Liposomes as cyclosporin A carriers: positively charged lecithin-cholesterol liposomes associated with cyclosporin A do not inhibit biosynthesis of mitochondrial polyglycerophosphatides and microsomal phosphatidylinositol.

abstract：:Atomic force microscopy (AFM) is recognized a suitable and powerful technique for surface and morphological analysis. Even if until now this technique has not been frequently used in the pharmaceutical field, it can contribute to an accurate morphologic characterization of microspheres and nanospheres. In this work, a...

journal_title：Journal of microencapsulation

authors： Dorati R,Patrini M,Perugini P,Pavanetto F,Stella A,Modena T,Genta I,Conti B

更新日期：2006-03-01 00:00:00

abstract：:Monodisperse Ca-alginate microspheres were prepared using the membrane emulsification method. Three ionic types of drugs (anionic, cationic and non-ionic) were incorporated into the microspheres, and the effects of sodium alginate concentration and the pressure applied during the dispersing process on the properties o...

journal_title：Journal of microencapsulation

authors： You JO,Park SB,Park HY,Haam S,Chung CH,Kim WS

更新日期：2001-07-01 00:00:00

abstract：:This work aimed to investigate the potential effect of cyclodextrin encapsulation on intrinsic ability of daidzein (DAD) and genistein (GEN) to inhibit the glycosaminoglycan (GAG) synthesis in fibroblasts originating from patients with mucopolysaccharidosis (MPS), type II and III. DAD or GEN encapsulation with either ...

journal_title：Journal of microencapsulation

authors： Fumić B,Jablan J,Cinčić D,Zovko Končić M,Jug M

更新日期：2018-01-01 00:00:00

abstract：:The factors influencing the encapsulation of azathioprine (AZA) into liposomes were investigated to find out the conditions for its optimal entrapment. Similar studies for comparison were also carried out on 6-mercaptopurine (6-MP), of which AZA is a prodrug. AZA and also 6-MP show higher encapsulation efficiencies in...

journal_title：Journal of microencapsulation

authors： Gulati M,Grover M,Singh M,Singh S

更新日期：1998-07-01 00:00:00

abstract：:The entrapment of clofazimine (CLO) in a liposomal delivery system for topical application can protect it from absorption into the blood circulation and increase its residence time within the skin. This may reduce the very long mean period of leprosy treatment, as well as the side effects due to the long term administ...

journal_title：Journal of microencapsulation

authors： Patel VB,Misra AN

更新日期：1999-05-01 00:00:00

abstract：:This paper prepared novel biodegradable and pH-sensitive microgels based on Poly(epsilon-caprolactone)-Pluronic-Poly(epsilon-caprolactone)-dimethacrylate (PCFC-DMA), Poly(ethylene glycol) dimethacrylate (PEG-DMA) and methylacrylic acid (MAA) cross-linked with N,N'-methylenebisacrylamide (BIS), initiated by NaHSO(3), K...

journal_title：Journal of microencapsulation

authors： Xu X,Fu S,Wang K,Jia W,Guo G,Zheng X,Dong P,Guo Q,Qian Z

更新日期：2009-11-01 00:00:00

abstract：:The aim of this study was to formulate, characterise and evaluate the activity of amodiaquine microparticles against Leishmania donovani. Microparticles were formulated by encapsulating the drug in bovine serum albumin using the spray-dryer method. The microparticles were evaluated for size, zeta potential, drug conte...

journal_title：Journal of microencapsulation

authors： Nettey H,Allotey-Babington GL,Somuah I,Banga NB,Afrane B,Amponsah SK,Annor H,Darko H,Hanson K,Aidoo A,Broni MN,Sasu C,Nyarko A

更新日期：2017-02-01 00:00:00

abstract：:We demonstrate the microencapsulation of a double-base (DB) rocket propellant stabiliser, 2-nitrodiphenylamine (2-NDPA), that can potentially increase the shelf life of DB rocket propellants. Poly(lactide-co-glycolide) (PLG) microspheres loaded with 2-NDPA were prepared using the oil-in-water emulsion technique. The m...

journal_title：Journal of microencapsulation

authors： Shorty M,Singh S,Jebrail FF,Andrews MJ

更新日期：2012-01-01 00:00:00

abstract：:The soft microcapsules containing eucalyptus oil, ubiquinone and the fine water droplets could be prepared with interfacial dehydration reaction between hydroxy methyl cellulose and tannic acid using the water-in-oil-in-water type multiple (W/O)/W emulsion. The diameters of the microcapsules and the content and the mi...

journal_title：Journal of microencapsulation

authors： Taguchi Y,Suzuki T,Saito N,Yokoyama H,Tanaka M

更新日期：2017-12-01 00:00:00

abstract：:H-n.m.r. spectroscopy of small unilamellar phospholipid vesicles in the presence of the lanthanide probe ion Dy3+ has been used to study the permeability of these liposomes induced by the bile salts (glycocholate and glycodeoxycholate) and pancreatic phospholipase A2. A marked synergism is demonstrated in the combined...

journal_title：Journal of microencapsulation

authors： Hunt GR,Jones IC

更新日期：1984-04-01 00:00:00

abstract：:Bacampicillin hydrochloride has been microencapsulated to mask its very bitter taste. The objective of the study was to compare the in vitro release and bioavailability of bacampicillin hydrochloride from microcapsules coated with two principally different polymers: a water-insoluble polymer, ethylcellulose, and an ac...

journal_title：Journal of microencapsulation

authors： Sjöqvist R,Nyqvist H,Sjövall J,Westerlund D

更新日期：1985-04-01 00:00:00

abstract：:To prepare the sustained release vitamin C carriers, vitamin C was successfully encapsulated in tripolyphosphate (TPP) cross-linked chitosan (TPP-chitosan) microspheres by the spray-drying method at different manufacturing conditions. Manufacturing parameters (inlet temperature, liquid flow rate, chitosan concentratio...

journal_title：Journal of microencapsulation

authors： Desai KG,Park HJ

更新日期：2006-02-01 00:00:00

abstract：:The sorption of 5-fluorouracil from aqueous solutions onto poly(methyl methacrylate) was investigated. Linear sorption isotherms were obtained and no crystallinity of the nanoparticles after sorption was detectable by X-ray analysis indicating a partitioning of the drug into the polymer particles-forming a solid solut...

journal_title：Journal of microencapsulation

authors： Yalabik-Kas HS,Kreuter J,Hincal AA,Speiser PP

更新日期：1986-04-01 00:00:00

abstract：:An extrusion-based encapsulation process has been developed for making salt grain-sized iron premix for salt fortification. The first step of extrusion agglomeration process has been studied and reported previously. The focus of this study is on the optimisation of the colour-masking and polymer coating steps. Several...

journal_title：Journal of microencapsulation

authors： Yadava D,Olive Li Y,Diosady LL,Wesley AS

更新日期：2012-01-01 00:00:00

abstract：:The influence of drug particle size on the production of enteric beads by a polymer precipitation technique was investigated. Drug particle dimensions are known to play an important role in most microencapsulation techniques. Bead morphology was greatly influenced by drug particle size, and spherical shaped beads coul...

journal_title：Journal of microencapsulation

authors： Cerdeira AM,Gouveia LF,Goucha P,Almeida AJ

更新日期：2000-11-01 00:00:00

abstract：:In this study, recombinant human interleukin-2 (rhIL-2) containing poly(lactic-co-glycolic acid) (PLGA) microparticles were prepared for pulmonary administration by modified w/o/w double emulsion solvent extraction method and the effects of various formulation parameters on the physicochemical properties of the microp...

journal_title：Journal of microencapsulation

authors： Devrim B,Bozkir A,Canefe K

更新日期：2011-01-01 00:00:00

abstract：:Regular spherical microspheres of 220-260 microns average size have been prepared from vinylpyrrolidone/vinylacetate copolymer using a solvent evaporation method. Griseofulvin has been incorporated into these microspheres and its physical characterization has been carried out by differential scanning calorimetry (DSC)...

journal_title：Journal of microencapsulation

authors： Vojnovic D,Rubessa F,Bogataj M,Mrhar A

更新日期：1993-01-01 00:00:00

abstract：:Redox-responsive magnetic protein microcapsules with Fe3O4 magnetic nanoparticles (MNPs) encapsulated inside have been obtained using a facile, cost-effective and fast sonochemical method from hen egg white proteins. Such prepared redox-responsive magnetic hen egg white protein microcapsules (MHEWPMCs) could be easily...

journal_title：Journal of microencapsulation

authors： Zhong S,Cui X,Tian F

更新日期：2015-01-01 00:00:00

abstract：CONTEXT:Coated whey protein micro-beads may improve probiotic protection and provide delayed cell-release mechanisms. OBJECTIVE:Lactobacillus rhamnosus GG was encapsulated in whey protein micro-beads by droplet extrusion with coating via electrostatic deposition: primary-polysaccharide and secondary-whey protein. MAT...

journal_title：Journal of microencapsulation

authors： Doherty SB,Auty MA,Stanton C,Ross RP,Fitzgerald GF,Brodkorb A

更新日期：2012-01-01 00:00:00

abstract：:The objective of this study was to prepare floating theophylline microspheres with zero order release profiles for use as buoyant reservoirs with increased retention time in the stomach. The microspheres were prepared by a modified emulsion-solvent evaporation method using a polymer mixture of cellulose acetate butyra...

journal_title：Journal of microencapsulation

authors： Stithit S,Chen W,Price JC

更新日期：1998-11-01 00:00:00

abstract：:The aim of the present study is to construct a type of polyion complex micelles made of PF127-PEI copolymer and cholic acid (CA) and to evaluate the potential of this type of micelles as a targeted drug delivery system for paclitaxel (PTX). To further improve the targeting capability of micelles, folate was also incor...

journal_title：Journal of microencapsulation

authors： Li Y,Zhou Y,De B,Li L

更新日期：2014-01-01 00:00:00

abstract：:Chlorogenic acid (CA) is a natural compound used as an antioxidant in the preparation of food, drugs, and cosmetics. Due to their low stability and bioavailability, many researchers have studied the encapsulation of CA in various delivery colloidal systems. The aim of this study was to evaluate the stability of water-...

journal_title：Journal of microencapsulation

authors： Dima C,Dima S

更新日期：2018-09-01 00:00:00

abstract：:Anal fissure is common and painful disease of anorectum. In this study, microparticles containing nifedipine and lidocaine HCl were prepared by spray drying and applied to bio-degradable and bio-stable tampons. Characterization of microparticles was determined by visual analyses, mass yield, particle size measurement,...

journal_title：Journal of microencapsulation

authors： Sarıışık AM,Karavana SY,Türkoğlu GC,Rençber S,Önder T

更新日期：2017-12-01 00:00:00

abstract：:In ophthalmic drug delivery, a major problem is retaining an adequate concentration of a therapeutic agent in the pre-corneal area. Polycarboxylic acid carriers such as polyacrylic acid and polyitaconic acid in sub-colloidal, nanoparticulate hydrogel form have a strong potential for sustained release of a drug in ocul...

journal_title：Journal of microencapsulation

authors： De TK,Bergey EJ,Chung SJ,Rodman DJ,Bharali DJ,Prasad PN

更新日期：2004-12-01 00:00:00

abstract：:Vascular endothelial growth factor receptor (VEGFR) is over-expressed on a variety of tumour cells and tumour neovasculature, and so becomes well-documented target for cancer treatment. This study was designed to evaluate the cellular targeting and anti-tumor potency of VEGF-conjugated nanoparticles (VEGF-NPs). The po...

journal_title：Journal of microencapsulation

authors： Shi Y,Zhou M,Zhang J,Lu W

更新日期：2015-01-01 00:00:00

abstract：:N-lauroyl chitosan (NLCS) conjugates with different degrees of substitution (DS) of lauroyl group were synthesized and used to prepare surface modified poly(lactic-co-glycolic) acid (NLCS-PLGA) nanoparticles via hydrophobic interaction and ionic bond force. NLCS-PLGA nanoparticles had spherical shape with shell-core s...

journal_title：Journal of microencapsulation

authors： Li J,Zhou P,Wang Y,Chen H,Zhang C,Li R,Yang X,Wang Y

更新日期：2014-01-01 00:00:00

abstract：:Nanoparticles prepared of human serum albumin (HSA) represent promising carriers for drug delivery. Desolvating procedure is a common method to obtain protein-based particles. However process parameters have a great influence on size, size distribution and particle yield of the resulting formulation. Therefore, it is ...

journal_title：Journal of microencapsulation

authors： Storp Bv,Engel A,Boeker A,Ploeger M,Langer K

更新日期：2012-01-01 00:00:00

abstract：:Low molecular weight heparin (LMWH)-loaded flexible liposomes (flexosomes) were formulated for transdermal delivery, and their physicochemical and pharmacokinetic parameters were compared with LMWH-loaded ethosomes. Flexosomes had similar particle size compared with ethosomes, but their deformability was higher than t...

journal_title：Journal of microencapsulation

authors： Song YK,Hyun SY,Kim HT,Kim CK,Oh JM

更新日期：2011-01-01 00:00:00

abstract：PURPOSE:To develop a stable and reproducible modified release pellet formulation containing ibuprofen. METHODS:Using extrusion-spheronization technology to produce pellets. RESULTS:The percentage yield, size distribution and overall pellet shape within the desired size range of 1000-1400 microm was found to be depend...

journal_title：Journal of microencapsulation

authors： Lutchman D,Dangor CM,Perumal D

更新日期：2005-09-01 00:00:00

abstract：:Acidic and basic nonsteroidal anti-inflammatory drugs were encapsulated with cellulose derivatives having different functional groups, acidic (carboxymethyl cellulose), basic (chitosan), and neutral (hydroxypropylmethyl cellulose). The properties of the microcapsules were studied and the interaction of the drugs with ...

journal_title：Journal of microencapsulation

authors： Meshali MM,el-Dien EZ,Omar SA,Luzzi LA

更新日期：1989-07-01 00:00:00