Development of a new solid lipid nanoparticle formulation containing retinoic acid for topical treatment of acne.

abstract：:To improve poor water solubility of cyclosporine A (CsA), hydroxypropyl-beta-cyclodextrin (HPβCD) was incorporated into the nanoparticle formulation. Solid complexes of CsA with HPβCD in different ratios were prepared by the kneading method. CsA containing alone or in combination with HPβCD in poly-lactide-co-glycolid...

journal_title：Journal of microencapsulation

authors： Aksungur P,Demirbilek M,Denkbaş EB,Unlü N

更新日期：2012-01-01 00:00:00

abstract：:To prepare the sustained release vitamin C carriers, vitamin C was successfully encapsulated in tripolyphosphate (TPP) cross-linked chitosan (TPP-chitosan) microspheres by the spray-drying method at different manufacturing conditions. Manufacturing parameters (inlet temperature, liquid flow rate, chitosan concentratio...

journal_title：Journal of microencapsulation

authors： Desai KG,Park HJ

更新日期：2006-02-01 00:00:00

abstract：:Proliposomes of ibuprofen were successfully prepared using effervescent granules as solid carriers of dried phospholipids along with other lipids (soyabean lecithin, stearylamine and cholesterol). Liposomes of regular size with uniform size distribution resulted when proliposomal formulations were hydrated under the e...

journal_title：Journal of microencapsulation

authors： Katare OP,Vyas SP,Dixit VK

更新日期：1990-10-01 00:00:00

abstract：:This article describes the physicochemical properties of chitosan-coated liposomes containing skin-protecting agents, coenzyme Q10 and alpha-lipoic acid (CCAL). CCAL had a spherical shell-core structure and liposomes inverted the surface charge from negative to positive after coating with chitosan. Compared with the u...

journal_title：Journal of microencapsulation

authors： Zhao GD,Sun R,Ni SL,Xia Q

更新日期：2015-01-01 00:00:00

abstract：PURPOSE:To develop a stable and reproducible modified release pellet formulation containing ibuprofen. METHODS:Using extrusion-spheronization technology to produce pellets. RESULTS:The percentage yield, size distribution and overall pellet shape within the desired size range of 1000-1400 microm was found to be depend...

journal_title：Journal of microencapsulation

authors： Lutchman D,Dangor CM,Perumal D

更新日期：2005-09-01 00:00:00

abstract：:The purpose of the present study was to provide further insights on the applicability of microencapsulation using emulsification method, to immobilise Clostridium acetobutylicum ATCC 824 spores, for biobutanol production. The encapsulated spores were revived using heat shock treatment and the fermentation efficiency o...

journal_title：Journal of microencapsulation

authors： Rathore S,Wan Sia Heng P,Chan LW

更新日期：2015-01-01 00:00:00

abstract：:Poly(lactic acid) microcapsules of pilocarpine hydrochloride were prepared and evaluated by measuring a miotic effect in rabbits. The microcapsule suspension showed prolongation of miosis and an improved bioavailability when compared with a standard eye dosage form. ...

journal_title：Journal of microencapsulation

authors： Vidmar V,Pepeljnjak S,Jalsenjak I

更新日期：1985-10-01 00:00:00

abstract：:Microencapsulation is almost exclusively performed in batch processes. With today's chemistry increasingly performed in flow reactors, this work aims to realise a continuous reactor setup for the encapsulation of an ester with a polyuria (PU) shell. The generation of an emulsion template is performed in a recirculatio...

journal_title：Journal of microencapsulation

authors： Gobert SRL,Segers M,Luca S,Teixeira RFA,Kuhn S,Braeken L,Thomassen LCJ

更新日期：2019-06-01 00:00:00

abstract：:In this study, ethylcellulose and acrylate-methacrylate copolymer (Eudragit RL 100, Eudragit RS 100) membranes were prepared by using appropriate types and amounts of plasticizers. Thirty percent and 20% of triacetin based on polymer weight were found to be appropriate plasticizers for ethylcellulose membranes and acr...

journal_title：Journal of microencapsulation

authors： Nimmannit U,Suwanpatra N

更新日期：1996-11-01 00:00:00

abstract：:Polyurethane modified with polylactic acid microcapsules were fabricated for controlled release of chlorpyrifos (one of the high usage solid phosphorous insecticides) via interfacial polymerisation with diphenylmethane diisocyanate, polyether triol, 1,4-butanediol and polylactic acid as modifier. The structure, morpho...

journal_title：Journal of microencapsulation

authors： Zheng T,Chen K,Chen W,Wu B,Sheng Y,Xiao Y

更新日期：2019-01-01 00:00:00

abstract：:The factors influencing the encapsulation of azathioprine (AZA) into liposomes were investigated to find out the conditions for its optimal entrapment. Similar studies for comparison were also carried out on 6-mercaptopurine (6-MP), of which AZA is a prodrug. AZA and also 6-MP show higher encapsulation efficiencies in...

journal_title：Journal of microencapsulation

authors： Gulati M,Grover M,Singh M,Singh S

更新日期：1998-07-01 00:00:00

abstract：:The influence of drug particle size on the production of enteric beads by a polymer precipitation technique was investigated. Drug particle dimensions are known to play an important role in most microencapsulation techniques. Bead morphology was greatly influenced by drug particle size, and spherical shaped beads coul...

journal_title：Journal of microencapsulation

authors： Cerdeira AM,Gouveia LF,Goucha P,Almeida AJ

更新日期：2000-11-01 00:00:00

abstract：:The aim of the present study is to construct a type of polyion complex micelles made of PF127-PEI copolymer and cholic acid (CA) and to evaluate the potential of this type of micelles as a targeted drug delivery system for paclitaxel (PTX). To further improve the targeting capability of micelles, folate was also incor...

journal_title：Journal of microencapsulation

authors： Li Y,Zhou Y,De B,Li L

更新日期：2014-01-01 00:00:00

abstract：:A kind of electronic ink, which is supported on indium-tin-oxide (ITO) glass before polymerization, is prepared using urea and formaldehyde resin as wall materials, in which TiO(2) modified with PMMA are dispersed in tetrachloroethylene (TCE) using a mixture of oil blue dyes and charge control additive (span80). Rotar...

journal_title：Journal of microencapsulation

authors： Wang YT,Zhao XP,Wang DW

更新日期：2006-11-01 00:00:00

abstract：:The purpose of this study was the preparation, optimisation and in vitro characterisation of PHBV and PLGA blend nanoparticles (NPs) for prolonged delivery of Teriparatide. Double emulsion solvent evaporation technique was employed for the fabrication of NPs. The nanoformulation was optimised using the Box-Behnken met...

journal_title：Journal of microencapsulation

authors： Bahari Javan N,Rezaie Shirmard L,Jafary Omid N,Akbari Javar H,Rafiee Tehrani M,Abedin Dorkoosh F

更新日期：2016-08-01 00:00:00

abstract：:Sequential interpenetrating networks of poly(methacrylic acid) and poly(vinyl alcohol) have been prepared and cross-linked with glutaraldehyde to obtain pH sensitive microspheres by a water-in-oil emulsification method. Microspheres have been used to deliver the chosen model anti-inflammatory drug viz., ibuprofen to t...

journal_title：Journal of microencapsulation

authors： Mundargi RC,Patil SA,Kulkarni PV,Mallikarjuna NN,Aminabhavi TM

更新日期：2008-06-01 00:00:00

abstract：:The aim was to study the effect of the type of polymer solvent on characteristics of microspheres produced by spray drying. The water-soluble model protein, bovine serum albumin (BSA) was microencapsulated into biodegradable poly(D,L-lactic acid) using the following 10 different polymer solvents: acetaldehyde dimethyl...

journal_title：Journal of microencapsulation

authors： Gander B,Wehrli E,Alder R,Merkle HP

更新日期：1995-01-01 00:00:00

abstract：AIM:To develop a biocompatible cobalt ferrite (CF-NP) nanodrug formulation using oleic acid and poly (d,l-lactide-co-glycolic) acid (PLGA) for the delivery of docetaxel (DTX) specifically to breast cancer cells. METHODS:The CF-NP were synthesised by hydrothermal method and conjugated with DTX in a PLGA matrix and were...

journal_title：Journal of microencapsulation

authors： Panda J,Satapathy BS,Mandal B,Sen R,Mukherjee B,Sarkar R,Tudu B

更新日期：2021-01-01 00:00:00

abstract：:Cross-linked albumin microcapsules were prepared, using a polycondensation interfacial process. Doxorubicin was incorporated in these microcapsules by simple adsorption from aqueous solution. Increasing the extent of cross-linkage of the microcapsule walls by either increasing the cross-linking agent concentration or ...

journal_title：Journal of microencapsulation

authors： Sawaya A,Fickat R,Benoit JP,Puisieux F,Benita S

更新日期：1988-07-01 00:00:00

abstract：:An extrusion-based encapsulation process has been developed for making salt grain-sized iron premix for salt fortification. The first step of extrusion agglomeration process has been studied and reported previously. The focus of this study is on the optimisation of the colour-masking and polymer coating steps. Several...

journal_title：Journal of microencapsulation

authors： Yadava D,Olive Li Y,Diosady LL,Wesley AS

更新日期：2012-01-01 00:00:00

abstract：:Secretory leukocyte protease inhibitor (SLPI) is an endogenous serine protease inhibitor that protects the lungs from excessive tissue damage caused by leukocyte proteases released during inflammation. Recombinant SLPI (rSLPI) has shown potential as a treatment for inflammatory lung conditions. To date, its clinical a...

journal_title：Journal of microencapsulation

authors： Gibbons AM,McElvaney NG,Taggart CC,Cryan SA

更新日期：2009-09-01 00:00:00

abstract：:Drug-free polylactic acid (PLA) microspheres were prepared by an emulsification-solvent evaporation technique using different types of protective colloids. The influence of five types of hydrophilic prolymers (polysaccharides, proteins, synthetic cellulose derivatives, synthetic nonionic polymers and surfactants) on t...

journal_title：Journal of microencapsulation

authors： Lin SY,Chen KS,Teng HH

更新日期：1998-05-01 00:00:00

abstract：:The objective of this study is to explore the influence of polyvinylpyrrolidone (PVP) quantity on the solubility, crystallinity and oral bioavailability of poorly water-soluble fenofibrate in solvent-evaporated microspheres. Numerous microspheres were prepared with fenofibrate, sodium lauryl sulphate (SLS) and PVP usi...

journal_title：Journal of microencapsulation

authors： Yousaf AM,Kim DW,Kim DS,Kim JO,Youn YS,Cho KH,Yong CS,Choi HG

更新日期：2016-06-01 00:00:00

abstract：:In this study, we formulated a microparticulate melanoma cancer vaccine via the transdermal route. The vaccine was delivered using microneedle-based Dermaroller® which is available for cosmetic purposes. Unlike subcutaneous injections, administration using microneedles is painless and in general can increase the perme...

journal_title：Journal of microencapsulation

authors： Bhowmik T,D'Souza B,Shashidharamurthy R,Oettinger C,Selvaraj P,D'Souza MJ

更新日期：2011-01-01 00:00:00

abstract：:A considerable effort has been spent in the past three decades to investigate various aspects of liposomes as novel drug delivery systems. In 1990, the first amphotericin B (AmB) liposomal preparation (L-AmB) under the brand name AmBisome was introduced into the market by Vestar. The successful marketing of the produc...

journal_title：Journal of microencapsulation

authors： Gulati M,Bajad S,Singh S,Ferdous AJ,Singh M

更新日期：1998-03-01 00:00:00

abstract：:Rosin was esterified with pentaerythritol and intermediate reaction products with different acid values were isolated. Microcapsules containing sulphadiazine were prepared by a solvent evaporation technique using these esters as wall materials. The microcapsules were evaluated for their size, drug content, and release...

journal_title：Journal of microencapsulation

authors： Sheorey DS,Dorle AK

更新日期：1994-01-01 00:00:00

abstract：:Water-in-oil-in-water multiple emulsions of chloroquine diphosphate were prepared, using olive oil, arachis oil, Span 80, gelatin, acacia and Tween 80. Emulsifiers were employed individually or in combination. An attempt was made to correlate preparative variables with stability and drug release of multiple emulsions ...

journal_title：Journal of microencapsulation

authors： Vaziri A,Warburton B

更新日期：1994-11-01 00:00:00

abstract：:This study explored a liquid phase coating technique to produce polymethyl methacrylate (PMMA)-coated alginate microspheres. Alginate microspheres with a mean diameter of 85.6 microm were prepared using an emulsification method. The alginate microspheres, as cores, were then coated with different types of PMMA by a li...

journal_title：Journal of microencapsulation

authors： Chan LW,Liu X,Heng PW

更新日期：2005-12-01 00:00:00

abstract：:H-n.m.r. spectroscopy of small unilamellar phospholipid vesicles in the presence of the lanthanide probe ion Dy3+ has been used to study the permeability of these liposomes induced by the bile salts (glycocholate and glycodeoxycholate) and pancreatic phospholipase A2. A marked synergism is demonstrated in the combined...

journal_title：Journal of microencapsulation

authors： Hunt GR,Jones IC

更新日期：1984-04-01 00:00:00

abstract：:Bioavailability of oral drugs can be limited by an intestinal excretion process mediated by P-glycoprotein (P-gp). Polyethylene glycol (PEG) is a known P-gp inhibitor. Dispersion of Famotidine (a P-gp substrate) within PEGylated nanoparticles (NPs) was used to improve its oral bioavailability. In this work, we evaluat...

journal_title：Journal of microencapsulation

authors： Mokhtar M,Gosselin P,Lacasse F,Hildgen P

更新日期：2017-02-01 00:00:00