The genome-linked protein of cowpea mosaic virus is coded by RNA from the bottom component.

abstract：:We previously provided evidence for a model of herpes simplex virus type 1 (HSV-1) entry by a cascade of interactions between components of the virion envelope and cellular plasma membrane (Fuller and Lee, 1992, J. Virol. 66, 5002-5012). In this report we have determined entry kinetics of wild-type HSV-1 into two high...

journal_title：Virology

authors： McClain DS,Fuller AO

更新日期：1994-02-01 00:00:00

abstract：:Specific binding sites for Epstein-Barr virus (EBV) nuclear antigen (EBNA-1), isolated and semipurified from EBV-transformed nonproductive Raji cells, were visualized on the molecule of EBV DNA by electron microscopy and mapped. Two measures had to be applied to counteract the limited purity of the EBNA-1 preparation:...

journal_title：Virology

authors： Reischig J,Bartsch D,Polack A,Vonka V,Hirsch I

更新日期：1987-10-01 00:00:00

abstract：:Cucumber mosaic virus (CMV), generated from biologically active cDNA clones of Fny-CMV RNA 1 plus 2 and Sny-CMV RNA 3, derived from the Fny- and Sny-strains of CMV, was able to infect tobacco but not squash plants systemically. In squash, viral RNA, movement protein, and coat protein all accumulated in the inoculated ...

journal_title：Virology

authors： Kaplan IB,Gal-On A,Palukaitis P

更新日期：1997-04-14 00:00:00

abstract：:Progressive reorganization and depolymerization of microtubules corresponded with virus-induced rounding of Autographa californica M nuclear polyhedrosis virus (AcMNPV)-infected Spodoptera frugiperda IPLB-Sf-21 cells, suggesting that microtubules were instrumental in maintaining the normal shape of these cells. Depoly...

journal_title：Virology

authors： Volkman LE,Zaal KJ

更新日期：1990-03-01 00:00:00

abstract：:Strong evidence indicates that virions of mammalian reoviruses undergo proteolytic processing by acid-dependent cellular proteinases as an essential step in productive infection. Proteolytic processing takes the form of a series of cleavages of outer-capsid proteins final sigma3 and mu1/mu1C. Previous studies showed a...

journal_title：Virology

authors： Kothandaraman S,Hebert MC,Raines RT,Nibert ML

更新日期：1998-11-25 00:00:00

abstract：:Dengue viruses (DENV) are the most important arboviral pathogens in tropical and subtropical regions throughout the world. DENV transmission includes both a sylvatic, enzootic cycle between nonhuman primates and arboreal mosquitoes of the genus Aedes, and an urban, endemic/epidemic cycle between Aedes aegypti, a mosqu...

journal_title：Virology

authors： Vasilakis N,Shell EJ,Fokam EB,Mason PW,Hanley KA,Estes DM,Weaver SC

更新日期：2007-02-20 00:00:00

abstract：:Human papillomavirus type 6 (HPV 6) DNA was detected in an episomal form in DNA extracted from an invasive squamous carcinoma of the vulva. The viral DNA, designated HPV6-T70, was molecularly cloned. Restriction analysis of the HPV6-T70 genome revealed an insertion of approximately 35 bp in the 5' portion of the upstr...

journal_title：Virology

authors： Kasher MS,Roman A

更新日期：1988-07-01 00:00:00

abstract：:HPV-16 is the major causes of cervical cancer. Persistence of infection is a necessary event for progression of the infection to cancer. Among other factors, virus persistence is due the viral proteins fighting the immune response. HPV-16 E5 down-regulates MHC/HLA class I, which is much reduced on the cell surface and...

journal_title：Virology

authors： Campo MS,Graham SV,Cortese MS,Ashrafi GH,Araibi EH,Dornan ES,Miners K,Nunes C,Man S

更新日期：2010-11-10 00:00:00

abstract：:Three proteins, reacting specifically with sera raised against synthetic peptides identical to C-terminal amino acid sequences in alfalfa mosaic virus (AIMV) proteins P1, P2, and P3 translated in vitro from the AIMV RNAs 1, 2, and 3, respectively, were for the first time observed in tobacco and cowpea protoplasts. Par...

journal_title：Virology

authors： van Pelt-Heerschap H,Verbeek H,Huisman MJ,Sue Loesch-Fries L,Van Vloten-Doting L

更新日期：1987-11-01 00:00:00

abstract：:The initiation of reverse transcription of the human immunodeficiency virus type 1 (HIV-1) genome requires cellular tRNA(Lys,3) as a primer and occurs at a site in the viral RNA genome, designated as the primer binding site (PBS), which is complementary to the 3'-terminal 18 nucleotides of tRNA(Lys,3). We previously d...

journal_title：Virology

authors： Zhang Z,Kang SM,LeBlanc A,Hajduk SL,Morrow CD

更新日期：1996-12-15 00:00:00

abstract：:To accomplish their viral life cycle, lentiviruses such as HIV highjack host proteins, the so-called cellular co-factors of replication. Lens Epithelium-derived Growth factor (LEDGF/p75), a transcriptional co-activator, is a co-factor of HIV-integrase (IN) and is required for the tethering and correct integration of t...

journal_title：Virology

authors： Christ F,Debyser Z

更新日期：2013-01-05 00:00:00

abstract：:It is likely that phylogroup 2 lyssaviruses circulate within bat reservoirs. We adapted a pseudotype (pt) neutralisation assay (PNA) to a multiplex format enabling serosurveillance for Lagos bat virus (LBV), Mokola virus (MOKV) and West Caucasian bat virus (WCBV) in a potential reservoir, the African straw-coloured fr...

journal_title：Virology

authors： Wright E,Hayman DT,Vaughan A,Temperton NJ,Wood JL,Cunningham AA,Suu-Ire R,Weiss RA,Fooks AR

更新日期：2010-12-20 00:00:00

abstract：:The synthesis and processing of the nucleocapsid protein (pp60) of the JHM strain of murine coronaviruses were examined. Pulse-chase experiments showed that pp60 was synthesized initially as a protein of approximately 57,000 in molecular weight (p57). Immunoprecipitation using mouse anti-JHMV antiserum indicated that ...

journal_title：Virology

authors： Stohlman SA,Fleming JO,Patton CD,Lai MM

更新日期：1983-10-30 00:00:00

abstract：:Natural infection and vaccination with a live-attenuated measles virus (MV) induce CD8(+) T-cell-mediated immune responses that may play a central role in controlling MV infection. In this study, we show that newly identified human HLA-A2 epitopes from MV hemagglutinin (H) and fusion (F) proteins induced protective im...

journal_title：Virology

authors： Oh S,Stegman B,Pendleton CD,Ota MO,Pan CH,Griffin DE,Burke DS,Berzofsky JA

更新日期：2006-09-01 00:00:00

abstract：:While the 2009 pandemic H1N1 virus has become established in the human population as a seasonal influenza virus, continued adaptation may alter viral virulence. Here, we passaged a 2009 pandemic H1N1 virus (A/Changchun/01/2009) in mice. Serial passage in mice generated viral variants with increased virulence. Adapted ...

journal_title：Virology

authors： Yu Z,Cheng K,Sun W,Zhang X,Li Y,Wang T,Wang H,Zhang Q,Xin Y,Xue L,Zhang K,Huang J,Yang S,Qin C,Wilker PR,Yue D,Chen H,Gao Y,Xia X

更新日期：2015-12-01 00:00:00

abstract：:RNA analysis by nondenaturing polyacrylamide gel electrophoresis and Northern blot hybridization of avocado chloroplasts purified from protoplasts of leaves infected by avocado sunblotch viroid (ASBVd) revealed the main ASBVd-specific bands found previously in preparations of total leaf RNA: the monomeric, dimeric and...

journal_title：Virology

authors： Navarro JA,Darós JA,Flores R

更新日期：1999-01-05 00:00:00

abstract：:The genome of Lelystad virus (LV), a positive-strand RNA virus, is 15 kb in length and contains 8 open reading frames (ORFs) that encode putative viral proteins. ORFs 2 to 7 were cloned in plasmids downstream of the Sp6 RNA polymerase promoter, and the translation of transcripts generated in vitro yielded proteins tha...

journal_title：Virology

authors： Meulenberg JJ,Petersen-den Besten A,De Kluyver EP,Moormann RJ,Schaaper WM,Wensvoort G

更新日期：1995-01-10 00:00:00

abstract：:Phosphorylation of I kappa Bs--the cytoplasmic inhibitors of the NF-kappa B transcription factors--is the key event which triggers activation of the NF-kappa B cascade. Signal-mediated phosphorylation of I kappa B alpha is mediated by a multiprotein complex, the I kappa B kinase (IKK) complex, which is composed of at ...

journal_title：Virology

authors： Le Page C,Popescu O,Génin P,Lian J,Paquin A,Galipeau J,Hiscott J

更新日期：2001-08-01 00:00:00

abstract：:The rate of synthesis in vivo and the steady-state level of mRNA of four "model" herpes simplex virus type 1 (HSV-1) genes were measured as a function of high levels of alpha-gene products. The genes studied were ICP4 (alpha), deoxy-UTPase (beta), VP5 (beta gamma), and glycoprotein C (gC, gamma). Accumulation of high ...

journal_title：Virology

authors： Zhang YF,Devi-Rao GB,Rice M,Sandri-Goldin RM,Wagner EK

更新日期：1987-03-01 00:00:00

abstract：:In this report, we examined the abilities and requirements of heterologous Gag proteins to functionally complement each other to support viral replication. Two distantly related gammaretroviruses, murine leukemia virus (MLV) and spleen necrosis virus (SNV), were used as a model system because SNV proteins can support ...

journal_title：Virology

authors： Lee SK,Boyko V,Hu WS

更新日期：2007-04-10 00:00:00

abstract：:A human B-lymphoid cell line, designated TG8, which does not express detectable levels of the EBV (Epstein-Barr virus)-associated nuclear antigen (EBNA), yet carries an average of one to two plasmid copies of the P3HR-1 EBV genome has been identified. TG8 can be superinfected by B95-8 EBV, resulting in up to 60-70% of...

journal_title：Virology

authors： Reisman D,Sugden B

更新日期：1984-08-01 00:00:00

abstract：:All lepidopteran baculovirus genomes sequenced to date encode a viral fibroblast growth factor homolog (vfgf), suggesting that vfgf may play an important role in the infection cycle of lepidopteran baculoviruses. Here, we describe the characterization of a Bombyx mori nucleopolyhedrovirus (BmNPV) mutant lacking functi...

journal_title：Virology

authors： Katsuma S,Horie S,Daimon T,Iwanaga M,Shimada T

更新日期：2006-11-10 00:00:00

abstract：:Proviruses were cloned directly from a cat that developed neurological disorders approximately 28 months after inoculation with a molecularly cloned, minimally pathogenic subgroup A feline leukemia virus (FeLV-A). In addition to FeLV-A proviruses that were nearly identical to the inoculated virus, we detected a subgro...

journal_title：Virology

authors： Boomer S,Gasper P,Whalen LR,Overbaugh J

更新日期：1994-11-01 00:00:00

abstract：:We have previously shown that the Edmonston strain of measles virus enters and is released preferentially at the apical surfaces of polarized epithelial cells. Small amounts of virus were found to be released at the basal surface. In the present study, we passaged the virus in polarized cells and characterized the pas...

journal_title：Virology

authors： Blau DM,Compans RW

更新日期：1997-05-12 00:00:00

abstract：:Infection of microglial cells by the human immunodeficiency virus (HIV) is supposed to play an important role in the pathogenesis of AIDS-related central nervous system (CNS) complications. So far, however, experimental data about interactions between HIV and ramified microglia from the adult CNS were only occasionall...

journal_title：Virology

authors： Hein A,Martin JP,Koehren F,Bingen A,Dörries R

更新日期：2000-03-15 00:00:00

abstract：:The phosphoprotein (P) of bovine respiratory syncytial virus (BRSV) is a multifunctional protein that plays a central role in transcription and replication of the viral genomic RNA. To investigate the domains and specific residues involved in different activities of the P protein, we generated a total of 22 deletion a...

journal_title：Virology

authors： Khattar SK,Yunus AS,Collins PL,Samal SK

更新日期：2001-07-05 00:00:00

abstract：:The measles virus (MV) phosphoprotein (P) gene encodes three proteins, P, C, and V. The V protein is synthesized by pseudo-templated transcription, also designated as RNA editing: during P gene transcription one G residue is inserted at a defined position in about 50% of the mRNAs. To study the importance of sequence ...

journal_title：Virology

authors： Schneider H,Kaelin K,Billeter MA

更新日期：1997-01-20 00:00:00

abstract：:In this report, we present the DNA sequence and transcriptional characterization of a gene (IR5) that maps within each of the inverted repeat (IR) segments of the equine herpesvirus type 1 (EHV-1) genome. The IR5 open reading frame (ORF) is located within both IR sequences (nucleotides 9932-10,642 of the IR). DNA sequ...

journal_title：Virology

authors： Holden VR,Yalamanchili RR,Harty RN,O'Callaghan DJ

更新日期：1992-06-01 00:00:00

abstract：:All primates studied to date produce retroviral-like particles in their placentae. We have purified these particles from two primate species, one Old World (human) and one New World (marmoset), and have identified the retroviral sequences which are packaged into these particles. Three families of sequences have been d...

journal_title：Virology

authors： Simpson GR,Patience C,Löwer R,Tönjes RR,Moore HD,Weiss RA,Boyd MT

更新日期：1996-08-15 00:00:00

abstract：:HIV-1 infection leads to death of CD4(+) T cells in vivo and in vitro, although the mechanisms of this cell death are not well defined. We used flow cytometry to concurrently analyze infection and apoptosis of the CD4(+) CEM T cell line and human peripheral blood mononuclear cells (PBMC). Surprisingly, T cells product...

journal_title：Virology

authors： Rapaport E,Casella CR,Ikl,Mustafa F,Isaak D,Finkel TH

更新日期：1998-12-20 00:00:00