Influence of polyvinylpyrrolidone quantity on the solubility, crystallinity and oral bioavailability of fenofibrate in solvent-evaporated microspheres.

abstract：:Clinical applications of Sesbania grandiflora bark extract (SGE) are limited because of its poor water solubility and stability. SGE was loaded in micelles of Pluronics. In vitro and in vivo antibacterial and toxicity tests were investigated using broth dilution and silkworm model. Aqueous solubility of SGE was improv...

journal_title：Journal of microencapsulation

authors： Anantaworasakul P,Okonogi S

更新日期：2017-02-01 00:00:00

abstract：:Gelatin/gum arabic (GA) microcapsules were prepared by a convenient one step complex coacervation, in which TiO2 nanoparticles modified by stearic acid (SA) and homodispersed in tetrachloroethylene (TCE) were encapsulated. The modified TiO2 was characterized by Fourier transform infrared spectroscopy (FT-IR), dynamic ...

journal_title：Journal of microencapsulation

authors： Wang DW,Zhao XP

更新日期：2009-02-01 00:00:00

abstract：:Microspheres, including microcapsules and cells or beads, are widely used to produce many functional products. Information about their mechanical properties is essential to understanding their performance during manufacturing, processing and end-use applications. The mechanical characterization of microspheres require...

journal_title：Journal of microencapsulation

authors： Mercadé-Prieto R,Zhang Z

更新日期：2012-01-01 00:00:00

abstract：:A considerable effort has been spent in the past three decades to investigate various aspects of liposomes as novel drug delivery systems. In 1990, the first amphotericin B (AmB) liposomal preparation (L-AmB) under the brand name AmBisome was introduced into the market by Vestar. The successful marketing of the produc...

journal_title：Journal of microencapsulation

authors： Gulati M,Bajad S,Singh S,Ferdous AJ,Singh M

更新日期：1998-03-01 00:00:00

abstract：:This work demonstrates Box-Behnken design (BBD)'s capability in exploring scientific principles governing a process, different from its use in process optimisation. We have investigated nanoprecipitation (NP) of temozolomide with polycaprolactone. Five factors, surfactant, stirring speed (SS), dropping rate (DR), phas...

journal_title：Journal of microencapsulation

authors： Singh Y,Ojha P,Srivastava M,Chourasia MK

更新日期：2015-01-01 00:00:00

abstract：:The objective of this work was to prepare and evaluate ketoprofen-loaded albumin microspheres for intramuscular administration. Microspheres were prepared by emulsion cross-linking method using a 2(3) factorial design and the effect of different factors on entrapment efficiency was determined. Microspheres were evalua...

journal_title：Journal of microencapsulation

authors： Mathew ST,Devi SG,Prasanth VV,Vinod B

更新日期：2009-08-01 00:00:00

abstract：:Multilamellar liposomes incorporating essential oil of Brazilian cherry (Eugenia uniflora L.) leaves were produced by dry film hydration. Gas chromatography demonstrated the compounds found in the essential oil were effectively incorporated in the aqueous dispersions of liposomes. Differential scanning calorimetry ana...

journal_title：Journal of microencapsulation

authors： Yoshida PA,Yokota D,Foglio MA,Rodrigues RA,Pinho SC

更新日期：2010-01-01 00:00:00

abstract：:The development of solid lipid nanoparticles (SLN) containing all-trans retinoic acid (RA) is an interesting approach to topical treatment of acne. SLN has potential for controlled release and follicular penetration, which can reduce adverse effects in comparison with conventional formulations. However, the encapsulat...

journal_title：Journal of microencapsulation

authors： Castro GA,Oréfice RL,Vilela JM,Andrade MS,Ferreira LA

更新日期：2007-08-01 00:00:00

abstract：:In this study, recombinant human interleukin-2 (rhIL-2) containing poly(lactic-co-glycolic acid) (PLGA) microparticles were prepared for pulmonary administration by modified w/o/w double emulsion solvent extraction method and the effects of various formulation parameters on the physicochemical properties of the microp...

journal_title：Journal of microencapsulation

authors： Devrim B,Bozkir A,Canefe K

更新日期：2011-01-01 00:00:00

abstract：:Poly(lactic acid) microcapsules of pilocarpine hydrochloride were prepared and evaluated by measuring a miotic effect in rabbits. The microcapsule suspension showed prolongation of miosis and an improved bioavailability when compared with a standard eye dosage form. ...

journal_title：Journal of microencapsulation

authors： Vidmar V,Pepeljnjak S,Jalsenjak I

更新日期：1985-10-01 00:00:00

abstract：:This study explored a liquid phase coating technique to produce polymethyl methacrylate (PMMA)-coated alginate microspheres. Alginate microspheres with a mean diameter of 85.6 microm were prepared using an emulsification method. The alginate microspheres, as cores, were then coated with different types of PMMA by a li...

journal_title：Journal of microencapsulation

authors： Chan LW,Liu X,Heng PW

更新日期：2005-12-01 00:00:00

abstract：:Microparticles with different essential oil concentrations 0, 75, 150, 225 and 300 gkg-1, (g of essential oil per kg of microparticles), were produced by dispersing the essential oils within a hydrogenated vegetable fat matrix and forming spherical solid particles by spray-chilling. Size distribution, flowability, sur...

journal_title：Journal of microencapsulation

authors： Gottschalk P,Brodesser B,Poncelet D,Jaeger H,Rennhofer H,Cole S

更新日期：2018-09-01 00:00:00

abstract：:Vascular endothelial growth factor receptor (VEGFR) is over-expressed on a variety of tumour cells and tumour neovasculature, and so becomes well-documented target for cancer treatment. This study was designed to evaluate the cellular targeting and anti-tumor potency of VEGF-conjugated nanoparticles (VEGF-NPs). The po...

journal_title：Journal of microencapsulation

authors： Shi Y,Zhou M,Zhang J,Lu W

更新日期：2015-01-01 00:00:00

abstract：:The regularities of release of therapeutic antioxidant enzyme superoxide dismutase (SOD) from various alginate-based delivery systems (DS) into simulated gastric and intestinal fluids were determined. The following systems were used: Ca-alginate granules (AG) prepared by various methods, porous carbonate cores with mu...

journal_title：Journal of microencapsulation

authors： Sudareva N,Suvorova O,Saprykina N,Vilesov A,Bel'tyukov P,Petunov S

更新日期：2016-08-01 00:00:00

abstract：:Polylactide (PLA) and polylactide-co-glycolide (PLGA) particles entrapping rotavirus (strain SA11) were formulated using a solvent evaporation technique. To minimize denaturation of viral antigen during the emulsification process, serum albumin was used as a stabilizer. Use of NaHCO(3) and sucrose during the primary e...

journal_title：Journal of microencapsulation

authors： Nayak B,Panda AK,Ray P,Ray AR

更新日期：2009-03-01 00:00:00

abstract：:Optimum conditions for the preparation of non-magnetic and magnetic microspheres of albumin-globulin mix (alglomix) containing mefenamic acid have been standardized. The effect of various parameters has been investigated with regard to the appearance, yield, drug content and encapsulation efficiency. The physicochemic...

journal_title：Journal of microencapsulation

authors： Lalla JK,Ahuja PL

更新日期：1991-01-01 00:00:00

abstract：:Abietic acid was isolated from rosin N Grade (ISI) by a simple process and the product was further standardized. Sulphadiazine microcapsules were prepared by the solvent evaporation technique, using abietic acid as a wall-forming material. Discrete, spherical and free-flowing microcapsules were obtained by phase separ...

journal_title：Journal of microencapsulation

authors： Puranik PK,Manekar NC,Dorle AK

更新日期：1992-10-01 00:00:00

abstract：:Transplantation of cells genetically modified to produce neurotrophins is a promising spinal cord repair strategy. Previously we showed that fibroblasts engineered to produce brain-derived neurotrophic factor (Fb/BDNF) microencapsulated in alginate survive, continue to grow and express bioactive BDNF. We here compared...

journal_title：Journal of microencapsulation

authors： Francis NL,Shanbhag MS,Fischer I,Wheatley MA

更新日期：2011-01-01 00:00:00

abstract：:Insulin-loaded solid lipid nanoparticles (SLN), obtained by the solvent-in-water emulsion-diffusion technique, were produced using isovaleric acid (IVA) as organic phase, glyceryl mono-stearate (GMS) as lipid, soy lecithin and sodium taurodeoxycholate (TDC) as emulsifiers. IVA, a partially water-miscible solvent with ...

journal_title：Journal of microencapsulation

authors： Battaglia L,Trotta M,Gallarate M,Carlotti ME,Zara GP,Bargoni A

更新日期：2007-11-01 00:00:00

abstract：:Objective: To improve the water solubility and enhance the oral bioavailability of gambogenic acid (GNA). Methods: GNA-phospholipid complex (GNA-PLC) micelles were successfully prepared by anti-solvent method. Results: The encapsulation efficiency of GNA-PLC micelles can reach 99.33 % (w/w). The average particle size ...

journal_title：Journal of microencapsulation

authors： Wang B,Cheng W,Zhang C,Bao Y,Zha L,Qian J,Hong L,Chen W

更新日期：2019-09-01 00:00:00

abstract：:For the preparation of microcapsules using the W/O/W (water in oil in water) emulsion system, it is essential to control various factors such as the dispersed state of the organic phase in the W/O/W emulsion, the difference in the solute concentration between the inner and outer aqueous phases and the volume fraction ...

journal_title：Journal of microencapsulation

authors： Kiyoyama S,Shiomori K,Kawano Y,Hatate Y

更新日期：2003-07-01 00:00:00

abstract：:Grapes (Vitis vinifera) are produced in large amounts worldwide and mostly are used for winemaking. Their untreated wastes are rich in valuable secondary metabolites, such as phenolics. Thus, in this study, white and red wine wastes (Malagouzia and Syrah variety) were investigated for their added value phenolics, whic...

journal_title：Journal of microencapsulation

authors： Moschona A,Liakopoulou-Kyriakides M

更新日期：2018-05-01 00:00:00

abstract：:Isoniazid was encapsulated into microspheres of alginate-chitosan by means of a complex coacervation method in an emulsion system. Since the encapsulation of isoniazid tends to be limited by its hydrophilic characteristics, this study proposes its microencapsulation by adsorption. The particles were prepared in three ...

journal_title：Journal of microencapsulation

authors： Lucinda-Silva RM,Evangelista RC

更新日期：2003-03-01 00:00:00

abstract：:Solid lipid nanoparticles (SLNs) and nanosuspensions (NSs) have shown great promise for improving bioavailability of poorly water-soluble drugs. This study was aimed to develop SLNs and NS of Saquinavir (SQ) for improvement in bioavailability. These formulations were characterized and their pharmacokinetics and biodis...

journal_title：Journal of microencapsulation

authors： Dodiya SS,Chavhan SS,Sawant KK,Korde AG

更新日期：2011-01-01 00:00:00

abstract：:Sub-100-nm nanoparticles were prepared from beta-lactoglobulin (BLG) with a narrow size distribution by a desolvation method using glutaraldehyde for cross-linking. With pre-heating of the BLG solution to 60 degrees C and subsequent pH readjustment to 9.0, nanoparticles of 59 +/- 5 nm were obtained with improved unifo...

journal_title：Journal of microencapsulation

authors： Ko S,Gunasekaran S

更新日期：2006-12-01 00:00:00

abstract：:The purpose of this study was the preparation, optimisation and in vitro characterisation of PHBV and PLGA blend nanoparticles (NPs) for prolonged delivery of Teriparatide. Double emulsion solvent evaporation technique was employed for the fabrication of NPs. The nanoformulation was optimised using the Box-Behnken met...

journal_title：Journal of microencapsulation

authors： Bahari Javan N,Rezaie Shirmard L,Jafary Omid N,Akbari Javar H,Rafiee Tehrani M,Abedin Dorkoosh F

更新日期：2016-08-01 00:00:00

abstract：:The microencapsulation of drugs is gaining importance in many research activities. A common technique for preparing microcapsules is the solvent evaporation method which is simple but has a large number of reaction control parameters. This study reports the microcapsulation of allopurinol by the solvent evaporation me...

journal_title：Journal of microencapsulation

authors： Arabi H,Hashemi SA,Fooladi M

更新日期：1996-09-01 00:00:00

abstract：:Provision and maintenance of adequate concentrations of antibiotics at infection sites is very important in treating highly resistant infections. For diseases like implant related osteomyelitis (IRO) it is best to provide this locally via implanted drug formulations, as systemic administration of the antibiotic may no...

journal_title：Journal of microencapsulation

authors： Gurselt I,Yagmurlu F,Korkusuz F,Hasirci V

更新日期：2002-03-01 00:00:00

abstract：:Enteric diastase spherules were prepared using cellulose acetate phthalate and eudragit RS-100 by emulsion solvent removal method. Factors that could affect the size shape and diastatic activity were studied. The studied factors include pH of aqueous media, temperature of dispersion media and concentration of surface ...

journal_title：Journal of microencapsulation

authors： Vyas SP,Gogoi PJ,Pande S,Dixit VK

更新日期：1991-10-01 00:00:00

abstract：:The primary objective was to synthesize a novel wound dressing containing basic fibroblast growth factor (bFGF)-loaded microspheres for promoting healing and tissue regeneration. Gelatin sponge was chosen as the underlying layer and elastomeric polyurethane membranes were used as the external layer. To achieve prolong...

journal_title：Journal of microencapsulation

authors： Huang S,Deng T,Wu H,Chen F,Jin Y

更新日期：2006-05-01 00:00:00