Abstract:
:Fluid shift after entering into microgravity, but also under equivalent flight conditions leads to enormous increase of intraocular pressure. To assess this precisely position - and gravity independent, handsome, automatic tonometers have been developed (German-Spacelab D1-Mission, German-Spacelab D2-Mission, German-Russian-MIR-Mission) telemetric transmission of measuring results of course would find scientific but also functional interest. The same is true for recently designed automatic intraocular pressure sensors, registering intraocular pressure continuously, day and night. Also recently designed new automatic ophthalmodynamometer, allowing directly to assess the intracranial pressure, but also perfusion pressure within the eye also could benefit from a direct telemetric transmission. New technical solutions allowing for the first time even telematic data transmission, are reported.
journal_name
Eur J Med Resjournal_title
European journal of medical researchauthors
Draeger J,Michelson G,Rumberger Esubject
Has Abstractpub_date
2000-01-26 00:00:00pages
2-4issue
1eissn
0949-2321issn
2047-783Xjournal_volume
5pub_type
杂志文章abstract::Gadolinium chelates are widely used in magnetic resonance imaging as contrast medium in patients with nephropathy. However, only few studies have investigated the effect of gadolinium on serum creatinine concentration and estimated GFR as surrogate markers of renal function. This study was performed to evaluate the ef...
journal_title:European journal of medical research
pub_type: 杂志文章
doi:
更新日期:2005-04-20 00:00:00
abstract::Plexiform neurofibroma (PN) is a rare benign tumor and a special subtype of neurofibromatosis type 1 (NF1). Though the incidence is low, giant PN of the craniomaxillofacial region could result in severe hemifacial hypertrophy which is known as a typical manifestation of NF1 in young children. Here, we retrospectively ...
journal_title:European journal of medical research
pub_type: 杂志文章
doi:10.1186/2047-783x-15-2-84
更新日期:2010-02-26 00:00:00
abstract::Experiments in space have shown that T lymphocyte function is altered in more than 50% of space crew members. There is strong evidence that such effect is due to stress rather than to weightlessness per se. However the health of astronauts was never threatened so far. Experiments in-vitro with cultures of human periph...
journal_title:European journal of medical research
pub_type: 杂志文章
doi:
更新日期:1999-09-09 00:00:00
abstract:BACKGROUND:Renal impairment is a common complication of multiple myeloma occurring in up to 50 % of patients at some stage in their disease. Due to occurrence of cast nephropathies we hypothesized circulatory dysregulation (vasoconstriction) in the kidneys with measurable elevation of the resistance index among these p...
journal_title:European journal of medical research
pub_type: 杂志文章
doi:10.1186/2047-783x-15-5-210
更新日期:2010-05-18 00:00:00
abstract:BACKGROUND:Hereditary non-polyposis colorectal cancer (HNPCC) is an autosomal dominant tumor syndrome predisposing to predominantly colorectal and endometrial cancer. In 90% of the cases, molecular analyses reveal microsatellite instabilities due to germline mutations in DNA mismatch repair (MMR) genes, mainly MLH1, MS...
journal_title:European journal of medical research
pub_type: 杂志文章
doi:
更新日期:2005-01-28 00:00:00
abstract::Polyadenosylation of nuclear enzymes is well known to regulate the cellular repair capacity after DNA damage. PARP mediates the transfer of poly-ADP-ribose moieties on itself and other nuclear proteins by the breakdown of NAD+. The present study investigated how modulation of PARP activity interferes with cell death i...
journal_title:European journal of medical research
pub_type: 杂志文章
doi:
更新日期:2003-10-22 00:00:00
abstract:BACKGROUND:Children with persistent mild to moderate bronchial asthma require anti-inflammatory therapy. According to current treatment guidelines both sodium cromoglycate (SCG) and inhaled corticosteroids can be used. If children remain symptomatic despite regular SCG therapy, corticosteroids are the next therapeutic ...
journal_title:European journal of medical research
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:2002-06-28 00:00:00
abstract::Bacteremia due to Capnocytophaga sputigena occurred in a 4-year and 9-month-old Japanese girl patient with acute erythroblastic leukemia in Shinshu University Hospital, Japan. On her admission to the hospital, she had a temperature of 38.2 degrees C with canker sore. Prior to the commencement of chemotherapy, peripher...
journal_title:European journal of medical research
pub_type: 杂志文章
doi:
更新日期:2008-03-31 00:00:00
abstract::CCR5 receptor inhibitors are currently being introduced into clinical practice. In some instances treatment failure is related to the selection of pre-existing CXCR4-tropic minority virus strains. Up to date it is unclear whether the outgrowth of a CXCR4 using reservoir is associated with accelerated HIV-disease. In a...
journal_title:European journal of medical research
pub_type: 杂志文章,评审
doi:
更新日期:2007-10-15 00:00:00
abstract:SUBJECT:Recent studies have shown that smoking and drinking are associated with poorer outcomes in patients with cardiomyopathy. The purpose of this study was to determine all-cause mortality in dilated cardiomyopathy (DCM) associated with smoking and drinking. METHODS:An observational cohort study was undertaken in D...
journal_title:European journal of medical research
pub_type: 杂志文章
doi:10.1186/s40001-015-0171-z
更新日期:2015-09-17 00:00:00
abstract:BACKGROUND:A great variety of dental materials are now available for use in restorative treatments. Much attention has been devoted to physical and chemical properties, but the biological effects of these materials have been less frequently studied. AIM:The aim of this study is to test the influence of resin based res...
journal_title:European journal of medical research
pub_type: 杂志文章
doi:
更新日期:2001-10-29 00:00:00
abstract::Targeted intrapulmonary delivery of drugs may reduce systemic toxicity, improve treatment efficacy, but inhaled drugs may also interfere with pulmonary surfactant function. We hypothesized that the lipophilic drug amphotericin B used to treat or prevent pulmonary infections with aspergillus species, might destroy surf...
journal_title:European journal of medical research
pub_type: 杂志文章
doi:
更新日期:1998-08-18 00:00:00
abstract:BACKGROUND:Burkholderia cepacia strains have been known to possess the capability to cause serious infections especially in neonatal intensive care units (NICUs), and their multi-drug resistances become a severe threat in hospital settings. The aim of this investigation was to evaluate the B. cepacia complex infections...
journal_title:European journal of medical research
pub_type: 杂志文章
doi:10.1186/2047-783x-16-12-537
更新日期:2011-12-02 00:00:00
abstract:INTRODUCTION:Carcinoma of the collecting ducts of Bellini of the kidney (CDC) is very rare but among the most aggressive urological entities. Standard therapy is not well defined with questionable efficacy. METHODS:We present two cases of male patients (49 and 66 years old) with pT3a pN2 CDC treated with a combination...
journal_title:European journal of medical research
pub_type: 杂志文章
doi:
更新日期:2008-11-24 00:00:00
abstract::Determination of fecal excretion of the serum proteinase inhibitor alpha(1)-antitrypsin (AAT) is established for quantification of intestinal protein loss. It was demonstrated to be increased both in quiescent and in active inflammatory bowel diseases (IBD, Crohn's disease and ulcerative colitis). The (patho)physiolog...
journal_title:European journal of medical research
pub_type: 杂志文章,评审
doi:
更新日期:1998-02-21 00:00:00
abstract:PURPOSE:Evaluation of MR-guided interstitial laser thermotherapy (ILT) of colorectal liver metastases under consideration of efficacy, safety and patient survival. MATERIALS AND METHODS:Sixty-six inoperable patients with a total of 117 colorectal liver metastases were treated with MR-guided laser therapy in 96 session...
journal_title:European journal of medical research
pub_type: 杂志文章
doi:
更新日期:2007-04-26 00:00:00
abstract::The influence of heparin on Polymorphonuclear (PMN s) leukocytes was investigated using a new whole-blood cytofluorometric method (patent granted for the test with the number P 4334935.8-41) with Candida albicans and Staphylococcus aureus as test microorganisms. After comparing the effect of equal volumes of two widel...
journal_title:European journal of medical research
pub_type: 杂志文章
doi:
更新日期:1997-12-31 00:00:00
abstract::The gum resin of Boswellia serrata, known in Indian Ayurvedic system of medicine as Salai guggal, contains boswellic acids, which have been shown to inhibit leukotriene biosynthesis. In a double-blind, placebo-controlled study forty patients, 23 males and 17 females in the age range of 18 - 75 years having mean durati...
journal_title:European journal of medical research
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1998-11-17 00:00:00
abstract:BACKGROUND:In intestinal epithelium, tyrosine kinase receptor Ephrin B3 (Eph B3) maintains the architecture of the crypt-villus axis by repulsive interaction with its ligand ephrin-B1. While loss of Eph B3 is linked to colorectal cancer initiation, overexpression of Eph B3 in cancer cell lines inhibits growth and induc...
journal_title:European journal of medical research
pub_type: 杂志文章
doi:10.1186/2047-783X-17-10
更新日期:2012-05-14 00:00:00
abstract:BACKGROUND:Multiple severe trauma frequently leads to massive dysbalances of the human immune system. This phenomenon is known as "Systemic Inflammatory Response Syndrome (SIRS)". SIRS is connected to multiple organ failure and thereby entails higher morbidity and mortality in trauma patients. Pro- and anti-inflammator...
journal_title:European journal of medical research
pub_type: 杂志文章
doi:10.1186/2047-783x-14-7-284
更新日期:2009-07-22 00:00:00
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journal_title:European journal of medical research
pub_type: 杂志文章
doi:10.1186/s40001-017-0300-y
更新日期:2018-01-08 00:00:00
abstract::More than one quarter of total daily calories are normally provided by fatty acids which contain at least one double bond. The usual configuration of these double bonds is the cis configuration. Trans fatty acids (TFA) are formed in technological and microbiological processes by isomerization of cis double bonds to tr...
journal_title:European journal of medical research
pub_type: 杂志文章,评审
doi:
更新日期:2003-08-20 00:00:00
abstract:OBJECTIVE:The aim of this study was to evaluate the efficacy and safety of composite extracts in reducing weight, as the main outcome measure. Secondary measures of the study were body composition change. DESIGN:Randomised, double blind, placebo-controlled clinical trial. SETTING:Tertiary university clinic. SUBJECTS...
journal_title:European journal of medical research
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:2006-08-30 00:00:00
abstract:BACKGROUND:Breast cancer risk prediction models are widely used in clinical settings. Although most of the well-known models were designed based on data collected from western population, yet they have been utilized for surveillance purposes in many limited-resource countries. Given the genetic variations in risk facto...
journal_title:European journal of medical research
pub_type: 杂志文章,多中心研究
doi:10.1186/s40001-017-0277-6
更新日期:2017-09-29 00:00:00
abstract:BACKGROUND:This study investigates the effects of human bone marrow-derived mesenchymal stem cell (hMSC) on migration and proliferation ability of hepatocellular carcinoma (HCC) with high- and low-metastatic potential. METHODS:The hMSC and transforming growth factor-β1 (TGFβ-1) gene infected hMSC were co-cultured with...
journal_title:European journal of medical research
pub_type: 杂志文章
doi:10.1186/s40001-015-0144-2
更新日期:2015-05-24 00:00:00
abstract::The 825T-allele of the C825T polymorphism in GNB3, the gene for the G protein beta3 subunit, has been reported to be associated with essential hypertension and obesity. Expression of Gbeta3s, the gene product of GNB3 associated with the GNB3 825T-allele, causes increased signal transduction which may contribute to pat...
journal_title:European journal of medical research
pub_type: 杂志文章
doi:
更新日期:2003-03-27 00:00:00
abstract:BACKGROUND:The literature did not show clearly if a correlation between trunk and facial asymmetry exists. The aim of this study was to verify the association between trunk and facial asymmetries, and trunk and facial sagittal configuration in adolescents. METHODS:This is a cross-sectional screening study. It was carr...
journal_title:European journal of medical research
pub_type: 杂志文章
doi:10.1186/s40001-017-0280-y
更新日期:2017-09-29 00:00:00
abstract:BACKGROUND:Resternotomy in cardiac surgery is considered a risk factor for postoperative complications. Previous studies have demonstrated an ambiguous relationship between resternotomy and clinical outcomes. Registry data from a mixed population of durable circulatory support devices suggest that history of cardiac su...
journal_title:European journal of medical research
pub_type: 杂志文章
doi:10.1186/s40001-017-0289-2
更新日期:2017-11-15 00:00:00
abstract::The purpose of this report is to document a case of unsuspected ameloblastoma involving the right man dibular subpontic region in a 38-year-old Cambodian female patient. This lesion was purportedly preceded by multiple radiolucencies which were diagnosed as radicular cysts and treated a few times in the past years by ...
journal_title:European journal of medical research
pub_type: 杂志文章
doi:10.1186/2047-783x-15-3-135
更新日期:2010-03-30 00:00:00
abstract::Right ventricle (RV) dysfunction is a key outcome determinant and a leading cause of death for patients with chronic thromboembolic pulmonary hypertension (CTEPH). In this report, we followed the 5-year clinical journey of a patient with CTEPH. The tricuspid pressure gradient was significantly increased in the early p...
journal_title:European journal of medical research
pub_type: 杂志文章
doi:10.1186/s40001-015-0112-x
更新日期:2015-03-02 00:00:00