Abstract:
:We demonstrate the microencapsulation of a double-base (DB) rocket propellant stabiliser, 2-nitrodiphenylamine (2-NDPA), that can potentially increase the shelf life of DB rocket propellants. Poly(lactide-co-glycolide) (PLG) microspheres loaded with 2-NDPA were prepared using the oil-in-water emulsion technique. The microsphere size was found to be inversely related to the mixing rate. It was also found that a higher theoretical loading of 2-NDPA resulted in larger microspheres. In addition, a Rosin Rammler distribution function gave an accurate representation of the microsphere size distribution, and the release rate 2-NDPA from PLG microspheres was found to be size dependent. We show that parameters such as the stirring speed and the percent loading of 2-NDPA can be varied to tailor the release of 2-NDPA from PLG microspheres. In addition, we have shown that temperature has a dramatic effect on the release of 2-NDPA from PLG microcapsules.
journal_name
J Microencapsuljournal_title
Journal of microencapsulationauthors
Shorty M,Singh S,Jebrail FF,Andrews MJdoi
10.3109/02652048.2012.668956subject
Has Abstractpub_date
2012-01-01 00:00:00pages
569-75issue
6eissn
0265-2048issn
1464-5246journal_volume
29pub_type
杂志文章abstract::Liposomes are known to be a potent adjuvant for a wide range of antigens, as well as appropriate antigen carriers for antibody generation response in vivo. In addition, liposomes are effective vehicles for peptides and proteins, thus enhancing their immunogenicity. Considering these properties of liposomes and the ant...
journal_title:Journal of microencapsulation
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journal_title:Journal of microencapsulation
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abstract::The chitosan microspheres were prepared by a membrane emulsification method with variations of the N2 gas pressure and the chitosan concentration. The pressure of N2 gas was varied within the range from 0.2 x 10(5) to 0.8 x 10(5) Pa at chitosan concentration 1.5 wt%. In addition, the concentration of chitosan was vari...
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journal_title:Journal of microencapsulation
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journal_title:Journal of microencapsulation
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journal_title:Journal of microencapsulation
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journal_title:Journal of microencapsulation
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journal_title:Journal of microencapsulation
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