Abstract:
:Analyses of reassortant and parental strains of BTV serotypes 3 and 10, in serum neutralization tests, confirmed the major role of outer capsid protein VP2 in determination of virus serotype and its involvement in serum neutralization. However, a reassortant BTV strain (R70), containing protein VP5 derived from BTV 3 and VP2 derived from BTV 10, cross-neutralized with both parental virus strains (BTV 3 and BTV 10). It is concluded that VP5 also plays some part in serotype determination of these virus isolates, as analyzed by serum-neutralization, but its role may be less significant than that of VP2.
journal_name
Virologyjournal_title
Virologyauthors
Mertens PP,Pedley S,Cowley J,Burroughs JN,Corteyn AH,Jeggo MH,Jennings DM,Gorman BMdoi
10.1016/0042-6822(89)90447-9subject
Has Abstractpub_date
1989-06-01 00:00:00pages
561-5issue
2eissn
0042-6822issn
1096-0341journal_volume
170pub_type
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