Abstract：
BACKGROUND:Ceftriaxone is commonly used as an alternative antibiotic drug in treating syphilis but clinical data on its efficacy are limited. OBJECTIVE:To evaluate the response of HIV-infected patients with active syphilis to treatment with penicillin or ceftriaxone. - METHODS:A retrospective study involving 24 consecutive patients with a positive Veneral Disease Research Laboratory test (VDRL) and at least one specific treponemal test. 12 patients were treated with different regimens of high-dose penicillin G for at least 2 weeks. Another 12 patients were treated with ceftriaxone 1-2g per day intravenously for 10-21 days. - RESULTS:After a median follow up of 18,3 months all patients of the penicillin-treated group and 11 of 12 ceftriaxone-treated patients showed a ≥ 4-fold decline in VDRL-titers; 91% of them already within 6 months after therapy. - CONCLUSION:Our serological data demonstrate a comparable efficacy of currently recommened penicillin and ceftriaxone treatment regimens for active syphilis in HIV-infected patients.
journal_name
Eur J Med Resjournal_title
European journal of medical researchauthors
Spornraft-Ragaller P,Abraham S,Lueck C,Meurer Mdoi
10.1186/2047-783x-16-2-47subject
Has Abstractpub_date
2011-02-24 00:00:00pages
47-51issue
2eissn
0949-2321issn
2047-783Xjournal_volume
16pub_type
杂志文章abstract：OBJECTIVE:The aim of this study was to evaluate the efficacy and safety of composite extracts in reducing weight, as the main outcome measure. Secondary measures of the study were body composition change. DESIGN:Randomised, double blind, placebo-controlled clinical trial. SETTING:Tertiary university clinic. SUBJECTS...
journal_title：European journal of medical research
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：2006-08-30 00:00:00
abstract：BACKGROUND:In intestinal epithelium, tyrosine kinase receptor Ephrin B3 (Eph B3) maintains the architecture of the crypt-villus axis by repulsive interaction with its ligand ephrin-B1. While loss of Eph B3 is linked to colorectal cancer initiation, overexpression of Eph B3 in cancer cell lines inhibits growth and induc...
journal_title：European journal of medical research
pub_type： 杂志文章
doi：10.1186/2047-783X-17-10
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abstract：:The influence of heparin on Polymorphonuclear (PMN s) leukocytes was investigated using a new whole-blood cytofluorometric method (patent granted for the test with the number P 4334935.8-41) with Candida albicans and Staphylococcus aureus as test microorganisms. After comparing the effect of equal volumes of two widel...
journal_title：European journal of medical research
pub_type： 杂志文章
doi：
更新日期：1997-12-31 00:00:00
abstract：OBJECTIVE:To compare two reduced dose indinavir (IDV) + ritonavir (RTV) combinations guided by therapeutic drug monitoring (TDM) in treatment-naive HIV1-infected patients. METHODS:HIV1-infected treatment naive patients were prospectively randomized to treatment with IDV 600 mg or 400 mg BID each in combination with RT...
journal_title：European journal of medical research
pub_type： 杂志文章,随机对照试验
doi：
更新日期：2007-07-26 00:00:00
abstract：BACKGROUND:The literature did not show clearly if a correlation between trunk and facial asymmetry exists. The aim of this study was to verify the association between trunk and facial asymmetries, and trunk and facial sagittal configuration in adolescents. METHODS:This is a cross-sectional screening study. It was carr...
journal_title：European journal of medical research
pub_type： 杂志文章
doi：10.1186/s40001-017-0280-y
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abstract：BACKGROUND:Focal colorectal uptake in (18)FDG-PET/CT may be associated with a malignancy and can be quantified. This provides the basis for an automatic trigger threshold above which cases are flagged for colonoscopic evaluation and below which for individual assessment. PURPOSE:To determine the lowest maximum standar...
journal_title：European journal of medical research
pub_type： 杂志文章
doi：10.1186/s40001-016-0195-z
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abstract：OBJECTIVE:To report on radiological and epidemiological characteristics of pulmonary disease in patients with HIV infection in times of highly active antiretroviral therapy (HAART). METHODS:Clinical data of 130 HIV infected adults with acute pulmonary symptoms were compared with findings in chest radiography (n = 130)...
journal_title：European journal of medical research
pub_type： 杂志文章
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journal_title：European journal of medical research
pub_type： 杂志文章,meta分析
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journal_title：European journal of medical research
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doi：10.1186/s40001-016-0236-7
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journal_title：European journal of medical research
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journal_title：European journal of medical research
pub_type： 临床试验,杂志文章
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更新日期：2002-07-24 00:00:00
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journal_title：European journal of medical research
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journal_title：European journal of medical research
pub_type： 杂志文章,多中心研究
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journal_title：European journal of medical research
pub_type： 杂志文章,评审
doi：
更新日期：1998-02-21 00:00:00
abstract：:The history and todays knowledge on the pathogenesis of arteriosclerosis emphasizing the importance of cholesterol concentration in plasma for the development of atherosclerosis is summarized. For proving the lipid hypothesis careful patient observation and new findings of molecular biology have added important inform...
journal_title：European journal of medical research
pub_type： 杂志文章,评审
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更新日期：1997-06-16 00:00:00
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journal_title：European journal of medical research
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doi：
更新日期：2002-01-29 00:00:00
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journal_title：European journal of medical research
pub_type： 杂志文章
doi：
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journal_title：European journal of medical research
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journal_title：European journal of medical research
pub_type： 杂志文章,评审
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journal_title：European journal of medical research
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journal_title：European journal of medical research
pub_type： 临床试验,杂志文章,多中心研究
doi：
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journal_title：European journal of medical research
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：2002-04-30 00:00:00
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journal_title：European journal of medical research
pub_type： 杂志文章
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journal_title：European journal of medical research
pub_type： 杂志文章,meta分析,收录出版
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journal_title：European journal of medical research
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doi：
更新日期：2004-09-29 00:00:00
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journal_title：European journal of medical research
pub_type： 杂志文章,评审
doi：
更新日期：2007-10-15 00:00:00
abstract：:Tooth-colored resin-based restoration materials have gained enormous significance in recent decades. Since the composites presently available still evidence various weaknesses, intensive research continues concerning them. In this study we tested the biocompatibility of six resin-based materials (Charisma, Solitaire, ...
journal_title：European journal of medical research
pub_type： 杂志文章
doi：
更新日期：1999-04-27 00:00:00
