Microencapsulation of drugs by the coacervation technique using ethylcellulose and acrylate-methacrylate copolymer as wall materials.

abstract：:PLA microparticles containing 17-β-estradiol valerate were prepared by an emulsion/evaporation method in order to sustain drug release. This system was characterized concerning particle size, particle morphology and the influence of formulation and processing parameters on drug encapsulation and in vitro drug release....

journal_title：Journal of microencapsulation

authors： Machado SR,Lunardi LO,Tristão AP,Marchetti JM

更新日期：2009-05-01 00:00:00

abstract：:Microspheres, including microcapsules and cells or beads, are widely used to produce many functional products. Information about their mechanical properties is essential to understanding their performance during manufacturing, processing and end-use applications. The mechanical characterization of microspheres require...

journal_title：Journal of microencapsulation

authors： Mercadé-Prieto R,Zhang Z

更新日期：2012-01-01 00:00:00

abstract：:Ionotropic gelation was used to entrap sulindac into calcium alginate beads as a potential drug carrier for the oral delivery of this anti-inflammatory drug. Beads were investigated in vitro for a possible sustained drug release and their use in vivo as a gastroprotective system for sulindac. Process parameters such a...

journal_title：Journal of microencapsulation

authors： Yegin BA,Moulari B,Durlu-Kandilci NT,Korkusuz P,Pellequer Y,Lamprecht A

更新日期：2007-06-01 00:00:00

abstract：:Liposomes were introduced first in 1980 for topical drug delivery and since then have attracted considerable interest and generated many speculative claims concerning their potential utility both as a drug carrier and reservoir for controlled release of drugs within various layers of the skin. A number of clinical stu...

journal_title：Journal of microencapsulation

authors： Moghimi SM,Patel HM

更新日期：1993-04-01 00:00:00

abstract：:Provision and maintenance of adequate concentrations of antibiotics at infection sites is very important in treating highly resistant infections. For diseases like implant related osteomyelitis (IRO) it is best to provide this locally via implanted drug formulations, as systemic administration of the antibiotic may no...

journal_title：Journal of microencapsulation

authors： Gurselt I,Yagmurlu F,Korkusuz F,Hasirci V

更新日期：2002-03-01 00:00:00

abstract：:Optimum conditions for the preparation of non-magnetic and magnetic microspheres of albumin-globulin mix (alglomix) containing mefenamic acid have been standardized. The effect of various parameters has been investigated with regard to the appearance, yield, drug content and encapsulation efficiency. The physicochemic...

journal_title：Journal of microencapsulation

authors： Lalla JK,Ahuja PL

更新日期：1991-01-01 00:00:00

abstract：:This paper describes a novel approach to prepare and characterize calcium-shellac spheres as a carrier of a tooth whitening agent carbamide peroxide. Calcium-shellac spheres were prepared using an extrusion technique based on dropping aqueous ammonium shellac solution into calcium chloride solution. The effects of for...

journal_title：Journal of microencapsulation

authors： Xue J,Zhang Z

更新日期：2008-12-01 00:00:00

abstract：:For the preparation of microcapsules using the W/O/W (water in oil in water) emulsion system, it is essential to control various factors such as the dispersed state of the organic phase in the W/O/W emulsion, the difference in the solute concentration between the inner and outer aqueous phases and the volume fraction ...

journal_title：Journal of microencapsulation

authors： Kiyoyama S,Shiomori K,Kawano Y,Hatate Y

更新日期：2003-07-01 00:00:00

abstract：:The present study describes the development of a new cyclosporine formulation based on polycaprolactone (PCL) microspheres (MS) prepared by the solvent evaporation method. Ternary phase diagrams were used to identify the domains where MS were formed. The application of central composite designs established the influen...

journal_title：Journal of microencapsulation

authors： Aberturas MR,Molpeceres J,Guzmán M,García F

更新日期：2002-01-01 00:00:00

abstract：:Sequential interpenetrating networks of poly(methacrylic acid) and poly(vinyl alcohol) have been prepared and cross-linked with glutaraldehyde to obtain pH sensitive microspheres by a water-in-oil emulsification method. Microspheres have been used to deliver the chosen model anti-inflammatory drug viz., ibuprofen to t...

journal_title：Journal of microencapsulation

authors： Mundargi RC,Patil SA,Kulkarni PV,Mallikarjuna NN,Aminabhavi TM

更新日期：2008-06-01 00:00:00

abstract：:Freeze-drying is an effective way to improve long-term physical stability of nanosuspension in drug delivery applications. Nanosuspension also known as suspension of nanoparticles. In this study, the effect of freeze-drying with different cryoprotectants on the physicochemical characteristics of resveratrol (RSV) nano...

journal_title：Journal of microencapsulation

authors： Wang L,Ma Y,Gu Y,Liu Y,Zhao J,Yan B,Wang Y

更新日期：2018-05-01 00:00:00

abstract：:This paper prepared novel biodegradable and pH-sensitive microgels based on Poly(epsilon-caprolactone)-Pluronic-Poly(epsilon-caprolactone)-dimethacrylate (PCFC-DMA), Poly(ethylene glycol) dimethacrylate (PEG-DMA) and methylacrylic acid (MAA) cross-linked with N,N'-methylenebisacrylamide (BIS), initiated by NaHSO(3), K...

journal_title：Journal of microencapsulation

authors： Xu X,Fu S,Wang K,Jia W,Guo G,Zheng X,Dong P,Guo Q,Qian Z

更新日期：2009-11-01 00:00:00

abstract：AIM:To study the effect of poly(d,l-lactic-co-glycolic acid) (PLGA) microparticles (MPs) preparation techniques on particle physical characterization with special emphasis on burst drug release. METHODS:A basic drug clozapine was used in combination with acid-terminated PLGA. Two approaches for MP preparation were com...

journal_title：Journal of microencapsulation

authors： Ishak RA,Mortada ND,Zaki NM,El-Shamy Ael-H,Awad GA

更新日期：2014-01-01 00:00:00

abstract：:Polyisohexylcyanoacrylate nanocapsules containing cyclosporin were prepared by mixing in a 1:2 ratio an oil/ethanol solution of monomer and drug with an aqueous phase. Drug nanoencapsulation rate was controlled by its partition coefficient between the inner (organic) and outer (aqueous) phases. Thus highest encapsulat...

journal_title：Journal of microencapsulation

authors： Bonduelle S,Foucher C,Leroux JC,Chouinard F,Cadieux C,Lenaerts V

更新日期：1992-04-01 00:00:00

abstract：:Ibuprofen-loaded polystyrene microparticles were prepared by the emulsion-solvent evaporation process from an aqueous system. The effects of different parameters on the drug content and on the release of the drug from the microparticles were investigated. The drug content, in all the formulations, was less than the th...

journal_title：Journal of microencapsulation

authors： Tamilvanan S,Sa B

更新日期：2000-01-01 00:00:00

abstract：:In this study microspheres of diclofenac sodium, an anti-inflammatory agent, were prepared by utilizing a natural polysaccharide, chitosan-H. The objective of this investigation was to sustain the action of diclofenac sodium and to show the effect of various conditions on release kinetics. For this reason factorial de...

journal_title：Journal of microencapsulation

authors： Açikgöz M,Kaş HS,Orman M,Hincal AA

更新日期：1996-03-01 00:00:00

abstract：:The microencapsulation of drugs is gaining importance in many research activities. A common technique for preparing microcapsules is the solvent evaporation method which is simple but has a large number of reaction control parameters. This study reports the microcapsulation of allopurinol by the solvent evaporation me...

journal_title：Journal of microencapsulation

authors： Arabi H,Hashemi SA,Fooladi M

更新日期：1996-09-01 00:00:00

abstract：:We studied a model system of controlled drug release using beta-carotene and κ-carrageenan/NaCMC hydrogel as a drug and a device, respectively. Different concentrations of genipin were added to crosslink the beta-carotene loaded beads by using the dripping method. Results have shown that the cross-linked beads possess...

journal_title：Journal of microencapsulation

authors： Hezaveh H,Muhamad II,Noshadi I,Shu Fen L,Ngadi N

更新日期：2012-01-01 00:00:00

abstract：:The aim was to study the effect of the type of polymer solvent on characteristics of microspheres produced by spray drying. The water-soluble model protein, bovine serum albumin (BSA) was microencapsulated into biodegradable poly(D,L-lactic acid) using the following 10 different polymer solvents: acetaldehyde dimethyl...

journal_title：Journal of microencapsulation

authors： Gander B,Wehrli E,Alder R,Merkle HP

更新日期：1995-01-01 00:00:00

abstract：:H-n.m.r. spectroscopy of small unilamellar phospholipid vesicles in the presence of the lanthanide probe ion Dy3+ has been used to study the permeability of these liposomes induced by the bile salts (glycocholate and glycodeoxycholate) and pancreatic phospholipase A2. A marked synergism is demonstrated in the combined...

journal_title：Journal of microencapsulation

authors： Hunt GR,Jones IC

更新日期：1984-04-01 00:00:00

abstract：:The objective of this study was to prepare floating theophylline microspheres with zero order release profiles for use as buoyant reservoirs with increased retention time in the stomach. The microspheres were prepared by a modified emulsion-solvent evaporation method using a polymer mixture of cellulose acetate butyra...

journal_title：Journal of microencapsulation

authors： Stithit S,Chen W,Price JC

更新日期：1998-11-01 00:00:00

abstract：:To overcome the recurrence problem in bladder tumours; nanoparticles with positive surface charge may improve interaction with biological membranes for intravesical administration. The aim of this study was to design, develop and evaluate (in vitro-in vivo) cationic nanoparticles based on chitosan, poly-L-lysine or po...

journal_title：Journal of microencapsulation

authors： Erdoğar N,Iskit AB,Mungan NA,Bilensoy E

更新日期：2012-01-01 00:00:00

abstract：:Radioembolization is used in diagnostic imaging of the lungs and for radioembolization therapy of hepatic tumours. Presently, 99mTc labelled macroaggregates or microspheres of human serum albumin (HAM) are used for this purpose. Poly lactic acid (PLA) is biodegradable, like HAM, and, unlike HAM, is not a blood product...

journal_title：Journal of microencapsulation

authors： Ergün EL,Ercan MT,Selek H,Kaş HS,Ruacan S,Unsal IS,Mutlu M

更新日期：2000-07-01 00:00:00

abstract：:The physical entrapment of a hydrophilic drug within degradable microspheres is generally difficult because of poor entrapment yield and/or fast release, depending on the microsphere fabrication method. In order to counter the effects of drug hydrophilicity, it is proposed to covalently attach the drug to lactic acid ...

journal_title：Journal of microencapsulation

authors： Ustariz-Peyret C,Coudane J,Vert M,Kaltsatos V,Boisramené B

更新日期：2000-09-01 00:00:00

abstract：:Liposomes are known to be a potent adjuvant for a wide range of antigens, as well as appropriate antigen carriers for antibody generation response in vivo. In addition, liposomes are effective vehicles for peptides and proteins, thus enhancing their immunogenicity. Considering these properties of liposomes and the ant...

journal_title：Journal of microencapsulation

authors： Colhone MC,Silva-Jardim I,Stabeli RG,Ciancaglini P

更新日期：2015-01-01 00:00:00

abstract：:This study optimized and evaluated the conditions for surface coating of microspheres using a spray-dryer. Four formulations of Bromophenol blue (BPB)-loaded albumin microspheres were prepared using a spray-dryer, cross-linked at different concentrations and time periods. One of the optimized formulations with the des...

journal_title：Journal of microencapsulation

authors： Bejugam NK,Uddin AN,Gayakwad SG,D'Souza MJ

更新日期：2008-12-01 00:00:00

abstract：:Indomethacin micro-crystals sized approximately 2 microm have been encapsulated with polyelectrolyte multi-layers for the purpose of controlled release. Charged linear poly (dimethyldiallyl ammonium chloride) (PDDA) and poly (styrene sulphonate) (PSS) were alternatively deposited on approximately 2 microm drug micro-c...

journal_title：Journal of microencapsulation

authors： Chen Y,Lin X

更新日期：2005-02-01 00:00:00

abstract：:Chronic osteomyelitis is still the cause of many problems in orthopaedics in terms of therapy and infection persistence. Four-to-six week systemic antibiotic therapy is required along with bone and soft tissue debridement in the therapy of chronic osteomyelitis. Prolonged-release local antibiotic therapy has been take...

journal_title：Journal of microencapsulation

authors： Yenice I,Caliş S,Atilla B,Kaş HS,Ozalp M,Ekizoğlu M,Bilgili H,Hincal AA

更新日期：2003-11-01 00:00:00

abstract：:The formation of microcapsules which contain rosemary oil, is herewith described. The process is based on two steps: (a) formation of oil-in-water emulsions, by using lecithin as emulsifier, thus imparting negative charges on the oil droplets; (b) addition of a cationic biopolymer, chitosan, in conditions that favor t...

journal_title：Journal of microencapsulation

authors： Magdassi S,Bach U,Mumcuoglu KY

更新日期：1997-03-01 00:00:00

abstract：:Microencapsulation of ketoprofen using Eudragit RS and RL (acrylic resins) was investigated based on the dispersion system of ketoprofen-containing acetone in liquid paraffin. Aluminium tristearate was used as an additive for the preparation of microcapsules. Good reproducibility was observed in the microencapsulation...

journal_title：Journal of microencapsulation

authors： Goto S,Kawata M,Nakamura M,Maekawa K,Aoyama T

更新日期：1986-10-01 00:00:00