Abstract:
:As it has been reported that basic fibroblast growth factor (bFGF) is a circulating peptide and bFGF gene expression is increased after myocardial ischemia, this study was designed to investigate the serum levels of bFGF in patients with acute myocardial infarction (AMI). Using a bFGF enzyme-linked immunoassay, bFGF levels were determined in venous blood of 15 patients with AMI on admission, at 10 days, and 30 days after infarction, and of 15 age-matched healthy volunteers who were used as controls. bFGF serum levels on admission were similar to normal values (7.48 +/- 2.3 vs 8.14 +/- 2.9 pg/ml). However, they significantly increased (16.82 +/- 3.4 pg/ml; p <0.05) 10 days after the onset of AMI, and at 30 days they returned to baseline (7.07 +/- 2.9 pg/ml). The increased bFGF levels at the second week post AMI suggest that bFGF plays an important role in mediating the development of coronary collateral circulation after myocardial ischemia in humans.
journal_name
Eur J Med Resjournal_title
European journal of medical researchauthors
Cuevas P,Barrios V,Giménez-Gallego G,Martinez-Coso V,Cuevas B,Benavides J,Garcia-Segovia J,Asin-Cardiel Esubject
Has Abstractpub_date
1997-07-28 00:00:00pages
282-4issue
7eissn
0949-2321issn
2047-783Xjournal_volume
2pub_type
杂志文章abstract:OBJECTIVES:To report an extremely rare case of ovarian borderline mucinous cystic tumor accompanied by low-grade endometrial stromal sarcoma (LGESS) with myxoid change. CASE PRESENTATION:A 42-year-old woman complained of lower left abdominal fullness. Her serum carcinoembryonic antigen, cancer antigen (CA) 125, and CA...
journal_title:European journal of medical research
pub_type: 杂志文章,评审
doi:10.1186/s40001-017-0295-4
更新日期:2017-12-02 00:00:00
abstract::A serological diagnosis (ELISA test) was carried out of infections by Helicobacter pylori in 1200 young males (recruits in the Polish Army) and the influence of selected epidemiologico-clinical factors (civil status, place of residence, profession, economical conditions, tobacco smoking, consumption of alcohol, diseas...
journal_title:European journal of medical research
pub_type: 杂志文章
doi:
更新日期:1997-08-28 00:00:00
abstract:OBJECTIVE:We intended to determine the reliability of a brief life satisfaction scale in a sample of patients with chronic diseases, and to analyze its external validity. METHODS:Reliability and factor analysis of the 8-item "Brief Multidimensional Life Satisfaction Scale" (BMLSS) were performed according to standard ...
journal_title:European journal of medical research
pub_type: 杂志文章,多中心研究
doi:10.1186/2047-783x-14-4-171
更新日期:2009-04-16 00:00:00
abstract:INTRODUCTION:Recombinant human growth hormone (r-hGH) has demonstrated efficacy in treating HIV-associated wasting (HAW), however, HAW has become less prominent since the introduction of highly active antiretroviral therapy (HAART). Recent studies suggest that patients receiving HAART may still experience HAW. We inves...
journal_title:European journal of medical research
pub_type: 临床试验,杂志文章,多中心研究
doi:
更新日期:2002-03-28 00:00:00
abstract::Infant formulas containing medium chain triglycerides (MTC) have been used for the nutritional management of infants with fat malabsorption. The optimal proportion of MTC in the formula remains to be determined. Three infant formulas with varying proportion of MTC in the fat blend were studied in children with cystic ...
journal_title:European journal of medical research
pub_type: 杂志文章,评审
doi:
更新日期:1997-02-21 00:00:00
abstract:BACKGROUND:The concept of total mesorectal excision has revolutionised rectal cancer surgery. TME reduces the rate of local recurrence and tumour associated mortality. However, in clinical trials only 50% of the removed rectal tumours have an optimal TME quality. PATIENTS:During a period of 36 months we performed 103 ...
journal_title:European journal of medical research
pub_type: 杂志文章
doi:10.1186/2047-783x-15-7-292
更新日期:2010-01-01 00:00:00
abstract::A 62-year-old white male presented with facial erythema and jugular vein distension in upright position which progressed to cyanosis and facial edema while keeping both arms elevated (Pemberton sign). A CT scan revealed a large substernal goiter as the cause of superior vena cava syndrome. Symptoms and signs disappear...
journal_title:European journal of medical research
pub_type: 杂志文章
doi:
更新日期:1997-11-28 00:00:00
abstract:OBJECTIVE:Evaluating the effects of prophylactic administration of IgM-enriched immunoglobulins (IVIG) on immunological- and clinical parameters in cardiac surgical patients. PATIENTS AND METHODS:41 patients were randomized to receive either an IgM-enriched immunoglobulin (Pentaglobin(R)) preparation (1,300 ml immunog...
journal_title:European journal of medical research
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:2002-12-17 00:00:00
abstract::Nocturnal cardiac arrhythmias (NCA) were analyzed in patients with sleep apnea/hypopnea syndrome (SAHS) and controls. Occurrence and severity of NCA were compared in 33 SAHS patients and 16 control subjects, matched for cardiovascular risk factors. Continuous overnight polysomnography provided ECG, respiratory and sle...
journal_title:European journal of medical research
pub_type: 杂志文章
doi:10.1186/2047-783x-15-s2-193
更新日期:2010-11-04 00:00:00
abstract:BACKGROUND:International guidelines for the treatment of HIV-1 infected children recommend efavirenz plus nucleoside reverse transcriptase inhibitor combination therapy for first line therapy. Until now little is known about the steady state pharmacokinetics of efavirenz in children. METHODS:11 HIV-1 infected children...
journal_title:European journal of medical research
pub_type: 杂志文章
doi:
更新日期:2006-09-29 00:00:00
abstract:OBJECTIVE:Oxygen therapy is used for the treatment of various diseases, but prolonged exposure to high concentrations of O(2) is also associated with formation of free radicals and oxidative damage. METHODS:In the present study we compared alpha-ketoglutarate dehydrogenase (KGDH) activity and mitochondrial oxidative d...
journal_title:European journal of medical research
pub_type: 杂志文章
doi:10.1186/2047-783x-14-s4-116
更新日期:2009-12-07 00:00:00
abstract::Progressive infantile spastic tetraparesis spans a wide spectrum of partially rare differential diagnoses. Based on a clinical example the differential diagnostic thoughts are discussed in detail. Though juvenile motor neuron disease is a rare entity, it has to be kept in mind for differential diagnostics in cases of ...
journal_title:European journal of medical research
pub_type: 杂志文章
doi:
更新日期:2008-10-27 00:00:00
abstract:BACKGROUND:A great variety of dental materials are now available for use in restorative treatments. Much attention has been devoted to physical and chemical properties, but the biological effects of these materials have been less frequently studied. AIM:The aim of this study is to test the influence of resin based res...
journal_title:European journal of medical research
pub_type: 杂志文章
doi:
更新日期:2001-10-29 00:00:00
abstract:BACKGROUND:The literature did not show clearly if a correlation between trunk and facial asymmetry exists. The aim of this study was to verify the association between trunk and facial asymmetries, and trunk and facial sagittal configuration in adolescents. METHODS:This is a cross-sectional screening study. It was carr...
journal_title:European journal of medical research
pub_type: 杂志文章
doi:10.1186/s40001-017-0280-y
更新日期:2017-09-29 00:00:00
abstract::The immunological environment of leukemic blasts in the bone marrow might play a decisive role in determining an individual's risk for relapse. In order to identify potential predictors of relapse and to elucidate the mechanisms of immune control of leukemic blasts we examined the expression of cytokines, costimulator...
journal_title:European journal of medical research
pub_type: 杂志文章
doi:
更新日期:2006-03-27 00:00:00
abstract::More than one quarter of total daily calories are normally provided by fatty acids which contain at least one double bond. The usual configuration of these double bonds is the cis configuration. Trans fatty acids (TFA) are formed in technological and microbiological processes by isomerization of cis double bonds to tr...
journal_title:European journal of medical research
pub_type: 杂志文章,评审
doi:
更新日期:2003-08-20 00:00:00
abstract::The history and todays knowledge on the pathogenesis of arteriosclerosis emphasizing the importance of cholesterol concentration in plasma for the development of atherosclerosis is summarized. For proving the lipid hypothesis careful patient observation and new findings of molecular biology have added important inform...
journal_title:European journal of medical research
pub_type: 杂志文章,评审
doi:
更新日期:1997-06-16 00:00:00
abstract:BACKGROUND:Dopamine agonists (DA) are the first-choice drug for treatment of the early stage of Parkinson's disease (PD) in subjects younger than 70 years. Recently, a number of third generation DA have been marketed, including transdermal patch of rotigotine and extended release oral formulation of ropinirole and pram...
journal_title:European journal of medical research
pub_type: 杂志文章
doi:10.1186/2047-783X-18-60
更新日期:2013-12-21 00:00:00
abstract::Five patients with non-cytotoxic drug-induced agranulocytosis were treated with recombinant human granulocyte-colony-stimulating factor (rh-G-CSF). The drugs involved were dipyrone, captopril, clozapine and carbimazole. Bone marrow examination revealed a depleted granulopoiesis with normal erythro- and megakaryocytopo...
journal_title:European journal of medical research
pub_type: 杂志文章
doi:
更新日期:1995-12-18 00:00:00
abstract:BACKGROUND:During the last few years a number of previously undescribed viruses, including human metapneumovirus, coronaviruses SARS, NL63 and HKU1, and bocavirus, were identified in nasopharyngeal samples from patients with signs of respiratory infections. These viruses may cause mild to life-threatening infections. ...
journal_title:European journal of medical research
pub_type: 杂志文章
doi:
更新日期:2007-03-26 00:00:00
abstract::Infectious diseases remain a major cause of morbidity and mortality in the year 2000. 17 million deaths per year or roughly a third of all deaths are caused by infections. Infectious diseases also pose a serious economic threat. While many well-established pathogens have not been contained several new infectious agent...
journal_title:European journal of medical research
pub_type: 总体
doi:
更新日期:2000-11-30 00:00:00
abstract::A 65-year old woman with known history of reactive depression and failed suicide attempts ingested 7 mg digitoxin at 09.00 h. After vomiting 4 hours later, she reported the drug intake to her husband who thereupon summoned a physician. Arriving at 16.00 h, the physician was informed about the suicide attempt, but fail...
journal_title:European journal of medical research
pub_type: 杂志文章
doi:
更新日期:1996-11-25 00:00:00
abstract::Determination of fecal excretion of the serum proteinase inhibitor alpha(1)-antitrypsin (AAT) is established for quantification of intestinal protein loss. It was demonstrated to be increased both in quiescent and in active inflammatory bowel diseases (IBD, Crohn's disease and ulcerative colitis). The (patho)physiolog...
journal_title:European journal of medical research
pub_type: 杂志文章,评审
doi:
更新日期:1998-02-21 00:00:00
abstract::Possible effects of electromagnetic fields on human brain activity were studied. In a single-blind, cross-over-designed and placebo-controlled study 36 volunteers were exposed firstly to an electromagnetic field originating form a MediLine "MEGA-WAVE 150/1" therapy instrument and secondly to a field originating from a...
journal_title:European journal of medical research
pub_type: 临床试验,杂志文章
doi:
更新日期:1995-10-16 00:00:00
abstract:OBJECTIVES:The present study was carried out to assess compliance rates with annual colorectal cancer screening for fecal occult blood, and to identify the subjects with higher priority in health education to increase screen compliance. DESIGN AND SETTING:A screening program for colorectal cancer was conducted between...
journal_title:European journal of medical research
pub_type: 杂志文章
doi:
更新日期:1998-07-20 00:00:00
abstract:AIM:Antiseptics are commonly used in clinical practice to disinfect tissue and to avoid infections. However, topical antiseptics are assumed to have an influence on skin microcirculation, per se. Thus, the aim of the study was to analyse the influence of topically applied antiseptics on the microcirculation of intact s...
journal_title:European journal of medical research
pub_type: 杂志文章
doi:
更新日期:2004-09-29 00:00:00
abstract::Previous studies on Langerhans'-cell histiocytosis (LCH) were mostly retrospective and patients had been recruited over a long time period. The aim of the present study was to establish data on the clinical presentation, diagnosis and treatment of currently affected patients. Data on the clinical history, diagnostic w...
journal_title:European journal of medical research
pub_type: 杂志文章
doi:
更新日期:2004-11-29 00:00:00
abstract:BACKGROUND:Focal colorectal uptake in (18)FDG-PET/CT may be associated with a malignancy and can be quantified. This provides the basis for an automatic trigger threshold above which cases are flagged for colonoscopic evaluation and below which for individual assessment. PURPOSE:To determine the lowest maximum standar...
journal_title:European journal of medical research
pub_type: 杂志文章
doi:10.1186/s40001-016-0195-z
更新日期:2016-01-09 00:00:00
abstract:BACKGROUND:Ceftriaxone is commonly used as an alternative antibiotic drug in treating syphilis but clinical data on its efficacy are limited. OBJECTIVE:To evaluate the response of HIV-infected patients with active syphilis to treatment with penicillin or ceftriaxone. - METHODS:A retrospective study involving 24 conse...
journal_title:European journal of medical research
pub_type: 杂志文章
doi:10.1186/2047-783x-16-2-47
更新日期:2011-02-24 00:00:00
abstract::A fifty-year-old female presented with a one month history of progressive dyspnea, productive cough, pain of elbows and knees, and 40°C fever despite antibiotic treatment. She has been diagnosed of bronchial asthma over 25 years before admission and oral and depot glucocorticosteroids as a long-term therapy was applie...
journal_title:European journal of medical research
pub_type: 杂志文章
doi:10.1186/2047-783x-15-s2-92
更新日期:2010-11-04 00:00:00