Production of monodisperse silica gel microspheres for bioencapsulation by extrusion into an oil cross-flow.

abstract：:This work aimed to investigate the potential effect of cyclodextrin encapsulation on intrinsic ability of daidzein (DAD) and genistein (GEN) to inhibit the glycosaminoglycan (GAG) synthesis in fibroblasts originating from patients with mucopolysaccharidosis (MPS), type II and III. DAD or GEN encapsulation with either ...

journal_title：Journal of microencapsulation

authors： Fumić B,Jablan J,Cinčić D,Zovko Končić M,Jug M

更新日期：2018-01-01 00:00:00

abstract：:Polylactide (PLA) and polylactide-co-glycolide (PLGA) particles entrapping rotavirus (strain SA11) were formulated using a solvent evaporation technique. To minimize denaturation of viral antigen during the emulsification process, serum albumin was used as a stabilizer. Use of NaHCO(3) and sucrose during the primary e...

journal_title：Journal of microencapsulation

authors： Nayak B,Panda AK,Ray P,Ray AR

更新日期：2009-03-01 00:00:00

abstract：:Nanoparticles prepared of human serum albumin (HSA) represent promising carriers for drug delivery. Desolvating procedure is a common method to obtain protein-based particles. However process parameters have a great influence on size, size distribution and particle yield of the resulting formulation. Therefore, it is ...

journal_title：Journal of microencapsulation

authors： Storp Bv,Engel A,Boeker A,Ploeger M,Langer K

更新日期：2012-01-01 00:00:00

abstract：:The use of polymeric carriers in formulations of therapeutic drug delivery systems has gained widespread application, due to their advantage of being biodegradable and biocompatible. Among the microparticulate systems, microspheres have a special importance since it is possible to target drugs and provide controlled r...

journal_title：Journal of microencapsulation

authors： Tunçay M,Caliş S,Kaş HS,Ercan MT,Peksoy I,Hincal AA

更新日期：2000-03-01 00:00:00

abstract：:Redox-responsive magnetic protein microcapsules with Fe3O4 magnetic nanoparticles (MNPs) encapsulated inside have been obtained using a facile, cost-effective and fast sonochemical method from hen egg white proteins. Such prepared redox-responsive magnetic hen egg white protein microcapsules (MHEWPMCs) could be easily...

journal_title：Journal of microencapsulation

authors： Zhong S,Cui X,Tian F

更新日期：2015-01-01 00:00:00

abstract：:This study demonstrates the feasibility of using a single-capillary electrospray (ES) system to generate novel alpha-lipoic acid encapsulated poly(ethylene oxide)-chitosan (ALA/PEO/CS) particles with a monodispersed diameter. Scanning electron microscopic images (SEM) and dynamic light scattering (DLS) results indicat...

journal_title：Journal of microencapsulation

authors： Bai MY,Hu YM

更新日期：2014-01-01 00:00:00

abstract：:Phosphatidylcholine (from egg yolk)-cholesterol-stearylamine (7:2:2.25, molar ratio) liposomes when associated with cyclosporin A (phosphatidylcholine:cyclosporin A = 2:0.07, molar ratio) do not inhibit significantly the biosynthesis of [3H]polyglycerophosphatides and [3H]phosphatidylinositol in mitochondrial and micr...

journal_title：Journal of microencapsulation

authors： Stuhne-Sekalec L,Stanacev NZ

更新日期：1989-04-01 00:00:00

abstract：:This article describes the development of a freeze-dried formulation of chitosan (CS) nanocapsules containing docetaxel (DCX) and the evaluation of its efficacy in the NCI-H460 cancer cell line. More specifically, two prototypes of nanocapsules differing in their coating, CS alone or in combination with poloxamer 188 ...

journal_title：Journal of microencapsulation

authors： Lozano MV,Esteban H,Brea J,Loza MI,Torres D,Alonso MJ

更新日期：2013-01-01 00:00:00

abstract：:The formation of microcapsules which contain rosemary oil, is herewith described. The process is based on two steps: (a) formation of oil-in-water emulsions, by using lecithin as emulsifier, thus imparting negative charges on the oil droplets; (b) addition of a cationic biopolymer, chitosan, in conditions that favor t...

journal_title：Journal of microencapsulation

authors： Magdassi S,Bach U,Mumcuoglu KY

更新日期：1997-03-01 00:00:00

abstract：:In the previous report, microencapsulation of lipase employing a (w/o)/w multiple phase emulsion technique, with 2:1 polystyrene (PS)-SBR mixture being used as a wall material, was proposed. Catalysis of the encapsulated enzyme was investigated, and the hydrolysis of triacetin (triglyceride of acetic acid) was success...

journal_title：Journal of microencapsulation

authors： Iso M,Shirahase T,Hanamura S,Urushiyama S,Omi S

更新日期：1989-07-01 00:00:00

abstract：:The in vivo absorption of crystalline nitrofurantoin and the dosage forms of nitrofurantoin prepared with microcapsules were carried out in man by determination of urinary excretion of unchanged nitrofurantoin. The cumulative amount of drug excreted and the duration of the therapeutic urine levels were compared. The m...

journal_title：Journal of microencapsulation

authors： Ertan G,Karasulu E,Abou-Nada M,Tosun M,Ozer A

更新日期：1994-03-01 00:00:00

abstract：:Polyelectrolyte complexes (PEC) provide new opportunities for controlled release system of drugs, and have potentials to address challenges on the way to effective oral insulin delivery. Here, an innovative pH-sensitive PEC for insulin oral administration was developed, which was formed by self-assembly of two opposit...

journal_title：Journal of microencapsulation

authors： Chen T,Li S,Zhu W,Liang Z,Zeng Q

更新日期：2019-01-01 00:00:00

abstract：:Atomic force microscopy (AFM) is recognized a suitable and powerful technique for surface and morphological analysis. Even if until now this technique has not been frequently used in the pharmaceutical field, it can contribute to an accurate morphologic characterization of microspheres and nanospheres. In this work, a...

journal_title：Journal of microencapsulation

authors： Dorati R,Patrini M,Perugini P,Pavanetto F,Stella A,Modena T,Genta I,Conti B

更新日期：2006-03-01 00:00:00

abstract：:Polyurethane modified with polylactic acid microcapsules were fabricated for controlled release of chlorpyrifos (one of the high usage solid phosphorous insecticides) via interfacial polymerisation with diphenylmethane diisocyanate, polyether triol, 1,4-butanediol and polylactic acid as modifier. The structure, morpho...

journal_title：Journal of microencapsulation

authors： Zheng T,Chen K,Chen W,Wu B,Sheng Y,Xiao Y

更新日期：2019-01-01 00:00:00

abstract：:Background: Lavender oil consists of around 100 components and is susceptible to volatilisation and degradation reactions. Aim: Microencapsulate lavender oil by spray drying using a biocompatible polymeric blend of gum acacia and maltodextrin to protect the oil components. Effect of total polymer content, oil loading,...

journal_title：Journal of microencapsulation

authors： Burhan AM,Abdel-Hamid SM,Soliman ME,Sammour OA

更新日期：2019-05-01 00:00:00

abstract：:We demonstrate the microencapsulation of a double-base (DB) rocket propellant stabiliser, 2-nitrodiphenylamine (2-NDPA), that can potentially increase the shelf life of DB rocket propellants. Poly(lactide-co-glycolide) (PLG) microspheres loaded with 2-NDPA were prepared using the oil-in-water emulsion technique. The m...

journal_title：Journal of microencapsulation

authors： Shorty M,Singh S,Jebrail FF,Andrews MJ

更新日期：2012-01-01 00:00:00

abstract：:Sub-100-nm nanoparticles were prepared from beta-lactoglobulin (BLG) with a narrow size distribution by a desolvation method using glutaraldehyde for cross-linking. With pre-heating of the BLG solution to 60 degrees C and subsequent pH readjustment to 9.0, nanoparticles of 59 +/- 5 nm were obtained with improved unifo...

journal_title：Journal of microencapsulation

authors： Ko S,Gunasekaran S

更新日期：2006-12-01 00:00:00

abstract：:A biocompatible emulsification method has been developed for microencapsulation of live cells and enzymes within a calcium alginate matrix. Fabrication of alginate beads was achieved by premixing a sequestering agent (sodium polyphosphate) and the calcium source (calcium sulphate) with the hydrogel monomer prior to th...

journal_title：Journal of microencapsulation

authors： Monshipouri M,Price RR

更新日期：1995-05-01 00:00:00

abstract：:Transplantation of cells genetically modified to produce neurotrophins is a promising spinal cord repair strategy. Previously we showed that fibroblasts engineered to produce brain-derived neurotrophic factor (Fb/BDNF) microencapsulated in alginate survive, continue to grow and express bioactive BDNF. We here compared...

journal_title：Journal of microencapsulation

authors： Francis NL,Shanbhag MS,Fischer I,Wheatley MA

更新日期：2011-01-01 00:00:00

abstract：:The aim of the present study is to construct a type of polyion complex micelles made of PF127-PEI copolymer and cholic acid (CA) and to evaluate the potential of this type of micelles as a targeted drug delivery system for paclitaxel (PTX). To further improve the targeting capability of micelles, folate was also incor...

journal_title：Journal of microencapsulation

authors： Li Y,Zhou Y,De B,Li L

更新日期：2014-01-01 00:00:00

abstract：:An overview of biodegradable and biocompatible microcapsules and microspheres loaded with neuroactive substances, or cells producing neuroactive substances, and their role as drug delivery systems (DDS) for drug administration to the central nervous system (CNS) is given. In addition, closely related systems are also ...

journal_title：Journal of microencapsulation

authors： Filipović-Grcić J,Maysinger D,Jalsenjak I

更新日期：1995-07-01 00:00:00

abstract：:Using formalin inactivated Actinobacillus pleuropneumoniae antigens and aqueous ethylcellulose dispersions, microspheres of oral vaccines were developed by a co-spray drying process. The present study attempted to determine whether the dosage formulations of microspheres could form enteric matrices. To assess the ente...

journal_title：Journal of microencapsulation

authors： Liao CW,Cheng IC,Yeh KS,Lin FY,Weng CN

更新日期：2001-05-01 00:00:00

abstract：:Sequential interpenetrating networks of poly(methacrylic acid) and poly(vinyl alcohol) have been prepared and cross-linked with glutaraldehyde to obtain pH sensitive microspheres by a water-in-oil emulsification method. Microspheres have been used to deliver the chosen model anti-inflammatory drug viz., ibuprofen to t...

journal_title：Journal of microencapsulation

authors： Mundargi RC,Patil SA,Kulkarni PV,Mallikarjuna NN,Aminabhavi TM

更新日期：2008-06-01 00:00:00

abstract：:Radioembolization is used in diagnostic imaging of the lungs and for radioembolization therapy of hepatic tumours. Presently, 99mTc labelled macroaggregates or microspheres of human serum albumin (HAM) are used for this purpose. Poly lactic acid (PLA) is biodegradable, like HAM, and, unlike HAM, is not a blood product...

journal_title：Journal of microencapsulation

authors： Ergün EL,Ercan MT,Selek H,Kaş HS,Ruacan S,Unsal IS,Mutlu M

更新日期：2000-07-01 00:00:00

abstract：:Palmatine (PM) is a potent anti-infective agent used to treat eye diseases. However, PM is less effective for ocular application due to short residence time within the eyes. This study aimed to develop a cationic lipid emulsions (CLEs) for ophthalmic delivery of PM and evaluate its suitability in infection treatment. ...

journal_title：Journal of microencapsulation

authors： Yin J,Xiang C,Lu G

更新日期：2016-12-01 00:00:00

abstract：:The sustained delivery of multiple agents to the lung offers potential benefits to patients. This study explores the preparation of highly respirable dual-loaded spray-dried double emulsions. Spray-dried powders were produced from water-in-oil-in-water (w/o/w) double emulsions, containing salbutamol sulphate and/or be...

journal_title：Journal of microencapsulation

authors： Learoyd TP,Burrows JL,French E,Seville PC

更新日期：2010-01-01 00:00:00

abstract：:The diblock copolymers based on PBLG and PEO (GE) were synthesized and characterized. Nanoparticles showed spherical shape from the observations of TEM and approved core-shell structure. Drug contents were increased with use of higher initial drug concentration and higher Mw of GE. Nifedipine (NFD) release rate was sl...

journal_title：Journal of microencapsulation

authors： Jeong YI,Sun HS,Shim YH,Kim C,Park SH,Choi KC,Cho CS

更新日期：2004-06-01 00:00:00

abstract：:Documented to exhibit cytotoxicity and poor oral bioavailability, alpha-mangostin was encapsulated into PLGA microspheres with optimization of formulation using response surface methodology. Mixed levels of four factors Face central composite design was employed to evaluate critical formulation variables. With 30 runs...

journal_title：Journal of microencapsulation

authors： Elsaid Ali AA,Taher M,Mohamed F

更新日期：2013-01-01 00:00:00

abstract：:The aim of this study was to formulate, characterise and evaluate the activity of amodiaquine microparticles against Leishmania donovani. Microparticles were formulated by encapsulating the drug in bovine serum albumin using the spray-dryer method. The microparticles were evaluated for size, zeta potential, drug conte...

journal_title：Journal of microencapsulation

authors： Nettey H,Allotey-Babington GL,Somuah I,Banga NB,Afrane B,Amponsah SK,Annor H,Darko H,Hanson K,Aidoo A,Broni MN,Sasu C,Nyarko A

更新日期：2017-02-01 00:00:00

abstract：:The effect of process variables such as nozzle size, flow-rate of dispersed phase, inter-electrode distance, and presence of an acid acceptor and a thickening agent in the dispersed phase, on the production and size distribution of nylon 6-10 microcapsules prepared by interfacial polymerization in a high-voltage elect...

journal_title：Journal of microencapsulation

authors： Etuk BR,Weatherley LR,Murray KR

更新日期：1995-03-01 00:00:00