Preparation and in vitro evaluation of thiolated chitosan microparticles.

abstract：:In this study, ethylcellulose and acrylate-methacrylate copolymer (Eudragit RL 100, Eudragit RS 100) membranes were prepared by using appropriate types and amounts of plasticizers. Thirty percent and 20% of triacetin based on polymer weight were found to be appropriate plasticizers for ethylcellulose membranes and acr...

journal_title：Journal of microencapsulation

authors： Nimmannit U,Suwanpatra N

更新日期：1996-11-01 00:00:00

abstract：CONTEXT:Solid lipid nanoparticles (SLNs) can efficiently and efficaciously incorporate anti-cancer agents. OBJECTIVE:To prepare and characterise tamoxifen (TAM)-loaded SLNs. MATERIALS AND METHODS:Glyceryl monostearate, Tween-80, and trehalose were used in SLNs. SLNs were tested via dynamic light scattering (DLS), tra...

journal_title：Journal of microencapsulation

authors： Lakkadwala S,Nguyen S,Lawrence J,Nauli SM,Nesamony J

更新日期：2014-01-01 00:00:00

abstract：:The preparation of dipyridamole (DIP) alginate (alg) microspheres by different methods or the incorporation of tragacanth (trgh), pectin or Eudragit L-100 55 (Eud) in alg microsphere formulations did not provide a prolonged release of DIP at pH 1.2. Tabletted microsphere formulations containing alg, trgh, pectin, sodi...

journal_title：Journal of microencapsulation

authors： Gürsoy A,Karakuş D,Okar I

更新日期：1999-07-01 00:00:00

abstract：:Redox-responsive magnetic protein microcapsules with Fe3O4 magnetic nanoparticles (MNPs) encapsulated inside have been obtained using a facile, cost-effective and fast sonochemical method from hen egg white proteins. Such prepared redox-responsive magnetic hen egg white protein microcapsules (MHEWPMCs) could be easily...

journal_title：Journal of microencapsulation

authors： Zhong S,Cui X,Tian F

更新日期：2015-01-01 00:00:00

abstract：:An overview of biodegradable and biocompatible microcapsules and microspheres loaded with neuroactive substances, or cells producing neuroactive substances, and their role as drug delivery systems (DDS) for drug administration to the central nervous system (CNS) is given. In addition, closely related systems are also ...

journal_title：Journal of microencapsulation

authors： Filipović-Grcić J,Maysinger D,Jalsenjak I

更新日期：1995-07-01 00:00:00

abstract：:D,L-polylactic acid (PLA) microspheres containing quinidine base and quinidine sulphate were prepared by the solvent evaporation method. The present study was carried out to examine how various process parameters in the aqueous phase influenced the preparation and properties of PLA-microspheres. The amount of drug tha...

journal_title：Journal of microencapsulation

authors： Bodmeier R,McGinity JW

更新日期：1987-10-01 00:00:00

abstract：:Liposomes containing Isovist were prepared by controlled detergent dialysis as well as by reverse phase evaporation. After preparation these liposomes were lyophilized and then submitted to sterilization by ethylene oxide. Prior to lyophilization, trehalose was added as a protective agent to preserve the size of the l...

journal_title：Journal of microencapsulation

authors： Ratz H,Freise J,Magerstedt P,Schaper A,Preugschat W,Keyser D

更新日期：1989-10-01 00:00:00

abstract：:Graft copolymer polyethylenimine-graft-poly(N-vinylpyrrolidone) (PEI-g-PVP) was prepared by coupling mono carboxyl-terminated PVP (PVP-COOH) with PEI using N,N'-dicyclohexylcarbodiimide (DCC) and N-hydroxysuccinimide (NHS) as coupling agents. In aqueous medium, PVP-g-PEI can self-assemble into stable polyion complex m...

journal_title：Journal of microencapsulation

authors： Yuan J,Luo Y,Gao Q

更新日期：2011-01-01 00:00:00

abstract：:Solid lipid nanoparticles (SLNs) and nanosuspensions (NSs) have shown great promise for improving bioavailability of poorly water-soluble drugs. This study was aimed to develop SLNs and NS of Saquinavir (SQ) for improvement in bioavailability. These formulations were characterized and their pharmacokinetics and biodis...

journal_title：Journal of microencapsulation

authors： Dodiya SS,Chavhan SS,Sawant KK,Korde AG

更新日期：2011-01-01 00:00:00

abstract：:Enteric diastase spherules were prepared using cellulose acetate phthalate and eudragit RS-100 by emulsion solvent removal method. Factors that could affect the size shape and diastatic activity were studied. The studied factors include pH of aqueous media, temperature of dispersion media and concentration of surface ...

journal_title：Journal of microencapsulation

authors： Vyas SP,Gogoi PJ,Pande S,Dixit VK

更新日期：1991-10-01 00:00:00

abstract：:H-n.m.r. spectroscopy of small unilamellar phospholipid vesicles in the presence of the lanthanide probe ion Dy3+ has been used to study the permeability of these liposomes induced by the bile salts (glycocholate and glycodeoxycholate) and pancreatic phospholipase A2. A marked synergism is demonstrated in the combined...

journal_title：Journal of microencapsulation

authors： Hunt GR,Jones IC

更新日期：1984-04-01 00:00:00

abstract：:The entrapment of clofazimine (CLO) in a liposomal delivery system for topical application can protect it from absorption into the blood circulation and increase its residence time within the skin. This may reduce the very long mean period of leprosy treatment, as well as the side effects due to the long term administ...

journal_title：Journal of microencapsulation

authors： Patel VB,Misra AN

更新日期：1999-05-01 00:00:00

abstract：:We demonstrate the microencapsulation of a double-base (DB) rocket propellant stabiliser, 2-nitrodiphenylamine (2-NDPA), that can potentially increase the shelf life of DB rocket propellants. Poly(lactide-co-glycolide) (PLG) microspheres loaded with 2-NDPA were prepared using the oil-in-water emulsion technique. The m...

journal_title：Journal of microencapsulation

authors： Shorty M,Singh S,Jebrail FF,Andrews MJ

更新日期：2012-01-01 00:00:00

abstract：:The diblock copolymers based on PBLG and PEO (GE) were synthesized and characterized. Nanoparticles showed spherical shape from the observations of TEM and approved core-shell structure. Drug contents were increased with use of higher initial drug concentration and higher Mw of GE. Nifedipine (NFD) release rate was sl...

journal_title：Journal of microencapsulation

authors： Jeong YI,Sun HS,Shim YH,Kim C,Park SH,Choi KC,Cho CS

更新日期：2004-06-01 00:00:00

abstract：:This paper describes a novel approach to prepare and characterize calcium-shellac spheres as a carrier of a tooth whitening agent carbamide peroxide. Calcium-shellac spheres were prepared using an extrusion technique based on dropping aqueous ammonium shellac solution into calcium chloride solution. The effects of for...

journal_title：Journal of microencapsulation

authors： Xue J,Zhang Z

更新日期：2008-12-01 00:00:00

abstract：:Monodisperse Ca-alginate microspheres were prepared using the membrane emulsification method. Three ionic types of drugs (anionic, cationic and non-ionic) were incorporated into the microspheres, and the effects of sodium alginate concentration and the pressure applied during the dispersing process on the properties o...

journal_title：Journal of microencapsulation

authors： You JO,Park SB,Park HY,Haam S,Chung CH,Kim WS

更新日期：2001-07-01 00:00:00

abstract：:The objective of this study was to prepare floating theophylline microspheres with zero order release profiles for use as buoyant reservoirs with increased retention time in the stomach. The microspheres were prepared by a modified emulsion-solvent evaporation method using a polymer mixture of cellulose acetate butyra...

journal_title：Journal of microencapsulation

authors： Stithit S,Chen W,Price JC

更新日期：1998-11-01 00:00:00

abstract：:The action of two detergents, Triton X-100 and sodium dodecyl sulphate (SDS), on large, unilamellar liposomes was determined as liposome size variation, polydispersity and ability to release a soluble marker from liposomes. Triton X-100 produced stronger effects than SDS. Nevertheless, these differences in behaviour o...

journal_title：Journal of microencapsulation

authors： Hernández-Borrell J,Pons M,Juarez JC,Estelrich J

更新日期：1990-04-01 00:00:00

abstract：:The present research work was aimed at development and optimization of alginate mucoadhesive microspheres of carvedilol for nasal delivery to avoid first pass metabolism and to improve the therapeutic efficacy in the treatment of hypertension and angina pectoris. The microspheres were prepared by a water-in-oil (w/o) ...

journal_title：Journal of microencapsulation

authors： Patil SB,Sawant KK

更新日期：2009-08-01 00:00:00

abstract：:Chitosan microspheres were prepared by an emulsion-phase separation technique without the use of chemical cross-linking agents; alternatively, ionotropic gelation was employed in a w/o emulsion. The possibility of three kinds of anions (tripolyphosphate, citrate and sulphate) to interact with chitosan was investigated...

journal_title：Journal of microencapsulation

authors： Shu XZ,Zhu KJ

更新日期：2001-03-01 00:00:00

abstract：:Sub-100-nm nanoparticles were prepared from beta-lactoglobulin (BLG) with a narrow size distribution by a desolvation method using glutaraldehyde for cross-linking. With pre-heating of the BLG solution to 60 degrees C and subsequent pH readjustment to 9.0, nanoparticles of 59 +/- 5 nm were obtained with improved unifo...

journal_title：Journal of microencapsulation

authors： Ko S,Gunasekaran S

更新日期：2006-12-01 00:00:00

abstract：:Using liposomes radiolabelled by the 99mTechnetium-stannous chloride technique we have investigated the effect of surface charge on the stability of the isotope in vitro and in vivo. Dialysis of 99mTc-labelled positive, negative and neutral liposomes, which had been incubated in either saline or normal rat serum showe...

journal_title：Journal of microencapsulation

authors： Love WG,Amos N,Williams BD,Kellaway IW

更新日期：1989-01-01 00:00:00

abstract：:The factors influencing the encapsulation of azathioprine (AZA) into liposomes were investigated to find out the conditions for its optimal entrapment. Similar studies for comparison were also carried out on 6-mercaptopurine (6-MP), of which AZA is a prodrug. AZA and also 6-MP show higher encapsulation efficiencies in...

journal_title：Journal of microencapsulation

authors： Gulati M,Grover M,Singh M,Singh S

更新日期：1998-07-01 00:00:00

abstract：:This paper prepared novel biodegradable and pH-sensitive microgels based on Poly(epsilon-caprolactone)-Pluronic-Poly(epsilon-caprolactone)-dimethacrylate (PCFC-DMA), Poly(ethylene glycol) dimethacrylate (PEG-DMA) and methylacrylic acid (MAA) cross-linked with N,N'-methylenebisacrylamide (BIS), initiated by NaHSO(3), K...

journal_title：Journal of microencapsulation

authors： Xu X,Fu S,Wang K,Jia W,Guo G,Zheng X,Dong P,Guo Q,Qian Z

更新日期：2009-11-01 00:00:00

abstract：:Conditions of microencapsulation by in situ polycondensation, using melamine-formaldehyde as wall material, are influenced by the chemical nature of the core to encapsulate. In our study concerning the encapsulation of a photopolymerizable phase containing an electrically charged compound, it was necessary to modify t...

journal_title：Journal of microencapsulation

authors： Pernot JM,Brun H,Pouyet B,Sergent M,Phan-Tan-Luu R

更新日期：1993-07-01 00:00:00

abstract：:Monodisperse albumin microspheres were successfully prepared by both chemical or thermal hardening methods via membrane emulsification using microporous glass membranes with uniform pore sizes. The monodispersity of the microspheres was found to depend strongly on parameters such as albumin concentration, emulsifier c...

journal_title：Journal of microencapsulation

authors： el-Mahdy M,Ibrahim ES,Safwat S,el-Sayed A,Ohshima H,Makino K,Muramatsu N,Kondo T

更新日期：1998-09-01 00:00:00

abstract：:The microencapsulation of drugs is gaining importance in many research activities. A common technique for preparing microcapsules is the solvent evaporation method which is simple but has a large number of reaction control parameters. This study reports the microcapsulation of allopurinol by the solvent evaporation me...

journal_title：Journal of microencapsulation

authors： Arabi H,Hashemi SA,Fooladi M

更新日期：1996-09-01 00:00:00

abstract：:PLA microparticles containing 17-β-estradiol valerate were prepared by an emulsion/evaporation method in order to sustain drug release. This system was characterized concerning particle size, particle morphology and the influence of formulation and processing parameters on drug encapsulation and in vitro drug release....

journal_title：Journal of microencapsulation

authors： Machado SR,Lunardi LO,Tristão AP,Marchetti JM

更新日期：2009-05-01 00:00:00

abstract：:The size dependent and size independent contributions to the mechanical properties of poly(ethyleneglycol) microspheres with encapsulated air, made for medical ultrasound imaging, have been studied. A relation between the size of microspheres in a reference group and their acoustic attenuation efficacy was derived by ...

journal_title：Journal of microencapsulation

authors： Dyrstad K,Sontum PC,Hoff L

更新日期：2000-05-01 00:00:00

abstract：:This work demonstrates Box-Behnken design (BBD)'s capability in exploring scientific principles governing a process, different from its use in process optimisation. We have investigated nanoprecipitation (NP) of temozolomide with polycaprolactone. Five factors, surfactant, stirring speed (SS), dropping rate (DR), phas...

journal_title：Journal of microencapsulation

authors： Singh Y,Ojha P,Srivastava M,Chourasia MK

更新日期：2015-01-01 00:00:00