Study of azathioprine encapsulation into liposomes.

abstract：:We demonstrate the microencapsulation of a double-base (DB) rocket propellant stabiliser, 2-nitrodiphenylamine (2-NDPA), that can potentially increase the shelf life of DB rocket propellants. Poly(lactide-co-glycolide) (PLG) microspheres loaded with 2-NDPA were prepared using the oil-in-water emulsion technique. The m...

journal_title：Journal of microencapsulation

authors： Shorty M,Singh S,Jebrail FF,Andrews MJ

更新日期：2012-01-01 00:00:00

abstract：:This study demonstrates the feasibility of using a single-capillary electrospray (ES) system to generate novel alpha-lipoic acid encapsulated poly(ethylene oxide)-chitosan (ALA/PEO/CS) particles with a monodispersed diameter. Scanning electron microscopic images (SEM) and dynamic light scattering (DLS) results indicat...

journal_title：Journal of microencapsulation

authors： Bai MY,Hu YM

更新日期：2014-01-01 00:00:00

abstract：:Microspheres, including microcapsules and cells or beads, are widely used to produce many functional products. Information about their mechanical properties is essential to understanding their performance during manufacturing, processing and end-use applications. The mechanical characterization of microspheres require...

journal_title：Journal of microencapsulation

authors： Mercadé-Prieto R,Zhang Z

更新日期：2012-01-01 00:00:00

abstract：:Prototype fragrances, prepared from common fragrance components, were extracted with water, recovered, and characterized by gas chromatography before and after the water treatment, revealing a significant loss of the more water-soluble components. Unextracted prototype fragrances were also microencapsulated by a gelat...

journal_title：Journal of microencapsulation

authors： Flores RJ,Wall MD,Carnahan DW,Orofino TA

更新日期：1992-07-01 00:00:00

abstract：:Oil-containing polyterephthalamide microcapsules were synthesized by the interfacial polymerization of an oil-soluble monomer (terephthaloyl dichloride, TDC) and a mixture of two water-soluble monomers (diethylenetriamine, DETA, and 1, 6-hexamethylenediamine, HMDA). The influence of several synthesis parameters (e.g. ...

journal_title：Journal of microencapsulation

authors： Alexandridou S,Kiparissides C,Mange F,Foissy A

更新日期：2001-11-01 00:00:00

abstract：:A considerable effort has been spent in the past three decades to investigate various aspects of liposomes as novel drug delivery systems. In 1990, the first amphotericin B (AmB) liposomal preparation (L-AmB) under the brand name AmBisome was introduced into the market by Vestar. The successful marketing of the produc...

journal_title：Journal of microencapsulation

authors： Gulati M,Bajad S,Singh S,Ferdous AJ,Singh M

更新日期：1998-03-01 00:00:00

abstract：:Background: Lavender oil consists of around 100 components and is susceptible to volatilisation and degradation reactions. Aim: Microencapsulate lavender oil by spray drying using a biocompatible polymeric blend of gum acacia and maltodextrin to protect the oil components. Effect of total polymer content, oil loading,...

journal_title：Journal of microencapsulation

authors： Burhan AM,Abdel-Hamid SM,Soliman ME,Sammour OA

更新日期：2019-05-01 00:00:00

abstract：:Vascular endothelial growth factor receptor (VEGFR) is over-expressed on a variety of tumour cells and tumour neovasculature, and so becomes well-documented target for cancer treatment. This study was designed to evaluate the cellular targeting and anti-tumor potency of VEGF-conjugated nanoparticles (VEGF-NPs). The po...

journal_title：Journal of microencapsulation

authors： Shi Y,Zhou M,Zhang J,Lu W

更新日期：2015-01-01 00:00:00

abstract：:The sustained delivery of multiple agents to the lung offers potential benefits to patients. This study explores the preparation of highly respirable dual-loaded spray-dried double emulsions. Spray-dried powders were produced from water-in-oil-in-water (w/o/w) double emulsions, containing salbutamol sulphate and/or be...

journal_title：Journal of microencapsulation

authors： Learoyd TP,Burrows JL,French E,Seville PC

更新日期：2010-01-01 00:00:00

abstract：:Microcapsules containing fragrant oil (Foral oil) were synthesized via the in situ polymerization method using melamine-formaldehyde (M-F) as a wall material. The encapsulation efficiency and other physical properties were analysed with varying formaldehyde/melamine (F/M) mole ratio and pH of emulsion medium. The pH o...

journal_title：Journal of microencapsulation

authors： Lee HY,Lee SJ,Cheong IW,Kim JH

更新日期：2002-09-01 00:00:00

abstract：CONTEXT:Flavonoids show promising anticancer potential but it is limited due to poor solubility. OBJECTIVE:The present investigation was to prepare Chrysin-Phospholipid complex loaded solid lipid nanoparticles (Ch-PC-SLNs) for improving its encapsulation as compared to that of Chrysin loaded SLNs (Ch-SLNs) and evaluat...

journal_title：Journal of microencapsulation

authors： Komath S,Garg A,Wahajuddin M

更新日期：2018-09-01 00:00:00

abstract：:The effect of lecithin and starch on viability of alginate encapsulated probiotics was determined at different temperatures. Probiotic organisms (1% v/v>10Log CFU ml(-1)) were encapsulated using alginate (2% w/v), gelatinized starches (2% w/v) and lecithin (0-4% w/v) and stored in sealed containers at 4, 23 and 37 deg...

journal_title：Journal of microencapsulation

authors： Donthidi AR,Tester RF,Aidoo KE

更新日期：2010-01-01 00:00:00

abstract：:Microcapsules were prepared through an interfacial cross-linking process using terephthaloylchloride and applied to mixtures of a protein (human serum albumin or gelatin) and a polysaccharide. Their properties were compared with those of microcapsules prepared from the protein alone. Morphological characteristics of m...

journal_title：Journal of microencapsulation

authors： Levy MC,Andry MC

更新日期：1991-07-01 00:00:00

abstract：:The development of microparticulate food particles for marine suspension-feeders is discussed with respect to the difficulties of nutrient delivery in the aquatic environment and to feeding and digestion in crustacea and bivalve molluscs. Loss of nutrients from particles suspended in seawater must be minimized by eith...

journal_title：Journal of microencapsulation

authors： Langdon CJ,Levine DM,Jones DA

更新日期：1985-01-01 00:00:00

abstract：:Transplantation of cells genetically modified to produce neurotrophins is a promising spinal cord repair strategy. Previously we showed that fibroblasts engineered to produce brain-derived neurotrophic factor (Fb/BDNF) microencapsulated in alginate survive, continue to grow and express bioactive BDNF. We here compared...

journal_title：Journal of microencapsulation

authors： Francis NL,Shanbhag MS,Fischer I,Wheatley MA

更新日期：2011-01-01 00:00:00

abstract：PURPOSE:To develop a stable and reproducible modified release pellet formulation containing ibuprofen. METHODS:Using extrusion-spheronization technology to produce pellets. RESULTS:The percentage yield, size distribution and overall pellet shape within the desired size range of 1000-1400 microm was found to be depend...

journal_title：Journal of microencapsulation

authors： Lutchman D,Dangor CM,Perumal D

更新日期：2005-09-01 00:00:00

abstract：:The soft microcapsules containing eucalyptus oil, ubiquinone and the fine water droplets could be prepared with interfacial dehydration reaction between hydroxy methyl cellulose and tannic acid using the water-in-oil-in-water type multiple (W/O)/W emulsion. The diameters of the microcapsules and the content and the mi...

journal_title：Journal of microencapsulation

authors： Taguchi Y,Suzuki T,Saito N,Yokoyama H,Tanaka M

更新日期：2017-12-01 00:00:00

abstract：:Ibuprofen-loaded polystyrene microparticles were prepared by the emulsion-solvent evaporation process from an aqueous system. The effects of different parameters on the drug content and on the release of the drug from the microparticles were investigated. The drug content, in all the formulations, was less than the th...

journal_title：Journal of microencapsulation

authors： Tamilvanan S,Sa B

更新日期：2000-01-01 00:00:00

abstract：:The transport pathway of PBCA nanoparticles through the rabbit cornea and conjunctiva was studied using fluorescence microscopy. Nanoparticles were produced by an emulsion-polymerization process, purified by a GPC procedure, and labelled with rhodamine 6G or propidium iodide as fluorescent laser dyes. The stability of...

journal_title：Journal of microencapsulation

authors： Zimmer A,Kreuter J,Robinson JR

更新日期：1991-10-01 00:00:00

abstract：:Artificial chylomicron remnants were investigated as a new drug carrier system for the targeting of hepatic parenchymal cells. The emulsions presented here are similar in particle size and composition to natural lipoproteins. The preparations contained triolein, phospholipid, cholesterol and cholesteryl oleate. Egg yo...

journal_title：Journal of microencapsulation

authors： Vuaridel-Bonanomi ES,Weder HG

更新日期：1991-04-01 00:00:00

abstract：AIM:This study aimed to evaluate the protective effect of flaxseed mucilage on the co-extrusion microencapsulation of Lactobacillus rhamnosus GG. METHODS:Core flow rate, chitosan coating, and flaxseed mucilage concentration were optimised for the microencapsulation of L. rhamnosus. The microbeads were characterised an...

journal_title：Journal of microencapsulation

authors： Lai K,How Y,Pui L

更新日期：2020-12-28 00:00:00

abstract：:Cis-parinaric acid is fluorescent when partioned into a lipid environment and its fluorescence is destroyed upon reaction with free radicals. In our study 1-palmitoyl-2-parinoyl-phosphatidylcholine (cis-PnA) has been used to monitor the time-course of liposomal lipid peroxidation, using reverse-phase evaporation vesic...

journal_title：Journal of microencapsulation

authors： Di Giulio A,Saletti A,Oratore A,Bozzi A

更新日期：1996-07-01 00:00:00

abstract：:This article describes the development of a freeze-dried formulation of chitosan (CS) nanocapsules containing docetaxel (DCX) and the evaluation of its efficacy in the NCI-H460 cancer cell line. More specifically, two prototypes of nanocapsules differing in their coating, CS alone or in combination with poloxamer 188 ...

journal_title：Journal of microencapsulation

authors： Lozano MV,Esteban H,Brea J,Loza MI,Torres D,Alonso MJ

更新日期：2013-01-01 00:00:00

abstract：:This work aimed to investigate the potential effect of cyclodextrin encapsulation on intrinsic ability of daidzein (DAD) and genistein (GEN) to inhibit the glycosaminoglycan (GAG) synthesis in fibroblasts originating from patients with mucopolysaccharidosis (MPS), type II and III. DAD or GEN encapsulation with either ...

journal_title：Journal of microencapsulation

authors： Fumić B,Jablan J,Cinčić D,Zovko Končić M,Jug M

更新日期：2018-01-01 00:00:00

abstract：:Secretory leukocyte protease inhibitor (SLPI) is an endogenous serine protease inhibitor that protects the lungs from excessive tissue damage caused by leukocyte proteases released during inflammation. Recombinant SLPI (rSLPI) has shown potential as a treatment for inflammatory lung conditions. To date, its clinical a...

journal_title：Journal of microencapsulation

authors： Gibbons AM,McElvaney NG,Taggart CC,Cryan SA

更新日期：2009-09-01 00:00:00

abstract：:A biocompatible emulsification method has been developed for microencapsulation of live cells and enzymes within a calcium alginate matrix. Fabrication of alginate beads was achieved by premixing a sequestering agent (sodium polyphosphate) and the calcium source (calcium sulphate) with the hydrogel monomer prior to th...

journal_title：Journal of microencapsulation

authors： Monshipouri M,Price RR

更新日期：1995-05-01 00:00:00

abstract：:Polyelectrolyte complexes (PEC) provide new opportunities for controlled release system of drugs, and have potentials to address challenges on the way to effective oral insulin delivery. Here, an innovative pH-sensitive PEC for insulin oral administration was developed, which was formed by self-assembly of two opposit...

journal_title：Journal of microencapsulation

authors： Chen T,Li S,Zhu W,Liang Z,Zeng Q

更新日期：2019-01-01 00:00:00

abstract：:Low molecular weight heparin (LMWH)-loaded flexible liposomes (flexosomes) were formulated for transdermal delivery, and their physicochemical and pharmacokinetic parameters were compared with LMWH-loaded ethosomes. Flexosomes had similar particle size compared with ethosomes, but their deformability was higher than t...

journal_title：Journal of microencapsulation

authors： Song YK,Hyun SY,Kim HT,Kim CK,Oh JM

更新日期：2011-01-01 00:00:00

abstract：:In this study, we formulated a microparticulate melanoma cancer vaccine via the transdermal route. The vaccine was delivered using microneedle-based Dermaroller® which is available for cosmetic purposes. Unlike subcutaneous injections, administration using microneedles is painless and in general can increase the perme...

journal_title：Journal of microencapsulation

authors： Bhowmik T,D'Souza B,Shashidharamurthy R,Oettinger C,Selvaraj P,D'Souza MJ

更新日期：2011-01-01 00:00:00

abstract：:The regularities of release of therapeutic antioxidant enzyme superoxide dismutase (SOD) from various alginate-based delivery systems (DS) into simulated gastric and intestinal fluids were determined. The following systems were used: Ca-alginate granules (AG) prepared by various methods, porous carbonate cores with mu...

journal_title：Journal of microencapsulation

authors： Sudareva N,Suvorova O,Saprykina N,Vilesov A,Bel'tyukov P,Petunov S

更新日期：2016-08-01 00:00:00