Physico-chemical characterisation, cytotoxic activity, and biocompatibility studies of tamoxifen-loaded solid lipid nanoparticles prepared via a temperature-modulated solidification method.

abstract：:Optimum conditions for the preparation of non-magnetic and magnetic microspheres of albumin-globulin mix (alglomix) containing mefenamic acid have been standardized. The effect of various parameters has been investigated with regard to the appearance, yield, drug content and encapsulation efficiency. The physicochemic...

journal_title：Journal of microencapsulation

authors： Lalla JK,Ahuja PL

更新日期：1991-01-01 00:00:00

abstract：:To overcome the recurrence problem in bladder tumours; nanoparticles with positive surface charge may improve interaction with biological membranes for intravesical administration. The aim of this study was to design, develop and evaluate (in vitro-in vivo) cationic nanoparticles based on chitosan, poly-L-lysine or po...

journal_title：Journal of microencapsulation

authors： Erdoğar N,Iskit AB,Mungan NA,Bilensoy E

更新日期：2012-01-01 00:00:00

abstract：:An extrusion-based encapsulation process has been developed for making salt grain-sized iron premix for salt fortification. The first step of extrusion agglomeration process has been studied and reported previously. The focus of this study is on the optimisation of the colour-masking and polymer coating steps. Several...

journal_title：Journal of microencapsulation

authors： Yadava D,Olive Li Y,Diosady LL,Wesley AS

更新日期：2012-01-01 00:00:00

abstract：:In ophthalmic drug delivery, a major problem is retaining an adequate concentration of a therapeutic agent in the pre-corneal area. Polycarboxylic acid carriers such as polyacrylic acid and polyitaconic acid in sub-colloidal, nanoparticulate hydrogel form have a strong potential for sustained release of a drug in ocul...

journal_title：Journal of microencapsulation

authors： De TK,Bergey EJ,Chung SJ,Rodman DJ,Bharali DJ,Prasad PN

更新日期：2004-12-01 00:00:00

abstract：:Encapsulated vitro-derived apical buds of M.26 apple rootstock (Malus pumila Mill) can be employed for the formation of the synthetic seed. Satisfactory levels of conversion (plantlets from synthetic seed) can be achieved if there are adequate (i) rooting induction treatment, (ii) protocol of encapsulation, and (iii) ...

journal_title：Journal of microencapsulation

authors： Micheli M,Pellegrino S,Piccioni E,Standardi A

更新日期：2002-05-01 00:00:00

abstract：:Since 1978 we have prepared microencapsulated insecticides by complex coacervation and interfacial polymerization for household insect pest control, fenthion being the main core element. A series of tests have been conducted against mosquitoes (Culex pipiens quinquefasciatus), cockroaches (Periplaneta americana) and b...

journal_title：Journal of microencapsulation

authors： Gao YT,Shen PY,Wang BH,Lü SD,Huang GC,Ho LS

更新日期：1984-10-01 00:00:00

abstract：:Protamine-oligonucleotide nanoparticles represent effective colloidal drug carriers for antisense phosphorothioate oligonucleotides (PTO). This study describes improvements in particle preparation and the physicochemical properties of the complexes prepared. The influence of component concentrations, length of the PTO...

journal_title：Journal of microencapsulation

authors： Lochmann D,Vogel V,Weyermann J,Dinauer N,von Briesen H,Kreuter J,Schubert D,Zimmer A

更新日期：2004-09-01 00:00:00

abstract：:Background: Lavender oil consists of around 100 components and is susceptible to volatilisation and degradation reactions. Aim: Microencapsulate lavender oil by spray drying using a biocompatible polymeric blend of gum acacia and maltodextrin to protect the oil components. Effect of total polymer content, oil loading,...

journal_title：Journal of microencapsulation

authors： Burhan AM,Abdel-Hamid SM,Soliman ME,Sammour OA

更新日期：2019-05-01 00:00:00

abstract：:This work aimed to investigate the potential effect of cyclodextrin encapsulation on intrinsic ability of daidzein (DAD) and genistein (GEN) to inhibit the glycosaminoglycan (GAG) synthesis in fibroblasts originating from patients with mucopolysaccharidosis (MPS), type II and III. DAD or GEN encapsulation with either ...

journal_title：Journal of microencapsulation

authors： Fumić B,Jablan J,Cinčić D,Zovko Končić M,Jug M

更新日期：2018-01-01 00:00:00

abstract：:Palmatine (PM) is a potent anti-infective agent used to treat eye diseases. However, PM is less effective for ocular application due to short residence time within the eyes. This study aimed to develop a cationic lipid emulsions (CLEs) for ophthalmic delivery of PM and evaluate its suitability in infection treatment. ...

journal_title：Journal of microencapsulation

authors： Yin J,Xiang C,Lu G

更新日期：2016-12-01 00:00:00

abstract：:Microcapsules were prepared through an interfacial cross-linking process using terephthaloylchloride and applied to mixtures of a protein (human serum albumin or gelatin) and a polysaccharide. Their properties were compared with those of microcapsules prepared from the protein alone. Morphological characteristics of m...

journal_title：Journal of microencapsulation

authors： Levy MC,Andry MC

更新日期：1991-07-01 00:00:00

abstract：:The soft microcapsules containing eucalyptus oil, ubiquinone and the fine water droplets could be prepared with interfacial dehydration reaction between hydroxy methyl cellulose and tannic acid using the water-in-oil-in-water type multiple (W/O)/W emulsion. The diameters of the microcapsules and the content and the mi...

journal_title：Journal of microencapsulation

authors： Taguchi Y,Suzuki T,Saito N,Yokoyama H,Tanaka M

更新日期：2017-12-01 00:00:00

abstract：:Sequential interpenetrating networks of poly(methacrylic acid) and poly(vinyl alcohol) have been prepared and cross-linked with glutaraldehyde to obtain pH sensitive microspheres by a water-in-oil emulsification method. Microspheres have been used to deliver the chosen model anti-inflammatory drug viz., ibuprofen to t...

journal_title：Journal of microencapsulation

authors： Mundargi RC,Patil SA,Kulkarni PV,Mallikarjuna NN,Aminabhavi TM

更新日期：2008-06-01 00:00:00

abstract：:Low molecular weight heparin (LMWH)-loaded flexible liposomes (flexosomes) were formulated for transdermal delivery, and their physicochemical and pharmacokinetic parameters were compared with LMWH-loaded ethosomes. Flexosomes had similar particle size compared with ethosomes, but their deformability was higher than t...

journal_title：Journal of microencapsulation

authors： Song YK,Hyun SY,Kim HT,Kim CK,Oh JM

更新日期：2011-01-01 00:00:00

abstract：:Anal fissure is common and painful disease of anorectum. In this study, microparticles containing nifedipine and lidocaine HCl were prepared by spray drying and applied to bio-degradable and bio-stable tampons. Characterization of microparticles was determined by visual analyses, mass yield, particle size measurement,...

journal_title：Journal of microencapsulation

authors： Sarıışık AM,Karavana SY,Türkoğlu GC,Rençber S,Önder T

更新日期：2017-12-01 00:00:00

abstract：:In this work we have examined the ability of various lipopolyplexes to deliver genes into liver cancer cells. We evaluated different parameters such as the protocol of preparation, the lipid/DNA molar ratio, and the molecular weight and type of PEI, to optimize the formulation to achieve high transfection activity. Ou...

journal_title：Journal of microencapsulation

authors： Tros de Ilarduya C,García L,Düzgünes N

更新日期：2010-01-01 00:00:00

abstract：:Drug-free polylactic acid (PLA) microspheres were prepared by an emulsification-solvent evaporation technique using different types of protective colloids. The influence of five types of hydrophilic prolymers (polysaccharides, proteins, synthetic cellulose derivatives, synthetic nonionic polymers and surfactants) on t...

journal_title：Journal of microencapsulation

authors： Lin SY,Chen KS,Teng HH

更新日期：1998-05-01 00:00:00

abstract：:Hyaluronidase is a protein whose enzymatic activity is successfully employed in extravasation therapy. Taking into account that several proteins (e.g. gelatin and albumin) have been employed as natural polymers for the preparation of microspheres, this work approaches a comprehensive investigation on hyaluronidase inj...

journal_title：Journal of microencapsulation

authors： Modena T,Conti B,Genta I,Pauanetto F,Tira ME,Sini P,Gazzaniga A

更新日期：1998-01-01 00:00:00

abstract：:Polylactide (PLA) and polylactide-co-glycolide (PLGA) particles entrapping rotavirus (strain SA11) were formulated using a solvent evaporation technique. To minimize denaturation of viral antigen during the emulsification process, serum albumin was used as a stabilizer. Use of NaHCO(3) and sucrose during the primary e...

journal_title：Journal of microencapsulation

authors： Nayak B,Panda AK,Ray P,Ray AR

更新日期：2009-03-01 00:00:00

abstract：:The objective of this study was to prepare floating theophylline microspheres with zero order release profiles for use as buoyant reservoirs with increased retention time in the stomach. The microspheres were prepared by a modified emulsion-solvent evaporation method using a polymer mixture of cellulose acetate butyra...

journal_title：Journal of microencapsulation

authors： Stithit S,Chen W,Price JC

更新日期：1998-11-01 00:00:00

abstract：:A new material for the microencapsulation of biological systems was discovered and characterized with regards to the effects of reaction conditions on product yield. By using poly(cyanoacrylate ester), membrane microcapsules were produced with sufficient strength and porosity to be effective in a process environment f...

journal_title：Journal of microencapsulation

authors： Holl RJ,Chambers RP

更新日期：2002-11-01 00:00:00

abstract：:This study focuses on development and in vitro characterisation of a nasal delivery system based on uncoated or chitosan-coated solid lipid microparticles (SLMs) containing resveratrol, a natural anti-inflammatory molecule, as an effective alternative to the conventional steroidal drugs. The physico-chemical character...

journal_title：Journal of microencapsulation

authors： Martignoni I,Trotta V,Lee WH,Loo CY,Pozzoli M,Young PM,Scalia S,Traini D

更新日期：2016-12-01 00:00:00

abstract：:The aim of this study was to investigate how glass transition temperature (Tg) influenced polymer microsphere formation and degradation of three chemically, similar novel salicylatebased poly(anhydride-esters): poly[1,6-bis(o-carboxyphenoxy)hexanoate] (CPH), Tg = 59 degrees C; poly[1,8-bis(o-carboxyphenoxy)octanoate] ...

journal_title：Journal of microencapsulation

authors： Yeagy BA,Prudencio A,Schmeltzer RC,Uhrich KE,Cook TJ

更新日期：2006-09-01 00:00:00

abstract：:Cross-linked albumin microcapsules were prepared, using a polycondensation interfacial process. Doxorubicin was incorporated in these microcapsules by simple adsorption from aqueous solution. Increasing the extent of cross-linkage of the microcapsule walls by either increasing the cross-linking agent concentration or ...

journal_title：Journal of microencapsulation

authors： Sawaya A,Fickat R,Benoit JP,Puisieux F,Benita S

更新日期：1988-07-01 00:00:00

abstract：:The purpose of present research work was to develop mucoadhesive microspheres for nasal delivery with the aim to avoid hepatic first-pass metabolism, improve therapeutic efficacy and enhance residence time. For the treatment of migraine, hydroxypropyl methylcellulose (HPMC) K4M and K15M based microspheres containing s...

journal_title：Journal of microencapsulation

authors： Jain SA,Chauk DS,Mahajan HS,Tekade AR,Gattani SG

更新日期：2009-12-01 00:00:00

abstract：:Nanoparticles and microspheres made from human serum albumin are biodegradable and, as a physiological material, less cytocidal than cyanoacrylates. Therefore, they should be a suitable carrier system for targeting drugs into cells of the mononuclear phagocyte system. Nevertheless, the process of phagocytic uptake and...

journal_title：Journal of microencapsulation

authors： Schäfer V,von Briesen H,Rübsamen-Waigmann H,Steffan AM,Royer C,Kreuter J

更新日期：1994-05-01 00:00:00

abstract：:Nanoparticles prepared of human serum albumin (HSA) represent promising carriers for drug delivery. Desolvating procedure is a common method to obtain protein-based particles. However process parameters have a great influence on size, size distribution and particle yield of the resulting formulation. Therefore, it is ...

journal_title：Journal of microencapsulation

authors： Storp Bv,Engel A,Boeker A,Ploeger M,Langer K

更新日期：2012-01-01 00:00:00

abstract：:The effects of different loading procedures of magnetic nanoparticles (MNs) on the structure and physicochemical properties of cisplatin magnetic liposomes were investigated by X-ray diffraction, infrared spectroscopy, transmission electron microscopy, and fluorescence spectroscopy. 1, 2-Dipalmitoyl-sn-glycero-3-Phosp...

journal_title：Journal of microencapsulation

authors： Wang L,Yang CQ,Wang J

更新日期：2012-01-01 00:00:00

abstract：:We studied a model system of controlled drug release using beta-carotene and κ-carrageenan/NaCMC hydrogel as a drug and a device, respectively. Different concentrations of genipin were added to crosslink the beta-carotene loaded beads by using the dripping method. Results have shown that the cross-linked beads possess...

journal_title：Journal of microencapsulation

authors： Hezaveh H,Muhamad II,Noshadi I,Shu Fen L,Ngadi N

更新日期：2012-01-01 00:00:00

abstract：:N-lauroyl chitosan (NLCS) conjugates with different degrees of substitution (DS) of lauroyl group were synthesized and used to prepare surface modified poly(lactic-co-glycolic) acid (NLCS-PLGA) nanoparticles via hydrophobic interaction and ionic bond force. NLCS-PLGA nanoparticles had spherical shape with shell-core s...

journal_title：Journal of microencapsulation

authors： Li J,Zhou P,Wang Y,Chen H,Zhang C,Li R,Yang X,Wang Y

更新日期：2014-01-01 00:00:00