Abstract：
:Human observers adapted to complex biological motions that distinguish males from females: viewing the gait of one gender biased judgments of subsequent gaits toward the opposite gender. This adaptation was not simply due to local features of the stimuli but instead relied upon the global motion of the figures. These results suggest the existence of neurons selective for gender and demonstrate that gender-from-motion judgments are not fixed but depend upon recent viewing history.
journal_name
Nat Neuroscijournal_title
Nature neuroscienceauthors
Jordan H,Fallah M,Stoner GRdoi
10.1038/nn1710subject
Has Abstractpub_date
2006-06-01 00:00:00pages
738-9issue
6eissn
1097-6256issn
1546-1726pii
nn1710journal_volume
9pub_type
杂志文章abstract：:A hallmark event in neurodegenerative diseases (NDs) is the misfolding, aggregation, and accumulation of proteins, leading to cellular dysfunction, loss of synaptic connections, and brain damage. Despite the involvement of distinct proteins in different NDs, the process of protein misfolding and aggregation is remarka...
journal_title：Nature neuroscience
pub_type： 杂志文章,评审
doi：10.1038/s41593-018-0235-9
更新日期：2018-10-01 00:00:00
abstract：:Fast desensitization is an important regulatory mechanism of neuronal NMDA receptor function. Only recombinant NMDA receptors composed of NR1/NR2A exhibit a fast component of desensitization similar to neuronal NMDA receptors. Here we report that the fast desensitization of NR1/NR2A receptors is caused by ambient zinc...
journal_title：Nature neuroscience
pub_type： 杂志文章
doi：10.1038/nn0901-894
更新日期：2001-09-01 00:00:00
abstract：:Growing evidence suggests that the recognition of different emotional states involves at least partly separable neural circuits. Here we assessed the discrimination of both anger and happiness in healthy subjects receiving transcranial magnetic stimulation (TMS) over the medial-frontal cortex or over a control site (m...
journal_title：Nature neuroscience
pub_type： 临床试验,杂志文章
doi：10.1038/82854
更新日期：2001-01-01 00:00:00
abstract：:Exposure to an enriched environment increases neurogenesis in the dentate gyrus of adult rodents. Environmental enrichment, however, typically consists of many components, such as expanded learning opportunities, increased social interaction, more physical activity and larger housing. We attempted to separate componen...
journal_title：Nature neuroscience
pub_type： 杂志文章
doi：10.1038/6368
更新日期：1999-03-01 00:00:00
abstract：:Cannabis is the most frequently used illicit psychoactive substance worldwide; around one in ten users become dependent. The risk for cannabis use disorder (CUD) has a strong genetic component, with twin heritability estimates ranging from 51 to 70%. Here we performed a genome-wide association study of CUD in 2,387 ca...
journal_title：Nature neuroscience
pub_type： 杂志文章
doi：10.1038/s41593-019-0416-1
更新日期：2019-07-01 00:00:00
abstract：:Many cells in retinotopic brain areas increase their activity when saccades (rapid eye movements) are about to bring stimuli into their receptive fields. Although previous work has attempted to look at the functional correlates of such predictive remapping, no study has explicitly tested for better attentional perform...
journal_title：Nature neuroscience
pub_type： 杂志文章
doi：10.1038/nn.2711
更新日期：2011-02-01 00:00:00
abstract：:The olfactory system faces a hard problem: on the basis of noisy information from olfactory receptor neurons (the neurons that transduce chemicals to neural activity), it must figure out which odors are present in the world. Odors almost never occur in isolation, and different odors excite overlapping populations of o...
journal_title：Nature neuroscience
pub_type： 杂志文章
doi：10.1038/nn.4444
更新日期：2017-01-01 00:00:00
abstract：:The ability to attribute mental states to others, and therefore to predict others' behavior, is particularly advanced in humans. A controversial but untested idea is that this is achieved by simulating the other person's mental processes in one's own mind. If this is the case, then the same neural systems activated by...
journal_title：Nature neuroscience
pub_type： 杂志文章
doi：10.1038/nn1168
更新日期：2004-01-01 00:00:00
abstract：:Images are processed in the primary visual cortex by neurons that encode different stimulus orientations and spatial phases. In primates and carnivores, neighboring cortical neurons share similar orientation preferences, but spatial phases were thought to be randomly distributed. We discovered a columnar organization ...
journal_title：Nature neuroscience
pub_type： 杂志文章
doi：10.1038/nn.3878
更新日期：2015-01-01 00:00:00
abstract：:Selective attention filters information to limit what is encoded and maintained in working memory. Although the prefrontal cortex (PFC) is central to both selective attention and working memory, the underlying neural processes that link these cognitive abilities remain elusive. Using functional magnetic resonance imag...
journal_title：Nature neuroscience
pub_type： 杂志文章
doi：10.1038/nn.2773
更新日期：2011-05-01 00:00:00
abstract：:Fear renewal, a widely pursued model of post-traumatic stress disorder and phobias, refers to the context-specific relapse of conditioned fear after extinction. However, its molecular mechanisms are largely unknown. We found that renewal-inducing stimuli, generally believed to be insufficient to induce synaptic plasti...
journal_title：Nature neuroscience
pub_type： 杂志文章
doi：10.1038/nn.3491
更新日期：2013-10-01 00:00:00
abstract：:We argue that there will be no single (genetic or cognitive) cause for the diverse symptoms defining autism. We present recent evidence of behavioral fractionation of social impairment, communication difficulties and rigid and repetitive behaviors. Twin data suggest largely nonoverlapping genes acting on each of these...
journal_title：Nature neuroscience
pub_type： 杂志文章,评审
doi：10.1038/nn1770
更新日期：2006-10-01 00:00:00
abstract：:The melanocortin system provides a conceptual blueprint for the central control of energetic state. Defined by four principal molecular components--two antagonistically acting ligands and two cognate receptors--this phylogenetically conserved system serves as a prototype for hierarchical energy balance regulation. Ove...
journal_title：Nature neuroscience
pub_type： 杂志文章,评审
doi：10.1038/nn.4202
更新日期：2016-02-01 00:00:00
abstract：:The endocytosis of AMPA receptors is thought to be important in the expression of long-term depression (LTD) triggered by NMDA receptor activation. Although signaling pathways necessary for LTD induction have been identified, those responsible for the regulated internalization of AMPA receptors are unknown. Here we sh...
journal_title：Nature neuroscience
pub_type： 杂志文章
doi：10.1038/81823
更新日期：2000-12-01 00:00:00
abstract：:Imaging, from magnetic resonance imaging (MRI) to localization of specific macromolecules by microscopies, has been one of the driving forces behind neuroinformatics efforts of the past decade. Many web-accessible resources have been created, ranging from simple data collections to highly structured databases. Althoug...
journal_title：Nature neuroscience
pub_type： 杂志文章
doi：10.1038/nn1229
更新日期：2004-05-01 00:00:00
abstract：:The painful sensations produced by a laceration, freeze, burn, muscle strain or internal injury are readily distinguishable because each is characterized by a particular sensory quality such as sharp, aching, burning or prickling. We propose that there are specific neural correlates of each pain quality, and here we u...
journal_title：Nature neuroscience
pub_type： 杂志文章
doi：10.1038/nn955
更新日期：2002-11-01 00:00:00
abstract：:The excitability of individual dendritic branches is a plastic property of neurons. We found that experience in an enriched environment increased propagation of dendritic Na(+) spikes in a subset of individual dendritic branches in rat hippocampal CA1 pyramidal neurons and that this effect was mainly mediated by local...
journal_title：Nature neuroscience
pub_type： 杂志文章
doi：10.1038/nn.2428
更新日期：2009-12-01 00:00:00
abstract：:Mutations in copper/zinc superoxide dismutase 1 (SOD1), primary causes of human amyotrophic lateral sclerosis (ALS), provoke motor neuron death through an unidentified toxic property. The known neurofilament-dependent slowing of axonal transport, combined with the prominent misaccumulation of neurofilaments in ALS, su...
journal_title：Nature neuroscience
pub_type： 杂志文章
doi：10.1038/4553
更新日期：1999-01-01 00:00:00
abstract：:Replay of hippocampal place cell sequences has been proposed as a fundamental mechanism of learning and memory. However, the standard interpretation of replay has been challenged by reports that similar activity is observed before experience ('preplay'). By the preplay account, pre-existing temporal sequences are mapp...
journal_title：Nature neuroscience
pub_type： 杂志文章
doi：10.1038/nn.4151
更新日期：2015-12-01 00:00:00
abstract：:The production of hippocampal granule neurons continues throughout adulthood but dramatically decreases in old age. Here we show that reducing corticosteroid levels in aged rats restored the rate of cell proliferation, resulting in increased numbers of new granule neurons. This result indicates that the neuronal precu...
journal_title：Nature neuroscience
pub_type： 杂志文章
doi：10.1038/13197
更新日期：1999-10-01 00:00:00
abstract：:Using multimodal neuroimaging in humans, we demonstrate specific interactions between prefrontal activity and midbrain dopaminergic synthesis. A common V(108/158)M substitution in the gene for catecholamine-O-methyltransferase (COMT), an important enzyme regulating prefrontal dopamine turnover, predicted reduced dopam...
journal_title：Nature neuroscience
pub_type： 杂志文章
doi：10.1038/nn1438
更新日期：2005-05-01 00:00:00
abstract：:Electrical stimulation of visual cortex can produce a visual percept (phosphene). We electrically stimulated visual cortex in humans implanted with subdural electrodes while recording from other brain sites. Phosphene perception occurred only if stimulation evoked high-frequency gamma oscillations in the temporopariet...
journal_title：Nature neuroscience
pub_type： 杂志文章
doi：10.1038/nn.3131
更新日期：2012-06-03 00:00:00
abstract：:Neuronal differentiation is accomplished through cascades of intrinsic genetic factors initiated in neuronal progenitors by external gradients of morphogens. Activity has been thought to be important only late in development, but recent evidence suggests that activity also regulates early neuronal differentiation. Act...
journal_title：Nature neuroscience
pub_type： 杂志文章
doi：10.1038/nn.2582
更新日期：2010-08-01 00:00:00
abstract：:Transposable elements, known colloquially as 'jumping genes', constitute approximately 45% of the human genome. Cells utilize epigenetic defenses to limit transposable element jumping, including formation of silencing heterochromatin and generation of piwi-interacting RNAs (piRNAs), small RNAs that facilitate clearanc...
journal_title：Nature neuroscience
pub_type： 杂志文章
doi：10.1038/s41593-018-0194-1
更新日期：2018-08-01 00:00:00
abstract：:Memory reconsolidation has been demonstrated in various tasks and species, suggesting it is a fundamental process. However, there are experimental parameters that can inhibit reconsolidation from occurring (boundary conditions). These conditions and their mechanisms remain poorly defined. Here, we characterize the abi...
journal_title：Nature neuroscience
pub_type： 杂志文章
doi：10.1038/nn.2350
更新日期：2009-07-01 00:00:00
abstract：:Axon degeneration is a hallmark of many neurodegenerative disorders. The current assumption is that the decision of injured axons to degenerate is cell-autonomously regulated. Here we show that Schwann cells (SCs), the glia of the peripheral nervous system, protect injured axons by virtue of a dramatic glycolytic upre...
journal_title：Nature neuroscience
pub_type： 杂志文章
doi：10.1038/s41593-020-0689-4
更新日期：2020-10-01 00:00:00
abstract：:It is widely believed that attention selects locations at an earlier stage than it selects nonspatial features, but this has been tested only under conditions of minimal competition. We found that, when competition was increased, color-based attention was able to influence the feedforward flow of information in humans...
journal_title：Nature neuroscience
pub_type： 杂志文章
doi：10.1038/nn.2223
更新日期：2009-01-01 00:00:00
abstract：:Neuregulin 1 type III is processed following regulated intramembrane proteolysis, which allows communication from the plasma membrane to the nucleus. We found that the intracellular domain of neuregulin 1 type III upregulated the prostaglandin D2 synthase (L-pgds, also known as Ptgds) gene, which, together with the G ...
journal_title：Nature neuroscience
pub_type： 杂志文章
doi：10.1038/nn.3857
更新日期：2014-12-01 00:00:00
abstract：:Brain-derived neurotrophic factor (BDNF) acting through the tyrosine kinase B receptor (TrkB) is thought to be a critical mediator of learning. As there are no available selective antagonists of TrkB, we used a lentivirus encoding a dominant-negative TrkB (TrkB.t1) to antagonize BDNF signaling during extinction of con...
journal_title：Nature neuroscience
pub_type： 杂志文章
doi：10.1038/nn1718
更新日期：2006-07-01 00:00:00
abstract：:Dendritic spines undergo actin-based growth and shrinkage during synaptic plasticity, in which the actin depolymerizing factor (ADF)/cofilin family of actin-associated proteins are important. Elevated ADF/cofilin activities often lead to reduced spine size and immature spine morphology but can also enhance synaptic po...
journal_title：Nature neuroscience
pub_type： 杂志文章
doi：10.1038/nn.2634
更新日期：2010-10-01 00:00:00
