
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