Preparation of polyurea/melamine formaldehyde double-layered self-healing microcapsules and investigation on core fraction.

Abstract:

:Moisture curing type self-healing microcapsules become more attractive, while instability of active core material crippled the efficiency of self-healing behaviour. Polyurea (PU)/melamine formaldehyde (MF) double-layered self-healing microcapsules containing isophorone diisocyanate (IPDI) core with high and stable core fraction were prepared. The structure, morphology, particle size and distribution were studied with Fourier transform infra-red spectroscopy, optical microscopy, scanning electron microscopy and Mastersizer 3000. The influences of process conditions were investigated to uncover the principle of core fraction and morphology of microcapsules. The core fraction of microcapsules was reduced with the increase of ageing time, and microcapsules prepared with ice-bath, polyetheramine (PEA) and prepolymer of melamine formaldehyde (P-MF) had higher core fraction and better morphology. PEA D230 and 1500 rpm agitation rate were chosen according to optimised trade-offs in the core fraction and morphology of the microcapsules.

journal_name

J Microencapsul

authors

Ming Y,Hu J,Xing J,Wu M,Qu J

doi

10.1080/02652048.2016.1178352

subject

Has Abstract

pub_date

2016-06-01 00:00:00

pages

307-14

issue

4

eissn

0265-2048

issn

1464-5246

journal_volume

33

pub_type

杂志文章
  • Potential antioxidant and anti-inflammatory action of Hypericum hookerianum extracts in a liposome system evaluated with zebrafish embryos.

    abstract::The purpose of this study was to assess the antioxidant and anti-inflammatory potential of liposomal formulations enriched with Hypericum hookerianum (Hyp) aqueous extracts. Cotyledon segments derived from protocorms of H. hookerianum were cultured on Murashige and Skoog (MS) media supplemented with Kinetin (KN, 1 mgl...

    journal_title:Journal of microencapsulation

    pub_type: 杂志文章

    doi:10.1080/02652048.2019.1631400

    authors: Pradeep PS,Manisha S,Monica Amala Nayaki J,Sivaraman D,Selvaraj R,Seeni S

    更新日期:2019-09-01 00:00:00

  • Diclofenac sodium loaded-cellulose acetate butyrate: effect of processing variables on microparticles properties, drug release kinetics and ulcerogenic activity.

    abstract::The aim of this study was to develop and characterize diclofenac sodium loaded-cellulose acetate butyrate microparticles in order to obtain a controlled-release system. The influence of the type of polymer, the volume and composition of the internal phase, drug loading, surfactant concentration and additive added on m...

    journal_title:Journal of microencapsulation

    pub_type: 杂志文章

    doi:10.1080/02652040701747928

    authors: Barakat NS,Ahmad AA

    更新日期:2008-02-01 00:00:00

  • The action of Triton X-100 and sodium dodecyl sulphate on lipid layers. Effect on monolayers and liposomes.

    abstract::The action of two detergents, Triton X-100 and sodium dodecyl sulphate (SDS), on large, unilamellar liposomes was determined as liposome size variation, polydispersity and ability to release a soluble marker from liposomes. Triton X-100 produced stronger effects than SDS. Nevertheless, these differences in behaviour o...

    journal_title:Journal of microencapsulation

    pub_type: 杂志文章

    doi:10.3109/02652049009021838

    authors: Hernández-Borrell J,Pons M,Juarez JC,Estelrich J

    更新日期:1990-04-01 00:00:00

  • Self-assembled micelles based on gambogenic acid-phospholipid complex for sustained-release drug delivery.

    abstract::Objective: To improve the water solubility and enhance the oral bioavailability of gambogenic acid (GNA). Methods: GNA-phospholipid complex (GNA-PLC) micelles were successfully prepared by anti-solvent method. Results: The encapsulation efficiency of GNA-PLC micelles can reach 99.33 % (w/w). The average particle size ...

    journal_title:Journal of microencapsulation

    pub_type: 杂志文章

    doi:10.1080/02652048.2019.1656294

    authors: Wang B,Cheng W,Zhang C,Bao Y,Zha L,Qian J,Hong L,Chen W

    更新日期:2019-09-01 00:00:00

  • Preparation and characterization of liposome-encapsulated haemoglobin by a freeze-thaw method.

    abstract::Haemoglobin (Hb) was encapsulated into liposomes as a blood substitute by a freeze-thaw method. The encapsulation efficiency was affected by the Hb/lipid ratio, starting Hb concentration, pH and salt concentration. Liposome-encapsulated haemoglobin (LEH) prepared by this method contains 5-10 mM Hb with 4-10 per cent m...

    journal_title:Journal of microencapsulation

    pub_type: 杂志文章

    doi:10.3109/02652049409034258

    authors: Liu L,Yonetani T

    更新日期:1994-07-01 00:00:00

  • Effect of surfactant HLB and different formulation variables on the properties of poly-D,L-lactide microspheres of naltrexone prepared by double emulsion technique.

    abstract::The aim of this work was to investigate the role of HLB of emulsifier as well as volume of the internal aqueous phase (W(1)) and presence of salt in the external aqueous phase (W(2)) on the morphology, size and encapsulation efficiency of poly(D,L-lactide) microspheres containing naltrexone HCl. PLA microparticles con...

    journal_title:Journal of microencapsulation

    pub_type: 杂志文章

    doi:10.1080/02652040400026392

    authors: Dinarvand R,Moghadam SH,Sheikhi A,Atyabi F

    更新日期:2005-03-01 00:00:00

  • Influence of alginate cross-linking method on neurite response to microencapsulated neurotrophin-producing fibroblasts.

    abstract::Transplantation of cells genetically modified to produce neurotrophins is a promising spinal cord repair strategy. Previously we showed that fibroblasts engineered to produce brain-derived neurotrophic factor (Fb/BDNF) microencapsulated in alginate survive, continue to grow and express bioactive BDNF. We here compared...

    journal_title:Journal of microencapsulation

    pub_type: 杂志文章

    doi:10.3109/02652048.2011.569765

    authors: Francis NL,Shanbhag MS,Fischer I,Wheatley MA

    更新日期:2011-01-01 00:00:00

  • Preparation and evaluation of PLGA microparticles as carrier for the pulmonary delivery of rhIL-2 : I. Effects of some formulation parameters on microparticle characteristics.

    abstract::In this study, recombinant human interleukin-2 (rhIL-2) containing poly(lactic-co-glycolic acid) (PLGA) microparticles were prepared for pulmonary administration by modified w/o/w double emulsion solvent extraction method and the effects of various formulation parameters on the physicochemical properties of the microp...

    journal_title:Journal of microencapsulation

    pub_type: 杂志文章

    doi:10.3109/02652048.2011.599438

    authors: Devrim B,Bozkir A,Canefe K

    更新日期:2011-01-01 00:00:00

  • Studies on the in vitro release characteristics of ibuprofen-loaded polystyrene microparticles.

    abstract::Ibuprofen-loaded polystyrene microparticles were prepared by the emulsion-solvent evaporation process from an aqueous system. The effects of different parameters on the drug content and on the release of the drug from the microparticles were investigated. The drug content, in all the formulations, was less than the th...

    journal_title:Journal of microencapsulation

    pub_type: 杂志文章

    doi:10.1080/026520400288553

    authors: Tamilvanan S,Sa B

    更新日期:2000-01-01 00:00:00

  • In vitro antibiotic release from poly(3-hydroxybutyrate-co-3-hydroxyvalerate) rods.

    abstract::Provision and maintenance of adequate concentrations of antibiotics at infection sites is very important in treating highly resistant infections. For diseases like implant related osteomyelitis (IRO) it is best to provide this locally via implanted drug formulations, as systemic administration of the antibiotic may no...

    journal_title:Journal of microencapsulation

    pub_type: 杂志文章

    doi:10.1080/02652040110065413

    authors: Gurselt I,Yagmurlu F,Korkusuz F,Hasirci V

    更新日期:2002-03-01 00:00:00

  • Electrophoretic ink using urea-formaldehyde microspheres.

    abstract::A kind of electronic ink, which is supported on indium-tin-oxide (ITO) glass before polymerization, is prepared using urea and formaldehyde resin as wall materials, in which TiO(2) modified with PMMA are dispersed in tetrachloroethylene (TCE) using a mixture of oil blue dyes and charge control additive (span80). Rotar...

    journal_title:Journal of microencapsulation

    pub_type: 杂志文章

    doi:10.1080/02652040600788197

    authors: Wang YT,Zhao XP,Wang DW

    更新日期:2006-11-01 00:00:00

  • Encapsulation of Sesbania grandiflora extract in polymeric micelles to enhance its solubility, stability, and antibacterial activity.

    abstract::Clinical applications of Sesbania grandiflora bark extract (SGE) are limited because of its poor water solubility and stability. SGE was loaded in micelles of Pluronics. In vitro and in vivo antibacterial and toxicity tests were investigated using broth dilution and silkworm model. Aqueous solubility of SGE was improv...

    journal_title:Journal of microencapsulation

    pub_type: 杂志文章

    doi:10.1080/02652048.2017.1284277

    authors: Anantaworasakul P,Okonogi S

    更新日期:2017-02-01 00:00:00

  • Formulation, characterization and evaluation of rotavirus encapsulated PLA and PLGA particles for oral vaccination.

    abstract::Polylactide (PLA) and polylactide-co-glycolide (PLGA) particles entrapping rotavirus (strain SA11) were formulated using a solvent evaporation technique. To minimize denaturation of viral antigen during the emulsification process, serum albumin was used as a stabilizer. Use of NaHCO(3) and sucrose during the primary e...

    journal_title:Journal of microencapsulation

    pub_type: 杂志文章

    doi:10.1080/02652040802211709

    authors: Nayak B,Panda AK,Ray P,Ray AR

    更新日期:2009-03-01 00:00:00

  • Preparation of microcapsules and control of their morphology.

    abstract::For the preparation of microcapsules using the W/O/W (water in oil in water) emulsion system, it is essential to control various factors such as the dispersed state of the organic phase in the W/O/W emulsion, the difference in the solute concentration between the inner and outer aqueous phases and the volume fraction ...

    journal_title:Journal of microencapsulation

    pub_type: 杂志文章

    doi:10.1080/0265204031000093096

    authors: Kiyoyama S,Shiomori K,Kawano Y,Hatate Y

    更新日期:2003-07-01 00:00:00

  • Catechin-loaded Eudragit microparticles for the management of diabetes: formulation, characterization and in vivo evaluation of antidiabetic efficacy.

    abstract::Catechin (CT) is natural molecule proved for antidiabetic activity. Clinical application of CT is highly restricted because of its low bioavailability and ineffectiveness in in vivo conditions. Therefore, the main objective of the present investigation was to formulate CT-loaded Eudragit RS 100 microparticles and eval...

    journal_title:Journal of microencapsulation

    pub_type: 杂志文章

    doi:10.1080/02652048.2017.1337248

    authors: Meena KP,Vijayakumar MR,Dwibedy PS

    更新日期:2017-06-01 00:00:00

  • Preparation of sub-100-nm beta-lactoglobulin (BLG) nanoparticles.

    abstract::Sub-100-nm nanoparticles were prepared from beta-lactoglobulin (BLG) with a narrow size distribution by a desolvation method using glutaraldehyde for cross-linking. With pre-heating of the BLG solution to 60 degrees C and subsequent pH readjustment to 9.0, nanoparticles of 59 +/- 5 nm were obtained with improved unifo...

    journal_title:Journal of microencapsulation

    pub_type: 杂志文章

    doi:10.1080/02652040601035143

    authors: Ko S,Gunasekaran S

    更新日期:2006-12-01 00:00:00

  • Preparation and evaluation of abietic acid microcapsules by a solvent evaporation technique.

    abstract::Abietic acid was isolated from rosin N Grade (ISI) by a simple process and the product was further standardized. Sulphadiazine microcapsules were prepared by the solvent evaporation technique, using abietic acid as a wall-forming material. Discrete, spherical and free-flowing microcapsules were obtained by phase separ...

    journal_title:Journal of microencapsulation

    pub_type: 杂志文章

    doi:10.3109/02652049209040481

    authors: Puranik PK,Manekar NC,Dorle AK

    更新日期:1992-10-01 00:00:00

  • Synthesis and characterisation of chitosan-encapsulated genistein: its anti-proliferative and anti-angiogenic activities.

    abstract::Aims: The study was carried out to synthesise and characterise the chitosan-encapsulated genistein (CHI-En/Gen) and determine its anti-cancer and anti-angiogenic properties.Methods: The cytotoxic and anti-angiogenic activity of CHI-En/Gen was performed using MTT and chorioallantoic membrane assay. The molecular action...

    journal_title:Journal of microencapsulation

    pub_type: 杂志文章

    doi:10.1080/02652048.2020.1740804

    authors: Rahmani F,Karimi E,Oskoueian E

    更新日期:2020-06-01 00:00:00

  • Mixed-wall microcapsules made of cross-linked proteins and polysaccharides: preparation and properties.

    abstract::Microcapsules were prepared through an interfacial cross-linking process using terephthaloylchloride and applied to mixtures of a protein (human serum albumin or gelatin) and a polysaccharide. Their properties were compared with those of microcapsules prepared from the protein alone. Morphological characteristics of m...

    journal_title:Journal of microencapsulation

    pub_type: 杂志文章

    doi:10.3109/02652049109069560

    authors: Levy MC,Andry MC

    更新日期:1991-07-01 00:00:00

  • Mechanical characterization of microspheres - capsules, cells and beads: a review.

    abstract::Microspheres, including microcapsules and cells or beads, are widely used to produce many functional products. Information about their mechanical properties is essential to understanding their performance during manufacturing, processing and end-use applications. The mechanical characterization of microspheres require...

    journal_title:Journal of microencapsulation

    pub_type: 杂志文章,评审

    doi:10.3109/02652048.2011.646331

    authors: Mercadé-Prieto R,Zhang Z

    更新日期:2012-01-01 00:00:00

  • Development, optimization and in vitro evaluation of alginate mucoadhesive microspheres of carvedilol for nasal delivery.

    abstract::The present research work was aimed at development and optimization of alginate mucoadhesive microspheres of carvedilol for nasal delivery to avoid first pass metabolism and to improve the therapeutic efficacy in the treatment of hypertension and angina pectoris. The microspheres were prepared by a water-in-oil (w/o) ...

    journal_title:Journal of microencapsulation

    pub_type: 杂志文章

    doi:10.1080/02652040802456726

    authors: Patil SB,Sawant KK

    更新日期:2009-08-01 00:00:00

  • Anticancer potential of docetaxel-loaded cobalt ferrite nanocarrier: an in vitro study on MCF-7 and MDA-MB-231 cell lines.

    abstract:AIM:To develop a biocompatible cobalt ferrite (CF-NP) nanodrug formulation using oleic acid and poly (d,l-lactide-co-glycolic) acid (PLGA) for the delivery of docetaxel (DTX) specifically to breast cancer cells. METHODS:The CF-NP were synthesised by hydrothermal method and conjugated with DTX in a PLGA matrix and were...

    journal_title:Journal of microencapsulation

    pub_type: 杂志文章

    doi:10.1080/02652048.2020.1842529

    authors: Panda J,Satapathy BS,Mandal B,Sen R,Mukherjee B,Sarkar R,Tudu B

    更新日期:2021-01-01 00:00:00

  • Phase separation modulation and aggregation prevention: mechanism of the non-solvent addition method in the presence and absence of polyisobutylene as an additive.

    abstract::The mechanism by which microcapsule aggregation is diminished in the presence of low concentrations of adjunct non-walling polymers such as polyisobutylene (PIB) in organic solvents is uncertain. It is here investigated by phase separation studies employing the non-solvent addition method (cyclohexane) in parallel wit...

    journal_title:Journal of microencapsulation

    pub_type: 杂志文章

    doi:10.3109/02652049009028419

    authors: Donbrow M,Hoffman A,Benita S

    更新日期:1990-01-01 00:00:00

  • Protein-loaded poly(epsilon-caprolactone) microparticles. II. Muramyl dipeptide for oral controlled release of adjuvant.

    abstract::This work investigated the means for the efficient encapsulation of muramyl dipeptide (MDP) in poly(epsilon-caprolactone) (PCL) microparticles (MP) by a solvent evaporation method in order to optimize the effect of the adjuvant for oral immunization. Therefore, the influence of MDP concentration in the inner aqueous p...

    journal_title:Journal of microencapsulation

    pub_type: 杂志文章

    doi:10.1080/026520499288799

    authors: Youan BB,Benoit MA,Rollmann B,Riveau G,Gillard J

    更新日期:1999-09-01 00:00:00

  • Preparation of regular sized Ca-alginate microspheres using membrane emulsification method.

    abstract::Monodisperse Ca-alginate microspheres were prepared using the membrane emulsification method. Three ionic types of drugs (anionic, cationic and non-ionic) were incorporated into the microspheres, and the effects of sodium alginate concentration and the pressure applied during the dispersing process on the properties o...

    journal_title:Journal of microencapsulation

    pub_type: 杂志文章

    doi:10.1080/02652040010018128

    authors: You JO,Park SB,Park HY,Haam S,Chung CH,Kim WS

    更新日期:2001-07-01 00:00:00

  • Sustained-release dosage form of nitrofurantoin. Part 2. In vivo urinary excretion in man.

    abstract::The in vivo absorption of crystalline nitrofurantoin and the dosage forms of nitrofurantoin prepared with microcapsules were carried out in man by determination of urinary excretion of unchanged nitrofurantoin. The cumulative amount of drug excreted and the duration of the therapeutic urine levels were compared. The m...

    journal_title:Journal of microencapsulation

    pub_type: 杂志文章

    doi:10.3109/02652049409040444

    authors: Ertan G,Karasulu E,Abou-Nada M,Tosun M,Ozer A

    更新日期:1994-03-01 00:00:00

  • Optimisation of the microencapsulation of lavender oil by spray drying.

    abstract::Background: Lavender oil consists of around 100 components and is susceptible to volatilisation and degradation reactions. Aim: Microencapsulate lavender oil by spray drying using a biocompatible polymeric blend of gum acacia and maltodextrin to protect the oil components. Effect of total polymer content, oil loading,...

    journal_title:Journal of microencapsulation

    pub_type: 杂志文章

    doi:10.1080/02652048.2019.1620355

    authors: Burhan AM,Abdel-Hamid SM,Soliman ME,Sammour OA

    更新日期:2019-05-01 00:00:00

  • Effect of encapsulation of mefenamic acid with cationic Eudragit E on its bioavailability and gastric ulcerogenic activity in rabbits.

    abstract::Encapsulation of mefenamic acid (MFA), a potent non-steroidal anti-inflammatory drug with cationic acrylic resin, Eudragit E, was carried out using a fluidized-bed granulator (Glatt AG). Three drug:polymer ratios were prepared using 50 ml of 1, 2.5 and 5 per cent w/v aqueous suspension of Eudragit to coat 100 mg powde...

    journal_title:Journal of microencapsulation

    pub_type: 杂志文章

    doi:10.3109/02652048709021807

    authors: Ramadan EM,el-Helw A,el-Said Y

    更新日期:1987-04-01 00:00:00

  • Preparation and characterization of textile-based carrier systems for anal fissure treatment.

    abstract::Anal fissure is common and painful disease of anorectum. In this study, microparticles containing nifedipine and lidocaine HCl were prepared by spray drying and applied to bio-degradable and bio-stable tampons. Characterization of microparticles was determined by visual analyses, mass yield, particle size measurement,...

    journal_title:Journal of microencapsulation

    pub_type: 杂志文章

    doi:10.1080/02652048.2017.1393113

    authors: Sarıışık AM,Karavana SY,Türkoğlu GC,Rençber S,Önder T

    更新日期:2017-12-01 00:00:00

  • Preparation and in vitro evaluation of thiolated chitosan microparticles.

    abstract::The objective of this study was to prepare a microparticulate drug delivery system being based on a new thiomer, namely a chitosan 2-iminothiolane conjugate (chitosan-TBA conjugate). Due to thiol groups being immobilized on chitosan, chitosan-TBA conjugate exhibits improved mucoadhesive and permeation enhancing proper...

    journal_title:Journal of microencapsulation

    pub_type: 杂志文章

    doi:10.1080/02652040500162220

    authors: Maculotti K,Genta I,Perugini P,Imam M,Bernkop-Schnürch A,Pavanetto F

    更新日期:2005-08-01 00:00:00