Abstract:
:Monodisperse albumin microspheres were successfully prepared by both chemical or thermal hardening methods via membrane emulsification using microporous glass membranes with uniform pore sizes. The monodispersity of the microspheres was found to depend strongly on parameters such as albumin concentration, emulsifier concentration, and volume ratio of the internal aqueous phase (albumin solution) to the dispersion medium (organic solvent). The optimum conditions for obtaining monodisperse albumin microspheres are described.
journal_name
J Microencapsuljournal_title
Journal of microencapsulationauthors
el-Mahdy M,Ibrahim ES,Safwat S,el-Sayed A,Ohshima H,Makino K,Muramatsu N,Kondo Tdoi
10.3109/02652049809008248subject
Has Abstractpub_date
1998-09-01 00:00:00pages
661-73issue
5eissn
0265-2048issn
1464-5246journal_volume
15pub_type
杂志文章abstract::The effect of lecithin and starch on viability of alginate encapsulated probiotics was determined at different temperatures. Probiotic organisms (1% v/v>10Log CFU ml(-1)) were encapsulated using alginate (2% w/v), gelatinized starches (2% w/v) and lecithin (0-4% w/v) and stored in sealed containers at 4, 23 and 37 deg...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.3109/02652040902982183
更新日期:2010-01-01 00:00:00
abstract::Biodegradable hollow capsules filled with fluorescently labelled bovine serum albumin (BSA) as a model drug were prepared via layer-by-layer (LbL) self-assembly of type-I collagen (COL) and hyaluronic acid (HA) using calcium carbonate micro-particles and co-precipitation method. Capsules loaded with fluorescein isothi...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.3109/02652048.2013.834995
更新日期:2014-01-01 00:00:00
abstract:CONTEXT:Solid lipid nanoparticles (SLNs) can efficiently and efficaciously incorporate anti-cancer agents. OBJECTIVE:To prepare and characterise tamoxifen (TAM)-loaded SLNs. MATERIALS AND METHODS:Glyceryl monostearate, Tween-80, and trehalose were used in SLNs. SLNs were tested via dynamic light scattering (DLS), tra...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.3109/02652048.2014.898707
更新日期:2014-01-01 00:00:00
abstract::Palmatine (PM) is a potent anti-infective agent used to treat eye diseases. However, PM is less effective for ocular application due to short residence time within the eyes. This study aimed to develop a cationic lipid emulsions (CLEs) for ophthalmic delivery of PM and evaluate its suitability in infection treatment. ...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.1080/02652048.2016.1248512
更新日期:2016-12-01 00:00:00
abstract::The use of polymeric carriers in formulations of therapeutic drug delivery systems has gained widespread application, due to their advantage of being biodegradable and biocompatible. Among the microparticulate systems, microspheres have a special importance since it is possible to target drugs and provide controlled r...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.1080/026520400288382
更新日期:2000-03-01 00:00:00
abstract::Clinical applications of Sesbania grandiflora bark extract (SGE) are limited because of its poor water solubility and stability. SGE was loaded in micelles of Pluronics. In vitro and in vivo antibacterial and toxicity tests were investigated using broth dilution and silkworm model. Aqueous solubility of SGE was improv...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.1080/02652048.2017.1284277
更新日期:2017-02-01 00:00:00
abstract::This article describes the development of a freeze-dried formulation of chitosan (CS) nanocapsules containing docetaxel (DCX) and the evaluation of its efficacy in the NCI-H460 cancer cell line. More specifically, two prototypes of nanocapsules differing in their coating, CS alone or in combination with poloxamer 188 ...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.3109/02652048.2012.714411
更新日期:2013-01-01 00:00:00
abstract::In this study, we evaluated a system for oral vaccine delivery, consisting of liposomes coated first with a layer of tremella and then with an outer layer of acid-induced alginate. In vitro release studies showed that the triple layer of alginate-tremella-liposomes was more resistant to an acidic pH and modulated the ...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.3109/02652048.2010.523796
更新日期:2011-01-01 00:00:00
abstract::Polylactic acid microcapsules containing randomly distributed hydrocortisone particles were prepared. The rate of release of hydrocortisone from the microcapsules in pH 7.4 phosphate buffer was found to be largely increased by the presence of polysorbate 80, cetylpyridinium chloride, or aerosol OT in the dissolution m...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.3109/02652048809036721
更新日期:1988-01-01 00:00:00
abstract::Freeze-drying is an effective way to improve long-term physical stability of nanosuspension in drug delivery applications. Nanosuspension also known as suspension of nanoparticles. In this study, the effect of freeze-drying with different cryoprotectants on the physicochemical characteristics of resveratrol (RSV) nano...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.1080/02652048.2018.1462416
更新日期:2018-05-01 00:00:00
abstract::Microspheres, including microcapsules and cells or beads, are widely used to produce many functional products. Information about their mechanical properties is essential to understanding their performance during manufacturing, processing and end-use applications. The mechanical characterization of microspheres require...
journal_title:Journal of microencapsulation
pub_type: 杂志文章,评审
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更新日期:2012-01-01 00:00:00
abstract::Low molecular weight heparin (LMWH)-loaded flexible liposomes (flexosomes) were formulated for transdermal delivery, and their physicochemical and pharmacokinetic parameters were compared with LMWH-loaded ethosomes. Flexosomes had similar particle size compared with ethosomes, but their deformability was higher than t...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.3109/02652048.2010.507880
更新日期:2011-01-01 00:00:00
abstract::The mechanism by which microcapsule aggregation is diminished in the presence of low concentrations of adjunct non-walling polymers such as polyisobutylene (PIB) in organic solvents is uncertain. It is here investigated by phase separation studies employing the non-solvent addition method (cyclohexane) in parallel wit...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.3109/02652049009028419
更新日期:1990-01-01 00:00:00
abstract:AIM:To develop a biocompatible cobalt ferrite (CF-NP) nanodrug formulation using oleic acid and poly (d,l-lactide-co-glycolic) acid (PLGA) for the delivery of docetaxel (DTX) specifically to breast cancer cells. METHODS:The CF-NP were synthesised by hydrothermal method and conjugated with DTX in a PLGA matrix and were...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.1080/02652048.2020.1842529
更新日期:2021-01-01 00:00:00
abstract::This study demonstrates the feasibility of using a single-capillary electrospray (ES) system to generate novel alpha-lipoic acid encapsulated poly(ethylene oxide)-chitosan (ALA/PEO/CS) particles with a monodispersed diameter. Scanning electron microscopic images (SEM) and dynamic light scattering (DLS) results indicat...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.3109/02652048.2013.863395
更新日期:2014-01-01 00:00:00
abstract::The bioavailability of marketed nitrofurantoin capsules was compared to capsules filled with Gantrez-gelatin nitrofurantoin microcapsules of a core:coat ratio of 1:2. The collective results obtained from the analysis of urine samples of five volunteers indicated that nitrofurantoin microcapsules provided a prolonged r...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.3109/02652048809036727
更新日期:1988-10-01 00:00:00
abstract::Ibuprofen-loaded polystyrene microparticles were prepared by the emulsion-solvent evaporation process from an aqueous system. The effects of different parameters on the drug content and on the release of the drug from the microparticles were investigated. The drug content, in all the formulations, was less than the th...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.1080/026520400288553
更新日期:2000-01-01 00:00:00
abstract::Since 1978 we have prepared microencapsulated insecticides by complex coacervation and interfacial polymerization for household insect pest control, fenthion being the main core element. A series of tests have been conducted against mosquitoes (Culex pipiens quinquefasciatus), cockroaches (Periplaneta americana) and b...
journal_title:Journal of microencapsulation
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doi:10.3109/02652048409031543
更新日期:1984-10-01 00:00:00
abstract::Biodegradable polymers for localized delivery of antibiotics have emerged as an important approach to treating orthopaedic infections. In chronic forms of osteomyelitis which are thought to be associated with bacterial biofilm, localized delivery of a suitable antibiotic is desirable. This paper describes the formulat...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.1080/026520499289284
更新日期:1999-01-01 00:00:00
abstract:PURPOSE:Naproxen CR tablets have been obtained from its microspheres prepared by coprecipitation with Eudragit L100-55. The purpose of this work was to evaluate the main and interaction effects of deaggregating agent concentration (X1), compression pressure (X2) and amount of precipitating water (X3) on naproxen releas...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.1080/02652040110055630
更新日期:2001-09-01 00:00:00
abstract::A biocompatible emulsification method has been developed for microencapsulation of live cells and enzymes within a calcium alginate matrix. Fabrication of alginate beads was achieved by premixing a sequestering agent (sodium polyphosphate) and the calcium source (calcium sulphate) with the hydrogel monomer prior to th...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.3109/02652049509010294
更新日期:1995-05-01 00:00:00
abstract::The real issue in the development of oral controlled release dosage forms is not just to prolong the delivery of drugs but also to prolong the presence of dosage forms in the stomach in order to improve the bioavailability of drugs with a 'narrow absorption window'. In the present study, an anti-ulcer drug, ranitidine...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.1080/02652040801973101
更新日期:2008-08-01 00:00:00
abstract::This work aimed to investigate the potential effect of cyclodextrin encapsulation on intrinsic ability of daidzein (DAD) and genistein (GEN) to inhibit the glycosaminoglycan (GAG) synthesis in fibroblasts originating from patients with mucopolysaccharidosis (MPS), type II and III. DAD or GEN encapsulation with either ...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.1080/02652048.2017.1409819
更新日期:2018-01-01 00:00:00
abstract::Isoniazid was encapsulated into microspheres of alginate-chitosan by means of a complex coacervation method in an emulsion system. Since the encapsulation of isoniazid tends to be limited by its hydrophilic characteristics, this study proposes its microencapsulation by adsorption. The particles were prepared in three ...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:
更新日期:2003-03-01 00:00:00
abstract::Co-flowing media of a polymeric solution (30 wt% polymethylsilsesquioxane in ethanol) and a ceramic suspension (10 wt% alumina in glycerol) were subjected to an electric field. The flow rates of the media (10-30 microL min(-1)) and the applied voltage (0-11 kV) were varied systematically during the experimentation by ...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.3109/02652048.2010.489973
更新日期:2010-01-01 00:00:00
abstract::For the preparation of microcapsules using the W/O/W (water in oil in water) emulsion system, it is essential to control various factors such as the dispersed state of the organic phase in the W/O/W emulsion, the difference in the solute concentration between the inner and outer aqueous phases and the volume fraction ...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.1080/0265204031000093096
更新日期:2003-07-01 00:00:00
abstract::Nanoparticles prepared of human serum albumin (HSA) represent promising carriers for drug delivery. Desolvating procedure is a common method to obtain protein-based particles. However process parameters have a great influence on size, size distribution and particle yield of the resulting formulation. Therefore, it is ...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.3109/02652048.2011.635218
更新日期:2012-01-01 00:00:00
abstract:AIM:This study aimed to evaluate the protective effect of flaxseed mucilage on the co-extrusion microencapsulation of Lactobacillus rhamnosus GG. METHODS:Core flow rate, chitosan coating, and flaxseed mucilage concentration were optimised for the microencapsulation of L. rhamnosus. The microbeads were characterised an...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
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更新日期:2020-12-28 00:00:00
abstract::In this study, ethylcellulose and acrylate-methacrylate copolymer (Eudragit RL 100, Eudragit RS 100) membranes were prepared by using appropriate types and amounts of plasticizers. Thirty percent and 20% of triacetin based on polymer weight were found to be appropriate plasticizers for ethylcellulose membranes and acr...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.3109/02652049609026048
更新日期:1996-11-01 00:00:00
abstract::The soft microcapsules containing eucalyptus oil, ubiquinone and the fine water droplets could be prepared with interfacial dehydration reaction between hydroxy methyl cellulose and tannic acid using the water-in-oil-in-water type multiple (W/O)/W emulsion. The diameters of the microcapsules and the content and the mi...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.1080/02652048.2017.1403494
更新日期:2017-12-01 00:00:00