Abstract：
OBJECTIVE:The study investigated the feasibility and potential outcome measures during acute hyperoxia in type 2 diabetes patients (DM2). METHODS:Eleven DM2 patients (7 men and 4 women) were included in the study. The patients cycled (30 min at 20% Wmax) whilst breathing three different supplemental oxygen flows (SOF, 5, 10, 15 L min(-1)). During hyperoxic exercise, arterial blood gases and intra-arterial blood pressure measurements were obtained. RESULTS:Arterial pO2 levels increased significantly (ANOVA, p < 0.05) with SOF: 13.9 ± 1.2 (0 L min(-1)); 18.5 ± 1.5 (5 L min(-1)); 21.7 ± 1.7 (10 L min(-1)); 24.0 ± 2.3 (15 L min(-1)). Heart rate (HR) and pH increased significantly after terminating administration of hyperoxic air. CONCLUSIONS:An SOF of 15 L min(-1) appears to be more effective than 5 or 10 L min(-1). Moreover, HR, blood pressure, blood lactate and pH are not recommended as primary outcome measures.
journal_name
Eur J Med Resjournal_title
European journal of medical researchauthors
Rozenberg R,Mankowski RT,van Loon LJ,Langendonk JG,Sijbrands EJ,van den Meiracker AH,Stam HJ,Praet SFdoi
10.1186/s40001-015-0194-5subject
Has Abstractpub_date
2016-01-08 00:00:00pages
1eissn
0949-2321issn
2047-783Xpii
10.1186/s40001-015-0194-5journal_volume
21pub_type
杂志文章abstract：BACKGROUND:Radial artery access is the primary approach for coronary interventions due to higher safety profile in comparison to femoral access. Radial artery occlusion (RAO) is the main complication of transradial catheterization that can lead to severe symptoms and a permanent artery occlusion. The incidence of RAO a...
journal_title：European journal of medical research
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更新日期：2018-05-22 00:00:00
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journal_title：European journal of medical research
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journal_title：European journal of medical research
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journal_title：European journal of medical research
pub_type： 临床试验,杂志文章,随机对照试验
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更新日期：2007-05-29 00:00:00
abstract：:The European Directive 98/79/EC on in vitro diagnostic medical devices (IVD) stipulates the marketing and post market surveillance of IVD in the European Economic Area. In cases of issues and field corrective actions, the manufacturers have to inform the responsible Competent Authorities (CA). In Germany, the Federal ...
journal_title：European journal of medical research
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journal_title：European journal of medical research
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journal_title：European journal of medical research
pub_type： 杂志文章
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journal_title：European journal of medical research
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journal_title：European journal of medical research
pub_type： 杂志文章
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journal_title：European journal of medical research
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journal_title：European journal of medical research
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更新日期：1999-02-25 00:00:00
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journal_title：European journal of medical research
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journal_title：European journal of medical research
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journal_title：European journal of medical research
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journal_title：European journal of medical research
pub_type： 杂志文章,评审
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更新日期：2004-05-28 00:00:00
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journal_title：European journal of medical research
pub_type： 杂志文章,评审
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更新日期：2004-03-30 00:00:00
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journal_title：European journal of medical research
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journal_title：European journal of medical research
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更新日期：2004-12-22 00:00:00
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journal_title：European journal of medical research
pub_type： 杂志文章
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更新日期：1997-07-28 00:00:00
