Abstract:
:Grapes (Vitis vinifera) are produced in large amounts worldwide and mostly are used for winemaking. Their untreated wastes are rich in valuable secondary metabolites, such as phenolics. Thus, in this study, white and red wine wastes (Malagouzia and Syrah variety) were investigated for their added value phenolics, which were analysed by high performance liquid chromatography (HPLC) and electrospray ionisation-mass spectrometry (ESI/MS) and subsequently encapsulated in several polymers. Extracts from all wastes gave high amounts of total phenolics (13 ± 2.72-22 ± 2.69 mg g-1) and possessed high antioxidant activity (67-97%). In addition to their significant antibacterial activity against gram-negative and gram-positive bacteria, interesting results were also obtained from their anti-inflammatory and antiplatelet activity, in vitro. Encapsulation of the extracts was selective, leaving out most of sugars and other organic compounds when alginate-chitosan was used. Encapsulation efficiency recorded for all extracts ranged from 55% to 79%. Release studies were also performed in several solutions aiming in their commercial use in food and pharmaceutical industries.
journal_name
J Microencapsuljournal_title
Journal of microencapsulationauthors
Moschona A,Liakopoulou-Kyriakides Mdoi
10.1080/02652048.2018.1462415subject
Has Abstractpub_date
2018-05-01 00:00:00pages
229-240issue
3eissn
0265-2048issn
1464-5246journal_volume
35pub_type
杂志文章abstract::Acidic and basic nonsteroidal anti-inflammatory drugs were encapsulated with cellulose derivatives having different functional groups, acidic (carboxymethyl cellulose), basic (chitosan), and neutral (hydroxypropylmethyl cellulose). The properties of the microcapsules were studied and the interaction of the drugs with ...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.3109/02652048909019916
更新日期:1989-07-01 00:00:00
abstract::N-lauroyl chitosan (NLCS) conjugates with different degrees of substitution (DS) of lauroyl group were synthesized and used to prepare surface modified poly(lactic-co-glycolic) acid (NLCS-PLGA) nanoparticles via hydrophobic interaction and ionic bond force. NLCS-PLGA nanoparticles had spherical shape with shell-core s...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.3109/02652048.2013.824515
更新日期:2014-01-01 00:00:00
abstract::A kind of electronic ink, which is supported on indium-tin-oxide (ITO) glass before polymerization, is prepared using urea and formaldehyde resin as wall materials, in which TiO(2) modified with PMMA are dispersed in tetrachloroethylene (TCE) using a mixture of oil blue dyes and charge control additive (span80). Rotar...
journal_title:Journal of microencapsulation
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doi:10.1080/02652040600788197
更新日期:2006-11-01 00:00:00
abstract::Cis-parinaric acid is fluorescent when partioned into a lipid environment and its fluorescence is destroyed upon reaction with free radicals. In our study 1-palmitoyl-2-parinoyl-phosphatidylcholine (cis-PnA) has been used to monitor the time-course of liposomal lipid peroxidation, using reverse-phase evaporation vesic...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.3109/02652049609026029
更新日期:1996-07-01 00:00:00
abstract::The development of microparticulate food particles for marine suspension-feeders is discussed with respect to the difficulties of nutrient delivery in the aquatic environment and to feeding and digestion in crustacea and bivalve molluscs. Loss of nutrients from particles suspended in seawater must be minimized by eith...
journal_title:Journal of microencapsulation
pub_type: 杂志文章,评审
doi:10.3109/02652048509049572
更新日期:1985-01-01 00:00:00
abstract::Freeze-drying is an effective way to improve long-term physical stability of nanosuspension in drug delivery applications. Nanosuspension also known as suspension of nanoparticles. In this study, the effect of freeze-drying with different cryoprotectants on the physicochemical characteristics of resveratrol (RSV) nano...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.1080/02652048.2018.1462416
更新日期:2018-05-01 00:00:00
abstract::The purpose of present research work was to develop mucoadhesive microspheres for nasal delivery with the aim to avoid hepatic first-pass metabolism, improve therapeutic efficacy and enhance residence time. For the treatment of migraine, hydroxypropyl methylcellulose (HPMC) K4M and K15M based microspheres containing s...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.3109/02652040802685241
更新日期:2009-12-01 00:00:00
abstract::Prototype fragrances, prepared from common fragrance components, were extracted with water, recovered, and characterized by gas chromatography before and after the water treatment, revealing a significant loss of the more water-soluble components. Unextracted prototype fragrances were also microencapsulated by a gelat...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.3109/02652049209021244
更新日期:1992-07-01 00:00:00
abstract::In this study, ethylcellulose and acrylate-methacrylate copolymer (Eudragit RL 100, Eudragit RS 100) membranes were prepared by using appropriate types and amounts of plasticizers. Thirty percent and 20% of triacetin based on polymer weight were found to be appropriate plasticizers for ethylcellulose membranes and acr...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.3109/02652049609026048
更新日期:1996-11-01 00:00:00
abstract::The effect of lecithin and starch on viability of alginate encapsulated probiotics was determined at different temperatures. Probiotic organisms (1% v/v>10Log CFU ml(-1)) were encapsulated using alginate (2% w/v), gelatinized starches (2% w/v) and lecithin (0-4% w/v) and stored in sealed containers at 4, 23 and 37 deg...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.3109/02652040902982183
更新日期:2010-01-01 00:00:00
abstract::Poly(lactic acid) microcapsules of pilocarpine hydrochloride were prepared and evaluated by measuring a miotic effect in rabbits. The microcapsule suspension showed prolongation of miosis and an improved bioavailability when compared with a standard eye dosage form. ...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.3109/02652048509033840
更新日期:1985-10-01 00:00:00
abstract::For slow release of tea tree oil (TTO), TTO were encapsulated by urea-formaldehyde (UF) resin via in situ polymerisation. The effects of curing time and drying condition on particle size, and TTO loading of the TTO/UF microcapsules were investigated. The results indicated that TTO/UF resin microcapsules with curing ti...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.1080/02652048.2020.1735548
更新日期:2020-06-01 00:00:00
abstract::The present study is part of a larger project whose aim is to understand how the oyster Crassostrea gigas develops its aromas from a lipid precursor, the eicosapentaenoic acid (EPA), in glyceride form. The objective of this study is, therefore, to prepare an encapsulation process that will enable the bivalve to be sup...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:
更新日期:2003-01-01 00:00:00
abstract:PURPOSE:Naproxen CR tablets have been obtained from its microspheres prepared by coprecipitation with Eudragit L100-55. The purpose of this work was to evaluate the main and interaction effects of deaggregating agent concentration (X1), compression pressure (X2) and amount of precipitating water (X3) on naproxen releas...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.1080/02652040110055630
更新日期:2001-09-01 00:00:00
abstract::Alginate bead containing calcium carbonate particle were prepared by dropping the suspension of alginate/calcium carbonate (4/1, w/w) into aqueous solution of CaCl(2) (0.1 M). The pH-dependent release property of the bead was observed for 12 h using blue dextran as a model drug. The release increased up to 4 h in a sa...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.1080/02652040701657820
更新日期:2007-12-01 00:00:00
abstract::Palmatine (PM) is a potent anti-infective agent used to treat eye diseases. However, PM is less effective for ocular application due to short residence time within the eyes. This study aimed to develop a cationic lipid emulsions (CLEs) for ophthalmic delivery of PM and evaluate its suitability in infection treatment. ...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.1080/02652048.2016.1248512
更新日期:2016-12-01 00:00:00
abstract::Nanoparticles and microspheres made from human serum albumin are biodegradable and, as a physiological material, less cytocidal than cyanoacrylates. Therefore, they should be a suitable carrier system for targeting drugs into cells of the mononuclear phagocyte system. Nevertheless, the process of phagocytic uptake and...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.3109/02652049409040455
更新日期:1994-05-01 00:00:00
abstract::This work investigated the means for the efficient encapsulation of muramyl dipeptide (MDP) in poly(epsilon-caprolactone) (PCL) microparticles (MP) by a solvent evaporation method in order to optimize the effect of the adjuvant for oral immunization. Therefore, the influence of MDP concentration in the inner aqueous p...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.1080/026520499288799
更新日期:1999-09-01 00:00:00
abstract::In the previous report, microencapsulation of lipase employing a (w/o)/w multiple phase emulsion technique, with 2:1 polystyrene (PS)-SBR mixture being used as a wall material, was proposed. Catalysis of the encapsulated enzyme was investigated, and the hydrolysis of triacetin (triglyceride of acetic acid) was success...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.3109/02652048909019911
更新日期:1989-07-01 00:00:00
abstract::Biodegradable polymers for localized delivery of antibiotics have emerged as an important approach to treating orthopaedic infections. In chronic forms of osteomyelitis which are thought to be associated with bacterial biofilm, localized delivery of a suitable antibiotic is desirable. This paper describes the formulat...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
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更新日期:1999-01-01 00:00:00
abstract::The aim of this work was to investigate the role of HLB of emulsifier as well as volume of the internal aqueous phase (W(1)) and presence of salt in the external aqueous phase (W(2)) on the morphology, size and encapsulation efficiency of poly(D,L-lactide) microspheres containing naltrexone HCl. PLA microparticles con...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
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更新日期:2005-03-01 00:00:00
abstract::Hyaluronidase is a protein whose enzymatic activity is successfully employed in extravasation therapy. Taking into account that several proteins (e.g. gelatin and albumin) have been employed as natural polymers for the preparation of microspheres, this work approaches a comprehensive investigation on hyaluronidase inj...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.3109/02652049809006838
更新日期:1998-01-01 00:00:00
abstract::Documented to exhibit cytotoxicity and poor oral bioavailability, alpha-mangostin was encapsulated into PLGA microspheres with optimization of formulation using response surface methodology. Mixed levels of four factors Face central composite design was employed to evaluate critical formulation variables. With 30 runs...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.3109/02652048.2013.788081
更新日期:2013-01-01 00:00:00
abstract::Insulin-loaded solid lipid nanoparticles (SLN), obtained by the solvent-in-water emulsion-diffusion technique, were produced using isovaleric acid (IVA) as organic phase, glyceryl mono-stearate (GMS) as lipid, soy lecithin and sodium taurodeoxycholate (TDC) as emulsifiers. IVA, a partially water-miscible solvent with ...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.1080/02652040701532981
更新日期:2007-11-01 00:00:00
abstract::The factors influencing the encapsulation of azathioprine (AZA) into liposomes were investigated to find out the conditions for its optimal entrapment. Similar studies for comparison were also carried out on 6-mercaptopurine (6-MP), of which AZA is a prodrug. AZA and also 6-MP show higher encapsulation efficiencies in...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.3109/02652049809006875
更新日期:1998-07-01 00:00:00
abstract::Sequential interpenetrating networks of poly(methacrylic acid) and poly(vinyl alcohol) have been prepared and cross-linked with glutaraldehyde to obtain pH sensitive microspheres by a water-in-oil emulsification method. Microspheres have been used to deliver the chosen model anti-inflammatory drug viz., ibuprofen to t...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.1080/02652040801896435
更新日期:2008-06-01 00:00:00
abstract:AIMS:This study was aimed to develop Isotretinoin (ITN) and α-tocopherol acetate (α-TA) loaded solid lipid nanoparticle topical gel for better skin sensitivity and potentiation of efficacy. METHODS:ITN and α-TA-loaded solid lipid nanoparticles (AE-SLN) were prepared by microemulsion method with glyceryl mono-stearate ...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.1080/02652048.2020.1823499
更新日期:2020-12-01 00:00:00
abstract::This study optimized and evaluated the conditions for surface coating of microspheres using a spray-dryer. Four formulations of Bromophenol blue (BPB)-loaded albumin microspheres were prepared using a spray-dryer, cross-linked at different concentrations and time periods. One of the optimized formulations with the des...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.1080/02652040802476187
更新日期:2008-12-01 00:00:00
abstract::Aim: A novel folated pluronic F127 (FA-F127) was synthesised, so as to modify liposomes with FA group on the surface, and evaluate the effects of FA-F127 modification on the properties of the modified liposomes.Methods: FA was linked to one end of pluronic F127, via the terminal OH group, to obtain FA-F127 and the str...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.1080/02652048.2020.1720030
更新日期:2020-05-01 00:00:00
abstract::The purpose of this study was the preparation, optimisation and in vitro characterisation of PHBV and PLGA blend nanoparticles (NPs) for prolonged delivery of Teriparatide. Double emulsion solvent evaporation technique was employed for the fabrication of NPs. The nanoformulation was optimised using the Box-Behnken met...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.1080/02652048.2016.1208296
更新日期:2016-08-01 00:00:00