Abstract:
:Rosin was esterified with pentaerythritol and intermediate reaction products with different acid values were isolated. Microcapsules containing sulphadiazine were prepared by a solvent evaporation technique using these esters as wall materials. The microcapsules were evaluated for their size, drug content, and release characteristics in simulated gastric and intestinal fluids. The microcapsule size increased as the acid value of the ester decreased. The release of the drug was studied by using first-order, Higuchi and Hixon-Crowell cube root models. The release mechanism of the microcapsules is discussed.
journal_name
J Microencapsuljournal_title
Journal of microencapsulationauthors
Sheorey DS,Dorle AKdoi
10.3109/02652049409040434subject
Has Abstractpub_date
1994-01-01 00:00:00pages
11-7issue
1eissn
0265-2048issn
1464-5246journal_volume
11pub_type
杂志文章abstract::In this study, the anticancer activities of two siRNA carriers were compared using a human lung adenocarcinoma epithelial cell line (A549). Firstly, poly(styrene)-graft-poly(linoleic acid) (PS-g-PLina) and poly(styrene)-graft-poly(linoleic acid)-graft-poly(ethylene glycol) (PS-g-PLina-g-PEG) graft copolymers were synt...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.1080/02652048.2019.1665117
更新日期:2019-11-01 00:00:00
abstract::The body distribution of surfactant-coated and non-coated poly(methyl methacrylate) nanoparticles with a size of 131 +/- 30 nm after intravenous injection into rats was investigated. The coating materials were poloxamine 904, poloxamine 908, poloxamine 1508, poloxamer 338, and Brij 35. These materials were preselected...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.3109/02652049209021219
更新日期:1992-01-01 00:00:00
abstract:AIMS:This study was aimed to develop Isotretinoin (ITN) and α-tocopherol acetate (α-TA) loaded solid lipid nanoparticle topical gel for better skin sensitivity and potentiation of efficacy. METHODS:ITN and α-TA-loaded solid lipid nanoparticles (AE-SLN) were prepared by microemulsion method with glyceryl mono-stearate ...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.1080/02652048.2020.1823499
更新日期:2020-12-01 00:00:00
abstract::To overcome the recurrence problem in bladder tumours; nanoparticles with positive surface charge may improve interaction with biological membranes for intravesical administration. The aim of this study was to design, develop and evaluate (in vitro-in vivo) cationic nanoparticles based on chitosan, poly-L-lysine or po...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.3109/02652048.2012.668957
更新日期:2012-01-01 00:00:00
abstract::Enteric diastase spherules were prepared using cellulose acetate phthalate and eudragit RS-100 by emulsion solvent removal method. Factors that could affect the size shape and diastatic activity were studied. The studied factors include pH of aqueous media, temperature of dispersion media and concentration of surface ...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.3109/02652049109021868
更新日期:1991-10-01 00:00:00
abstract::Anal fissure is common and painful disease of anorectum. In this study, microparticles containing nifedipine and lidocaine HCl were prepared by spray drying and applied to bio-degradable and bio-stable tampons. Characterization of microparticles was determined by visual analyses, mass yield, particle size measurement,...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.1080/02652048.2017.1393113
更新日期:2017-12-01 00:00:00
abstract::The aim of this study was to investigate how glass transition temperature (Tg) influenced polymer microsphere formation and degradation of three chemically, similar novel salicylatebased poly(anhydride-esters): poly[1,6-bis(o-carboxyphenoxy)hexanoate] (CPH), Tg = 59 degrees C; poly[1,8-bis(o-carboxyphenoxy)octanoate] ...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.1080/02652040600776481
更新日期:2006-09-01 00:00:00
abstract:CONTEXT:Flavonoids show promising anticancer potential but it is limited due to poor solubility. OBJECTIVE:The present investigation was to prepare Chrysin-Phospholipid complex loaded solid lipid nanoparticles (Ch-PC-SLNs) for improving its encapsulation as compared to that of Chrysin loaded SLNs (Ch-SLNs) and evaluat...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.1080/02652048.2018.1559369
更新日期:2018-09-01 00:00:00
abstract::Since 1978 we have prepared microencapsulated insecticides by complex coacervation and interfacial polymerization for household insect pest control, fenthion being the main core element. A series of tests have been conducted against mosquitoes (Culex pipiens quinquefasciatus), cockroaches (Periplaneta americana) and b...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.3109/02652048409031543
更新日期:1984-10-01 00:00:00
abstract::The purpose of this study was to assess the antioxidant and anti-inflammatory potential of liposomal formulations enriched with Hypericum hookerianum (Hyp) aqueous extracts. Cotyledon segments derived from protocorms of H. hookerianum were cultured on Murashige and Skoog (MS) media supplemented with Kinetin (KN, 1 mgl...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.1080/02652048.2019.1631400
更新日期:2019-09-01 00:00:00
abstract::Latex particles coated with either amino or carboxyl groups were labelled with 99mTc. Two labelling methods were used: (1) direct labelling with tin reduction and (2) ligand exchange with tin pyrophosphate. Labelling efficiency and the radiochemical impurities were determined by thin-layer chromatography. Effect of [S...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.3109/02652049309015313
更新日期:1993-01-01 00:00:00
abstract::Different classes of excipients with potential for use in the design of novel pelletized formulations manufactured by extrusion-spheronization were examined using factorial experiments. Among the various silicates examined in a model mix with microcrystalline cellulose and lactose wetted with water, kaolin, talc and V...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.3109/02652049709006817
更新日期:1997-09-01 00:00:00
abstract::Optimum conditions for the preparation of non-magnetic and magnetic microspheres of albumin-globulin mix (alglomix) containing mefenamic acid have been standardized. The effect of various parameters has been investigated with regard to the appearance, yield, drug content and encapsulation efficiency. The physicochemic...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.3109/02652049109021856
更新日期:1991-01-01 00:00:00
abstract::To prepare the sustained release vitamin C carriers, vitamin C was successfully encapsulated in tripolyphosphate (TPP) cross-linked chitosan (TPP-chitosan) microspheres by the spray-drying method at different manufacturing conditions. Manufacturing parameters (inlet temperature, liquid flow rate, chitosan concentratio...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.1080/02652040500435436
更新日期:2006-02-01 00:00:00
abstract::The sorption of 5-fluorouracil from aqueous solutions onto poly(methyl methacrylate) was investigated. Linear sorption isotherms were obtained and no crystallinity of the nanoparticles after sorption was detectable by X-ray analysis indicating a partitioning of the drug into the polymer particles-forming a solid solut...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.3109/02652048609031560
更新日期:1986-04-01 00:00:00
abstract::Abietic acid was isolated from rosin N Grade (ISI) by a simple process and the product was further standardized. Sulphadiazine microcapsules were prepared by the solvent evaporation technique, using abietic acid as a wall-forming material. Discrete, spherical and free-flowing microcapsules were obtained by phase separ...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.3109/02652049209040481
更新日期:1992-10-01 00:00:00
abstract::Aims: The study was carried out to synthesise and characterise the chitosan-encapsulated genistein (CHI-En/Gen) and determine its anti-cancer and anti-angiogenic properties.Methods: The cytotoxic and anti-angiogenic activity of CHI-En/Gen was performed using MTT and chorioallantoic membrane assay. The molecular action...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.1080/02652048.2020.1740804
更新日期:2020-06-01 00:00:00
abstract::The diblock copolymers based on PBLG and PEO (GE) were synthesized and characterized. Nanoparticles showed spherical shape from the observations of TEM and approved core-shell structure. Drug contents were increased with use of higher initial drug concentration and higher Mw of GE. Nifedipine (NFD) release rate was sl...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.1080/02652040410001729241
更新日期:2004-06-01 00:00:00
abstract:CONTEXT:Quercetin (QUE) is a flavonoid with antioxidant/anti-inflammatory properties, poorly absorbed when orally administered. OBJECTIVES:To prepare chitosan/xanthan gum microparticles to increase QUE oral bioavailability and optimize its release in the colon. MATERIALS AND METHODS:Chitosan/xanthan gum hydrogel embe...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.3109/02652048.2014.913726
更新日期:2014-01-01 00:00:00
abstract::Microspheres, including microcapsules and cells or beads, are widely used to produce many functional products. Information about their mechanical properties is essential to understanding their performance during manufacturing, processing and end-use applications. The mechanical characterization of microspheres require...
journal_title:Journal of microencapsulation
pub_type: 杂志文章,评审
doi:10.3109/02652048.2011.646331
更新日期:2012-01-01 00:00:00
abstract:CONTEXT:Solid lipid nanoparticles (SLNs) can efficiently and efficaciously incorporate anti-cancer agents. OBJECTIVE:To prepare and characterise tamoxifen (TAM)-loaded SLNs. MATERIALS AND METHODS:Glyceryl monostearate, Tween-80, and trehalose were used in SLNs. SLNs were tested via dynamic light scattering (DLS), tra...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.3109/02652048.2014.898707
更新日期:2014-01-01 00:00:00
abstract::The size dependent and size independent contributions to the mechanical properties of poly(ethyleneglycol) microspheres with encapsulated air, made for medical ultrasound imaging, have been studied. A relation between the size of microspheres in a reference group and their acoustic attenuation efficacy was derived by ...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.1080/026520400288292
更新日期:2000-05-01 00:00:00
abstract::In ophthalmic drug delivery, a major problem is retaining an adequate concentration of a therapeutic agent in the pre-corneal area. Polycarboxylic acid carriers such as polyacrylic acid and polyitaconic acid in sub-colloidal, nanoparticulate hydrogel form have a strong potential for sustained release of a drug in ocul...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.1080/02652040400008515
更新日期:2004-12-01 00:00:00
abstract::The aim was to study the effect of the type of polymer solvent on characteristics of microspheres produced by spray drying. The water-soluble model protein, bovine serum albumin (BSA) was microencapsulated into biodegradable poly(D,L-lactic acid) using the following 10 different polymer solvents: acetaldehyde dimethyl...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.3109/02652049509051129
更新日期:1995-01-01 00:00:00
abstract::Microcapsules were prepared through an interfacial cross-linking process using terephthaloylchloride and applied to mixtures of a protein (human serum albumin or gelatin) and a polysaccharide. Their properties were compared with those of microcapsules prepared from the protein alone. Morphological characteristics of m...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.3109/02652049109069560
更新日期:1991-07-01 00:00:00
abstract::Vascular endothelial growth factor receptor (VEGFR) is over-expressed on a variety of tumour cells and tumour neovasculature, and so becomes well-documented target for cancer treatment. This study was designed to evaluate the cellular targeting and anti-tumor potency of VEGF-conjugated nanoparticles (VEGF-NPs). The po...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.3109/02652048.2015.1035683
更新日期:2015-01-01 00:00:00
abstract::Gelatin/gum arabic (GA) microcapsules were prepared by a convenient one step complex coacervation, in which TiO2 nanoparticles modified by stearic acid (SA) and homodispersed in tetrachloroethylene (TCE) were encapsulated. The modified TiO2 was characterized by Fourier transform infrared spectroscopy (FT-IR), dynamic ...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.1080/02652040802127806
更新日期:2009-02-01 00:00:00
abstract::Immunomagnetic systems have been used for positive selection of a cell fraction from a mixture using appropriate surface markers with satisfactory results, as haematopoietic CD34+ cells. This work reports on the development of poly(ethylene glycol)-grafted (PEG) immunoliposomes loaded with citrate-magnetite stabilized...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.1080/026520401750038593
更新日期:2001-01-01 00:00:00
abstract::The present study describes the development of a new cyclosporine formulation based on polycaprolactone (PCL) microspheres (MS) prepared by the solvent evaporation method. Ternary phase diagrams were used to identify the domains where MS were formed. The application of central composite designs established the influen...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.1080/02652040110055270
更新日期:2002-01-01 00:00:00
abstract::Ibuprofen-loaded polystyrene microparticles were prepared by the emulsion-solvent evaporation process from an aqueous system. The effects of different parameters on the drug content and on the release of the drug from the microparticles were investigated. The drug content, in all the formulations, was less than the th...
journal_title:Journal of microencapsulation
pub_type: 杂志文章
doi:10.1080/026520400288553
更新日期:2000-01-01 00:00:00