Abstract:
:The bioavailability of marketed nitrofurantoin capsules was compared to capsules filled with Gantrez-gelatin nitrofurantoin microcapsules of a core:coat ratio of 1:2. The collective results obtained from the analysis of urine samples of five volunteers indicated that nitrofurantoin microcapsules provided a prolonged release compared with that of the control formulation. Analysis of variance showed statistically significant differences between the control formulation and the capsule filled with the microcapsule. Non-significant intersubject variation was noticed.
journal_name
J Microencapsuljournal_title
Journal of microencapsulationauthors
Mortada SA,el Egaky MA,Motawi AM,el Khodery KAdoi
10.3109/02652048809036727subject
Has Abstractpub_date
1988-10-01 00:00:00pages
311-7issue
4eissn
0265-2048issn
1464-5246journal_volume
5pub_type
杂志文章abstract::Freeze-drying is an effective way to improve long-term physical stability of nanosuspension in drug delivery applications. Nanosuspension also known as suspension of nanoparticles. In this study, the effect of freeze-drying with different cryoprotectants on the physicochemical characteristics of resveratrol (RSV) nano...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
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更新日期:2018-05-01 00:00:00
abstract::This paper describes a novel approach to prepare and characterize calcium-shellac spheres as a carrier of a tooth whitening agent carbamide peroxide. Calcium-shellac spheres were prepared using an extrusion technique based on dropping aqueous ammonium shellac solution into calcium chloride solution. The effects of for...
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doi:10.1080/02652040802049638
更新日期:2008-12-01 00:00:00
abstract::Protamine-oligonucleotide nanoparticles represent effective colloidal drug carriers for antisense phosphorothioate oligonucleotides (PTO). This study describes improvements in particle preparation and the physicochemical properties of the complexes prepared. The influence of component concentrations, length of the PTO...
journal_title:Journal of microencapsulation
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doi:10.1080/02652040400000504
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abstract::The transport pathway of PBCA nanoparticles through the rabbit cornea and conjunctiva was studied using fluorescence microscopy. Nanoparticles were produced by an emulsion-polymerization process, purified by a GPC procedure, and labelled with rhodamine 6G or propidium iodide as fluorescent laser dyes. The stability of...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.3109/02652049109021873
更新日期:1991-10-01 00:00:00
abstract::The development of solid lipid nanoparticles (SLN) containing all-trans retinoic acid (RA) is an interesting approach to topical treatment of acne. SLN has potential for controlled release and follicular penetration, which can reduce adverse effects in comparison with conventional formulations. However, the encapsulat...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
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abstract::The present research work was aimed at development and optimization of alginate mucoadhesive microspheres of carvedilol for nasal delivery to avoid first pass metabolism and to improve the therapeutic efficacy in the treatment of hypertension and angina pectoris. The microspheres were prepared by a water-in-oil (w/o) ...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
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abstract::Poly(lactic acid) microcapsules of pilocarpine hydrochloride were prepared and evaluated by measuring a miotic effect in rabbits. The microcapsule suspension showed prolongation of miosis and an improved bioavailability when compared with a standard eye dosage form. ...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.3109/02652048509033840
更新日期:1985-10-01 00:00:00
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journal_title:Journal of microencapsulation
pub_type: 杂志文章
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更新日期:2019-11-01 00:00:00
abstract::The present study describes the development of a new cyclosporine formulation based on polycaprolactone (PCL) microspheres (MS) prepared by the solvent evaporation method. Ternary phase diagrams were used to identify the domains where MS were formed. The application of central composite designs established the influen...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
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journal_title:Journal of microencapsulation
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abstract::Gelatin/gum arabic (GA) microcapsules were prepared by a convenient one step complex coacervation, in which TiO2 nanoparticles modified by stearic acid (SA) and homodispersed in tetrachloroethylene (TCE) were encapsulated. The modified TiO2 was characterized by Fourier transform infrared spectroscopy (FT-IR), dynamic ...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
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更新日期:2009-02-01 00:00:00
abstract::Immunomagnetic systems have been used for positive selection of a cell fraction from a mixture using appropriate surface markers with satisfactory results, as haematopoietic CD34+ cells. This work reports on the development of poly(ethylene glycol)-grafted (PEG) immunoliposomes loaded with citrate-magnetite stabilized...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
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更新日期:2001-01-01 00:00:00
abstract::The sorption of 5-fluorouracil from aqueous solutions onto poly(methyl methacrylate) was investigated. Linear sorption isotherms were obtained and no crystallinity of the nanoparticles after sorption was detectable by X-ray analysis indicating a partitioning of the drug into the polymer particles-forming a solid solut...
journal_title:Journal of microencapsulation
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更新日期:1986-04-01 00:00:00
abstract::Optimum conditions for the preparation of non-magnetic and magnetic microspheres of albumin-globulin mix (alglomix) containing mefenamic acid have been standardized. The effect of various parameters has been investigated with regard to the appearance, yield, drug content and encapsulation efficiency. The physicochemic...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.3109/02652049109021856
更新日期:1991-01-01 00:00:00
abstract::Redox-responsive magnetic protein microcapsules with Fe3O4 magnetic nanoparticles (MNPs) encapsulated inside have been obtained using a facile, cost-effective and fast sonochemical method from hen egg white proteins. Such prepared redox-responsive magnetic hen egg white protein microcapsules (MHEWPMCs) could be easily...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
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更新日期:2015-01-01 00:00:00
abstract::This study focuses on development and in vitro characterisation of a nasal delivery system based on uncoated or chitosan-coated solid lipid microparticles (SLMs) containing resveratrol, a natural anti-inflammatory molecule, as an effective alternative to the conventional steroidal drugs. The physico-chemical character...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
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更新日期:2016-12-01 00:00:00
abstract::A considerable effort has been spent in the past three decades to investigate various aspects of liposomes as novel drug delivery systems. In 1990, the first amphotericin B (AmB) liposomal preparation (L-AmB) under the brand name AmBisome was introduced into the market by Vestar. The successful marketing of the produc...
journal_title:Journal of microencapsulation
pub_type: 杂志文章,评审
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更新日期:1998-03-01 00:00:00
abstract::Transplantation of cells genetically modified to produce neurotrophins is a promising spinal cord repair strategy. Previously we showed that fibroblasts engineered to produce brain-derived neurotrophic factor (Fb/BDNF) microencapsulated in alginate survive, continue to grow and express bioactive BDNF. We here compared...
journal_title:Journal of microencapsulation
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更新日期:2011-01-01 00:00:00
abstract::Alginate bead containing calcium carbonate particle were prepared by dropping the suspension of alginate/calcium carbonate (4/1, w/w) into aqueous solution of CaCl(2) (0.1 M). The pH-dependent release property of the bead was observed for 12 h using blue dextran as a model drug. The release increased up to 4 h in a sa...
journal_title:Journal of microencapsulation
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abstract::Documented to exhibit cytotoxicity and poor oral bioavailability, alpha-mangostin was encapsulated into PLGA microspheres with optimization of formulation using response surface methodology. Mixed levels of four factors Face central composite design was employed to evaluate critical formulation variables. With 30 runs...
journal_title:Journal of microencapsulation
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更新日期:2013-01-01 00:00:00
abstract::Monodisperse Ca-alginate microspheres were prepared using the membrane emulsification method. Three ionic types of drugs (anionic, cationic and non-ionic) were incorporated into the microspheres, and the effects of sodium alginate concentration and the pressure applied during the dispersing process on the properties o...
journal_title:Journal of microencapsulation
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abstract::Liposomes containing Isovist were prepared by controlled detergent dialysis as well as by reverse phase evaporation. After preparation these liposomes were lyophilized and then submitted to sterilization by ethylene oxide. Prior to lyophilization, trehalose was added as a protective agent to preserve the size of the l...
journal_title:Journal of microencapsulation
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abstract::Emulsions of menhaden oil and sodium caseinate (NaCas) incorporating carbohydrates of varying dextrose equivalence (DE) were spray-dried to yield encapsulated fish oil powders. The effects of carbohydrate DE (5.5-38), core/wall ratio and NaCas/carbohydrate ratio on microencapsulation efficiency (ME) and oxidative stab...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.1080/0265204031000151974
更新日期:2003-09-01 00:00:00
abstract::A new material for the microencapsulation of biological systems was discovered and characterized with regards to the effects of reaction conditions on product yield. By using poly(cyanoacrylate ester), membrane microcapsules were produced with sufficient strength and porosity to be effective in a process environment f...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.1080/02652040110055225
更新日期:2002-11-01 00:00:00
abstract::Graft copolymer polyethylenimine-graft-poly(N-vinylpyrrolidone) (PEI-g-PVP) was prepared by coupling mono carboxyl-terminated PVP (PVP-COOH) with PEI using N,N'-dicyclohexylcarbodiimide (DCC) and N-hydroxysuccinimide (NHS) as coupling agents. In aqueous medium, PVP-g-PEI can self-assemble into stable polyion complex m...
journal_title:Journal of microencapsulation
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更新日期:2011-01-01 00:00:00
abstract::Phosphatidylcholine (from egg yolk)-cholesterol-stearylamine (7:2:2.25, molar ratio) liposomes when associated with cyclosporin A (phosphatidylcholine:cyclosporin A = 2:0.07, molar ratio) do not inhibit significantly the biosynthesis of [3H]polyglycerophosphatides and [3H]phosphatidylinositol in mitochondrial and micr...
journal_title:Journal of microencapsulation
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更新日期:1989-04-01 00:00:00
abstract::Rosin was esterified with pentaerythritol and intermediate reaction products with different acid values were isolated. Microcapsules containing sulphadiazine were prepared by a solvent evaporation technique using these esters as wall materials. The microcapsules were evaluated for their size, drug content, and release...
journal_title:Journal of microencapsulation
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更新日期:1994-01-01 00:00:00
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journal_title:Journal of microencapsulation
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更新日期:2000-11-01 00:00:00
abstract::N-lauroyl chitosan (NLCS) conjugates with different degrees of substitution (DS) of lauroyl group were synthesized and used to prepare surface modified poly(lactic-co-glycolic) acid (NLCS-PLGA) nanoparticles via hydrophobic interaction and ionic bond force. NLCS-PLGA nanoparticles had spherical shape with shell-core s...
journal_title:Journal of microencapsulation
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doi:10.3109/02652048.2013.824515
更新日期:2014-01-01 00:00:00
abstract::Cross-linked albumin microcapsules were prepared, using a polycondensation interfacial process. Doxorubicin was incorporated in these microcapsules by simple adsorption from aqueous solution. Increasing the extent of cross-linkage of the microcapsule walls by either increasing the cross-linking agent concentration or ...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.3109/02652048809064170
更新日期:1988-07-01 00:00:00