Plasma Brain-Derived Neurotrophic Factor as a Biomarker for the Main Types of Mild Neurocognitive Disorders and Treatment Efficacy: A Preliminary Study.

abstract：Objectives:To explore the impact of volume change in the fractionated tracking of stereotactic radiotherapy on the results of synchronous, respiratory tracking algorithm using CyberKnife. Methods:A total of 38 lung tumor patients receiving stereotactic radiotherapy at our center from March 2018 to October 2019 were co...

journal_title：Disease markers

authors： Li GQ,Wang Y,Qiu MJ,Yang J,Peng ZJ,Zhang S,Fang X,Yang SL

更新日期：2020-01-11 00:00:00

abstract：:Kinesin family member 20A (KIF20A) has been recently reported to be upregulated and associated with increased invasiveness and metastasis in several malignancies. However, the role of KIF20A in colorectal cancer (CRC) is still unclear. This study is aimed at investigating the potential roles of KIF20A in the developme...

journal_title：Disease markers

authors： Zhang Q,Di J,Ji Z,Mi A,Li Q,Du X,Wang A,Wang A,Qin C

更新日期：2020-07-08 00:00:00

abstract：BACKGROUND:A novel swine-origin influenza A H1N1 virus (S-OIV) caused human infection and acute respiratory illness in 2009, resulting in an influenza pandemic. OBJECTIVES:This study characterized the immune responses of S-OIV infection in pediatric patients at risk of pulmonary complications. METHODS:All enrolled pe...

journal_title：Disease markers

authors： Wang SM,Liao YT,Hu YS,Ho TS,Shen CF,Wang JR,Lin YS,Liu CC

更新日期：2014-01-01 00:00:00

abstract：:Introduction. Chronic Periodontitis (CP) is suggested to be related to gene variations. Present study aims to quantitatively estimate the association between interleukin-6- (IL-6-) 174G/C polymorphism and CP susceptibility. Materials and Methods. Pubmed, Embase, and Web of Science were searched up to May 2016. The met...

journal_title：Disease markers

authors： Zhu J,Guo B,Fu M,Guo W,Yuan Y,Yuan H,Zhang S,Yu H

更新日期：2016-01-01 00:00:00

abstract：:This study was undertaken to assess the biochemical changes induced in chronic schistosomiasis and/or chronic HCV, as well as to pinpoint the most significant parameters which could be used as dependable indices for the differentiation of single and coupled infections with or without liver cirrhosis. The selected pati...

journal_title：Disease markers

authors： Fahim FA,Esmat AY,Hassan GK,Abdel-Bary A

更新日期：2000-01-01 00:00:00

abstract：:Over the last two decades, significant data has been accumulated linking Glutatione S-Transferases (GSTs) with the development of several diseases. Contemporary studies have demonstrated the impact of ethnicity on GST allele frequencies. The aim is to verify if the variability of GST genes reflects population demograp...

journal_title：Disease markers

authors： Polimanti R,Piacentini S,De Angelis F,De Stefano GF,Fuciarelli M

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Autism is among the commonest neurodevelopmental childhood disorders worldwide; its aetiology is still unknown. Iron metabolism alteration in the central nervous system is recently implicated as a risk factor for several neurodegenerative disorders. Haemochromatosis HFE gene polymorphisms (p.H63D and p.C282Y...

journal_title：Disease markers

authors： Gebril OH,Meguid NA

更新日期：2011-01-01 00:00:00

abstract：:Because tandem mass spectrometry- (MS/MS-) based newborn screening identifies many suspicious cases of fatty acid oxidation and carnitine cycle disorders, a simple, noninvasive test is required to confirm the diagnosis. We have developed a novel method to evaluate the metabolic defects in peripheral blood mononuclear ...

journal_title：Disease markers

authors： Yuasa M,Hata I,Sugihara K,Isozaki Y,Ohshima Y,Hara K,Tajima G,Shigematsu Y

更新日期：2019-02-07 00:00:00

abstract：:Biomarker measurements now support key decisions throughout the drug development process, from lead optimization to regulatory approvals. They are essential for documenting exposure-response relationships, specificity and potency toward the molecular target, untoward effects, and therapeutic applications. In a broader...

journal_title：Disease markers

authors： Swanson BN

更新日期：2002-01-01 00:00:00

abstract：Objectives:We investigated the influence of spinal cord stimulation (SCS) on IFN-γ, IL-1β, IL-6, TNF-α, IL-10, and TGF-β serum levels in failed back surgery syndrome (FBSS) patients. The study will try to give new insights into the mechanism of SCS action and the role of IFN-γ and other cytokines in neuropathic pain (N...

journal_title：Disease markers

authors： Kamieniak P,Bielewicz J,Grochowski C,Litak J,Bojarska-Junak A,Daniluk B,Trojanowski T

更新日期：2019-01-14 00:00:00

abstract：Background:Preeclamptic pregnancies often present an intensified inflammatory state associated with the nuclear activity of NFκB. NEMO is an essential regulator of nuclear factor kappa B (NFκB) in cytoplasmic and nuclear cellular compartments. The aim of the present study is to examine the level and localization of the...

journal_title：Disease markers

authors： Sakowicz A,Lisowska M,Biesiada L,Płuciennik E,Gach A,Rybak-Krzyszkowska M,Huras H,Sakowicz B,Romanowicz H,Piastowska-Ciesielska AW,Grzesiak M,Pietrucha T

更新日期：2019-01-02 00:00:00

abstract：:RARβ plays a critical role in cancer progression and is associated with several types of human cancer. It remains unclear, however, whether it is linked to the clinicopathological parameters of colorectal cancer (CRC). We therefore determined the expression of RARβ protein in patients with primary CRC and examined its...

journal_title：Disease markers

authors： Wang W,Liu S,Jiang C,Wang Y,Zhu H,Wang X

更新日期：2019-03-03 00:00:00

abstract：BACKGROUND:Stroke subtype diagnosis leads to specific therapies to reduce recurrences. Because nearly one third of patients remain with unknown etiology after a complete screening workup, we aim to investigate whether molecular markers of myocardial damage were associated with cardioembolic stroke and if they were usef...

journal_title：Disease markers

authors： Rodríguez-Yáñez M,Sobrino T,Blanco M,de la Ossa NP,Brea D,Rodríguez-González R,Leira R,Dávalos A,Castillo J

更新日期：2009-01-01 00:00:00

abstract：:In a study of multicase RA families, significantly raised frequencies of the HLA antigens DR4, DR1, Bw62, Cw3, A2, A31 and significantly lower frequencies of DR2, DR3, and B8 were found in probands compared to normal controls. When haplotype frequencies were compared between probands and controls, two haplotypes A2-B4...

journal_title：Disease markers

authors： Ollier W,Silman A,Gosnell N,Currey H,Awad J,Doyle P,McCloskey D,Alonso A,Hossain MA,Festenstein H

更新日期：1986-06-01 00:00:00

abstract：:Salivary oxidative stress markers represent a promising tool for monitoring of oral diseases. Saliva can often be contaminated by blood, especially in patients with periodontitis. The aim of our study was to examine the impact of blood contamination on the measurement of salivary oxidative stress markers. Saliva sampl...

journal_title：Disease markers

authors： Kamodyová N,Baňasová L,Janšáková K,Koborová I,Tóthová Ľ,Stanko P,Celec P

更新日期：2015-01-01 00:00:00

abstract：Background:The pathogenesis of thoracic aortopathy is complex, and much evidence suggests the influence of genetic factors. Some genes with polymorphisms are widely considered critical factors in the initiation and development of aortic aneurysm. The aim of our study was to analyze the association of genetic polymorphi...

journal_title：Disease markers

authors： Gorący I,Grudniewicz S,Safranow K,Ciechanowicz A,Jakubiszyn P,Gorący A,Brykczyński M

更新日期：2020-09-24 00:00:00

abstract：:Vitamin D plays a role in central nervous system (CNS) development. Recent literature focused on vitamin D status in children and adolescents with autism spectrum disorder (ASD), but with inconsistent results. Our case-control study is aimed at evaluating serum 25-hydroxyl-vitamin D (25(OH)D) concentration in children...

journal_title：Disease markers

authors： Petruzzelli MG,Marzulli L,Margari F,De Giacomo A,Gabellone A,Giannico OV,Margari L

更新日期：2020-09-18 00:00:00

abstract：:The frequency and the distribution of HLA-B27 subtypes in spondylarthropathy (SpA) patients and controls were investigated in a sample Turkish population. B27 subtyping was performed by PCR-SSP method in two groups: 49 unrelated HLA-B27 positive Turkish patients with the diagnosis of SpA according to the European Spon...

journal_title：Disease markers

authors： Oguz FS,Ocal L,Diler AS,Ozkul H,Asicioglu F,Kasapoglu E,Bozkurt G,Konice M,Carin M

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:The association of the apolipoprotein (Apo E) -epsilon4 allele to neurodegenerative diseases such as Parkinson's disease (PD) has been analyzed in several studies. This association has been identified by amyloid deposits and neurofibrillary tangles in the brains of patients with neurodegenerative diseases. ...

journal_title：Disease markers

authors： Gallegos-Arreola MP,Figuera LE,Ortiz GG,Jiménez-Gil FJ,Ramírez-Vega J,Ruíz-Sandoval JL,Puebla-Pérez AM,Troyo-Sanroman R,García-Ortiz JE,Sanchez-Corona J,Zúñiga-González GM

更新日期：2009-01-01 00:00:00

abstract：:PIZ allele frequencies were defined by PCR amplification and hybridization using a PIZ SSO (sequence specific oligonucleotide) probe. The groups studied included 64 normal controls, 104 subjects with rheumatoid arthritis (RA) without any extra-articular features, 29 of whom had severe arthritis and 31 of whom had mild...

journal_title：Disease markers

authors： Steers G,McMahon MJ,Grennan DM,Hillarby MC

更新日期：1992-05-01 00:00:00

abstract：BACKGROUND:Genetics of non-alcoholic fatty liver (NAFLD) in Asian Indians has been inadequately investigated. This study aims to determine the association of the 1784G>C polymorphism in the SREBP-2 gene with NAFLD in Asian Indians in north India. METHODS:In this study, (n=335); 162 obese with NAFLD, 91 obese without N...

journal_title：Disease markers

authors： Bhatt SP,Nigam P,Misra A,Guleria R,Luthra K,Vaidya M,Jain SK,Pasha MA

更新日期：2011-01-01 00:00:00

abstract：:Immunization with a pandemic influenza A H1N1 2009 was recommended for HIV-infected patients. However, there is limited information concerning the impact of immunization with this vaccine on immune activation and HIV viral replication. In this study, 45 HIV-infected children and adolescents receiving antiretroviral th...

journal_title：Disease markers

authors： Onlamoon N,Unpol P,Boonchan M,Sukapirom K,Wittawatmongkol O,Chokephaibulkit K,Ammaranond P,Pattanapanyasat K

更新日期：2013-01-01 00:00:00

abstract：:Cytoskeletal rearrangement occurs in variety of cellular processes and involves a wide spectrum of proteins. Gelsolin super family proteins control actin organization by severing and capping filament ends and nucleating actin assembly. Gelsolin is the founding member of this family and plays important role in pathogen...

journal_title：Disease markers

authors： Baig RM,Mahjabeen I,Sabir M,Masood N,Ali K,Malik FA,Kayani MA

更新日期：2013-01-01 00:00:00

abstract：Purpose:To investigate the association of galectin-3 (Gal-3) and soluble ST2 (sST2) and their follow-up changes with the development of heart failure (HF) and echocardiographic parameters of HF (ejection fraction, atrial and ventricular size, left ventricular hypertrophy, e', and E/e') in patients with ST-segment eleva...

journal_title：Disease markers

authors： Tymińska A,Kapłon-Cieślicka A,Ozierański K,Budnik M,Wancerz A,Sypień P,Peller M,Balsam P,Opolski G,Filipiak KJ

更新日期：2019-10-10 00:00:00

abstract：:A study of MHC class I, II, and III markers in a group of southern Chinese in Hong Kong is reported. HLA antigen frequencies and complement allele frequencies are given, together with statistically significant pair-wise co-occurrences. Over half of the statistically significant positive and negative linkage disequilib...

journal_title：Disease markers

authors： Hawkins BR,Serjeantson SW,Higgins DA

更新日期：1988-10-01 00:00:00

abstract：Background:With the development of new drug combinations and targeted treatments for multiple types of cancer, the ability to stratify categories of patient populations and to develop companion diagnostics has become increasingly important. A panel of 325 RNA biomarkers was selected based on cancer-related biological p...

journal_title：Disease markers

authors： Delmonico L,Attiya S,Chen JW,Obenauer JC,Goodwin EC,Fournier MV

更新日期：2019-05-14 00:00:00

abstract：:Lung disease due to non-tuberculous mycobacteria (NTM) is a poorly understood condition that is difficult to treat. Treatment remains problematic as few tools are available to help clinicians monitor disease progression or predict treatment outcome. In this study, plasma levels of several inflammatory molecules and th...

journal_title：Disease markers

authors： Lim A,Allison C,Tan DB,Oliver B,Price P,Waterer G

更新日期：2010-01-01 00:00:00

abstract：:High levels of cardiovascular fitness (CRF) and physical activity (PA) are associated with decreased mortality and risk to develop metabolic diseases. The independent contributions of CRF and PA to metabolic disease risk factors are unknown. We tested the hypothesis that runners who run consistently >50 km/wk and/or >...

journal_title：Disease markers

authors： Laye MJ,Nielsen MB,Hansen LS,Knudsen T,Pedersen BK

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Up to 43% of HIV-infected patients co-infected with Mycobacterium tuberculosis experience exacerbations of tuberculosis (TB) after commencing antiretroviral therapy (ART). These are termed immune restoration disease (IRD). It is unclear why individual susceptibility varies. OBJECTIVE:We investigate if singl...

journal_title：Disease markers

authors： Affandi JS,Kumar M,Agarwal U,Singh S,Price P

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVE:To investigate whether single nucleotide polymorphisms (SNPs) in the Mn-superoxide dismutase gene (SOD2) underlie the susceptibility to noise-induced hearing loss (NIHL). METHODS:Audiometric data from 2400 Chinese Han workers who exposed to occupational noise were analyzed. DNA samples were collected from th...

journal_title：Disease markers

authors： Liu YM,Li XD,Guo X,Liu B,Lin AH,Ding YL,Rao SQ

更新日期：2010-01-01 00:00:00