Drug particle size influence on enteric beads produced by a droplet extrusion/precipitation method.

abstract：:Nanoencapsulation by spray drying was performed to protect and preserve antioxidant rich dietary polyphenols from green coffee beans. Nano-encapsulation of green coffee was done using maltodextrin as wall material. The nanoparticles were further characterised by zetasizer, differential scanning colorimetry, X-ray diff...

journal_title：Journal of microencapsulation

authors： Desai NM,Gilbert Stanley J,Murthy PS

更新日期：2020-01-01 00:00:00

abstract：:Chlorogenic acid (CA) is a natural compound used as an antioxidant in the preparation of food, drugs, and cosmetics. Due to their low stability and bioavailability, many researchers have studied the encapsulation of CA in various delivery colloidal systems. The aim of this study was to evaluate the stability of water-...

journal_title：Journal of microencapsulation

authors： Dima C,Dima S

更新日期：2018-09-01 00:00:00

abstract：:Capsules have been prepared based on a polyanion blend of sodium alginate and sodium cellulose sulphate, gelled in the presence of calcium chloride and sodium chloride. In a second step a membrane was formed via the addition of polymethylene-co-guanidine (PMCG), an oligocation. A mechanistic study examined the influen...

journal_title：Journal of microencapsulation

authors： Renken A,Hunkeler D

更新日期：2007-02-01 00:00:00

abstract：:Secretory leukocyte protease inhibitor (SLPI) is an endogenous serine protease inhibitor that protects the lungs from excessive tissue damage caused by leukocyte proteases released during inflammation. Recombinant SLPI (rSLPI) has shown potential as a treatment for inflammatory lung conditions. To date, its clinical a...

journal_title：Journal of microencapsulation

authors： Gibbons AM,McElvaney NG,Taggart CC,Cryan SA

更新日期：2009-09-01 00:00:00

abstract：:This study demonstrates the feasibility of using a single-capillary electrospray (ES) system to generate novel alpha-lipoic acid encapsulated poly(ethylene oxide)-chitosan (ALA/PEO/CS) particles with a monodispersed diameter. Scanning electron microscopic images (SEM) and dynamic light scattering (DLS) results indicat...

journal_title：Journal of microencapsulation

authors： Bai MY,Hu YM

更新日期：2014-01-01 00:00:00

abstract：:Nanoparticles and microspheres made from human serum albumin are biodegradable and, as a physiological material, less cytocidal than cyanoacrylates. Therefore, they should be a suitable carrier system for targeting drugs into cells of the mononuclear phagocyte system. Nevertheless, the process of phagocytic uptake and...

journal_title：Journal of microencapsulation

authors： Schäfer V,von Briesen H,Rübsamen-Waigmann H,Steffan AM,Royer C,Kreuter J

更新日期：1994-05-01 00:00:00

abstract：:Clinical applications of Sesbania grandiflora bark extract (SGE) are limited because of its poor water solubility and stability. SGE was loaded in micelles of Pluronics. In vitro and in vivo antibacterial and toxicity tests were investigated using broth dilution and silkworm model. Aqueous solubility of SGE was improv...

journal_title：Journal of microencapsulation

authors： Anantaworasakul P,Okonogi S

更新日期：2017-02-01 00:00:00

abstract：:Polyisohexylcyanoacrylate nanocapsules containing cyclosporin were prepared by mixing in a 1:2 ratio an oil/ethanol solution of monomer and drug with an aqueous phase. Drug nanoencapsulation rate was controlled by its partition coefficient between the inner (organic) and outer (aqueous) phases. Thus highest encapsulat...

journal_title：Journal of microencapsulation

authors： Bonduelle S,Foucher C,Leroux JC,Chouinard F,Cadieux C,Lenaerts V

更新日期：1992-04-01 00:00:00

abstract：:The degradation of polybutylcyanoacrylate (PBC) and polyhexylcyanoacrylate (PHC) nanoparticles, together with their association with and toxicity towards isolated hepatocytes, were determined. Nanoparticles were not taken up by rat hepatocytes at a significant level. The LD50S of PBC and PHC nanoparticles towards hepa...

journal_title：Journal of microencapsulation

authors： Kreuter J,Wilson CG,Fry JR,Paterson P,Ratcliffe JH

更新日期：1984-07-01 00:00:00

abstract：CONTEXT:Quercetin (QUE) is a flavonoid with antioxidant/anti-inflammatory properties, poorly absorbed when orally administered. OBJECTIVES:To prepare chitosan/xanthan gum microparticles to increase QUE oral bioavailability and optimize its release in the colon. MATERIALS AND METHODS:Chitosan/xanthan gum hydrogel embe...

journal_title：Journal of microencapsulation

authors： Caddeo C,Nácher A,Díez-Sales O,Merino-Sanjuán M,Fadda AM,Manconi M

更新日期：2014-01-01 00:00:00

abstract：AIM:To study the effect of poly(d,l-lactic-co-glycolic acid) (PLGA) microparticles (MPs) preparation techniques on particle physical characterization with special emphasis on burst drug release. METHODS:A basic drug clozapine was used in combination with acid-terminated PLGA. Two approaches for MP preparation were com...

journal_title：Journal of microencapsulation

authors： Ishak RA,Mortada ND,Zaki NM,El-Shamy Ael-H,Awad GA

更新日期：2014-01-01 00:00:00

abstract：:Microencapsulation of ketoprofen using Eudragit RS and RL (acrylic resins) was investigated based on the dispersion system of ketoprofen-containing acetone in liquid paraffin. Aluminium tristearate was used as an additive for the preparation of microcapsules. Good reproducibility was observed in the microencapsulation...

journal_title：Journal of microencapsulation

authors： Goto S,Kawata M,Nakamura M,Maekawa K,Aoyama T

更新日期：1986-10-01 00:00:00

abstract：:Chronic osteomyelitis is still the cause of many problems in orthopaedics in terms of therapy and infection persistence. Four-to-six week systemic antibiotic therapy is required along with bone and soft tissue debridement in the therapy of chronic osteomyelitis. Prolonged-release local antibiotic therapy has been take...

journal_title：Journal of microencapsulation

authors： Yenice I,Caliş S,Atilla B,Kaş HS,Ozalp M,Ekizoğlu M,Bilgili H,Hincal AA

更新日期：2003-11-01 00:00:00

abstract：:The objective of this study was to prepare floating theophylline microspheres with zero order release profiles for use as buoyant reservoirs with increased retention time in the stomach. The microspheres were prepared by a modified emulsion-solvent evaporation method using a polymer mixture of cellulose acetate butyra...

journal_title：Journal of microencapsulation

authors： Stithit S,Chen W,Price JC

更新日期：1998-11-01 00:00:00

abstract：:The purpose of the present study was to provide further insights on the applicability of microencapsulation using emulsification method, to immobilise Clostridium acetobutylicum ATCC 824 spores, for biobutanol production. The encapsulated spores were revived using heat shock treatment and the fermentation efficiency o...

journal_title：Journal of microencapsulation

authors： Rathore S,Wan Sia Heng P,Chan LW

更新日期：2015-01-01 00:00:00

abstract：:PLGA microspheres with high drug loading and high encapsulation efficiency were fabricated by a novel solvent evaporation process-in-situ S/O/W process. Insulin was dissolved in DMSO and dispersed into DCM to form fine particles due to an anti-solvent effect. The in-situ formed suspension was then added into an aqueou...

journal_title：Journal of microencapsulation

authors： Bao W,Zhou J,Luo J,Wu D

更新日期：2006-08-01 00:00:00

abstract：:Bioavailability of oral drugs can be limited by an intestinal excretion process mediated by P-glycoprotein (P-gp). Polyethylene glycol (PEG) is a known P-gp inhibitor. Dispersion of Famotidine (a P-gp substrate) within PEGylated nanoparticles (NPs) was used to improve its oral bioavailability. In this work, we evaluat...

journal_title：Journal of microencapsulation

authors： Mokhtar M,Gosselin P,Lacasse F,Hildgen P

更新日期：2017-02-01 00:00:00

abstract：:Latex particles coated with either amino or carboxyl groups were labelled with 99mTc. Two labelling methods were used: (1) direct labelling with tin reduction and (2) ligand exchange with tin pyrophosphate. Labelling efficiency and the radiochemical impurities were determined by thin-layer chromatography. Effect of [S...

journal_title：Journal of microencapsulation

authors： Ercan MT,Tuncel SA,Caner BE,Pişkin E

更新日期：1993-01-01 00:00:00

abstract：:The purpose of this study was to design and characterise an oral mucoadhesive micellar drug carrier. In this regard, a mucoadhesive hydrophobic cationic aminocellulose was easily synthesised under mild homogeneous conditions with high yield. The cellulose derivative resulted in strongly improved mucoadhesive propertie...

journal_title：Journal of microencapsulation

authors： Songsurang K,Siraleartmukul K,Muangsin N

更新日期：2015-01-01 00:00:00

abstract：:Grapes (Vitis vinifera) are produced in large amounts worldwide and mostly are used for winemaking. Their untreated wastes are rich in valuable secondary metabolites, such as phenolics. Thus, in this study, white and red wine wastes (Malagouzia and Syrah variety) were investigated for their added value phenolics, whic...

journal_title：Journal of microencapsulation

authors： Moschona A,Liakopoulou-Kyriakides M

更新日期：2018-05-01 00:00:00

abstract：:Immunomagnetic systems have been used for positive selection of a cell fraction from a mixture using appropriate surface markers with satisfactory results, as haematopoietic CD34+ cells. This work reports on the development of poly(ethylene glycol)-grafted (PEG) immunoliposomes loaded with citrate-magnetite stabilized...

journal_title：Journal of microencapsulation

authors： Domingo JC,Mercadal M,Petriz J,De Madariaga MA

更新日期：2001-01-01 00:00:00

abstract：:A novel method for preparing the PLGA nanospheres with hydrophilic surface has been designed and characterized. Because of good solubility of tetraglycol in water, PLGA (poly(lactide-co-glycolide)) nanospheres were formed by spraying the PLGA/tetraglycol solution into water. The size of PLGA nanospheres was manipulate...

journal_title：Journal of microencapsulation

authors： Kim BK,Kim D,Cho SH,Yuk SH

更新日期：2004-11-01 00:00:00

abstract：:The effect of process variables such as nozzle size, flow-rate of dispersed phase, inter-electrode distance, and presence of an acid acceptor and a thickening agent in the dispersed phase, on the production and size distribution of nylon 6-10 microcapsules prepared by interfacial polymerization in a high-voltage elect...

journal_title：Journal of microencapsulation

authors： Etuk BR,Weatherley LR,Murray KR

更新日期：1995-03-01 00:00:00

abstract：:Monodisperse albumin microspheres were successfully prepared by both chemical or thermal hardening methods via membrane emulsification using microporous glass membranes with uniform pore sizes. The monodispersity of the microspheres was found to depend strongly on parameters such as albumin concentration, emulsifier c...

journal_title：Journal of microencapsulation

authors： el-Mahdy M,Ibrahim ES,Safwat S,el-Sayed A,Ohshima H,Makino K,Muramatsu N,Kondo T

更新日期：1998-09-01 00:00:00

abstract：:The blood-brain barrier (BBB) is the major problem for the treatment of central nervous system diseases. A previous study from our group showed that the brain-targeted chitosan nanoparticles-loaded with large peptide moieties can rapidly cross the barrier and provide neuroprotection. The present study aims to determin...

journal_title：Journal of microencapsulation

authors： Sahin A,Yoyen-Ermis D,Caban-Toktas S,Horzum U,Aktas Y,Couvreur P,Esendagli G,Capan Y

更新日期：2017-11-01 00:00:00

abstract：:The aim of the present study is to construct a type of polyion complex micelles made of PF127-PEI copolymer and cholic acid (CA) and to evaluate the potential of this type of micelles as a targeted drug delivery system for paclitaxel (PTX). To further improve the targeting capability of micelles, folate was also incor...

journal_title：Journal of microencapsulation

authors： Li Y,Zhou Y,De B,Li L

更新日期：2014-01-01 00:00:00

abstract：:Polyurethane modified with polylactic acid microcapsules were fabricated for controlled release of chlorpyrifos (one of the high usage solid phosphorous insecticides) via interfacial polymerisation with diphenylmethane diisocyanate, polyether triol, 1,4-butanediol and polylactic acid as modifier. The structure, morpho...

journal_title：Journal of microencapsulation

authors： Zheng T,Chen K,Chen W,Wu B,Sheng Y,Xiao Y

更新日期：2019-01-01 00:00:00

abstract：:For slow release of tea tree oil (TTO), TTO were encapsulated by urea-formaldehyde (UF) resin via in situ polymerisation. The effects of curing time and drying condition on particle size, and TTO loading of the TTO/UF microcapsules were investigated. The results indicated that TTO/UF resin microcapsules with curing ti...

journal_title：Journal of microencapsulation

authors： Huang Q,Gong S,Han W,Chen Y,Shu X

更新日期：2020-06-01 00:00:00

abstract：:Microencapsulation is almost exclusively performed in batch processes. With today's chemistry increasingly performed in flow reactors, this work aims to realise a continuous reactor setup for the encapsulation of an ester with a polyuria (PU) shell. The generation of an emulsion template is performed in a recirculatio...

journal_title：Journal of microencapsulation

authors： Gobert SRL,Segers M,Luca S,Teixeira RFA,Kuhn S,Braeken L,Thomassen LCJ

更新日期：2019-06-01 00:00:00

abstract：:The in vivo absorption of crystalline nitrofurantoin and the dosage forms of nitrofurantoin prepared with microcapsules were carried out in man by determination of urinary excretion of unchanged nitrofurantoin. The cumulative amount of drug excreted and the duration of the therapeutic urine levels were compared. The m...

journal_title：Journal of microencapsulation

authors： Ertan G,Karasulu E,Abou-Nada M,Tosun M,Ozer A

更新日期：1994-03-01 00:00:00