Abstract：
:Nanoencapsulation by spray drying was performed to protect and preserve antioxidant rich dietary polyphenols from green coffee beans. Nano-encapsulation of green coffee was done using maltodextrin as wall material. The nanoparticles were further characterised by zetasizer, differential scanning colorimetry, X-ray diffraction, In vitro gastric intestinal studies and storage stability. Optimal nanoparticles were obtained at a drying temperature of 125 °C and 2:1 Mwall/Mcore ratio (10% w/w maltodextrin), provided better encapsulation yield (40% w/w) and 70 ± 5% (w/w) encapsulation efficiency with 82.34 nm particle size, -28.8 mV zeta-potential. The In-vitro bioactivity of nanoparticles ensured 80 ± 2% (w/w) of chlorogenic acid availability in a controlled release in the intestine. Storage stability of nanoparticles under varied temperature was remarkably improved compared to non-encapsulated green coffee extract. However, the results indicated that the potential benefits of using maltodextrin coated green coffee nanoparticles for controlled release of Chlorogenic acid and sufficient antioxidative protection during prolonged period.
journal_name
J Microencapsuljournal_title
Journal of microencapsulationauthors
Desai NM,Gilbert Stanley J,Murthy PSdoi
10.1080/02652048.2019.1692946subject
Has Abstractpub_date
2020-01-01 00:00:00pages
52-64issue
1eissn
0265-2048issn
1464-5246journal_volume
37pub_type
杂志文章abstract：:Co-flowing media of a polymeric solution (30 wt% polymethylsilsesquioxane in ethanol) and a ceramic suspension (10 wt% alumina in glycerol) were subjected to an electric field. The flow rates of the media (10-30 microL min(-1)) and the applied voltage (0-11 kV) were varied systematically during the experimentation by ...
journal_title：Journal of microencapsulation
pub_type： 杂志文章
doi：10.3109/02652048.2010.489973
更新日期：2010-01-01 00:00:00
abstract：:H-n.m.r. spectroscopy of small unilamellar phospholipid vesicles in the presence of the lanthanide probe ion Dy3+ has been used to study the permeability of these liposomes induced by the bile salts (glycocholate and glycodeoxycholate) and pancreatic phospholipase A2. A marked synergism is demonstrated in the combined...
journal_title：Journal of microencapsulation
pub_type： 杂志文章
doi：10.3109/02652048409038515
更新日期：1984-04-01 00:00:00
abstract：:The objective of this study was to prepare floating theophylline microspheres with zero order release profiles for use as buoyant reservoirs with increased retention time in the stomach. The microspheres were prepared by a modified emulsion-solvent evaporation method using a polymer mixture of cellulose acetate butyra...
journal_title：Journal of microencapsulation
pub_type： 杂志文章
doi：10.3109/02652049809008255
更新日期：1998-11-01 00:00:00
abstract：:The development of microparticulate food particles for marine suspension-feeders is discussed with respect to the difficulties of nutrient delivery in the aquatic environment and to feeding and digestion in crustacea and bivalve molluscs. Loss of nutrients from particles suspended in seawater must be minimized by eith...
journal_title：Journal of microencapsulation
pub_type： 杂志文章,评审
doi：10.3109/02652048509049572
更新日期：1985-01-01 00:00:00
abstract：:Eudragit RS microspheres containing verapamil HCl for oral use were prepared using three different dispersing agents: aluminium tristearate, magnesium stearate and sucrose stearate, by a solvent evaporation method. The effects of the type and concentration of the dispersing agents and the inner phase polymer concentra...
journal_title：Journal of microencapsulation
pub_type： 杂志文章
doi：10.1080/02652040310001637893
更新日期：2004-03-01 00:00:00
abstract：:Cross-linked albumin microcapsules were prepared, using a polycondensation interfacial process. Doxorubicin was incorporated in these microcapsules by simple adsorption from aqueous solution. Increasing the extent of cross-linkage of the microcapsule walls by either increasing the cross-linking agent concentration or ...
journal_title：Journal of microencapsulation
pub_type： 杂志文章
doi：10.3109/02652048809064170
更新日期：1988-07-01 00:00:00
abstract：:A biocompatible emulsification method has been developed for microencapsulation of live cells and enzymes within a calcium alginate matrix. Fabrication of alginate beads was achieved by premixing a sequestering agent (sodium polyphosphate) and the calcium source (calcium sulphate) with the hydrogel monomer prior to th...
journal_title：Journal of microencapsulation
pub_type： 杂志文章
doi：10.3109/02652049509010294
更新日期：1995-05-01 00:00:00
abstract：:Regular spherical microspheres of 220-260 microns average size have been prepared from vinylpyrrolidone/vinylacetate copolymer using a solvent evaporation method. Griseofulvin has been incorporated into these microspheres and its physical characterization has been carried out by differential scanning calorimetry (DSC)...
journal_title：Journal of microencapsulation
pub_type： 杂志文章
doi：10.3109/02652049309015315
更新日期：1993-01-01 00:00:00
abstract：:The physical entrapment of a hydrophilic drug within degradable microspheres is generally difficult because of poor entrapment yield and/or fast release, depending on the microsphere fabrication method. In order to counter the effects of drug hydrophilicity, it is proposed to covalently attach the drug to lactic acid ...
journal_title：Journal of microencapsulation
pub_type： 杂志文章
doi：10.1080/026520400417667
更新日期：2000-09-01 00:00:00
abstract：:Graft copolymer polyethylenimine-graft-poly(N-vinylpyrrolidone) (PEI-g-PVP) was prepared by coupling mono carboxyl-terminated PVP (PVP-COOH) with PEI using N,N'-dicyclohexylcarbodiimide (DCC) and N-hydroxysuccinimide (NHS) as coupling agents. In aqueous medium, PVP-g-PEI can self-assemble into stable polyion complex m...
journal_title：Journal of microencapsulation
pub_type： 杂志文章
doi：10.3109/02652048.2010.534823
更新日期：2011-01-01 00:00:00
abstract：:Oil-containing polyterephthalamide microcapsules were synthesized by the interfacial polymerization of an oil-soluble monomer (terephthaloyl dichloride, TDC) and a mixture of two water-soluble monomers (diethylenetriamine, DETA, and 1, 6-hexamethylenediamine, HMDA). The influence of several synthesis parameters (e.g. ...
journal_title：Journal of microencapsulation
pub_type： 杂志文章
doi：10.1080/02652040110055243
更新日期：2001-11-01 00:00:00
abstract：:The use of polymeric carriers in formulations of therapeutic drug delivery systems has gained widespread application, due to their advantage of being biodegradable and biocompatible. Among the microparticulate systems, microspheres have a special importance since it is possible to target drugs and provide controlled r...
journal_title：Journal of microencapsulation
pub_type： 杂志文章
doi：10.1080/026520400288382
更新日期：2000-03-01 00:00:00
abstract：:Atomic force microscopy (AFM) is recognized a suitable and powerful technique for surface and morphological analysis. Even if until now this technique has not been frequently used in the pharmaceutical field, it can contribute to an accurate morphologic characterization of microspheres and nanospheres. In this work, a...
journal_title：Journal of microencapsulation
pub_type： 杂志文章
doi：10.1080/02652040500435220
更新日期：2006-03-01 00:00:00
abstract：:Abietic acid was isolated from rosin N Grade (ISI) by a simple process and the product was further standardized. Sulphadiazine microcapsules were prepared by the solvent evaporation technique, using abietic acid as a wall-forming material. Discrete, spherical and free-flowing microcapsules were obtained by phase separ...
journal_title：Journal of microencapsulation
pub_type： 杂志文章
doi：10.3109/02652049209040481
更新日期：1992-10-01 00:00:00
abstract：:Transplantation of cells genetically modified to produce neurotrophins is a promising spinal cord repair strategy. Previously we showed that fibroblasts engineered to produce brain-derived neurotrophic factor (Fb/BDNF) microencapsulated in alginate survive, continue to grow and express bioactive BDNF. We here compared...
journal_title：Journal of microencapsulation
pub_type： 杂志文章
doi：10.3109/02652048.2011.569765
更新日期：2011-01-01 00:00:00
abstract：:This study demonstrates the feasibility of using a single-capillary electrospray (ES) system to generate novel alpha-lipoic acid encapsulated poly(ethylene oxide)-chitosan (ALA/PEO/CS) particles with a monodispersed diameter. Scanning electron microscopic images (SEM) and dynamic light scattering (DLS) results indicat...
journal_title：Journal of microencapsulation
pub_type： 杂志文章
doi：10.3109/02652048.2013.863395
更新日期：2014-01-01 00:00:00
abstract：:Ionotropic gelation was used to entrap sulindac into calcium alginate beads as a potential drug carrier for the oral delivery of this anti-inflammatory drug. Beads were investigated in vitro for a possible sustained drug release and their use in vivo as a gastroprotective system for sulindac. Process parameters such a...
journal_title：Journal of microencapsulation
pub_type： 杂志文章
doi：10.1080/02652040701298153
更新日期：2007-06-01 00:00:00
abstract：:Magnetic and pH-responsive chitosan microcapsules (MPRCMCs) were prepared by a simple sonochemical method. Superparamagnetic oleic acid modified Fe3O4 nanoparticles (OA-Fe3O4 NPs) and hydrophobic drugs could be directly loaded into MPRCMCs during sonication. The obtained microcapsules had a well-defined spherical morp...
journal_title：Journal of microencapsulation
pub_type： 杂志文章
doi：10.3109/02652048.2016.1144817
更新日期：2016-01-01 00:00:00
abstract：:Sub-100-nm nanoparticles were prepared from beta-lactoglobulin (BLG) with a narrow size distribution by a desolvation method using glutaraldehyde for cross-linking. With pre-heating of the BLG solution to 60 degrees C and subsequent pH readjustment to 9.0, nanoparticles of 59 +/- 5 nm were obtained with improved unifo...
journal_title：Journal of microencapsulation
pub_type： 杂志文章
doi：10.1080/02652040601035143
更新日期：2006-12-01 00:00:00
abstract：:Redox-responsive magnetic protein microcapsules with Fe3O4 magnetic nanoparticles (MNPs) encapsulated inside have been obtained using a facile, cost-effective and fast sonochemical method from hen egg white proteins. Such prepared redox-responsive magnetic hen egg white protein microcapsules (MHEWPMCs) could be easily...
journal_title：Journal of microencapsulation
pub_type： 杂志文章
doi：10.3109/02652048.2015.1073389
更新日期：2015-01-01 00:00:00
abstract：:The aim of this study was to design and develop microspheres of indomethacin with pH and transit time dependent release properties for achieving targeted delivery to the colon. Microspheres containing varying proportions of ethyl cellulose and Eudragit (L100 or S100) either alone or in combination were prepared using ...
journal_title：Journal of microencapsulation
pub_type： 杂志文章
doi：10.1080/02652040802424021
更新日期：2009-08-01 00:00:00
abstract：:Acidic and basic nonsteroidal anti-inflammatory drugs were encapsulated with cellulose derivatives having different functional groups, acidic (carboxymethyl cellulose), basic (chitosan), and neutral (hydroxypropylmethyl cellulose). The properties of the microcapsules were studied and the interaction of the drugs with ...
journal_title：Journal of microencapsulation
pub_type： 杂志文章
doi：10.3109/02652048909019916
更新日期：1989-07-01 00:00:00
abstract：:Encapsulated vitro-derived apical buds of M.26 apple rootstock (Malus pumila Mill) can be employed for the formation of the synthetic seed. Satisfactory levels of conversion (plantlets from synthetic seed) can be achieved if there are adequate (i) rooting induction treatment, (ii) protocol of encapsulation, and (iii) ...
journal_title：Journal of microencapsulation
pub_type： 杂志文章
doi：10.1080/02652040110105337
更新日期：2002-05-01 00:00:00
abstract：:Drug release from gelatin/poly(acrylic acid) oxprenolol-loaded microspheres has been evaluated using an in situ sink immersion method and a wetting method. The kinetics of drug release were analysed by applying the empirical exponential equation and by the calculation of the approximate contribution of the diffusional...
journal_title：Journal of microencapsulation
pub_type： 杂志文章
doi：10.3109/02652049709033835
更新日期：1997-07-01 00:00:00
abstract：:Silica gel microspheres are ideal materials for bioencapsulation due to their mechanical properties, biocompatibility, and stability. Encapsulated cells are isolated from the environment and protected from predators, changes in pH, and osmotic stress. However methods for the production of silica gel microspheres suita...
journal_title：Journal of microencapsulation
pub_type： 杂志文章
doi：10.1080/02652048.2016.1202346
更新日期：2016-08-01 00:00:00
abstract：:Moisture curing type self-healing microcapsules become more attractive, while instability of active core material crippled the efficiency of self-healing behaviour. Polyurea (PU)/melamine formaldehyde (MF) double-layered self-healing microcapsules containing isophorone diisocyanate (IPDI) core with high and stable cor...
journal_title：Journal of microencapsulation
pub_type： 杂志文章
doi：10.1080/02652048.2016.1178352
更新日期：2016-06-01 00:00:00
abstract：:The purpose of this study was to design and characterise an oral mucoadhesive micellar drug carrier. In this regard, a mucoadhesive hydrophobic cationic aminocellulose was easily synthesised under mild homogeneous conditions with high yield. The cellulose derivative resulted in strongly improved mucoadhesive propertie...
journal_title：Journal of microencapsulation
pub_type： 杂志文章
doi：10.3109/02652048.2015.1046516
更新日期：2015-01-01 00:00:00
abstract：:The effect of several parameters on the size of alginate beads produced by use of an electrostatic potential bead generator was examined. Parameters studied included needle diameter, electrostatic potential, alginate solution flow rate, gelling ion concentration and alginate concentration and viscosity, as well as alg...
journal_title：Journal of microencapsulation
pub_type： 杂志文章
doi：10.1080/02652040210144234
更新日期：2002-07-01 00:00:00
abstract：:For the preparation of microcapsules using the W/O/W (water in oil in water) emulsion system, it is essential to control various factors such as the dispersed state of the organic phase in the W/O/W emulsion, the difference in the solute concentration between the inner and outer aqueous phases and the volume fraction ...
journal_title：Journal of microencapsulation
pub_type： 杂志文章
doi：10.1080/0265204031000093096
更新日期：2003-07-01 00:00:00
abstract：:Provision and maintenance of adequate concentrations of antibiotics at infection sites is very important in treating highly resistant infections. For diseases like implant related osteomyelitis (IRO) it is best to provide this locally via implanted drug formulations, as systemic administration of the antibiotic may no...
journal_title：Journal of microencapsulation
pub_type： 杂志文章
doi：10.1080/02652040110065413
更新日期：2002-03-01 00:00:00
