Abstract：
:Long-term pneumotachographic measurements in newborns are hampered by the apparatus dead space, which can be functionally eliminated by a constant bias flow (flow-through technique). In a clinical study the influence of this bias flow was investigated. - In 80 infants (group 1:20 healthy controls, group 2: 30 infants recovering from a pulmonary disease, group 3: 30 pulmonary ill infants) with a body weight 1060-9000g and an age 1-402d respiratory frequency (f) was measured pneumotachographically (PN) as well as with breathing belts (BB) in four periods: before any alteration (period 1, only BB), during the first calm interval after attaching the face mask, in which lung function tests are usually performed (period 2, PN and BB), in a defined steady state giving longer time for adaptation (period 3, PN and BB) and after removing of the mask (period 4, only BB). During periods 2 and 3 tidal breathing parameters were measured from the air flow signal. - In period 1 there were significant differences between the groups in f (1/min) (42.1 +/- 8.3, 44.2 +/- 9.3, 54.2 +/- 16.5, p <0.05) which also existed in periods 3 and 4, but not in period 2 (47.6 +/- 14.9, 44.8 +/- 16.3, 51.2 +/- 15.8). In periods 3 and 4 in all groups, f returned to the initial values. In contrast to group 3 we found significant differences in most of the tidal breathing parameters between periods 2 and 3 in group 1 and 2. - It was concluded that the bias flow has a negligible influence on tidal breathing measurements and allows a sufficient adaptation period necessary to recognise small deviations.
journal_name
Eur J Med Resjournal_title
European journal of medical researchauthors
Windstetter D,Foitzik B,Schmalisch G,Wauer Rsubject
Has Abstractpub_date
1999-01-26 00:00:00pages
15-22issue
1eissn
0949-2321issn
2047-783Xjournal_volume
4pub_type
杂志文章abstract：OBJECTIVE:Identification of specific origin of lipid accumulation in the liver of patients with non-alcoholic fatty liver disease (NAFLD) is the most important step in preventing this condition. Because liver steatosis, in the obese patients without any systemic disease, can be graded easily by ultrasonography (US), we...
journal_title：European journal of medical research
pub_type： 杂志文章
doi：
更新日期：2007-02-26 00:00:00
abstract：:Pentalogy of Fallot is a rare cyanotic congenital heart disease characterized by biventricular origin of the aorta above a large ventricular septal defect, obstruction of the pulmonary outflow, right ventricular hypertrophy (tetralogy of Fallot), and an atrial septal defect. Mortality due to syncope, arrhythmia or con...
journal_title：European journal of medical research
pub_type： 杂志文章
doi：
更新日期：2001-06-28 00:00:00
abstract：BACKGROUND:In pursuit of improvement in cardiopulmonary resuscitation (CPR), new technologies for the measurement and assessment of CPR quality are implemented. In our study, we assessed the kinematics of the rescuer during continuous chest compression (CCC-CPR). The proper performance of the procedure is a survival pr...
journal_title：European journal of medical research
pub_type： 杂志文章
doi：10.1186/s40001-019-0369-6
更新日期：2019-02-08 00:00:00
abstract：:Targeted intrapulmonary delivery of drugs may reduce systemic toxicity, improve treatment efficacy, but inhaled drugs may also interfere with pulmonary surfactant function. We hypothesized that the lipophilic drug amphotericin B used to treat or prevent pulmonary infections with aspergillus species, might destroy surf...
journal_title：European journal of medical research
pub_type： 杂志文章
doi：
更新日期：1998-08-18 00:00:00
abstract：BACKGROUND:Burkholderia cepacia strains have been known to possess the capability to cause serious infections especially in neonatal intensive care units (NICUs), and their multi-drug resistances become a severe threat in hospital settings. The aim of this investigation was to evaluate the B. cepacia complex infections...
journal_title：European journal of medical research
pub_type： 杂志文章
doi：10.1186/2047-783x-16-12-537
更新日期：2011-12-02 00:00:00
abstract：BACKGROUND:Coronavirus is challenging the global health care system from time to time. The pregnant state, with alterations in hormone levels and decreased lung volumes due to a gravid uterus and slightly immunocompromised state may predispose patients to a more rapidly deteriorating clinical course and can get a great...
journal_title：European journal of medical research
pub_type： 杂志文章,meta分析
doi：10.1186/s40001-020-00439-w
更新日期：2020-09-04 00:00:00
abstract：:More than one quarter of total daily calories are normally provided by fatty acids which contain at least one double bond. The usual configuration of these double bonds is the cis configuration. Trans fatty acids (TFA) are formed in technological and microbiological processes by isomerization of cis double bonds to tr...
journal_title：European journal of medical research
pub_type： 杂志文章,评审
doi：
更新日期：2003-08-20 00:00:00
abstract：:Possible effects of electromagnetic fields on human brain activity were studied. In a single-blind, cross-over-designed and placebo-controlled study 36 volunteers were exposed firstly to an electromagnetic field originating form a MediLine "MEGA-WAVE 150/1" therapy instrument and secondly to a field originating from a...
journal_title：European journal of medical research
pub_type： 临床试验,杂志文章
doi：
更新日期：1995-10-16 00:00:00
abstract：BACKGROUND:Increasing rates of prosthetic joint infection (PJI) have presented challenges for general practitioners, orthopedic surgeons and the health care system in the recent years. The diagnosis of PJI is complex; multiple diagnostic tools are used in the attempt to correctly diagnose PJI. Evidence-based algorithms...
journal_title：European journal of medical research
pub_type： 杂志文章,meta分析
doi：10.1186/s40001-017-0245-1
更新日期：2017-03-09 00:00:00
abstract：BACKGROUND:Systemic treatment of head and neck squamous cell carcinoma (HNSCC) includes a variety of antineoplastic drugs. However, drug-resistance interferes with the effectiveness of chemotherapy. Preclinical testing models are needed in order to develop approaches to overcome chemoresistance. - METHODS:Ten human ce...
journal_title：European journal of medical research
pub_type： 杂志文章
doi：10.1186/2047-783x-15-8-337
更新日期：2010-08-20 00:00:00
abstract：OBJECTIVE:The study investigated the feasibility and potential outcome measures during acute hyperoxia in type 2 diabetes patients (DM2). METHODS:Eleven DM2 patients (7 men and 4 women) were included in the study. The patients cycled (30 min at 20% Wmax) whilst breathing three different supplemental oxygen flows (SOF,...
journal_title：European journal of medical research
pub_type： 杂志文章
doi：10.1186/s40001-015-0194-5
更新日期：2016-01-08 00:00:00
abstract：:Oxytocin is one of the most potent uterotonic agents and is known to fluctuate throughout the menstrual cycle, showing an increase during sexual stimulation and arousal, with a peak during orgasm in women. To date, limited data are available on the effects of oxytocin on the regulation of uterine contractility and tra...
journal_title：European journal of medical research
pub_type： 杂志文章
doi：
更新日期：2006-04-28 00:00:00
abstract：BACKGROUND:During the last few years a number of previously undescribed viruses, including human metapneumovirus, coronaviruses SARS, NL63 and HKU1, and bocavirus, were identified in nasopharyngeal samples from patients with signs of respiratory infections. These viruses may cause mild to life-threatening infections. ...
journal_title：European journal of medical research
pub_type： 杂志文章
doi：
更新日期：2007-03-26 00:00:00
abstract：BACKGROUND:Since the new 2009 guidelines for left subclavian artery (LSA) management using thoracic endovascular aortic repair (TEVAR), a few studies have been published about alternative LSA management. The objective of this study was to present the follow-up results of covered or revascularized LSA during TEVAR. MET...
journal_title：European journal of medical research
pub_type： 杂志文章
doi：10.1186/s40001-015-0147-z
更新日期：2015-05-31 00:00:00
abstract：:In 1973 copper-associated liver disease was first described in an Australian boy of non-Indian origin who died at the age of 15 months with liver cirrhosis. At necropsy the hepatic copper concentration was excessively high (> 300 mg/g dry weight). It was shown that the boy s disease was caused by consumption of copper...
journal_title：European journal of medical research
pub_type： 历史文章,杂志文章
doi：
更新日期：1999-06-28 00:00:00
abstract：OBJECTIVES:To report an extremely rare case of ovarian borderline mucinous cystic tumor accompanied by low-grade endometrial stromal sarcoma (LGESS) with myxoid change. CASE PRESENTATION:A 42-year-old woman complained of lower left abdominal fullness. Her serum carcinoembryonic antigen, cancer antigen (CA) 125, and CA...
journal_title：European journal of medical research
pub_type： 杂志文章,评审
doi：10.1186/s40001-017-0295-4
更新日期：2017-12-02 00:00:00
abstract：BACKGROUND:This study investigates the effects of human bone marrow-derived mesenchymal stem cell (hMSC) on migration and proliferation ability of hepatocellular carcinoma (HCC) with high- and low-metastatic potential. METHODS:The hMSC and transforming growth factor-β1 (TGFβ-1) gene infected hMSC were co-cultured with...
journal_title：European journal of medical research
pub_type： 杂志文章
doi：10.1186/s40001-015-0144-2
更新日期：2015-05-24 00:00:00
abstract：:Under antidepressive treatment with amitryptiline (100 mg/d) a 71-year old woman developed delirious symptoms, hyponatremia and a grand mal seizure followed by cardiovascular arrest. A few month later she ingested 48 mg reboxetine with suicidal intent. Overdosing of reboxetine, a selective noradrenaline re-uptake inhi...
journal_title：European journal of medical research
pub_type： 杂志文章
doi：
更新日期：2002-09-30 00:00:00
abstract：INTRODUCTION:Carcinoma of the collecting ducts of Bellini of the kidney (CDC) is very rare but among the most aggressive urological entities. Standard therapy is not well defined with questionable efficacy. METHODS:We present two cases of male patients (49 and 66 years old) with pT3a pN2 CDC treated with a combination...
journal_title：European journal of medical research
pub_type： 杂志文章
doi：
更新日期：2008-11-24 00:00:00
abstract：SUBJECT:Recent studies have shown that smoking and drinking are associated with poorer outcomes in patients with cardiomyopathy. The purpose of this study was to determine all-cause mortality in dilated cardiomyopathy (DCM) associated with smoking and drinking. METHODS:An observational cohort study was undertaken in D...
journal_title：European journal of medical research
pub_type： 杂志文章
doi：10.1186/s40001-015-0171-z
更新日期：2015-09-17 00:00:00
abstract：OBJECTIVE:Evaluating the effects of prophylactic administration of IgM-enriched immunoglobulins (IVIG) on immunological- and clinical parameters in cardiac surgical patients. PATIENTS AND METHODS:41 patients were randomized to receive either an IgM-enriched immunoglobulin (Pentaglobin(R)) preparation (1,300 ml immunog...
journal_title：European journal of medical research
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：2002-12-17 00:00:00
abstract：OBJECTIVE:Due to the side effects of antiretroviral therapy and long term survival there is an increasing concern of an elevated rate of cardiovascular diseases in HIV-infected patients. The present study analysed the cardiovascular risk profile and the probability of cardiovascular events in HIV-infected patients, due...
journal_title：European journal of medical research
pub_type： 杂志文章
doi：
更新日期：2004-02-27 00:00:00
abstract：:The insulin-like and vasodilatatory polypeptide relaxin (RLX), formerly known as a pregnancy hormone, has gained interest as a potential humoral mediator in human heart failure. Controversy exists about the relation between plasma levels of RLX and the severity of heart failure. The present study was designed to deter...
journal_title：European journal of medical research
pub_type： 杂志文章
doi：10.1186/2047-783x-14-3-106
更新日期：2009-03-17 00:00:00
abstract：:Over the last years the reality surrounding HIV-infection has undergone a considerable change with regard to the life expectancy of patients, and the plans they can make for their lives. Because the majority of the HIV positive population is of reproductive age, one of these plans might be to have children, often as a...
journal_title：European journal of medical research
pub_type： 杂志文章
doi：
更新日期：2001-07-30 00:00:00
abstract：OBJECTIVE:The aim of this study was to evaluate the efficacy and safety of composite extracts in reducing weight, as the main outcome measure. Secondary measures of the study were body composition change. DESIGN:Randomised, double blind, placebo-controlled clinical trial. SETTING:Tertiary university clinic. SUBJECTS...
journal_title：European journal of medical research
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：2006-08-30 00:00:00
abstract：BACKGROUND:Prophylaxis efforts for the maintenance of tooth health led to a distinctive decrease in caries frequency with children and young persons. Because the toothbrush can still be described as the most important oral hygiene aid, possible differences between the effectivity of electric and manual toothbrushes sho...
journal_title：European journal of medical research
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：2001-01-29 00:00:00
abstract：OBJECTIVE:Efavirenz (EFV) plasma levels have been discussed as a predictor of treatment failure in HIV infected patients. The aim of this prospective, open-labeled, case-control study was to evaluate pretreated patients in regards to efavirenz plasma levels and efficacy of therapy. METHODS:Blood samples were obtained ...
journal_title：European journal of medical research
pub_type： 临床试验,杂志文章
doi：
更新日期：2002-07-24 00:00:00
abstract：BACKGROUND:The literature did not show clearly if a correlation between trunk and facial asymmetry exists. The aim of this study was to verify the association between trunk and facial asymmetries, and trunk and facial sagittal configuration in adolescents. METHODS:This is a cross-sectional screening study. It was carr...
journal_title：European journal of medical research
pub_type： 杂志文章
doi：10.1186/s40001-017-0280-y
更新日期：2017-09-29 00:00:00
abstract：BACKGROUND:Congenital fibrosis of the extraocular muscles type 1 (CFEOM1) is a congenital, non-progressive autosomal-dominant disorder with bilateral oculomotor nerve palsy due to mutations in the kinesin motor protein gene KIF21A. - RESULTS:We present a 60-year old patient with CFEOM1 due to the common C2860T mutatio...
journal_title：European journal of medical research
pub_type： 杂志文章
doi：
更新日期：2005-08-17 00:00:00
abstract：INTRODUCTION:Mitochondrial dysfunction plays a central role in the general pathogenesis of non-alcoholic fatty liver disease (NAFLD), increasing the risk of developing steatosis and subsequent hepatocellular inflammation. We aimed to assess hepatic mitochondrial function by a non-invasive (13)C-methionine breath test (...
journal_title：European journal of medical research
pub_type： 杂志文章
doi：10.1186/2047-783x-16-6-258
更新日期：2011-06-21 00:00:00
