当前位置： SCI文献检索 > JOURNAL OF NEUROIMMUNOLOGY期刊下所有文献 > Suspected bacterial meningomyelitis: The first presenting clinical feature of neuromyelitis optica spectrum disorder.

Suspected bacterial meningomyelitis: The first presenting clinical feature of neuromyelitis optica spectrum disorder.

Abstract：

:A rare case of neuromyelitis optica spectrum disorder, suspected to be bacterial meningomyelitis as the initial manifestation, is reported. The patient presented with initial symptoms of meningomyelitis and fever. Cerebrospinal fluid analysis revealed pleocytosis (1280×106/L [98% lymphocytes]) and glucose level of 1.8mmol/L. Magnetic resonance imaging revealed >3 vertebral, longitudinally extensive transverse myelitis and area postrema lesions. Right optic neuritis was experienced 20months after the first attack. Serum anti-aquaporin-4 antibody was positive, and a diagnosis of neuromyelitis optica spectrum disorder was made, supporting the hypothesis that the pathogenesis of neuromyelitis optica is triggered by infection.

journal_name

J Neuroimmunol

journal_title

Journal of neuroimmunology

authors

Li X,Lin J,Pan S,Weng Y,Li J,Zhang X,Xia J,Tong Q

doi

10.1016/j.jneuroim.2017.05.013

subject

Has Abstract

pub_date

2017-08-15 00:00:00

pages

68-71

eissn

0165-5728

issn

1872-8421

pii

S0165-5728(17)30128-5

journal_volume

309

pub_type

杂志文章

相关文献

JOURNAL OF NEUROIMMUNOLOGY文献大全
  • HuR, a novel target of anti-Hu antibodies, is expressed in non-neural tissues.

    abstract：:Paraneoplastic encephalomyelitis (PEM) is characterized by a diverse set of clinical signs that are limited to the nervous system. The serologic hallmark of PEM is the presence of circulating autoantibodies, collectively referred to as 'anti-Hu,' which immunoreact specifically with members of the Elav protein family. ...

    journal_title：Journal of neuroimmunology

    pub_type： 杂志文章

    doi：10.1016/s0165-5728(98)00196-9

    authors： Nabors LB,Furneaux HM,King PH

    更新日期：1998-12-01 00:00:00

  • CD8+ high CD11b+ low T cells (T suppressor-effectors) in multiple sclerosis cerebrospinal fluid are increased during high dose corticosteroid treatment.

    abstract：:Using simultaneous dual direct immunofluorescence the effect of high dose intravenous methylprednisolone on the expression of T lymphocyte differentiation antigens in paired cerebrospinal fluid and peripheral blood samples of nine clinically active patients with multiple sclerosis was studied. Corticosteroid treatment...

    journal_title：Journal of neuroimmunology

    pub_type： 杂志文章

    doi：10.1016/0165-5728(91)90043-7

    authors： Durelli L,Poccardi G,Cavallo R

    更新日期：1991-03-01 00:00:00

  • Rat thymocytes release a factor which inhibits muscarinic ligand binding.

    abstract：:Rat thymocytes incubated in RPMI medium for 120-300 min release a soluble factor of molecular weight below 10,000 Da which inhibits the binding of 3H-labeled muscarinic antagonists in an uncompetitive manner, i.e. it reduces maximal specific binding (Bmax) without changing the affinity of the ligand (KD). This factor ...

    journal_title：Journal of neuroimmunology

    pub_type： 杂志文章

    doi：10.1016/0165-5728(88)90119-1

    authors： Maslinski W,Ryzewski J,Bartfai T

    更新日期：1988-03-01 00:00:00

  • The antibody response to oligodendrocyte specific protein in multiple sclerosis.

    abstract：:The role of autoantibody responses in pathogenesis or progression of multiple sclerosis (MS) remains controversial. This is partly because the methods that can distinctly identify pathogenic antibody reactivities targeting native membrane proteins from the reactivities that originate as an epiphenomenon in such diseas...

    journal_title：Journal of neuroimmunology

    pub_type： 杂志文章

    doi：10.1016/j.jneuroim.2010.02.008

    authors： Aslam M,Kalluri SR,Cepok S,Kraus V,Buck D,Srivastava R,Hemmer B

    更新日期：2010-04-15 00:00:00

  • Disturbed in vitro adrenergic modulation of cytokine production in inflammatory bowel diseases in remission.

    abstract：OBJECTIVE:Psychological stress has been implicated in the pathophysiology of both inflammatory and functional gastrointestinal (GI) diseases. The goal of this study was to address neuroendocrine modulation of cytokine production by peripheral blood cells in GI diseases. METHODS:We analyzed the in vitro effects of the ...

    journal_title：Journal of neuroimmunology

    pub_type： 杂志文章

    doi：10.1016/j.jneuroim.2006.09.011

    authors： Lucas A,Cobelens PM,Kavelaars A,Heijnen CJ,Holtmann G,Haag S,Gerken G,Langhorst J,Dobos GJ,Schedlowski M,Elsenbruch S

    更新日期：2007-01-01 00:00:00

  • Multiple sclerosis: death receptor expression and oligodendrocyte apoptosis in established lesions.

    abstract：:To determine whether TNF and TRAIL death receptors (DR), and decoy receptors (DcR), play a role in oligodendrocyte depletion in the lesions of chronic multiple sclerosis (MS), we investigated the presence and functionality of these molecules on oligodendrocytes in MS and non-MS brain tissue and on human oligodendrocyt...

    journal_title：Journal of neuroimmunology

    pub_type： 杂志文章

    doi：10.1016/j.jneuroim.2007.05.018

    authors： Cannella B,Gaupp S,Omari KM,Raine CS

    更新日期：2007-08-01 00:00:00

  • Targeting the B7/CD28:CTLA-4 costimulatory system in CNS autoimmune disease.

    abstract：:The B7/CD28:CTLA-4 costimulatory pathway plays a critical role in determining the fate of immune responses (activation vs. down-regulation) and is a highly promising therapeutic target for treating autoimmune diseases. In this review, we highlight the mechanisms by which this costimulatory pathway operates emphasizing...

    journal_title：Journal of neuroimmunology

    pub_type： 杂志文章,评审

    doi：10.1016/s0165-5728(98)00058-7

    authors： Karandikar NJ,Vanderlugt CL,Bluestone JA,Miller SD

    更新日期：1998-08-14 00:00:00

  • Soluble Fas (Apo-1) levels in cerebrospinal fluid of multiple sclerosis patients.

    abstract：:CSF and serum levels of soluble Fas were studied in MS patients, in patients with various neurological diseases and in healthy controls. We did not detect differences in serum sFas levels between MS patients and controls. In CSF, despite sFas levels being similar in all patients studied, a statistically significant co...

    journal_title：Journal of neuroimmunology

    pub_type： 杂志文章

    doi：10.1016/S0165-5728(97)00177-X

    authors： Ciusani E,Frigerio S,Gelati M,Corsini E,Dufour A,Nespolo A,La Mantia L,Milanese C,Massa G,Salmaggi A

    更新日期：1998-02-01 00:00:00

  • Exosomes from adipose-derived stem cells alleviate neural injury caused by microglia activation via suppressing NF-kB and MAPK pathway.

    abstract：:Activation of microglia cells play critical role in neuroinflammation after brain injury. Exosomes from adipose-derived stem cells (ADSC) possess immunoregulation effect similar with ADSC. We hypothesized that ADSC derived exosomes (ADSC-exosomes) could inhibit the activation of microglia cells and prevent neuroinflam...

    journal_title：Journal of neuroimmunology

    pub_type： 杂志文章

    doi：10.1016/j.jneuroim.2019.576996

    authors： Feng N,Jia Y,Huang X

    更新日期：2019-09-15 00:00:00

  • Tumour necrosis factor-alpha polymorphism and secretion in myasthenia gravis.

    abstract：:The mechanism behind the association between MHC genes and myasthenia gravis (MG) is not fully understood. In the present study we studied the associations with polymorphisms at HLA-DR3, HLA-B8 and TNF-alpha genes in Swedish patients and healthy individuals. The TNF-alpha-308 allele 2 was associated with female patien...

    journal_title：Journal of neuroimmunology

    pub_type： 杂志文章

    doi：10.1016/s0165-5728(98)00253-7

    authors： Huang DR,Pirskanen R,Matell G,Lefvert AK

    更新日期：1999-02-01 00:00:00

  • Adherence-mediated T cell activation in multiple sclerosis and other neurological disorders.

    abstract：:Peripheral blood T cells were isolated from chronic progressive multiple sclerosis patients using a stepwise protocol of density gradient centrifugation, erythrocyte rosetting and adherent cell depletion, after which T cells were cultured with no added stimulus. These cultures exhibited as much as 10-fold higher 'back...

    journal_title：Journal of neuroimmunology

    pub_type： 杂志文章

    doi：10.1016/0165-5728(94)90026-4

    authors： Kamin-Lewis RM,Karasanyi N,Koski CL,Lewis GK

    更新日期：1994-09-01 00:00:00

  • Interferon-beta specifically inhibits interferon-gamma-induced class II major histocompatibility complex gene transcription in a human astrocytoma cell line.

    abstract：:We established cultures of human astrocytes and astrocytoma cells from surgical specimens, to study regulation of class II major histocompatibility (MHC) complex antigen expression by interferons. Using these cultures we previously showed that expression of the class II MHC determinant HLA-DR could be induced by inter...

    journal_title：Journal of neuroimmunology

    pub_type： 杂志文章

    doi：10.1016/0165-5728(91)90054-b

    authors： Ransohoff RM,Devajyothi C,Estes ML,Babcock G,Rudick RA,Frohman EM,Barna BP

    更新日期：1991-08-01 00:00:00

  • Pathogenic and non-pathogenic T lymphocytes specific for the encephalitogenic epitope of myelin basic protein: functional characteristics and vaccination properties.

    abstract：:Activated CD4+ T lymphocytes specific for myelin basic protein (MBP) can cause experimental autoimmune encephalomyelitis (EAE) upon their inoculation into syngeneic recipients. In Lewis rats, most of the pathogenic T cell clones that develop following immunization with MBP are reactive against the 72-84 amino acid seq...

    journal_title：Journal of neuroimmunology

    pub_type： 杂志文章

    doi：10.1016/0165-5728(93)90283-5

    authors： Beraud E,Balzano C,Zamora AJ,Varriale S,Bernard D,Ben-Nun A

    更新日期：1993-08-01 00:00:00

  • ATP and adenosine induce ramification of microglia in vitro.

    abstract：:Microglial cells in the healthy adult brain possess a characteristic ramified morphology with multiple branched processes, small somata and down-regulated inflammatory properties. In contrast, microglial cells isolated from new-born rat brain inevitably show a non-ramified amoeboid phenotype, which is observed in vivo...

    journal_title：Journal of neuroimmunology

    pub_type： 杂志文章

    doi：10.1016/s0165-5728(01)00257-0

    authors： Wollmer MA,Lucius R,Wilms H,Held-Feindt J,Sievers J,Mentlein R

    更新日期：2001-04-02 00:00:00

  • Humoral immunity in the central nervous system of Lewis rats infected with Borna disease virus.

    abstract：:The aim of this study was to investigate the humoral immune response to Borna disease (BD) virus in the brain of experimentally infected Lewis rats. Abundant IgG was detected in BD-rat brain with isotype variation throughout infection. IgG was locally produced as indicated by an intact blood-brain barrier, Ig kappa li...

    journal_title：Journal of neuroimmunology

    pub_type： 杂志文章

    doi：10.1016/s0165-5728(98)00066-6

    authors： Hatalski CG,Hickey WF,Lipkin WI

    更新日期：1998-10-01 00:00:00

  • Inhibition of adenosine kinase attenuates inflammation and neurotoxicity in traumatic optic neuropathy.

    abstract：:Traumatic optic neuropathy (TON) is associated with apoptosis of retinal ganglion cells. Local productions of reactive oxygen species and inflammatory mediators from activated microglial cells have been hypothesized to underlie apoptotic processes. We previously demonstrated that the anti-inflammatory effect of adenos...

    journal_title：Journal of neuroimmunology

    pub_type： 杂志文章

    doi：10.1016/j.jneuroim.2014.10.006

    authors： Ahmad S,Elsherbiny NM,Bhatia K,Elsherbini AM,Fulzele S,Liou GI

    更新日期：2014-12-15 00:00:00

  • alpha-Tocopherol reduces lipopolysaccharide-induced peroxide radical formation and interleukin-6 secretion in primary murine microglia and in brain.

    abstract：:The purpose of this study was to determine if alpha-tocopherol-a reactive oxygen species (ROS) scavenging agent-inhibits LPS-induced oxidative stress and interleukin-6 (IL-6) production in murine microglia and brain. LPS increased intracellular peroxides and IL-6 in a dose-dependent fashion in primary microglia. The L...

    journal_title：Journal of neuroimmunology

    pub_type： 杂志文章

    doi：10.1016/j.jneuroim.2003.12.017

    authors： Godbout JP,Berg BM,Kelley KW,Johnson RW

    更新日期：2004-04-01 00:00:00

  • NGF modulates CGRP synthesis in human B-lymphocytes: a possible anti-inflammatory action of NGF?

    abstract：:We investigated whether the sensory neuropeptide, calcitonin gene-related peptide (CGRP), could be synthesised by human lymphocytes. Our results indicate that in activated B-cells, there is a strong expression of CGRP gene transcripts, which is almost absent in resting cells. Since B-cells autocrinally produce NGF, th...

    journal_title：Journal of neuroimmunology

    pub_type： 杂志文章

    doi：10.1016/s0165-5728(01)00475-1

    authors： Bracci-Laudiero L,Aloe L,Buanne P,Finn A,Stenfors C,Vigneti E,Theodorsson E,Lundeberg T

    更新日期：2002-02-01 00:00:00

  • TNFR1-dependent VCAM-1 expression by astrocytes exposes the CNS to destructive inflammation.

    abstract：:VCAM-1 is an adhesion molecule that is important to leukocyte movement across the blood-brain barrier and is involved in the formation of destructive CNS inflammatory lesions in experimental autoimmune encephalomyelitis (EAE) and multiple sclerosis (MS). We examined VCAM-1 expression in the CNS of animals with passive...

    journal_title：Journal of neuroimmunology

    pub_type： 杂志文章

    doi：10.1016/j.jneuroim.2004.02.012

    authors： Gimenez MA,Sim JE,Russell JH

    更新日期：2004-06-01 00:00:00

  • Impairment of electrophysiological function of astrocytes by cerebrospinal fluid from a patient with Waldenström's macroglobulinemia.

    abstract：:Patients with the Bing Neel type of Waldenström's macroglobulinemia often present with global neurological symptoms. In this case report, we investigated the effects of cerebrospinal fluid (CSF) of a such a patients (CSF-WM), who presented with seizures and psychomotor slowing, on the electrophysiological properties o...

    journal_title：Journal of neuroimmunology

    pub_type： 杂志文章

    doi：10.1016/0165-5728(95)00069-e

    authors： Köller H,von Giesen HJ,Siebler M

    更新日期：1995-08-01 00:00:00

  • Methylene blue alleviates experimental autoimmune encephalomyelitis by modulating AMPK/SIRT1 signaling pathway and Th17/Treg immune response.

    abstract：:Methylene blue (MB) is an effective neuroprotectant in many neurological disorders. AMP-activated protein kinase (AMPK)/silent mating-type information regulation 2 homolog 1 (SIRT1) plays a crucial role in maintaining inflammatory responses and shows a synergistic effect on cell homeostasis. We investigated the effect...

    journal_title：Journal of neuroimmunology

    pub_type： 杂志文章

    doi：10.1016/j.jneuroim.2016.08.014

    authors： Wang J,Zhao C,Kong P,Bian G,Sun Z,Sun Y,Guo L,Li B

    更新日期：2016-10-15 00:00:00

  • Epitope specificity and TCR V beta gene utilization in the encephalitogenic response of B10.RIII(71NS)/SnJ mice.

    abstract：:A high proportion of peptide 1-11 specific T cells from H-2u (V beta 8+, H-2u) mice express the V beta 8 TCR chain. Peptide 89-101 is immunodominant for B10.RIII (V beta 8+, H-2r) mice; thus, it was of interest to determine whether V beta 8 TCR would be over-represented in a population of peptide 89-101-specific T cel...

    journal_title：Journal of neuroimmunology

    pub_type： 杂志文章

    doi：10.1016/0165-5728(93)90012-n

    authors： Zhao ML,Xia JQ,Fritz RB

    更新日期：1993-02-01 00:00:00

  • Regulation of human B lymphocyte activation by opioid peptide hormones. Inhibition of IgG production by opioid receptor class (mu-, kappa-, and delta-) selective agonists.

    abstract：:Opioid peptides have been reported by many laboratories to modulate in vitro and in vivo cell-mediated and humoral immune responses. However, less attention has been afforded to the class or classes of opioid receptors involved in these immunomodulatory effects. Previous studies by this laboratory indicated that beta-...

    journal_title：Journal of neuroimmunology

    pub_type： 杂志文章

    doi：10.1016/0165-5728(95)00171-9

    authors： Morgan EL

    更新日期：1996-03-01 00:00:00

  • T-cell repertoire profiling by next-generation sequencing reveals tissue migration dynamics of TRBV13-family clonotypes in a common experimental autoimmune encephalomyelitis mouse model.

    abstract：:The experimental autoimmune encephalomyelitis (EAE) model is indispensable for autoimmunity research, but model-specific T cell dynamics are sparsely studied. We used next-generation immunosequencing across lymphoid organs, blood and spinal cord in response to immunization with myelin basic protein (MBP) to study T ce...

    journal_title：Journal of neuroimmunology

    pub_type： 杂志文章

    doi：10.1016/j.jneuroim.2019.03.014

    authors： Schliffke S,Carambia A,Akyüz N,Thiele B,Herkel J,Binder M

    更新日期：2019-07-15 00:00:00

  • Neurovascular fibrinolytic activity in normal Lewis rats and rats with cell-transferred experimental allergic encephalomyelitis.

    abstract：:Fibrinolytic activity in the form of plasminogen activator (PA) was assessed using a histochemical fibrin slide technique in spinal cords of normal Lewis rats and rats with the cell-transferred form of experimental allergic encephalomyelitis (EAE). PA was localized exclusively to blood vessels. Vessels in the leptomen...

    journal_title：Journal of neuroimmunology

    pub_type： 杂志文章

    doi：10.1016/0165-5728(90)90012-c

    authors： Koh CS,Kwaan HC,Paterson PY

    更新日期：1990-08-01 00:00:00

  • Platelet-activating factor acetylhydrolase gene polymorphism and its activity in Japanese patients with multiple sclerosis.

    abstract：:We evaluated the association of the plasma platelet-activating factor acetylhydrolase (PAF-AH) gene polymorphism (G(994)-->T) and PAF-AH activity with susceptibility and severity of multiple sclerosis (MS) in Japanese. DNA was collected from 216 patients with clinically definite MS (65 opticospinal MS (OS-MS) and 151 ...

    journal_title：Journal of neuroimmunology

    pub_type： 杂志文章

    doi：10.1016/j.jneuroim.2004.01.008

    authors： Osoegawa M,Niino M,Ochi H,Kikuchi S,Murai H,Fukazawa T,Minohara M,Tashiro K,Kira J

    更新日期：2004-05-01 00:00:00

  • Caveolin-3 is aberrantly expressed in skeletal muscle cells in myasthenia gravis.

    abstract：:Caveolin-3 is a muscle-specific membrane protein that localizes to the sarcolemma and T-tubule system. Caveolin-3 is needed for muscle repair and skeletal muscle development. The objective of this study was to compare caveolin-3 expression in myasthenia gravis (MG) and control muscles. Caveolin-3 was abnormally expres...

    journal_title：Journal of neuroimmunology

    pub_type： 杂志文章

    doi：10.1016/j.jneuroim.2016.10.011

    authors： Iwasa K,Furukawa Y,Yoshikawa H,Yamada M

    更新日期：2016-12-15 00:00:00

  • Antibodies to dendritic neuronal surface antigens in opsoclonus myoclonus ataxia syndrome.

    abstract：:Opsoclonus myoclonus ataxia syndrome (OMAS) is an autoimmune disorder characterized by rapid, random, conjugate eye movements (opsoclonus), myoclonus, and ataxia. Given these symptoms, autoantibodies targeting the cerebellum or brainstem could mediate the disease or be markers of autoimmunity. In a subset of patients ...

    journal_title：Journal of neuroimmunology

    pub_type： 杂志文章

    doi：10.1016/j.jneuroim.2015.07.007

    authors： Panzer JA,Anand R,Dalmau J,Lynch DR

    更新日期：2015-09-15 00:00:00

  • Selective uptake of multi-walled carbon nanotubes by tumor macrophages in a murine glioma model.

    abstract：:Carbon nantotubes (CNTs) are emerging as a new family of nanovectors for drug and gene delivery into biological systems. To evaluate potential application of this technology for brain tumor therapy, we studied uptake and toxicity of multi-walled CNTs (MWCNTs) in the GL261 murine intracranial glioma model. Within 24 h ...

    journal_title：Journal of neuroimmunology

    pub_type： 杂志文章

    doi：10.1016/j.jneuroim.2008.12.006

    authors： VanHandel M,Alizadeh D,Zhang L,Kateb B,Bronikowski M,Manohara H,Badie B

    更新日期：2009-03-31 00:00:00

  • Cultured astrocytes express regional heterogeneity of the immunoreactive phenotype under basal conditions and after gamma-IFN induction.

    abstract：:Cerebral astrocytes are known to show a region-specific phenotype, concerning the expression of several receptors and the synthesis of secreted substances. In order to find out whether this heterogeneity also exists for the immunological activation, we studied several parameters that are known to characterize activate...

    journal_title：Journal of neuroimmunology

    pub_type： 杂志文章

    doi：10.1016/s0165-5728(98)00099-x

    authors： Morga E,Faber C,Heuschling P

    更新日期：1998-07-01 00:00:00