Abstract：
BACKGROUND:Resternotomy in cardiac surgery is considered a risk factor for postoperative complications. Previous studies have demonstrated an ambiguous relationship between resternotomy and clinical outcomes. Registry data from a mixed population of durable circulatory support devices suggest that history of cardiac surgery is a risk factor for mortality. Our study investigates the prognostic significance of resternotomy in a homogenous cohort of left ventricular assist device (LVAD) recipients. METHODS:The study included adult patients receiving a continuous-flow LVAD at our institution during the period 2010-2016. Postoperative adverse events and length of stay were analyzed. Survival was assessed at 6 months and by the end of the study. Multivariate risk factor analysis was conducted for independent predictors of death. RESULTS:One hundred twelve patients, who received an intrapericardial LVAD (HVAD, HeartWare), were included in our analysis. Twenty-four patients (21.4%) had a history of previous sternotomy. These patients were older and non-eligible for bridging, and had more frequently coronary heart disease. Univariate analysis demonstrated no differences in the observed complications postoperatively. Survival was similar among groups. Destination therapy was the only predictor of mortality in our analysis (p = 0.02). CONCLUSIONS:Resternotomy was not associated with worse outcomes after LVAD implantation in our cohort.
journal_name
Eur J Med Resjournal_title
European journal of medical researchauthors
Papathanasiou M,Tsourelis L,Pizanis N,Koch A,Kamler M,Rassaf T,Luedike Pdoi
10.1186/s40001-017-0289-2subject
Has Abstractpub_date
2017-11-15 00:00:00pages
46issue
1eissn
0949-2321issn
2047-783Xpii
10.1186/s40001-017-0289-2journal_volume
22pub_type
杂志文章abstract：:Infectious diseases remain a major cause of morbidity and mortality in the year 2000. 17 million deaths per year or roughly a third of all deaths are caused by infections. Infectious diseases also pose a serious economic threat. While many well-established pathogens have not been contained several new infectious agent...
journal_title：European journal of medical research
pub_type： 总体
doi：
更新日期：2000-11-30 00:00:00
abstract：BACKGROUND:International guidelines for the treatment of HIV-1 infected children recommend efavirenz plus nucleoside reverse transcriptase inhibitor combination therapy for first line therapy. Until now little is known about the steady state pharmacokinetics of efavirenz in children. METHODS:11 HIV-1 infected children...
journal_title：European journal of medical research
pub_type： 杂志文章
doi：
更新日期：2006-09-29 00:00:00
abstract：:The immunological environment of leukemic blasts in the bone marrow might play a decisive role in determining an individual's risk for relapse. In order to identify potential predictors of relapse and to elucidate the mechanisms of immune control of leukemic blasts we examined the expression of cytokines, costimulator...
journal_title：European journal of medical research
pub_type： 杂志文章
doi：
更新日期：2006-03-27 00:00:00
abstract：OBJECTIVE:Most industrialized countries experienced a change in dietary habits within the last 10 years. Growing obesity may result in an increased incidence of metabolic diseases as well as in a higher caries frequency. METHODS:In an interdisciplinary study, 842 elementary school children (414 girls and 428 boys, age...
journal_title：European journal of medical research
pub_type： 杂志文章
doi：
更新日期：2004-08-31 00:00:00
abstract：BACKGROUND:It is hitherto still questionable which of the physical properties of the bile fluid influence the outcome of extracorporeal shock wave lithotripsy (ESWL). METHODS:In this study the influence of the density and viscosity of bile simulating fluid on ESWL was tested in vitro by applying CsCl solutions of dens...
journal_title：European journal of medical research
pub_type： 杂志文章
doi：
更新日期：1996-01-19 00:00:00
abstract：:The influence of heparin on Polymorphonuclear (PMN s) leukocytes was investigated using a new whole-blood cytofluorometric method (patent granted for the test with the number P 4334935.8-41) with Candida albicans and Staphylococcus aureus as test microorganisms. After comparing the effect of equal volumes of two widel...
journal_title：European journal of medical research
pub_type： 杂志文章
doi：
更新日期：1997-12-31 00:00:00
abstract：OBJECTIVES:To report an extremely rare case of ovarian borderline mucinous cystic tumor accompanied by low-grade endometrial stromal sarcoma (LGESS) with myxoid change. CASE PRESENTATION:A 42-year-old woman complained of lower left abdominal fullness. Her serum carcinoembryonic antigen, cancer antigen (CA) 125, and CA...
journal_title：European journal of medical research
pub_type： 杂志文章,评审
doi：10.1186/s40001-017-0295-4
更新日期：2017-12-02 00:00:00
abstract：BACKGROUND:Renal impairment is a common complication of multiple myeloma occurring in up to 50 % of patients at some stage in their disease. Due to occurrence of cast nephropathies we hypothesized circulatory dysregulation (vasoconstriction) in the kidneys with measurable elevation of the resistance index among these p...
journal_title：European journal of medical research
pub_type： 杂志文章
doi：10.1186/2047-783x-15-5-210
更新日期：2010-05-18 00:00:00
abstract：BACKGROUND:Electroacupuncture is well known for its advantageous neuroanalgesic and therapeutic effects on myocardial ischemia-reperfusion injury. The purpose of the present research was to verify whether electroacupuncture can alleviate bupivacaine-induced myocardial injury. METHODS:Specific pathogen-free Wistar rats...
journal_title：European journal of medical research
pub_type： 杂志文章
doi：10.1186/s40001-020-00431-4
更新日期：2020-08-01 00:00:00
abstract：:The Gasperini syndrome is a very rare brainstem disease characterized by the typical combination of ipsilateral lesions of the cranial nerves V-VII and dissociated contralateral hemihypesthesia, whereas both contralateral and ipsilateral hypacusis was described. Since the first description in 1912, only a few cases of...
journal_title：European journal of medical research
pub_type： 杂志文章
doi：10.1186/2047-783x-14-9-413
更新日期：2009-09-01 00:00:00
abstract：:The purpose of the present study was to evaluate clinically the effect of an anaesthetic gel (lidocaine 20 mg/g as active agent) on pain sensitivity and early wound healing following nonsurgical periodontal therapy. A total of 40 patients with chronic periodontitis were enrolled in this randomized, split-mouth, double...
journal_title：European journal of medical research
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：2007-05-29 00:00:00
abstract：OBJECTIVE:Due to the side effects of antiretroviral therapy and long term survival there is an increasing concern of an elevated rate of cardiovascular diseases in HIV-infected patients. The present study analysed the cardiovascular risk profile and the probability of cardiovascular events in HIV-infected patients, due...
journal_title：European journal of medical research
pub_type： 杂志文章
doi：
更新日期：2004-02-27 00:00:00
abstract：:Exposure to high concentrations of oxygen is known to induce changes in lung function through effects on several pulmonary cell types, including alveolar macrophages (AM). In this study, we studied the in vitro effects of hyperoxia on the release of proinflammatory cytokines and the expression of surface receptors in ...
journal_title：European journal of medical research
pub_type： 杂志文章
doi：
更新日期：1997-04-21 00:00:00
abstract：BACKGROUND:Congenital fibrosis of the extraocular muscles type 1 (CFEOM1) is a congenital, non-progressive autosomal-dominant disorder with bilateral oculomotor nerve palsy due to mutations in the kinesin motor protein gene KIF21A. - RESULTS:We present a 60-year old patient with CFEOM1 due to the common C2860T mutatio...
journal_title：European journal of medical research
pub_type： 杂志文章
doi：
更新日期：2005-08-17 00:00:00
abstract：INTRODUCTION:Carcinoma of the collecting ducts of Bellini of the kidney (CDC) is very rare but among the most aggressive urological entities. Standard therapy is not well defined with questionable efficacy. METHODS:We present two cases of male patients (49 and 66 years old) with pT3a pN2 CDC treated with a combination...
journal_title：European journal of medical research
pub_type： 杂志文章
doi：
更新日期：2008-11-24 00:00:00
abstract：BACKGROUND:Ceftriaxone is commonly used as an alternative antibiotic drug in treating syphilis but clinical data on its efficacy are limited. OBJECTIVE:To evaluate the response of HIV-infected patients with active syphilis to treatment with penicillin or ceftriaxone. - METHODS:A retrospective study involving 24 conse...
journal_title：European journal of medical research
pub_type： 杂志文章
doi：10.1186/2047-783x-16-2-47
更新日期：2011-02-24 00:00:00
abstract：:Coronary angiograms performed at the time of an acute coronary syndrome typically present vessel occlusions, ruptured plaques or thrombotic lesions that require reperfusion therapy. However, occasionally, no coronary artery stenoses are detected. Myocardial ischemia frequently causes left ventricular wall motion abnor...
journal_title：European journal of medical research
pub_type： 杂志文章
doi：
更新日期：2008-08-18 00:00:00
abstract：:A 70-year-old woman with a progressive dominant hemisphere syndrome but only mild hemiparesis and a normal brain scan (>3 hours from stroke onset) showed angiographic occlusion of the left anterior cerebral artery and the middle cerebral artery at its trifurcation with preservation of the rolandic artery. Intra-arteri...
journal_title：European journal of medical research
pub_type： 杂志文章
doi：
更新日期：2000-07-19 00:00:00
abstract：UNLABELLED:Prolonged immobilization of severely ill, bed-ridden patients results in formation of pressure ulcers following inappropriate tissue blood perfusion, and local activation of leukocyte - endothelial cell interactions (L/EC). Various treatment modalities were implemented to improve local microcirculation with ...
journal_title：European journal of medical research
pub_type： 杂志文章
doi：
更新日期：2001-04-20 00:00:00
abstract：:More than one quarter of total daily calories are normally provided by fatty acids which contain at least one double bond. The usual configuration of these double bonds is the cis configuration. Trans fatty acids (TFA) are formed in technological and microbiological processes by isomerization of cis double bonds to tr...
journal_title：European journal of medical research
pub_type： 杂志文章,评审
doi：
更新日期：2003-08-20 00:00:00
abstract：:The aim of the study was to investigate whether cholecystokinin, neurotensin, and cholinergic mechanisms act as mediators of bile salt-stimulated exocrine pancreatic secretion. Ten fasting healthy subjects provided with a double-lumen tube received 2, 4, and 6 g cattle bile and 200, 400, and 600 mg Na-taurodeoxycholat...
journal_title：European journal of medical research
pub_type： 杂志文章
doi：
更新日期：1997-01-01 00:00:00
abstract：BACKGROUND:Fingertip injuries treated with occlusive dressings (ODs) lead to nearly scar-free, functionally, and aesthetically pleasing results. We hypothesized that paracrine factors in the wound fluid (secretome) may influence migration and proliferation of mesenchymal stem cells (MSCs) and fibroblasts and modulate t...
journal_title：European journal of medical research
pub_type： 杂志文章
doi：10.1186/s40001-018-0357-2
更新日期：2018-12-26 00:00:00
abstract：OBJECTIVE:The study investigated the feasibility and potential outcome measures during acute hyperoxia in type 2 diabetes patients (DM2). METHODS:Eleven DM2 patients (7 men and 4 women) were included in the study. The patients cycled (30 min at 20% Wmax) whilst breathing three different supplemental oxygen flows (SOF,...
journal_title：European journal of medical research
pub_type： 杂志文章
doi：10.1186/s40001-015-0194-5
更新日期：2016-01-08 00:00:00
abstract：:Five patients with non-cytotoxic drug-induced agranulocytosis were treated with recombinant human granulocyte-colony-stimulating factor (rh-G-CSF). The drugs involved were dipyrone, captopril, clozapine and carbimazole. Bone marrow examination revealed a depleted granulopoiesis with normal erythro- and megakaryocytopo...
journal_title：European journal of medical research
pub_type： 杂志文章
doi：
更新日期：1995-12-18 00:00:00
abstract：:In the absence of thromboprophylaxis, venous thromboembolism (VTE) affects about 50 to 80% of the patients after total hip replacement (THR), total knee replacement (TKR), or hip fracture surgery. Since stratification of patients in those who will become symptomatic and those who will not, is not possible, primary hig...
journal_title：European journal of medical research
pub_type： 杂志文章,评审
doi：
更新日期：2004-03-30 00:00:00
abstract：BACKGROUND:Breast cancer risk prediction models are widely used in clinical settings. Although most of the well-known models were designed based on data collected from western population, yet they have been utilized for surveillance purposes in many limited-resource countries. Given the genetic variations in risk facto...
journal_title：European journal of medical research
pub_type： 杂志文章,多中心研究
doi：10.1186/s40001-017-0277-6
更新日期：2017-09-29 00:00:00
abstract：:The introduction of integrase inhibitors as a new drug class for treatment of HIV have added a very potent and extremely well tolerated new treatment option to the HIV-armentarium. Particularly in patients with previously developed drug resistance, the availability of new active drugs offers great hope. Moreover, the ...
journal_title：European journal of medical research
pub_type： 杂志文章,评审
doi：10.1186/2047-783x-14-s3-1
更新日期：2009-11-24 00:00:00
abstract：BACKGROUND:Patients with congenital absence of the portal vein (CAPV) often suffer from additional medical complications such as hepatic tumors and cardiac malformations. CASE PRESENTATION:Congenital absence of the portal vein (CAPV) is a rare malformation. We present a case of a 16-year-old Chinese girl with CAPV wit...
journal_title：European journal of medical research
pub_type： 杂志文章,评审
doi：10.1186/s40001-014-0063-7
更新日期：2014-11-26 00:00:00
abstract：:Long-term pneumotachographic measurements in newborns are hampered by the apparatus dead space, which can be functionally eliminated by a constant bias flow (flow-through technique). In a clinical study the influence of this bias flow was investigated. - In 80 infants (group 1:20 healthy controls, group 2: 30 infants ...
journal_title：European journal of medical research
pub_type： 杂志文章
doi：
更新日期：1999-01-26 00:00:00
abstract：:A 62-year-old white male presented with facial erythema and jugular vein distension in upright position which progressed to cyanosis and facial edema while keeping both arms elevated (Pemberton sign). A CT scan revealed a large substernal goiter as the cause of superior vena cava syndrome. Symptoms and signs disappear...
journal_title：European journal of medical research
pub_type： 杂志文章
doi：
更新日期：1997-11-28 00:00:00
