Preparation and characterization of vitamin-12 loaded biodegradable pH-sensitive microgels.

abstract：:The real issue in the development of oral controlled release dosage forms is not just to prolong the delivery of drugs but also to prolong the presence of dosage forms in the stomach in order to improve the bioavailability of drugs with a 'narrow absorption window'. In the present study, an anti-ulcer drug, ranitidine...

journal_title：Journal of microencapsulation

authors： Mastiholimath VS,Dandagi PM,Gadad AP,Mathews R,Kulkarni AR

更新日期：2008-08-01 00:00:00

abstract：:Microencapsulation aims to protect polyunsaturated fatty acids against oxidation by embedding oil droplets in a solid matrix. The effect of the oil droplet size on the oxidation was evaluated under consideration of the non-encapsulated oil and the powder particle size. An O/W emulsion (1.6%(w/w) soy protein; 30.4%(w/w...

journal_title：Journal of microencapsulation

authors： Linke A,Hinrichs J,Kohlus R

更新日期：2020-03-01 00:00:00

abstract：:Regular spherical microspheres of 220-260 microns average size have been prepared from vinylpyrrolidone/vinylacetate copolymer using a solvent evaporation method. Griseofulvin has been incorporated into these microspheres and its physical characterization has been carried out by differential scanning calorimetry (DSC)...

journal_title：Journal of microencapsulation

authors： Vojnovic D,Rubessa F,Bogataj M,Mrhar A

更新日期：1993-01-01 00:00:00

abstract：:Artificial chylomicron remnants were investigated as a new drug carrier system for the targeting of hepatic parenchymal cells. The emulsions presented here are similar in particle size and composition to natural lipoproteins. The preparations contained triolein, phospholipid, cholesterol and cholesteryl oleate. Egg yo...

journal_title：Journal of microencapsulation

authors： Vuaridel-Bonanomi ES,Weder HG

更新日期：1991-04-01 00:00:00

abstract：:The effect of lecithin and starch on viability of alginate encapsulated probiotics was determined at different temperatures. Probiotic organisms (1% v/v>10Log CFU ml(-1)) were encapsulated using alginate (2% w/v), gelatinized starches (2% w/v) and lecithin (0-4% w/v) and stored in sealed containers at 4, 23 and 37 deg...

journal_title：Journal of microencapsulation

authors： Donthidi AR,Tester RF,Aidoo KE

更新日期：2010-01-01 00:00:00

abstract：:The purpose of this study was to design and characterise an oral mucoadhesive micellar drug carrier. In this regard, a mucoadhesive hydrophobic cationic aminocellulose was easily synthesised under mild homogeneous conditions with high yield. The cellulose derivative resulted in strongly improved mucoadhesive propertie...

journal_title：Journal of microencapsulation

authors： Songsurang K,Siraleartmukul K,Muangsin N

更新日期：2015-01-01 00:00:00

abstract：:The purpose of this study was the preparation, optimisation and in vitro characterisation of PHBV and PLGA blend nanoparticles (NPs) for prolonged delivery of Teriparatide. Double emulsion solvent evaporation technique was employed for the fabrication of NPs. The nanoformulation was optimised using the Box-Behnken met...

journal_title：Journal of microencapsulation

authors： Bahari Javan N,Rezaie Shirmard L,Jafary Omid N,Akbari Javar H,Rafiee Tehrani M,Abedin Dorkoosh F

更新日期：2016-08-01 00:00:00

abstract：:Anal fissure is common and painful disease of anorectum. In this study, microparticles containing nifedipine and lidocaine HCl were prepared by spray drying and applied to bio-degradable and bio-stable tampons. Characterization of microparticles was determined by visual analyses, mass yield, particle size measurement,...

journal_title：Journal of microencapsulation

authors： Sarıışık AM,Karavana SY,Türkoğlu GC,Rençber S,Önder T

更新日期：2017-12-01 00:00:00

abstract：:For slow release of tea tree oil (TTO), TTO were encapsulated by urea-formaldehyde (UF) resin via in situ polymerisation. The effects of curing time and drying condition on particle size, and TTO loading of the TTO/UF microcapsules were investigated. The results indicated that TTO/UF resin microcapsules with curing ti...

journal_title：Journal of microencapsulation

authors： Huang Q,Gong S,Han W,Chen Y,Shu X

更新日期：2020-06-01 00:00:00

abstract：:The factors influencing the encapsulation of azathioprine (AZA) into liposomes were investigated to find out the conditions for its optimal entrapment. Similar studies for comparison were also carried out on 6-mercaptopurine (6-MP), of which AZA is a prodrug. AZA and also 6-MP show higher encapsulation efficiencies in...

journal_title：Journal of microencapsulation

authors： Gulati M,Grover M,Singh M,Singh S

更新日期：1998-07-01 00:00:00

abstract：:This work investigated the means for the efficient encapsulation of muramyl dipeptide (MDP) in poly(epsilon-caprolactone) (PCL) microparticles (MP) by a solvent evaporation method in order to optimize the effect of the adjuvant for oral immunization. Therefore, the influence of MDP concentration in the inner aqueous p...

journal_title：Journal of microencapsulation

authors： Youan BB,Benoit MA,Rollmann B,Riveau G,Gillard J

更新日期：1999-09-01 00:00:00

abstract：:Drug release from gelatin/poly(acrylic acid) oxprenolol-loaded microspheres has been evaluated using an in situ sink immersion method and a wetting method. The kinetics of drug release were analysed by applying the empirical exponential equation and by the calculation of the approximate contribution of the diffusional...

journal_title：Journal of microencapsulation

authors： Leucuta SE,Ponchel G,Duchêne D

更新日期：1997-07-01 00:00:00

abstract：:In ophthalmic drug delivery, a major problem is retaining an adequate concentration of a therapeutic agent in the pre-corneal area. Polycarboxylic acid carriers such as polyacrylic acid and polyitaconic acid in sub-colloidal, nanoparticulate hydrogel form have a strong potential for sustained release of a drug in ocul...

journal_title：Journal of microencapsulation

authors： De TK,Bergey EJ,Chung SJ,Rodman DJ,Bharali DJ,Prasad PN

更新日期：2004-12-01 00:00:00

abstract：:Sub-100-nm nanoparticles were prepared from beta-lactoglobulin (BLG) with a narrow size distribution by a desolvation method using glutaraldehyde for cross-linking. With pre-heating of the BLG solution to 60 degrees C and subsequent pH readjustment to 9.0, nanoparticles of 59 +/- 5 nm were obtained with improved unifo...

journal_title：Journal of microencapsulation

authors： Ko S,Gunasekaran S

更新日期：2006-12-01 00:00:00

abstract：:Microencapsulation is almost exclusively performed in batch processes. With today's chemistry increasingly performed in flow reactors, this work aims to realise a continuous reactor setup for the encapsulation of an ester with a polyuria (PU) shell. The generation of an emulsion template is performed in a recirculatio...

journal_title：Journal of microencapsulation

authors： Gobert SRL,Segers M,Luca S,Teixeira RFA,Kuhn S,Braeken L,Thomassen LCJ

更新日期：2019-06-01 00:00:00

abstract：:The diblock copolymers based on PBLG and PEO (GE) were synthesized and characterized. Nanoparticles showed spherical shape from the observations of TEM and approved core-shell structure. Drug contents were increased with use of higher initial drug concentration and higher Mw of GE. Nifedipine (NFD) release rate was sl...

journal_title：Journal of microencapsulation

authors： Jeong YI,Sun HS,Shim YH,Kim C,Park SH,Choi KC,Cho CS

更新日期：2004-06-01 00:00:00

abstract：:To improve poor water solubility of cyclosporine A (CsA), hydroxypropyl-beta-cyclodextrin (HPβCD) was incorporated into the nanoparticle formulation. Solid complexes of CsA with HPβCD in different ratios were prepared by the kneading method. CsA containing alone or in combination with HPβCD in poly-lactide-co-glycolid...

journal_title：Journal of microencapsulation

authors： Aksungur P,Demirbilek M,Denkbaş EB,Unlü N

更新日期：2012-01-01 00:00:00

abstract：CONTEXT:Flavonoids show promising anticancer potential but it is limited due to poor solubility. OBJECTIVE:The present investigation was to prepare Chrysin-Phospholipid complex loaded solid lipid nanoparticles (Ch-PC-SLNs) for improving its encapsulation as compared to that of Chrysin loaded SLNs (Ch-SLNs) and evaluat...

journal_title：Journal of microencapsulation

authors： Komath S,Garg A,Wahajuddin M

更新日期：2018-09-01 00:00:00

abstract：:Abietic acid was isolated from rosin N Grade (ISI) by a simple process and the product was further standardized. Sulphadiazine microcapsules were prepared by the solvent evaporation technique, using abietic acid as a wall-forming material. Discrete, spherical and free-flowing microcapsules were obtained by phase separ...

journal_title：Journal of microencapsulation

authors： Puranik PK,Manekar NC,Dorle AK

更新日期：1992-10-01 00:00:00

abstract：:This article describes the physicochemical properties of chitosan-coated liposomes containing skin-protecting agents, coenzyme Q10 and alpha-lipoic acid (CCAL). CCAL had a spherical shell-core structure and liposomes inverted the surface charge from negative to positive after coating with chitosan. Compared with the u...

journal_title：Journal of microencapsulation

authors： Zhao GD,Sun R,Ni SL,Xia Q

更新日期：2015-01-01 00:00:00

abstract：:This study optimized and evaluated the conditions for surface coating of microspheres using a spray-dryer. Four formulations of Bromophenol blue (BPB)-loaded albumin microspheres were prepared using a spray-dryer, cross-linked at different concentrations and time periods. One of the optimized formulations with the des...

journal_title：Journal of microencapsulation

authors： Bejugam NK,Uddin AN,Gayakwad SG,D'Souza MJ

更新日期：2008-12-01 00:00:00

abstract：:Nanoencapsulation by spray drying was performed to protect and preserve antioxidant rich dietary polyphenols from green coffee beans. Nano-encapsulation of green coffee was done using maltodextrin as wall material. The nanoparticles were further characterised by zetasizer, differential scanning colorimetry, X-ray diff...

journal_title：Journal of microencapsulation

authors： Desai NM,Gilbert Stanley J,Murthy PS

更新日期：2020-01-01 00:00:00

abstract：:The size dependent and size independent contributions to the mechanical properties of poly(ethyleneglycol) microspheres with encapsulated air, made for medical ultrasound imaging, have been studied. A relation between the size of microspheres in a reference group and their acoustic attenuation efficacy was derived by ...

journal_title：Journal of microencapsulation

authors： Dyrstad K,Sontum PC,Hoff L

更新日期：2000-05-01 00:00:00

abstract：:Polylactic acid microcapsules containing randomly distributed hydrocortisone particles were prepared. The rate of release of hydrocortisone from the microcapsules in pH 7.4 phosphate buffer was found to be largely increased by the presence of polysorbate 80, cetylpyridinium chloride, or aerosol OT in the dissolution m...

journal_title：Journal of microencapsulation

authors： Leelarasamee N,Howard SA,Ma JK

更新日期：1988-01-01 00:00:00

abstract：:Secretory leukocyte protease inhibitor (SLPI) is an endogenous serine protease inhibitor that protects the lungs from excessive tissue damage caused by leukocyte proteases released during inflammation. Recombinant SLPI (rSLPI) has shown potential as a treatment for inflammatory lung conditions. To date, its clinical a...

journal_title：Journal of microencapsulation

authors： Gibbons AM,McElvaney NG,Taggart CC,Cryan SA

更新日期：2009-09-01 00:00:00

abstract：:Silica gel microspheres are ideal materials for bioencapsulation due to their mechanical properties, biocompatibility, and stability. Encapsulated cells are isolated from the environment and protected from predators, changes in pH, and osmotic stress. However methods for the production of silica gel microspheres suita...

journal_title：Journal of microencapsulation

authors： Benson JJ,Wackett LP,Aksan A

更新日期：2016-08-01 00:00:00

abstract：:This study focuses on development and in vitro characterisation of a nasal delivery system based on uncoated or chitosan-coated solid lipid microparticles (SLMs) containing resveratrol, a natural anti-inflammatory molecule, as an effective alternative to the conventional steroidal drugs. The physico-chemical character...

journal_title：Journal of microencapsulation

authors： Martignoni I,Trotta V,Lee WH,Loo CY,Pozzoli M,Young PM,Scalia S,Traini D

更新日期：2016-12-01 00:00:00

abstract：:The present research work was aimed at development and optimization of alginate mucoadhesive microspheres of carvedilol for nasal delivery to avoid first pass metabolism and to improve the therapeutic efficacy in the treatment of hypertension and angina pectoris. The microspheres were prepared by a water-in-oil (w/o) ...

journal_title：Journal of microencapsulation

authors： Patil SB,Sawant KK

更新日期：2009-08-01 00:00:00

abstract：:This work demonstrates Box-Behnken design (BBD)'s capability in exploring scientific principles governing a process, different from its use in process optimisation. We have investigated nanoprecipitation (NP) of temozolomide with polycaprolactone. Five factors, surfactant, stirring speed (SS), dropping rate (DR), phas...

journal_title：Journal of microencapsulation

authors： Singh Y,Ojha P,Srivastava M,Chourasia MK

更新日期：2015-01-01 00:00:00

abstract：:Eudragit RS microspheres containing verapamil HCl for oral use were prepared using three different dispersing agents: aluminium tristearate, magnesium stearate and sucrose stearate, by a solvent evaporation method. The effects of the type and concentration of the dispersing agents and the inner phase polymer concentra...

journal_title：Journal of microencapsulation

authors： Horoz BB,Kiliçarslan M,Yüksel N,Baykara T

更新日期：2004-03-01 00:00:00