Multiple sclerosis cerebrospinal fluid biomarkers.

abstract：:Hepatitis C virus (HCV) infection prevalence was determined in 34 hepatocellular carcinoma (HCC) patients with underlying liver cirrhosis. Serum alfa-fetoprotein level was found to be more than 1000 ng/ml (3153 +/- 1451) in those patients. Anti-HCV antibodies were detected in 84% of patients sera negative for hepatiti...

journal_title：Disease markers

authors： Mabrouk GM

更新日期：1997-11-01 00:00:00

abstract：BACKGROUND/AIMS:The frequency of HLA markers associated with rapid progression to AIDS was evaluated in Brazilian patients with AIDS exhibiting or not toxoplasmic retinochoroiditis (TRC). METHODS:98 AIDS patients (25 with TRC, 43 with anti-T. gondii antibodies but without TCR, and 30 without anti-T. gondii antibodies ...

journal_title：Disease markers

authors： Demarco AL,Rodrigues Mde L,Figueiredo JF,Deghaide NH,de Menezes MB,Demarco LA,Fernandes AP,Donadi EA

更新日期：2012-01-01 00:00:00

abstract：:Nonenzymatic glycosylation or glycation of macromolecules, especially proteins leading to their oxidation, play an important role in diseases. Glycation of proteins primarily results in the formation of an early stage and stable Amadori-lysine product which undergo further irreversible chemical reactions to form advan...

journal_title：Disease markers

authors： Ansari NA,Moinuddin,Ali R

更新日期：2011-01-01 00:00:00

abstract：Objective:In order to further study the changes of cerebral functional connectivity in patients with toothache (TA), this study used the resting-state functional magnetic resonance imaging (rs-fMRI) technique and degree centrality (DC) analysis method. Methods:Eighteen TA patients (8 males, 10 females) and 18 healthy ...

journal_title：Disease markers

authors： Wu SN,Zhang MY,Shu HY,Liang RB,Ge QM,Pan YC,Zhang LJ,Li QY,Shao Y

更新日期：2020-12-28 00:00:00

abstract：:The nonspecific inflammatory bowel diseases (IBD) represent a heterogeneous group of chronic inflammatory disorders of the gastrointestinal tract, and Leśniowski-Crohn's disease (CD) and ulcerative colitis (UC) are among the two major clinical forms. Despite the great progress in understanding the pathogenesis of thes...

journal_title：Disease markers

authors： Derkacz A,Olczyk P,Komosinska-Vassev K

更新日期：2018-06-11 00:00:00

abstract：:Abnormal phenotypic switch of vascular smooth muscle cell (VSMC) is a hallmark of vascular disorders such as atherosclerosis and restenosis. And this process has been related to remodeling of L-type calcium channel (LTCC). We attempted to investigate whether fluvastatin has any effect on VSMC proliferation and LTCCα 1...

journal_title：Disease markers

authors： Ouyang QF,Han Y,Lin ZH,Xie H,Xu CS,Xie LD

更新日期：2014-01-01 00:00:00

abstract：Background:The pathogenesis of thoracic aortopathy is complex, and much evidence suggests the influence of genetic factors. Some genes with polymorphisms are widely considered critical factors in the initiation and development of aortic aneurysm. The aim of our study was to analyze the association of genetic polymorphi...

journal_title：Disease markers

authors： Gorący I,Grudniewicz S,Safranow K,Ciechanowicz A,Jakubiszyn P,Gorący A,Brykczyński M

更新日期：2020-09-24 00:00:00

abstract：:We evaluated the occurrence of mutations in P53, K-RAS, COX-2, expression of COX-2 and hTERT and relations among clinicopathological signs. P53 mutations were identified in 34.4% of tumours, the majority of them occurring in SCC (squamous cell carcinoma, 55.6%). K-RAS was mutated in 12.2% of NSCLC tumours, the majorit...

journal_title：Disease markers

authors： Strazisar M,Rott T,Glavac D

更新日期：2008-01-01 00:00:00

abstract：:The phenotype of cytosolic Low Molecular Weight Protein Tyrosine Phosphatase (cLMWPTP or ACP1), an enzyme involved in signal transduction of insulin, PDGF and T-cell receptors, has been determined in 71 patients with Crohn's Disease (CD: 37 males and 34 females), 49 patients with Ulcerative Colitis (UC: 27 males and 2...

journal_title：Disease markers

authors： Bottini N,Gloria-Bottini F,Lucarini N,Ronchetti PG,Fontana L

更新日期：2000-01-01 00:00:00

abstract：:Alzheimer's disease (AD) is a neurodegenerative disorder that accounts for nearly 70% of the more than 46 million dementia cases estimated worldwide. Although there is no cure for AD, early diagnosis and an accurate characterization of the disease progression can improve the quality of life of AD patients and their ca...

journal_title：Disease markers

authors： Cassani R,Estarellas M,San-Martin R,Fraga FJ,Falk TH

更新日期：2018-10-04 00:00:00

abstract：:Exposure to asbestos is the main cause of malignant pleural mesothelioma (MPM), a highly aggressive cancer of the pleura. Since the only tools for early detection are based on radiological tests, some authors focused on serum markers (i.e., mesothelin). The aim of this study was the evaluation of new serum biomarkers ...

journal_title：Disease markers

authors： Bonotti A,Foddis R,Landi S,Melaiu O,De Santi C,Giusti L,Donadio E,Ciregia F,Mazzoni MR,Lucacchini A,Bovenzi M,Comar M,Pantani E,Pistelli A,Cristaudo A

更新日期：2017-01-01 00:00:00

abstract：Background:In patients admitted with chest pain and suspected acute coronary syndrome (ACS), it is crucial to early identify those who are at higher risk of adverse events. The study aim was to assess the predictive value of copeptin in patients admitted to the emergency department with chest pain and nonconclusive ECG...

journal_title：Disease markers

authors： Morawiec B,Kawecki D,Przywara-Chowaniec B,Opara M,Muzyk P,Ho L,Tat LC,Gabrysiak A,Muller O,Nowalany-Kozielska E

更新日期：2018-01-24 00:00:00

abstract：:The total plasma concentration of homocysteine is a marker of this amino acid's atherogenic potential. However, the homocysteine pool exists almost entirely as oxidized homocysteine equivalents (OHcyE), composed of homocystine and cysteine-homocysteine disulphides (20-30%), and protein-bound disulphide (70-80%). We ha...

journal_title：Disease markers

authors： Iuliano M,De Tommaso G,Ragone R

更新日期：2009-01-01 00:00:00

abstract：:In this study, we aim to investigate the correlation between circulating tumor cells (CTCs) and the T lymphocyte subsets and NK cells in peripheral blood in non-small-cell lung cancer (NSCLC). The peripheral blood CTCs were determined by SET-iFISH. Flow cytometry was used to determine the distribution of T lymphocyte ...

journal_title：Disease markers

authors： Ye L,Zhang F,Li H,Yang L,Lv T,Gu W,Song Y

更新日期：2017-01-01 00:00:00

abstract：:Alcohol abuse is one of the most common risk factor for chronic pancreatitis, but the underlying pathophysiological mechanisms remain unclear. The aim of this study was to identify genes that contribute to susceptibility or resistance for alcoholic chronic pancreatitis by screening the whole genome. Sixty-five patient...

journal_title：Disease markers

authors： Kitahara K,Kawa S,Katsuyama Y,Umemura T,Ozaki Y,Takayama M,Arakura N,Ota M

更新日期：2008-01-01 00:00:00

abstract：:Transforming growth factor β1 (TGF-β1) is an important mediator in Chagas disease. Furthermore, patients with higher TGF-β1 serum levels show a worse clinical outcome. Gene polymorphism may account for differences in cytokine production during infectious diseases. We tested whether TGFB1 polymorphisms could be associa...

journal_title：Disease markers

authors： Ferreira RR,Madeira FDS,Alves GF,Chambela MDC,Curvo EOV,Moreira ADS,Almeida de Sá R,Mendonça-Lima L,Cabello PH,Bailly S,Feige JJ,Araujo-Jorge TC,Saraiva RM,Waghabi MC

更新日期：2018-02-18 00:00:00

abstract：:Immunological and immunogenetic investigations are described in a group of 28 women with a history of unexplained recurrent (greater than or equal to 3 consecutive) spontaneous abortions (RSA). Compared with female blood donor controls, recurrent aborters had significantly elevated mean serum complement C4 (p less tha...

journal_title：Disease markers

authors： Kilpatrick DC,Liston WA,Neill G,Maxwell C

更新日期：1989-04-01 00:00:00

abstract：BACKGROUND:Papillary thyroid carcinoma (PTC), follicular thyroid adenoma (FTA), and thyroid nodular hyperplasia (TNH) are the most frequent diseases of the thyroid gland. Previous studies described the involvement of dipeptidyl-peptidase IV (DPPIV/CD26) in the development of thyroid neoplasia and proposed it as an addi...

journal_title：Disease markers

authors： Larrinaga G,Blanco L,Errarte P,Beitia M,Sanz B,Perez I,Irazusta A,Sánchez CE,Santaolalla F,Andrés L,López JI

更新日期：2013-01-01 00:00:00

abstract：Background:Obese women with gestational diabetes mellitus (GDM) have a higher risk of adverse outcomes than women with obesity or GDM alone. Our study is aimed at investigating the discriminatory power of circulatory Wnt1-inducible signaling pathway protein-1 (WISP1), a novel adipocytokine, on the copresence of prepreg...

journal_title：Disease markers

authors： Liu L,Hu J,Yang L,Wang N,Liu Y,Wei X,Gao M,Wang Y,Ma Y,Wen D

更新日期：2020-04-14 00:00:00

abstract：:Oncogenic activation of the Wnt/ β -catenin signaling pathway is common in human cancers. The secreted frizzled-related proteins (SFRPs) function as negative regulators of Wnt signaling and have important implications in carcinogenesis. Because there have been no reports about the role of SFRP3 in hepatocellular carci...

journal_title：Disease markers

authors： Lin YW,Shih YL,Lien GS,Suk FM,Hsieh CB,Yan MD

更新日期：2014-01-01 00:00:00

abstract：Background:It is reported that miRNAs are aberrantly expressed in patients with pancreatic cancer. However, the diagnostic value of miRNAs in pancreatic cancer remains controversial. The meta-analysis was to access diagnostic accuracy of miRNAs in pancreatic cancer. Methods:PubMed, Scopus, Web of Science, Chinese Nati...

journal_title：Disease markers

authors： Sun X,Zhou X,Zhang Y,Zhu X,Liu H

更新日期：2018-05-15 00:00:00

abstract：:The frequency and the distribution of HLA-B27 subtypes in spondylarthropathy (SpA) patients and controls were investigated in a sample Turkish population. B27 subtyping was performed by PCR-SSP method in two groups: 49 unrelated HLA-B27 positive Turkish patients with the diagnosis of SpA according to the European Spon...

journal_title：Disease markers

authors： Oguz FS,Ocal L,Diler AS,Ozkul H,Asicioglu F,Kasapoglu E,Bozkurt G,Konice M,Carin M

更新日期：2004-01-01 00:00:00

abstract：:GROβ (CXCL2) is a chemokine produced by endotoxin-treated macrophages that mediates inflammation and tumor development. However, little is known about GROβ expression in gastrointestinal stromal tumors (GIST) or the relationship between GROβ expression and clinical attributes of GIST. GROβ expression was examined via ...

journal_title：Disease markers

authors： Zhao H,Zhu H,Jin Q,Zhang S,Wang W,Wang D,Huang J

更新日期：2015-01-01 00:00:00

abstract：Purpose:To determine the frequency of the genotype of signal transducer and activator of transcription protein 3 (STAT3) rs744166, sirtuin (SIRT1) rs12778366, fibroblast growth factor (FGFR2) rs2981582, and advanced glycosylation end product-specific receptor (RAGE) rs1800625 gene polymorphisms in patients with larynge...

journal_title：Disease markers

authors： Uloza V,Tamauskaite T,Vilkeviciute A,Pasvenskaite A,Liutkevicius V,Liutkeviciene R

更新日期：2019-11-12 00:00:00

abstract：Background:The ratio of early mitral inflow velocity to the global diastolic strain rate (E/E'sr) and global longitudinal systolic strain (GLS) of the left ventricle (LV) are emerging indices of diastolic and systolic functions, respectively, for the LV. Their prognostic significance in the prediction of mortality and ...

journal_title：Disease markers

authors： Huang JC,Su HM,Wu PY,Lee JJ,Lee WH,Chen SC,Chiu YW,Hsu YL,Chang JM,Chen HC

更新日期：2019-09-05 00:00:00

abstract：:IGF2 is the first gene discovered to be imprinted and expressed exclusively from the paternal allele in both human and mouse. IGF2 is also the first imprinted gene displaying loss of imprinting (LOI) or aberrant imprinting in human cancers. Evidently, LOI or reactivation of the maternal allele of IGF2 is associated wi...

journal_title：Disease markers

authors： Cui H

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Lymph node (LN) metastasis was an independent risk factor for stomach cancer recurrence, and the presence of LN metastasis has great influence on the overall survival of stomach cancer patients. Thus, accurate prediction of the presence of lymph node metastasis can provide guarantee of credible prognosis eva...

journal_title：Disease markers

authors： Wu J,Xiao Y,Xia C,Yang F,Li H,Shao Z,Lin Z,Zhao X

更新日期：2017-01-01 00:00:00

abstract：:Immunization with a pandemic influenza A H1N1 2009 was recommended for HIV-infected patients. However, there is limited information concerning the impact of immunization with this vaccine on immune activation and HIV viral replication. In this study, 45 HIV-infected children and adolescents receiving antiretroviral th...

journal_title：Disease markers

authors： Onlamoon N,Unpol P,Boonchan M,Sukapirom K,Wittawatmongkol O,Chokephaibulkit K,Ammaranond P,Pattanapanyasat K

更新日期：2013-01-01 00:00:00

abstract：:To identify the novel, noninvasive biomarkers to assess the outcome and prognosis of breast cancer (BC), patients with high sensitivity and specificity are greatly desired. Herein, the miRNA expression profile and matched clinical features of BC patients were extracted from The Cancer Genome Atlas (TCGA) database. The...

journal_title：Disease markers

authors： Tang J,Ma W,Zeng Q,Tan J,Cao K,Luo L

更新日期：2019-12-30 00:00:00

abstract：:The surface and cytoplasmic expression of CD1a molecules was analysed by indirect immunofluorescence (IIF) and dot blot assay (DBA) in a panel of 40 acute and chronic leukaemias. Thirty-two per cent of the samples were positive by IIF but, surprisingly, 72 per cent of the patients were positive by DBA, suggesting the ...

journal_title：Disease markers

authors： Salamone MC,Roisman FR,Morelli AE,Noli MI,Fainboim L

更新日期：1990-09-01 00:00:00