Preparation, statistical optimisation and in vitro characterisation of poly (3-hydroxybutyrate-co-3-hydroxyvalerate)/poly (lactic-co-glycolic acid) blend nanoparticles for prolonged delivery of teriparatide.

abstract：:Liposomes were introduced first in 1980 for topical drug delivery and since then have attracted considerable interest and generated many speculative claims concerning their potential utility both as a drug carrier and reservoir for controlled release of drugs within various layers of the skin. A number of clinical stu...

journal_title：Journal of microencapsulation

authors： Moghimi SM,Patel HM

更新日期：1993-04-01 00:00:00

abstract：:The microencapsulation of drugs is gaining importance in many research activities. A common technique for preparing microcapsules is the solvent evaporation method which is simple but has a large number of reaction control parameters. This study reports the microcapsulation of allopurinol by the solvent evaporation me...

journal_title：Journal of microencapsulation

authors： Arabi H,Hashemi SA,Fooladi M

更新日期：1996-09-01 00:00:00

abstract：:A combined approach based on drug cyclodextrin (CD) complexation and loading into PLGA nanoparticles (NP) has been developed to improve oxaprozin therapeutic efficiency. This strategy exploits the solubilizing and stabilizing properties of CDs and the prolonged-release and targeting properties of PLGA NPs. Drug-loaded...

journal_title：Journal of microencapsulation

authors： Mura P,Maestrelli F,Cecchi M,Bragagni M,Almeida A

更新日期：2010-01-01 00:00:00

abstract：:Capsules have been prepared based on a polyanion blend of sodium alginate and sodium cellulose sulphate, gelled in the presence of calcium chloride and sodium chloride. In a second step a membrane was formed via the addition of polymethylene-co-guanidine (PMCG), an oligocation. A mechanistic study examined the influen...

journal_title：Journal of microencapsulation

authors： Renken A,Hunkeler D

更新日期：2007-02-01 00:00:00

abstract：:Redox-responsive magnetic protein microcapsules with Fe3O4 magnetic nanoparticles (MNPs) encapsulated inside have been obtained using a facile, cost-effective and fast sonochemical method from hen egg white proteins. Such prepared redox-responsive magnetic hen egg white protein microcapsules (MHEWPMCs) could be easily...

journal_title：Journal of microencapsulation

authors： Zhong S,Cui X,Tian F

更新日期：2015-01-01 00:00:00

abstract：:This study focuses on development and in vitro characterisation of a nasal delivery system based on uncoated or chitosan-coated solid lipid microparticles (SLMs) containing resveratrol, a natural anti-inflammatory molecule, as an effective alternative to the conventional steroidal drugs. The physico-chemical character...

journal_title：Journal of microencapsulation

authors： Martignoni I,Trotta V,Lee WH,Loo CY,Pozzoli M,Young PM,Scalia S,Traini D

更新日期：2016-12-01 00:00:00

abstract：:The objective of this study was to prepare a microparticulate drug delivery system being based on a new thiomer, namely a chitosan 2-iminothiolane conjugate (chitosan-TBA conjugate). Due to thiol groups being immobilized on chitosan, chitosan-TBA conjugate exhibits improved mucoadhesive and permeation enhancing proper...

journal_title：Journal of microencapsulation

authors： Maculotti K,Genta I,Perugini P,Imam M,Bernkop-Schnürch A,Pavanetto F

更新日期：2005-08-01 00:00:00

abstract：:Objective: To improve the water solubility and enhance the oral bioavailability of gambogenic acid (GNA). Methods: GNA-phospholipid complex (GNA-PLC) micelles were successfully prepared by anti-solvent method. Results: The encapsulation efficiency of GNA-PLC micelles can reach 99.33 % (w/w). The average particle size ...

journal_title：Journal of microencapsulation

authors： Wang B,Cheng W,Zhang C,Bao Y,Zha L,Qian J,Hong L,Chen W

更新日期：2019-09-01 00:00:00

abstract：:Radioembolization is used in diagnostic imaging of the lungs and for radioembolization therapy of hepatic tumours. Presently, 99mTc labelled macroaggregates or microspheres of human serum albumin (HAM) are used for this purpose. Poly lactic acid (PLA) is biodegradable, like HAM, and, unlike HAM, is not a blood product...

journal_title：Journal of microencapsulation

authors： Ergün EL,Ercan MT,Selek H,Kaş HS,Ruacan S,Unsal IS,Mutlu M

更新日期：2000-07-01 00:00:00

abstract：:Solid lipid nanoparticles (SLNs) and nanosuspensions (NSs) have shown great promise for improving bioavailability of poorly water-soluble drugs. This study was aimed to develop SLNs and NS of Saquinavir (SQ) for improvement in bioavailability. These formulations were characterized and their pharmacokinetics and biodis...

journal_title：Journal of microencapsulation

authors： Dodiya SS,Chavhan SS,Sawant KK,Korde AG

更新日期：2011-01-01 00:00:00

abstract：:Microcapsules were prepared through an interfacial cross-linking process using terephthaloylchloride and applied to mixtures of a protein (human serum albumin or gelatin) and a polysaccharide. Their properties were compared with those of microcapsules prepared from the protein alone. Morphological characteristics of m...

journal_title：Journal of microencapsulation

authors： Levy MC,Andry MC

更新日期：1991-07-01 00:00:00

abstract：:In this study microspheres of diclofenac sodium, an anti-inflammatory agent, were prepared by utilizing a natural polysaccharide, chitosan-H. The objective of this investigation was to sustain the action of diclofenac sodium and to show the effect of various conditions on release kinetics. For this reason factorial de...

journal_title：Journal of microencapsulation

authors： Açikgöz M,Kaş HS,Orman M,Hincal AA

更新日期：1996-03-01 00:00:00

abstract：:Emulsions of menhaden oil and sodium caseinate (NaCas) incorporating carbohydrates of varying dextrose equivalence (DE) were spray-dried to yield encapsulated fish oil powders. The effects of carbohydrate DE (5.5-38), core/wall ratio and NaCas/carbohydrate ratio on microencapsulation efficiency (ME) and oxidative stab...

journal_title：Journal of microencapsulation

authors： Hogan SA,O'Riordan ED,O'Sullivan M

更新日期：2003-09-01 00:00:00

abstract：:Drug-free polylactic acid (PLA) microspheres were prepared by an emulsification-solvent evaporation technique using different types of protective colloids. The influence of five types of hydrophilic prolymers (polysaccharides, proteins, synthetic cellulose derivatives, synthetic nonionic polymers and surfactants) on t...

journal_title：Journal of microencapsulation

authors： Lin SY,Chen KS,Teng HH

更新日期：1998-05-01 00:00:00

abstract：:To improve poor water solubility of cyclosporine A (CsA), hydroxypropyl-beta-cyclodextrin (HPβCD) was incorporated into the nanoparticle formulation. Solid complexes of CsA with HPβCD in different ratios were prepared by the kneading method. CsA containing alone or in combination with HPβCD in poly-lactide-co-glycolid...

journal_title：Journal of microencapsulation

authors： Aksungur P,Demirbilek M,Denkbaş EB,Unlü N

更新日期：2012-01-01 00:00:00

abstract：:Latex particles coated with either amino or carboxyl groups were labelled with 99mTc. Two labelling methods were used: (1) direct labelling with tin reduction and (2) ligand exchange with tin pyrophosphate. Labelling efficiency and the radiochemical impurities were determined by thin-layer chromatography. Effect of [S...

journal_title：Journal of microencapsulation

authors： Ercan MT,Tuncel SA,Caner BE,Pişkin E

更新日期：1993-01-01 00:00:00

abstract：:In the previous report, microencapsulation of lipase employing a (w/o)/w multiple phase emulsion technique, with 2:1 polystyrene (PS)-SBR mixture being used as a wall material, was proposed. Catalysis of the encapsulated enzyme was investigated, and the hydrolysis of triacetin (triglyceride of acetic acid) was success...

journal_title：Journal of microencapsulation

authors： Iso M,Shirahase T,Hanamura S,Urushiyama S,Omi S

更新日期：1989-07-01 00:00:00

abstract：:Optimum conditions for the preparation of non-magnetic and magnetic microspheres of albumin-globulin mix (alglomix) containing mefenamic acid have been standardized. The effect of various parameters has been investigated with regard to the appearance, yield, drug content and encapsulation efficiency. The physicochemic...

journal_title：Journal of microencapsulation

authors： Lalla JK,Ahuja PL

更新日期：1991-01-01 00:00:00

abstract：:The diblock copolymers based on PBLG and PEO (GE) were synthesized and characterized. Nanoparticles showed spherical shape from the observations of TEM and approved core-shell structure. Drug contents were increased with use of higher initial drug concentration and higher Mw of GE. Nifedipine (NFD) release rate was sl...

journal_title：Journal of microencapsulation

authors： Jeong YI,Sun HS,Shim YH,Kim C,Park SH,Choi KC,Cho CS

更新日期：2004-06-01 00:00:00

abstract：:Eudragit RS microspheres containing verapamil HCl for oral use were prepared using three different dispersing agents: aluminium tristearate, magnesium stearate and sucrose stearate, by a solvent evaporation method. The effects of the type and concentration of the dispersing agents and the inner phase polymer concentra...

journal_title：Journal of microencapsulation

authors： Horoz BB,Kiliçarslan M,Yüksel N,Baykara T

更新日期：2004-03-01 00:00:00

abstract：:Biodegradable polymers for localized delivery of antibiotics have emerged as an important approach to treating orthopaedic infections. In chronic forms of osteomyelitis which are thought to be associated with bacterial biofilm, localized delivery of a suitable antibiotic is desirable. This paper describes the formulat...

journal_title：Journal of microencapsulation

authors： Habib M,Onyilofor S,Ebube NK,Owusu-Ababio G

更新日期：1999-01-01 00:00:00

abstract：:This paper prepared novel biodegradable and pH-sensitive microgels based on Poly(epsilon-caprolactone)-Pluronic-Poly(epsilon-caprolactone)-dimethacrylate (PCFC-DMA), Poly(ethylene glycol) dimethacrylate (PEG-DMA) and methylacrylic acid (MAA) cross-linked with N,N'-methylenebisacrylamide (BIS), initiated by NaHSO(3), K...

journal_title：Journal of microencapsulation

authors： Xu X,Fu S,Wang K,Jia W,Guo G,Zheng X,Dong P,Guo Q,Qian Z

更新日期：2009-11-01 00:00:00

abstract：:This paper describes a novel approach to prepare and characterize calcium-shellac spheres as a carrier of a tooth whitening agent carbamide peroxide. Calcium-shellac spheres were prepared using an extrusion technique based on dropping aqueous ammonium shellac solution into calcium chloride solution. The effects of for...

journal_title：Journal of microencapsulation

authors： Xue J,Zhang Z

更新日期：2008-12-01 00:00:00

abstract：:The objective of this study is to explore the influence of polyvinylpyrrolidone (PVP) quantity on the solubility, crystallinity and oral bioavailability of poorly water-soluble fenofibrate in solvent-evaporated microspheres. Numerous microspheres were prepared with fenofibrate, sodium lauryl sulphate (SLS) and PVP usi...

journal_title：Journal of microencapsulation

authors： Yousaf AM,Kim DW,Kim DS,Kim JO,Youn YS,Cho KH,Yong CS,Choi HG

更新日期：2016-06-01 00:00:00

abstract：:The aim of this study was to formulate, characterise and evaluate the activity of amodiaquine microparticles against Leishmania donovani. Microparticles were formulated by encapsulating the drug in bovine serum albumin using the spray-dryer method. The microparticles were evaluated for size, zeta potential, drug conte...

journal_title：Journal of microencapsulation

authors： Nettey H,Allotey-Babington GL,Somuah I,Banga NB,Afrane B,Amponsah SK,Annor H,Darko H,Hanson K,Aidoo A,Broni MN,Sasu C,Nyarko A

更新日期：2017-02-01 00:00:00

abstract：:The release of fluorescein from polyethylcyanoacrylate (PECA) or polyisobutylcyanoacrylate (PICA) nanoparticles was affected by the surfactants used for the preparation. The different surfactants also modified the molecular weight, size and loading of the nanoparticles. However, these factors were not be responsible f...

journal_title：Journal of microencapsulation

authors： Vandelli MA,Fresta M,Puglisi G,Forni F

更新日期：1994-09-01 00:00:00

abstract：:Sub-100-nm nanoparticles were prepared from beta-lactoglobulin (BLG) with a narrow size distribution by a desolvation method using glutaraldehyde for cross-linking. With pre-heating of the BLG solution to 60 degrees C and subsequent pH readjustment to 9.0, nanoparticles of 59 +/- 5 nm were obtained with improved unifo...

journal_title：Journal of microencapsulation

authors： Ko S,Gunasekaran S

更新日期：2006-12-01 00:00:00

abstract：:The purpose of this study was to design and characterise an oral mucoadhesive micellar drug carrier. In this regard, a mucoadhesive hydrophobic cationic aminocellulose was easily synthesised under mild homogeneous conditions with high yield. The cellulose derivative resulted in strongly improved mucoadhesive propertie...

journal_title：Journal of microencapsulation

authors： Songsurang K,Siraleartmukul K,Muangsin N

更新日期：2015-01-01 00:00:00

abstract：:This work investigated the means for the efficient encapsulation of muramyl dipeptide (MDP) in poly(epsilon-caprolactone) (PCL) microparticles (MP) by a solvent evaporation method in order to optimize the effect of the adjuvant for oral immunization. Therefore, the influence of MDP concentration in the inner aqueous p...

journal_title：Journal of microencapsulation

authors： Youan BB,Benoit MA,Rollmann B,Riveau G,Gillard J

更新日期：1999-09-01 00:00:00

abstract：:Artificial chylomicron remnants were investigated as a new drug carrier system for the targeting of hepatic parenchymal cells. The emulsions presented here are similar in particle size and composition to natural lipoproteins. The preparations contained triolein, phospholipid, cholesterol and cholesteryl oleate. Egg yo...

journal_title：Journal of microencapsulation

authors： Vuaridel-Bonanomi ES,Weder HG

更新日期：1991-04-01 00:00:00