Abstract:
:The action of two detergents, Triton X-100 and sodium dodecyl sulphate (SDS), on large, unilamellar liposomes was determined as liposome size variation, polydispersity and ability to release a soluble marker from liposomes. Triton X-100 produced stronger effects than SDS. Nevertheless, these differences in behaviour of such detergents could not be deduced from the interaction of the detergents with monolayers of the same composition as liposomes.
journal_name
J Microencapsuljournal_title
Journal of microencapsulationauthors
Hernández-Borrell J,Pons M,Juarez JC,Estelrich Jdoi
10.3109/02652049009021838subject
Has Abstractpub_date
1990-04-01 00:00:00pages
255-9issue
2eissn
0265-2048issn
1464-5246journal_volume
7pub_type
杂志文章abstract::Microcapsules were prepared through an interfacial cross-linking process using terephthaloylchloride and applied to mixtures of a protein (human serum albumin or gelatin) and a polysaccharide. Their properties were compared with those of microcapsules prepared from the protein alone. Morphological characteristics of m...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.3109/02652049109069560
更新日期:1991-07-01 00:00:00
abstract::Captopril microcapsules were prepared using four different viscosity grades of ethyl cellulose (core: wall ratios 1:1, 1:2 and 1:3) by temperature induced coacervation from cyclohexane. In vitro dissolution studies in 0.1 M hydrochloric acid showed that the drug release was dependent on the core to wall ratio, the vis...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.3109/02652049009028424
更新日期:1990-01-01 00:00:00
abstract::Polyurethane modified with polylactic acid microcapsules were fabricated for controlled release of chlorpyrifos (one of the high usage solid phosphorous insecticides) via interfacial polymerisation with diphenylmethane diisocyanate, polyether triol, 1,4-butanediol and polylactic acid as modifier. The structure, morpho...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.1080/02652048.2019.1599075
更新日期:2019-01-01 00:00:00
abstract::Poly(lactic acid) microcapsules of pilocarpine hydrochloride were prepared and evaluated by measuring a miotic effect in rabbits. The microcapsule suspension showed prolongation of miosis and an improved bioavailability when compared with a standard eye dosage form. ...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.3109/02652048509033840
更新日期:1985-10-01 00:00:00
abstract::Bacampicillin hydrochloride has been microencapsulated to mask its very bitter taste. The objective of the study was to compare the in vitro release and bioavailability of bacampicillin hydrochloride from microcapsules coated with two principally different polymers: a water-insoluble polymer, ethylcellulose, and an ac...
journal_title:Journal of microencapsulation
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.3109/02652048509031556
更新日期:1985-04-01 00:00:00
abstract::Catechin (CT) is natural molecule proved for antidiabetic activity. Clinical application of CT is highly restricted because of its low bioavailability and ineffectiveness in in vivo conditions. Therefore, the main objective of the present investigation was to formulate CT-loaded Eudragit RS 100 microparticles and eval...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.1080/02652048.2017.1337248
更新日期:2017-06-01 00:00:00
abstract::An extrusion-based encapsulation process has been developed for making salt grain-sized iron premix for salt fortification. The first step of extrusion agglomeration process has been studied and reported previously. The focus of this study is on the optimisation of the colour-masking and polymer coating steps. Several...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.3109/02652048.2011.651493
更新日期:2012-01-01 00:00:00
abstract::Nanoparticles prepared of human serum albumin (HSA) represent promising carriers for drug delivery. Desolvating procedure is a common method to obtain protein-based particles. However process parameters have a great influence on size, size distribution and particle yield of the resulting formulation. Therefore, it is ...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.3109/02652048.2011.635218
更新日期:2012-01-01 00:00:00
abstract::Indomethacin-loaded dietheylaminoethyl trisacryl microspheres (DEAE-MS), originally designed for therapeutic embolization, were encapsulated using two methods: coacervation and solvent evaporation/extraction. This encapsulation was achieved using a biocompatible polymer, the PLGA 50 : 50, and aimed to control the rele...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.1080/02652040701843388
更新日期:2008-03-01 00:00:00
abstract::The mechanism by which microcapsule aggregation is diminished in the presence of low concentrations of adjunct non-walling polymers such as polyisobutylene (PIB) in organic solvents is uncertain. It is here investigated by phase separation studies employing the non-solvent addition method (cyclohexane) in parallel wit...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.3109/02652049009028419
更新日期:1990-01-01 00:00:00
abstract::Cis-parinaric acid is fluorescent when partioned into a lipid environment and its fluorescence is destroyed upon reaction with free radicals. In our study 1-palmitoyl-2-parinoyl-phosphatidylcholine (cis-PnA) has been used to monitor the time-course of liposomal lipid peroxidation, using reverse-phase evaporation vesic...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.3109/02652049609026029
更新日期:1996-07-01 00:00:00
abstract:PURPOSE:This investigation was undertaken to develop glyceryl monostearate (Geleol)-based solid lipid nanoparticles (SLNs) of a hydrophilic drug ciprofloxacin HCl. METHODS:Hansen's solubility parameter study was carried out in screening of a suitable carrier and solvent system. Subsequently, SLNs were prepared by solv...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.3109/02652048.2011.651498
更新日期:2012-01-01 00:00:00
abstract::Redox-responsive magnetic protein microcapsules with Fe3O4 magnetic nanoparticles (MNPs) encapsulated inside have been obtained using a facile, cost-effective and fast sonochemical method from hen egg white proteins. Such prepared redox-responsive magnetic hen egg white protein microcapsules (MHEWPMCs) could be easily...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.3109/02652048.2015.1073389
更新日期:2015-01-01 00:00:00
abstract::Encapsulation of mefenamic acid (MFA), a potent non-steroidal anti-inflammatory drug with cationic acrylic resin, Eudragit E, was carried out using a fluidized-bed granulator (Glatt AG). Three drug:polymer ratios were prepared using 50 ml of 1, 2.5 and 5 per cent w/v aqueous suspension of Eudragit to coat 100 mg powde...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.3109/02652048709021807
更新日期:1987-04-01 00:00:00
abstract::The sustained delivery of multiple agents to the lung offers potential benefits to patients. This study explores the preparation of highly respirable dual-loaded spray-dried double emulsions. Spray-dried powders were produced from water-in-oil-in-water (w/o/w) double emulsions, containing salbutamol sulphate and/or be...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.1080/02652040903052044
更新日期:2010-01-01 00:00:00
abstract::Atomic force microscopy (AFM) is recognized a suitable and powerful technique for surface and morphological analysis. Even if until now this technique has not been frequently used in the pharmaceutical field, it can contribute to an accurate morphologic characterization of microspheres and nanospheres. In this work, a...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.1080/02652040500435220
更新日期:2006-03-01 00:00:00
abstract::The aim of this study was to develop and characterize diclofenac sodium loaded-cellulose acetate butyrate microparticles in order to obtain a controlled-release system. The influence of the type of polymer, the volume and composition of the internal phase, drug loading, surfactant concentration and additive added on m...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.1080/02652040701747928
更新日期:2008-02-01 00:00:00
abstract::Chronic osteomyelitis is still the cause of many problems in orthopaedics in terms of therapy and infection persistence. Four-to-six week systemic antibiotic therapy is required along with bone and soft tissue debridement in the therapy of chronic osteomyelitis. Prolonged-release local antibiotic therapy has been take...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.1080/0265204031000154179
更新日期:2003-11-01 00:00:00
abstract::The in vivo absorption of crystalline nitrofurantoin and the dosage forms of nitrofurantoin prepared with microcapsules were carried out in man by determination of urinary excretion of unchanged nitrofurantoin. The cumulative amount of drug excreted and the duration of the therapeutic urine levels were compared. The m...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.3109/02652049409040444
更新日期:1994-03-01 00:00:00
abstract::Ibuprofen-loaded polystyrene microparticles were prepared by the emulsion-solvent evaporation process from an aqueous system. The effects of different parameters on the drug content and on the release of the drug from the microparticles were investigated. The drug content, in all the formulations, was less than the th...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.1080/026520400288553
更新日期:2000-01-01 00:00:00
abstract::To prepare the sustained release vitamin C carriers, vitamin C was successfully encapsulated in tripolyphosphate (TPP) cross-linked chitosan (TPP-chitosan) microspheres by the spray-drying method at different manufacturing conditions. Manufacturing parameters (inlet temperature, liquid flow rate, chitosan concentratio...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.1080/02652040500435436
更新日期:2006-02-01 00:00:00
abstract::PLGA microspheres with high drug loading and high encapsulation efficiency were fabricated by a novel solvent evaporation process-in-situ S/O/W process. Insulin was dissolved in DMSO and dispersed into DCM to form fine particles due to an anti-solvent effect. The in-situ formed suspension was then added into an aqueou...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.1080/02652040600687613
更新日期:2006-08-01 00:00:00
abstract::Polyisohexylcyanoacrylate nanocapsules containing cyclosporin were prepared by mixing in a 1:2 ratio an oil/ethanol solution of monomer and drug with an aqueous phase. Drug nanoencapsulation rate was controlled by its partition coefficient between the inner (organic) and outer (aqueous) phases. Thus highest encapsulat...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.3109/02652049109021233
更新日期:1992-04-01 00:00:00
abstract::To overcome the recurrence problem in bladder tumours; nanoparticles with positive surface charge may improve interaction with biological membranes for intravesical administration. The aim of this study was to design, develop and evaluate (in vitro-in vivo) cationic nanoparticles based on chitosan, poly-L-lysine or po...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.3109/02652048.2012.668957
更新日期:2012-01-01 00:00:00
abstract::Enteric diastase spherules were prepared using cellulose acetate phthalate and eudragit RS-100 by emulsion solvent removal method. Factors that could affect the size shape and diastatic activity were studied. The studied factors include pH of aqueous media, temperature of dispersion media and concentration of surface ...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.3109/02652049109021868
更新日期:1991-10-01 00:00:00
abstract::The transport pathway of PBCA nanoparticles through the rabbit cornea and conjunctiva was studied using fluorescence microscopy. Nanoparticles were produced by an emulsion-polymerization process, purified by a GPC procedure, and labelled with rhodamine 6G or propidium iodide as fluorescent laser dyes. The stability of...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.3109/02652049109021873
更新日期:1991-10-01 00:00:00
abstract::The objective of this study was to prepare floating theophylline microspheres with zero order release profiles for use as buoyant reservoirs with increased retention time in the stomach. The microspheres were prepared by a modified emulsion-solvent evaporation method using a polymer mixture of cellulose acetate butyra...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.3109/02652049809008255
更新日期:1998-11-01 00:00:00
abstract::Polylactide (PLA) and polylactide-co-glycolide (PLGA) particles entrapping rotavirus (strain SA11) were formulated using a solvent evaporation technique. To minimize denaturation of viral antigen during the emulsification process, serum albumin was used as a stabilizer. Use of NaHCO(3) and sucrose during the primary e...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.1080/02652040802211709
更新日期:2009-03-01 00:00:00
abstract::Capsules have been prepared based on a polyanion blend of sodium alginate and sodium cellulose sulphate, gelled in the presence of calcium chloride and sodium chloride. In a second step a membrane was formed via the addition of polymethylene-co-guanidine (PMCG), an oligocation. A mechanistic study examined the influen...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.1080/02652040601058418
更新日期:2007-02-01 00:00:00
abstract::This study demonstrates the feasibility of using a single-capillary electrospray (ES) system to generate novel alpha-lipoic acid encapsulated poly(ethylene oxide)-chitosan (ALA/PEO/CS) particles with a monodispersed diameter. Scanning electron microscopic images (SEM) and dynamic light scattering (DLS) results indicat...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.3109/02652048.2013.863395
更新日期:2014-01-01 00:00:00