Formulation and evaluation of vinylpyrrolidone/vinylacetate copolymer microspheres with griseofulvin.

abstract：:Documented to exhibit cytotoxicity and poor oral bioavailability, alpha-mangostin was encapsulated into PLGA microspheres with optimization of formulation using response surface methodology. Mixed levels of four factors Face central composite design was employed to evaluate critical formulation variables. With 30 runs...

journal_title：Journal of microencapsulation

authors： Elsaid Ali AA,Taher M,Mohamed F

更新日期：2013-01-01 00:00:00

abstract：:Protamine-oligonucleotide nanoparticles represent effective colloidal drug carriers for antisense phosphorothioate oligonucleotides (PTO). This study describes improvements in particle preparation and the physicochemical properties of the complexes prepared. The influence of component concentrations, length of the PTO...

journal_title：Journal of microencapsulation

authors： Lochmann D,Vogel V,Weyermann J,Dinauer N,von Briesen H,Kreuter J,Schubert D,Zimmer A

更新日期：2004-09-01 00:00:00

abstract：:The effect of process variables such as nozzle size, flow-rate of dispersed phase, inter-electrode distance, and presence of an acid acceptor and a thickening agent in the dispersed phase, on the production and size distribution of nylon 6-10 microcapsules prepared by interfacial polymerization in a high-voltage elect...

journal_title：Journal of microencapsulation

authors： Etuk BR,Weatherley LR,Murray KR

更新日期：1995-03-01 00:00:00

abstract：:The purpose of this study was the preparation, optimisation and in vitro characterisation of PHBV and PLGA blend nanoparticles (NPs) for prolonged delivery of Teriparatide. Double emulsion solvent evaporation technique was employed for the fabrication of NPs. The nanoformulation was optimised using the Box-Behnken met...

journal_title：Journal of microencapsulation

authors： Bahari Javan N,Rezaie Shirmard L,Jafary Omid N,Akbari Javar H,Rafiee Tehrani M,Abedin Dorkoosh F

更新日期：2016-08-01 00:00:00

abstract：:The aim was to study the effect of the type of polymer solvent on characteristics of microspheres produced by spray drying. The water-soluble model protein, bovine serum albumin (BSA) was microencapsulated into biodegradable poly(D,L-lactic acid) using the following 10 different polymer solvents: acetaldehyde dimethyl...

journal_title：Journal of microencapsulation

authors： Gander B,Wehrli E,Alder R,Merkle HP

更新日期：1995-01-01 00:00:00

abstract：:Microspheres, including microcapsules and cells or beads, are widely used to produce many functional products. Information about their mechanical properties is essential to understanding their performance during manufacturing, processing and end-use applications. The mechanical characterization of microspheres require...

journal_title：Journal of microencapsulation

authors： Mercadé-Prieto R,Zhang Z

更新日期：2012-01-01 00:00:00

abstract：:D,L-polylactic acid (PLA) microspheres containing quinidine base and quinidine sulphate were prepared by the solvent evaporation method. The present study was carried out to examine how various process parameters in the aqueous phase influenced the preparation and properties of PLA-microspheres. The amount of drug tha...

journal_title：Journal of microencapsulation

authors： Bodmeier R,McGinity JW

更新日期：1987-10-01 00:00:00

abstract：AIMS:This study was conducted to evaluate block copolymers containing two different poly(ethyleneimine) (PEI) amounts, as new pH-sensitive micellar delivery systems for doxorubicin. METHODS:Micelles were prepared with block copolymers consisting of poly(2-ethyl-2-oxazoline)-co-poly(ethyleneimine) (PEtOx-co-PEI) and po...

journal_title：Journal of microencapsulation

authors： Ozturk N,Kara A,Gulyuz S,Ozkose UU,Tasdelen MA,Bozkir A,Yilmaz O,Vural I

更新日期：2020-11-01 00:00:00

abstract：:Acidic and basic nonsteroidal anti-inflammatory drugs were encapsulated with cellulose derivatives having different functional groups, acidic (carboxymethyl cellulose), basic (chitosan), and neutral (hydroxypropylmethyl cellulose). The properties of the microcapsules were studied and the interaction of the drugs with ...

journal_title：Journal of microencapsulation

authors： Meshali MM,el-Dien EZ,Omar SA,Luzzi LA

更新日期：1989-07-01 00:00:00

abstract：:Graft copolymer polyethylenimine-graft-poly(N-vinylpyrrolidone) (PEI-g-PVP) was prepared by coupling mono carboxyl-terminated PVP (PVP-COOH) with PEI using N,N'-dicyclohexylcarbodiimide (DCC) and N-hydroxysuccinimide (NHS) as coupling agents. In aqueous medium, PVP-g-PEI can self-assemble into stable polyion complex m...

journal_title：Journal of microencapsulation

authors： Yuan J,Luo Y,Gao Q

更新日期：2011-01-01 00:00:00

abstract：:The effect of lecithin and starch on viability of alginate encapsulated probiotics was determined at different temperatures. Probiotic organisms (1% v/v>10Log CFU ml(-1)) were encapsulated using alginate (2% w/v), gelatinized starches (2% w/v) and lecithin (0-4% w/v) and stored in sealed containers at 4, 23 and 37 deg...

journal_title：Journal of microencapsulation

authors： Donthidi AR,Tester RF,Aidoo KE

更新日期：2010-01-01 00:00:00

abstract：:A novel method for preparing the PLGA nanospheres with hydrophilic surface has been designed and characterized. Because of good solubility of tetraglycol in water, PLGA (poly(lactide-co-glycolide)) nanospheres were formed by spraying the PLGA/tetraglycol solution into water. The size of PLGA nanospheres was manipulate...

journal_title：Journal of microencapsulation

authors： Kim BK,Kim D,Cho SH,Yuk SH

更新日期：2004-11-01 00:00:00

abstract：:Capsules have been prepared based on a polyanion blend of sodium alginate and sodium cellulose sulphate, gelled in the presence of calcium chloride and sodium chloride. In a second step a membrane was formed via the addition of polymethylene-co-guanidine (PMCG), an oligocation. A mechanistic study examined the influen...

journal_title：Journal of microencapsulation

authors： Renken A,Hunkeler D

更新日期：2007-02-01 00:00:00

abstract：:Polyurethane modified with polylactic acid microcapsules were fabricated for controlled release of chlorpyrifos (one of the high usage solid phosphorous insecticides) via interfacial polymerisation with diphenylmethane diisocyanate, polyether triol, 1,4-butanediol and polylactic acid as modifier. The structure, morpho...

journal_title：Journal of microencapsulation

authors： Zheng T,Chen K,Chen W,Wu B,Sheng Y,Xiao Y

更新日期：2019-01-01 00:00:00

abstract：:The present study describes the development of a new cyclosporine formulation based on polycaprolactone (PCL) microspheres (MS) prepared by the solvent evaporation method. Ternary phase diagrams were used to identify the domains where MS were formed. The application of central composite designs established the influen...

journal_title：Journal of microencapsulation

authors： Aberturas MR,Molpeceres J,Guzmán M,García F

更新日期：2002-01-01 00:00:00

abstract：:Encapsulation of mefenamic acid (MFA), a potent non-steroidal anti-inflammatory drug with cationic acrylic resin, Eudragit E, was carried out using a fluidized-bed granulator (Glatt AG). Three drug:polymer ratios were prepared using 50 ml of 1, 2.5 and 5 per cent w/v aqueous suspension of Eudragit to coat 100 mg powde...

journal_title：Journal of microencapsulation

authors： Ramadan EM,el-Helw A,el-Said Y

更新日期：1987-04-01 00:00:00

abstract：:The use of polymeric carriers in formulations of therapeutic drug delivery systems has gained widespread application, due to their advantage of being biodegradable and biocompatible. Among the microparticulate systems, microspheres have a special importance since it is possible to target drugs and provide controlled r...

journal_title：Journal of microencapsulation

authors： Tunçay M,Caliş S,Kaş HS,Ercan MT,Peksoy I,Hincal AA

更新日期：2000-03-01 00:00:00

abstract：:Clinical applications of Sesbania grandiflora bark extract (SGE) are limited because of its poor water solubility and stability. SGE was loaded in micelles of Pluronics. In vitro and in vivo antibacterial and toxicity tests were investigated using broth dilution and silkworm model. Aqueous solubility of SGE was improv...

journal_title：Journal of microencapsulation

authors： Anantaworasakul P,Okonogi S

更新日期：2017-02-01 00:00:00

abstract：:Bioavailability of oral drugs can be limited by an intestinal excretion process mediated by P-glycoprotein (P-gp). Polyethylene glycol (PEG) is a known P-gp inhibitor. Dispersion of Famotidine (a P-gp substrate) within PEGylated nanoparticles (NPs) was used to improve its oral bioavailability. In this work, we evaluat...

journal_title：Journal of microencapsulation

authors： Mokhtar M,Gosselin P,Lacasse F,Hildgen P

更新日期：2017-02-01 00:00:00

abstract：:An extrusion-based encapsulation process has been developed for making salt grain-sized iron premix for salt fortification. The first step of extrusion agglomeration process has been studied and reported previously. The focus of this study is on the optimisation of the colour-masking and polymer coating steps. Several...

journal_title：Journal of microencapsulation

authors： Yadava D,Olive Li Y,Diosady LL,Wesley AS

更新日期：2012-01-01 00:00:00

abstract：:The development of microparticulate food particles for marine suspension-feeders is discussed with respect to the difficulties of nutrient delivery in the aquatic environment and to feeding and digestion in crustacea and bivalve molluscs. Loss of nutrients from particles suspended in seawater must be minimized by eith...

journal_title：Journal of microencapsulation

authors： Langdon CJ,Levine DM,Jones DA

更新日期：1985-01-01 00:00:00

abstract：:Alginate bead containing calcium carbonate particle were prepared by dropping the suspension of alginate/calcium carbonate (4/1, w/w) into aqueous solution of CaCl(2) (0.1 M). The pH-dependent release property of the bead was observed for 12 h using blue dextran as a model drug. The release increased up to 4 h in a sa...

journal_title：Journal of microencapsulation

authors： Han MR,Kwon MC,Lee HY,Kim JC,Kim JD,Yoo SK,Sin IS,Kim SM

更新日期：2007-12-01 00:00:00

abstract：CONTEXT:Quercetin (QUE) is a flavonoid with antioxidant/anti-inflammatory properties, poorly absorbed when orally administered. OBJECTIVES:To prepare chitosan/xanthan gum microparticles to increase QUE oral bioavailability and optimize its release in the colon. MATERIALS AND METHODS:Chitosan/xanthan gum hydrogel embe...

journal_title：Journal of microencapsulation

authors： Caddeo C,Nácher A,Díez-Sales O,Merino-Sanjuán M,Fadda AM,Manconi M

更新日期：2014-01-01 00:00:00

abstract：PURPOSE:To develop a stable and reproducible modified release pellet formulation containing ibuprofen. METHODS:Using extrusion-spheronization technology to produce pellets. RESULTS:The percentage yield, size distribution and overall pellet shape within the desired size range of 1000-1400 microm was found to be depend...

journal_title：Journal of microencapsulation

authors： Lutchman D,Dangor CM,Perumal D

更新日期：2005-09-01 00:00:00

abstract：:The formation of microcapsules which contain rosemary oil, is herewith described. The process is based on two steps: (a) formation of oil-in-water emulsions, by using lecithin as emulsifier, thus imparting negative charges on the oil droplets; (b) addition of a cationic biopolymer, chitosan, in conditions that favor t...

journal_title：Journal of microencapsulation

authors： Magdassi S,Bach U,Mumcuoglu KY

更新日期：1997-03-01 00:00:00

abstract：:Solid lipid nanoparticles (SLNs) and nanosuspensions (NSs) have shown great promise for improving bioavailability of poorly water-soluble drugs. This study was aimed to develop SLNs and NS of Saquinavir (SQ) for improvement in bioavailability. These formulations were characterized and their pharmacokinetics and biodis...

journal_title：Journal of microencapsulation

authors： Dodiya SS,Chavhan SS,Sawant KK,Korde AG

更新日期：2011-01-01 00:00:00

abstract：:Microencapsulation aims to protect polyunsaturated fatty acids against oxidation by embedding oil droplets in a solid matrix. The effect of the oil droplet size on the oxidation was evaluated under consideration of the non-encapsulated oil and the powder particle size. An O/W emulsion (1.6%(w/w) soy protein; 30.4%(w/w...

journal_title：Journal of microencapsulation

authors： Linke A,Hinrichs J,Kohlus R

更新日期：2020-03-01 00:00:00

abstract：:Co-flowing media of a polymeric solution (30 wt% polymethylsilsesquioxane in ethanol) and a ceramic suspension (10 wt% alumina in glycerol) were subjected to an electric field. The flow rates of the media (10-30 microL min(-1)) and the applied voltage (0-11 kV) were varied systematically during the experimentation by ...

journal_title：Journal of microencapsulation

authors： Nangrejo M,Ahmad Z,Edirisinghe M

更新日期：2010-01-01 00:00:00

abstract：:To overcome the recurrence problem in bladder tumours; nanoparticles with positive surface charge may improve interaction with biological membranes for intravesical administration. The aim of this study was to design, develop and evaluate (in vitro-in vivo) cationic nanoparticles based on chitosan, poly-L-lysine or po...

journal_title：Journal of microencapsulation

authors： Erdoğar N,Iskit AB,Mungan NA,Bilensoy E

更新日期：2012-01-01 00:00:00

abstract：:Bacampicillin hydrochloride has been microencapsulated to mask its very bitter taste. The objective of the study was to compare the in vitro release and bioavailability of bacampicillin hydrochloride from microcapsules coated with two principally different polymers: a water-insoluble polymer, ethylcellulose, and an ac...

journal_title：Journal of microencapsulation

authors： Sjöqvist R,Nyqvist H,Sjövall J,Westerlund D

更新日期：1985-04-01 00:00:00