Abstract：
:We studied how the posterior parietal cortex combines new information with ongoing activity dynamics as mice accumulate evidence during a virtual navigation task. Using new methods to analyze population activity on single trials, we found that activity transitioned rapidly between different sets of active neurons. Each event in a trial, whether an evidence cue or a behavioral choice, caused seconds-long modifications to the probabilities that govern how one activity pattern transitions to the next, forming a short-term memory. A sequence of evidence cues triggered a chain of these modifications resulting in a signal for accumulated evidence. Multiple distinguishable activity patterns were possible for the same accumulated evidence because representations of ongoing events were influenced by previous within- and across-trial events. Therefore, evidence accumulation need not require the explicit competition between groups of neurons, as in winner-take-all models, but could instead emerge implicitly from general dynamical properties that instantiate short-term memory.
journal_name
Nat Neuroscijournal_title
Nature neuroscienceauthors
Morcos AS,Harvey CDdoi
10.1038/nn.4403subject
Has Abstractpub_date
2016-12-01 00:00:00pages
1672-1681issue
12eissn
1097-6256issn
1546-1726pii
nn.4403journal_volume
19pub_type
杂志文章abstract：:The most critical attribute of human language is its unbounded combinatorial nature: smaller elements can be combined into larger structures on the basis of a grammatical system, resulting in a hierarchy of linguistic units, such as words, phrases and sentences. Mentally parsing and representing such structures, howev...
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