Abstract：
:Photoplethysmography enables non-invasive investigation of the volume pulse in the microvasculature of patients. We previously have shown that time-discrete analysis enables identification of highly reproducible characteristics of the volume pulse in absolute values. The method would be of particular interest, if the perfusion of deeper tissue layers like the skeletal muscle can be assessed. The aim of the current study was to investigate the attenuation of the photoplethysmographic signal by different tissues and up to which depth of tissue a time-discrete analysis of the photoplethysmographic signal would be possible. For the recordings we used the time-discrete near-infra-red photoplethysmography (NIRP), a reflection photoplethysmograph measuring at wavelengths of 840 nm and 640 nm. In an in vitro circuit filled with bovine blood we generated a typical and exactly reproducible volume pulse. On a platform the NIRP sensor probe was placed above the artificial vessel and recordings of the volume pulse were obtained by varying the sensor-vessel-distance with increasing layers of water, blood-agar or bovine skeletal muscle tissue. - The amplitude of the NIR signal was attenuated to 50% by each layer of 2.01 mm of water, 1.42 mm of blood-agar and 1.05 mm of bovine skeletal muscle tissue. A time-discrete analysis could be performed up to a depth of 15 mm of water, 6 mm of blood-agar and 5 mm of bovine skeletal muscle tissue. - As the photoplethysmographic curve is strongly attenuated even by a few millimetres of water we suggest that the NIRP signal mirrors the perfusion of the superficial tissue layer and mainly originates from the subpapillary capacious plexus. - We conclude that with the equipment used in this study volume pulsations in deeper layers of tissue like skeletal musculature can not be assessed.
journal_name
Eur J Med Resjournal_title
European journal of medical researchauthors
Niklas M,Moser U,Buehrer A,Valentin R,Abicht J,Baschnegger H,Christ Fsubject
Has Abstractpub_date
1998-05-12 00:00:00pages
241-8issue
5eissn
0949-2321issn
2047-783Xjournal_volume
3pub_type
杂志文章abstract：:The purpose of the present study was to evaluate clinically the effect of an anaesthetic gel (lidocaine 20 mg/g as active agent) on pain sensitivity and early wound healing following nonsurgical periodontal therapy. A total of 40 patients with chronic periodontitis were enrolled in this randomized, split-mouth, double...
journal_title：European journal of medical research
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：2007-05-29 00:00:00
abstract：BACKGROUND:Drug-eluting stents (DES) compared to bare metal stents (BMS) have shown superior clinical performance, but are considered less suitable in complex cases. Most studies do not distinguish between DES and BMS with respect to their mechanical performance. The objective was to obtain mechanical parameters for di...
journal_title：European journal of medical research
pub_type： 杂志文章
doi：10.1186/s40001-017-0300-y
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journal_title：European journal of medical research
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abstract：:A 62-year-old white male presented with facial erythema and jugular vein distension in upright position which progressed to cyanosis and facial edema while keeping both arms elevated (Pemberton sign). A CT scan revealed a large substernal goiter as the cause of superior vena cava syndrome. Symptoms and signs disappear...
journal_title：European journal of medical research
pub_type： 杂志文章
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journal_title：European journal of medical research
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更新日期：2001-12-17 00:00:00
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journal_title：European journal of medical research
pub_type： 杂志文章
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更新日期：1999-09-09 00:00:00
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journal_title：European journal of medical research
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journal_title：European journal of medical research
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journal_title：European journal of medical research
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journal_title：European journal of medical research
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journal_title：European journal of medical research
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journal_title：European journal of medical research
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更新日期：2000-11-30 00:00:00
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journal_title：European journal of medical research
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journal_title：European journal of medical research
pub_type： 杂志文章,meta分析,收录出版
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journal_title：European journal of medical research
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更新日期：2004-09-29 00:00:00
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journal_title：European journal of medical research
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journal_title：European journal of medical research
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journal_title：European journal of medical research
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journal_title：European journal of medical research
pub_type： 杂志文章,评审
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更新日期：1997-02-21 00:00:00
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journal_title：European journal of medical research
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journal_title：European journal of medical research
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