An investigation of internal phase losses during the microencapsulation of fragrances.

abstract：:The present study describes the development of a new cyclosporine formulation based on polycaprolactone (PCL) microspheres (MS) prepared by the solvent evaporation method. Ternary phase diagrams were used to identify the domains where MS were formed. The application of central composite designs established the influen...

journal_title：Journal of microencapsulation

authors： Aberturas MR,Molpeceres J,Guzmán M,García F

更新日期：2002-01-01 00:00:00

abstract：:To prepare the sustained release vitamin C carriers, vitamin C was successfully encapsulated in tripolyphosphate (TPP) cross-linked chitosan (TPP-chitosan) microspheres by the spray-drying method at different manufacturing conditions. Manufacturing parameters (inlet temperature, liquid flow rate, chitosan concentratio...

journal_title：Journal of microencapsulation

authors： Desai KG,Park HJ

更新日期：2006-02-01 00:00:00

abstract：:Hyaluronidase is a protein whose enzymatic activity is successfully employed in extravasation therapy. Taking into account that several proteins (e.g. gelatin and albumin) have been employed as natural polymers for the preparation of microspheres, this work approaches a comprehensive investigation on hyaluronidase inj...

journal_title：Journal of microencapsulation

authors： Modena T,Conti B,Genta I,Pauanetto F,Tira ME,Sini P,Gazzaniga A

更新日期：1998-01-01 00:00:00

abstract：:Chlorogenic acid (CA) is a natural compound used as an antioxidant in the preparation of food, drugs, and cosmetics. Due to their low stability and bioavailability, many researchers have studied the encapsulation of CA in various delivery colloidal systems. The aim of this study was to evaluate the stability of water-...

journal_title：Journal of microencapsulation

authors： Dima C,Dima S

更新日期：2018-09-01 00:00:00

abstract：:Redox-responsive magnetic protein microcapsules with Fe3O4 magnetic nanoparticles (MNPs) encapsulated inside have been obtained using a facile, cost-effective and fast sonochemical method from hen egg white proteins. Such prepared redox-responsive magnetic hen egg white protein microcapsules (MHEWPMCs) could be easily...

journal_title：Journal of microencapsulation

authors： Zhong S,Cui X,Tian F

更新日期：2015-01-01 00:00:00

abstract：:In the previous report, microencapsulation of lipase employing a (w/o)/w multiple phase emulsion technique, with 2:1 polystyrene (PS)-SBR mixture being used as a wall material, was proposed. Catalysis of the encapsulated enzyme was investigated, and the hydrolysis of triacetin (triglyceride of acetic acid) was success...

journal_title：Journal of microencapsulation

authors： Iso M,Shirahase T,Hanamura S,Urushiyama S,Omi S

更新日期：1989-07-01 00:00:00

abstract：:Provision and maintenance of adequate concentrations of antibiotics at infection sites is very important in treating highly resistant infections. For diseases like implant related osteomyelitis (IRO) it is best to provide this locally via implanted drug formulations, as systemic administration of the antibiotic may no...

journal_title：Journal of microencapsulation

authors： Gurselt I,Yagmurlu F,Korkusuz F,Hasirci V

更新日期：2002-03-01 00:00:00

abstract：:The development of microparticulate food particles for marine suspension-feeders is discussed with respect to the difficulties of nutrient delivery in the aquatic environment and to feeding and digestion in crustacea and bivalve molluscs. Loss of nutrients from particles suspended in seawater must be minimized by eith...

journal_title：Journal of microencapsulation

authors： Langdon CJ,Levine DM,Jones DA

更新日期：1985-01-01 00:00:00

abstract：:In this work we have examined the ability of various lipopolyplexes to deliver genes into liver cancer cells. We evaluated different parameters such as the protocol of preparation, the lipid/DNA molar ratio, and the molecular weight and type of PEI, to optimize the formulation to achieve high transfection activity. Ou...

journal_title：Journal of microencapsulation

authors： Tros de Ilarduya C,García L,Düzgünes N

更新日期：2010-01-01 00:00:00

abstract：:An overview of biodegradable and biocompatible microcapsules and microspheres loaded with neuroactive substances, or cells producing neuroactive substances, and their role as drug delivery systems (DDS) for drug administration to the central nervous system (CNS) is given. In addition, closely related systems are also ...

journal_title：Journal of microencapsulation

authors： Filipović-Grcić J,Maysinger D,Jalsenjak I

更新日期：1995-07-01 00:00:00

abstract：:Microencapsulation is almost exclusively performed in batch processes. With today's chemistry increasingly performed in flow reactors, this work aims to realise a continuous reactor setup for the encapsulation of an ester with a polyuria (PU) shell. The generation of an emulsion template is performed in a recirculatio...

journal_title：Journal of microencapsulation

authors： Gobert SRL,Segers M,Luca S,Teixeira RFA,Kuhn S,Braeken L,Thomassen LCJ

更新日期：2019-06-01 00:00:00

abstract：:Magnetic and pH-responsive chitosan microcapsules (MPRCMCs) were prepared by a simple sonochemical method. Superparamagnetic oleic acid modified Fe3O4 nanoparticles (OA-Fe3O4 NPs) and hydrophobic drugs could be directly loaded into MPRCMCs during sonication. The obtained microcapsules had a well-defined spherical morp...

journal_title：Journal of microencapsulation

authors： Xu F,Zhao T,Wang S,Liu S,Yang T,Li Z,Wang H,Cui X

更新日期：2016-01-01 00:00:00

abstract：:In this study microspheres of diclofenac sodium, an anti-inflammatory agent, were prepared by utilizing a natural polysaccharide, chitosan-H. The objective of this investigation was to sustain the action of diclofenac sodium and to show the effect of various conditions on release kinetics. For this reason factorial de...

journal_title：Journal of microencapsulation

authors： Açikgöz M,Kaş HS,Orman M,Hincal AA

更新日期：1996-03-01 00:00:00

abstract：:Biodegradable hollow capsules filled with fluorescently labelled bovine serum albumin (BSA) as a model drug were prepared via layer-by-layer (LbL) self-assembly of type-I collagen (COL) and hyaluronic acid (HA) using calcium carbonate micro-particles and co-precipitation method. Capsules loaded with fluorescein isothi...

journal_title：Journal of microencapsulation

authors： Sousa F,Kreft O,Sukhorukov GB,Möhwald H,Kokol V

更新日期：2014-01-01 00:00:00

abstract：:Polyelectrolyte complexes (PEC) provide new opportunities for controlled release system of drugs, and have potentials to address challenges on the way to effective oral insulin delivery. Here, an innovative pH-sensitive PEC for insulin oral administration was developed, which was formed by self-assembly of two opposit...

journal_title：Journal of microencapsulation

authors： Chen T,Li S,Zhu W,Liang Z,Zeng Q

更新日期：2019-01-01 00:00:00

abstract：:Liposomes containing Isovist were prepared by controlled detergent dialysis as well as by reverse phase evaporation. After preparation these liposomes were lyophilized and then submitted to sterilization by ethylene oxide. Prior to lyophilization, trehalose was added as a protective agent to preserve the size of the l...

journal_title：Journal of microencapsulation

authors： Ratz H,Freise J,Magerstedt P,Schaper A,Preugschat W,Keyser D

更新日期：1989-10-01 00:00:00

abstract：:Different classes of excipients with potential for use in the design of novel pelletized formulations manufactured by extrusion-spheronization were examined using factorial experiments. Among the various silicates examined in a model mix with microcrystalline cellulose and lactose wetted with water, kaolin, talc and V...

journal_title：Journal of microencapsulation

authors： Law MF,Deasy PB

更新日期：1997-09-01 00:00:00

abstract：:This study explored a liquid phase coating technique to produce polymethyl methacrylate (PMMA)-coated alginate microspheres. Alginate microspheres with a mean diameter of 85.6 microm were prepared using an emulsification method. The alginate microspheres, as cores, were then coated with different types of PMMA by a li...

journal_title：Journal of microencapsulation

authors： Chan LW,Liu X,Heng PW

更新日期：2005-12-01 00:00:00

abstract：:In this study, ethylcellulose and acrylate-methacrylate copolymer (Eudragit RL 100, Eudragit RS 100) membranes were prepared by using appropriate types and amounts of plasticizers. Thirty percent and 20% of triacetin based on polymer weight were found to be appropriate plasticizers for ethylcellulose membranes and acr...

journal_title：Journal of microencapsulation

authors： Nimmannit U,Suwanpatra N

更新日期：1996-11-01 00:00:00

abstract：:Encapsulated vitro-derived apical buds of M.26 apple rootstock (Malus pumila Mill) can be employed for the formation of the synthetic seed. Satisfactory levels of conversion (plantlets from synthetic seed) can be achieved if there are adequate (i) rooting induction treatment, (ii) protocol of encapsulation, and (iii) ...

journal_title：Journal of microencapsulation

authors： Micheli M,Pellegrino S,Piccioni E,Standardi A

更新日期：2002-05-01 00:00:00

abstract：PURPOSE:To develop a stable and reproducible modified release pellet formulation containing ibuprofen. METHODS:Using extrusion-spheronization technology to produce pellets. RESULTS:The percentage yield, size distribution and overall pellet shape within the desired size range of 1000-1400 microm was found to be depend...

journal_title：Journal of microencapsulation

authors： Lutchman D,Dangor CM,Perumal D

更新日期：2005-09-01 00:00:00

abstract：:A new material for the microencapsulation of biological systems was discovered and characterized with regards to the effects of reaction conditions on product yield. By using poly(cyanoacrylate ester), membrane microcapsules were produced with sufficient strength and porosity to be effective in a process environment f...

journal_title：Journal of microencapsulation

authors： Holl RJ,Chambers RP

更新日期：2002-11-01 00:00:00

abstract：:Atomic force microscopy (AFM) is recognized a suitable and powerful technique for surface and morphological analysis. Even if until now this technique has not been frequently used in the pharmaceutical field, it can contribute to an accurate morphologic characterization of microspheres and nanospheres. In this work, a...

journal_title：Journal of microencapsulation

authors： Dorati R,Patrini M,Perugini P,Pavanetto F,Stella A,Modena T,Genta I,Conti B

更新日期：2006-03-01 00:00:00

abstract：:Drug release from gelatin/poly(acrylic acid) oxprenolol-loaded microspheres has been evaluated using an in situ sink immersion method and a wetting method. The kinetics of drug release were analysed by applying the empirical exponential equation and by the calculation of the approximate contribution of the diffusional...

journal_title：Journal of microencapsulation

authors： Leucuta SE,Ponchel G,Duchêne D

更新日期：1997-07-01 00:00:00

abstract：:In this study, the anticancer activities of two siRNA carriers were compared using a human lung adenocarcinoma epithelial cell line (A549). Firstly, poly(styrene)-graft-poly(linoleic acid) (PS-g-PLina) and poly(styrene)-graft-poly(linoleic acid)-graft-poly(ethylene glycol) (PS-g-PLina-g-PEG) graft copolymers were synt...

journal_title：Journal of microencapsulation

authors： Anilmis NM,Kara G,Kilicay E,Hazer B,Denkbas EB

更新日期：2019-11-01 00:00:00

abstract：:Gelatin/gum arabic (GA) microcapsules were prepared by a convenient one step complex coacervation, in which TiO2 nanoparticles modified by stearic acid (SA) and homodispersed in tetrachloroethylene (TCE) were encapsulated. The modified TiO2 was characterized by Fourier transform infrared spectroscopy (FT-IR), dynamic ...

journal_title：Journal of microencapsulation

authors： Wang DW,Zhao XP

更新日期：2009-02-01 00:00:00

abstract：:Insulin-loaded solid lipid nanoparticles (SLN), obtained by the solvent-in-water emulsion-diffusion technique, were produced using isovaleric acid (IVA) as organic phase, glyceryl mono-stearate (GMS) as lipid, soy lecithin and sodium taurodeoxycholate (TDC) as emulsifiers. IVA, a partially water-miscible solvent with ...

journal_title：Journal of microencapsulation

authors： Battaglia L,Trotta M,Gallarate M,Carlotti ME,Zara GP,Bargoni A

更新日期：2007-11-01 00:00:00

abstract：:Aims: The study was carried out to synthesise and characterise the chitosan-encapsulated genistein (CHI-En/Gen) and determine its anti-cancer and anti-angiogenic properties.Methods: The cytotoxic and anti-angiogenic activity of CHI-En/Gen was performed using MTT and chorioallantoic membrane assay. The molecular action...

journal_title：Journal of microencapsulation

authors： Rahmani F,Karimi E,Oskoueian E

更新日期：2020-06-01 00:00:00

abstract：:Proliposomes of ibuprofen were successfully prepared using effervescent granules as solid carriers of dried phospholipids along with other lipids (soyabean lecithin, stearylamine and cholesterol). Liposomes of regular size with uniform size distribution resulted when proliposomal formulations were hydrated under the e...

journal_title：Journal of microencapsulation

authors： Katare OP,Vyas SP,Dixit VK

更新日期：1990-10-01 00:00:00

abstract：:Protamine-oligonucleotide nanoparticles represent effective colloidal drug carriers for antisense phosphorothioate oligonucleotides (PTO). This study describes improvements in particle preparation and the physicochemical properties of the complexes prepared. The influence of component concentrations, length of the PTO...

journal_title：Journal of microencapsulation

authors： Lochmann D,Vogel V,Weyermann J,Dinauer N,von Briesen H,Kreuter J,Schubert D,Zimmer A

更新日期：2004-09-01 00:00:00