Liposomes incorporating essential oil of Brazilian cherry (Eugenia uniflora L.): characterization of aqueous dispersions and lyophilized formulations.


:Multilamellar liposomes incorporating essential oil of Brazilian cherry (Eugenia uniflora L.) leaves were produced by dry film hydration. Gas chromatography demonstrated the compounds found in the essential oil were effectively incorporated in the aqueous dispersions of liposomes. Differential scanning calorimetry analyses revealed the incorporation of the essential oil did not cause phase separation in the membrane structure; the gel-liquid crystalline transition temperature (main transition) remained the same despite the higher heterogeneity indicated by the transition peak broadening. Different cryoprotectors (sucrose and trehalose) were added to the liposomal formulations to be tested in their ability to protect the liposomal structure during the lyophilization. The morphological aspect of the lyophilized powders analysed by scanning electron microscopy showed significant differences among the samples with and without cryoprotectors. Fourier-transform infrared spectroscopy indicated the cryoprotectors interacted effectively with the polar heads of phospholipids in the bilayer. In terms of water absorption, trehalose was identified as a much more effective protector agent against it than sucrose. The cryoprotectors showed different degrees of effectiveness of preservation of the liposomal structure when the rehydration assays of lyophilized liposomes were carried out, as particle size measurements indicated a moderate process of fusion when the formulations with sucrose were rehydrated.


J Microencapsul


Yoshida PA,Yokota D,Foglio MA,Rodrigues RA,Pinho SC




Has Abstract


2010-01-01 00:00:00












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    journal_title:Journal of microencapsulation

    pub_type: 杂志文章


    authors: Panda J,Satapathy BS,Mandal B,Sen R,Mukherjee B,Sarkar R,Tudu B

    更新日期:2021-01-01 00:00:00

  • Preparation of sub-100-nm beta-lactoglobulin (BLG) nanoparticles.

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    journal_title:Journal of microencapsulation

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    authors: Ko S,Gunasekaran S

    更新日期:2006-12-01 00:00:00

  • Preparation and characterization of calcium-shellac spheres as a carrier of carbamide peroxide.

    abstract::This paper describes a novel approach to prepare and characterize calcium-shellac spheres as a carrier of a tooth whitening agent carbamide peroxide. Calcium-shellac spheres were prepared using an extrusion technique based on dropping aqueous ammonium shellac solution into calcium chloride solution. The effects of for...

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    pub_type: 杂志文章


    authors: Xue J,Zhang Z

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  • Water-in-oil-in-water double emulsions loaded with chlorogenic acid: release mechanisms and oxidative stability.

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    journal_title:Journal of microencapsulation

    pub_type: 杂志文章


    authors: Dima C,Dima S

    更新日期:2018-09-01 00:00:00

  • 99mTc-labelled monodisperse latex particles coated with amino or carboxyl groups for studies of GI function.

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    journal_title:Journal of microencapsulation

    pub_type: 杂志文章


    authors: Ercan MT,Tuncel SA,Caner BE,Pişkin E

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    journal_title:Journal of microencapsulation

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    journal_title:Journal of microencapsulation

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    authors: Ming Y,Hu J,Xing J,Wu M,Qu J

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    pub_type: 杂志文章


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    pub_type: 杂志文章


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    pub_type: 杂志文章


    authors: Gaca S,Reichert S,Rödel C,Rödel F,Kreuter J

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    journal_title:Journal of microencapsulation

    pub_type: 杂志文章


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    pub_type: 杂志文章


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    pub_type: 杂志文章


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    pub_type: 杂志文章


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  • Controlled release effect of insecticide microcapsules and their results in common household insect pest control.

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    journal_title:Journal of microencapsulation

    pub_type: 杂志文章


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    journal_title:Journal of microencapsulation

    pub_type: 杂志文章


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    journal_title:Journal of microencapsulation

    pub_type: 杂志文章


    authors: Donbrow M,Hoffman A,Benita S

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    pub_type: 杂志文章


    authors: Hezaveh H,Muhamad II,Noshadi I,Shu Fen L,Ngadi N

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    authors: Yenice I,Caliş S,Atilla B,Kaş HS,Ozalp M,Ekizoğlu M,Bilgili H,Hincal AA

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    pub_type: 杂志文章


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