当前位置： SCI文献检索 > NATURE NEUROSCIENCE期刊下所有文献 > The hippocampus is necessary for enhancements and impairments of learning following stress.

The hippocampus is necessary for enhancements and impairments of learning following stress.

Abstract：

:The hippocampus is often considered to be an important site for stress and learning interactions; however, it has never been demonstrated whether these effects require the hippocampus. In the current study, hippocampal lesions prevented both enhancements of learning after stress in male rats and impairments of learning after stress in female rats without disrupting learning itself in either sex. Thus, the hippocampus is necessary for modifying learning in males and females after acute stressful experience.

journal_name

Nat Neurosci

journal_title

Nature neuroscience

authors

Bangasser DA,Shors TJ

doi

10.1038/nn1973

subject

Has Abstract

pub_date

2007-11-01 00:00:00

pages

1401-3

issue

11

eissn

1097-6256

issn

1546-1726

pii

nn1973

journal_volume

10

pub_type

杂志文章

相关文献

NATURE NEUROSCIENCE文献大全
  • Synchrony-dependent propagation of firing rate in iteratively constructed networks in vitro.

    abstract：:The precise role of synchronous neuronal firing in signal encoding remains unclear. To examine what kinds of signals can be carried by synchrony, I reproduced a multilayer feedforward network of neurons in an in vitro slice preparation of rat cortex using an iterative procedure. When constant and time-varying frequenc...

    journal_title：Nature neuroscience

    pub_type： 杂志文章

    doi：10.1038/nn1056

    authors： Reyes AD

    更新日期：2003-06-01 00:00:00

  • Getting a bead on receptor movements.

    abstract：:Studies of populations of receptor proteins suggest that their number and location are highly regulated. Single-particle tracking of glycine receptors now reveals the direct movement of receptors between different clusters of the anchoring protein gephyrin. ...

    journal_title：Nature neuroscience

    pub_type： 评论,杂志文章,评审

    doi：10.1038/85042

    authors： Craig AM,Lichtman JW

    更新日期：2001-03-01 00:00:00

  • A GABAergic nigrotectal pathway for coordination of drinking behavior.

    abstract：:The contribution of basal ganglia outputs to consummatory behavior remains poorly understood. We recorded from the substantia nigra pars reticulata (SNR), the major basal ganglia output nucleus, during self-initiated drinking in mice. The firing rates of many lateral SNR neurons were time-locked to individual licks. T...

    journal_title：Nature neuroscience

    pub_type： 杂志文章

    doi：10.1038/nn.4285

    authors： Rossi MA,Li HE,Lu D,Kim IH,Bartholomew RA,Gaidis E,Barter JW,Kim N,Cai MT,Soderling SH,Yin HH

    更新日期：2016-05-01 00:00:00

  • Time to give up on a single explanation for autism.

    abstract：:We argue that there will be no single (genetic or cognitive) cause for the diverse symptoms defining autism. We present recent evidence of behavioral fractionation of social impairment, communication difficulties and rigid and repetitive behaviors. Twin data suggest largely nonoverlapping genes acting on each of these...

    journal_title：Nature neuroscience

    pub_type： 杂志文章,评审

    doi：10.1038/nn1770

    authors： Happé F,Ronald A,Plomin R

    更新日期：2006-10-01 00:00:00

  • Coherent spontaneous activity accounts for trial-to-trial variability in human evoked brain responses.

    abstract：:Trial-to-trial variability in the blood oxygen level-dependent (BOLD) response of functional magnetic resonance imaging has been shown to be relevant to human perception and behavior, but the sources of this variability remain unknown. We demonstrate that coherent spontaneous fluctuations in human brain activity accou...

    journal_title：Nature neuroscience

    pub_type： 临床试验,杂志文章

    doi：10.1038/nn1616

    authors： Fox MD,Snyder AZ,Zacks JM,Raichle ME

    更新日期：2006-01-01 00:00:00

  • Myosin-dependent targeting of transmembrane proteins to neuronal dendrites.

    abstract：:The distinct electrical properties of axonal and dendritic membranes are largely a result of specific transport of vesicle-bound membrane proteins to each compartment. How this specificity arises is unclear because kinesin motors that transport vesicles cannot autonomously distinguish dendritically projecting microtub...

    journal_title：Nature neuroscience

    pub_type： 杂志文章

    doi：10.1038/nn.2318

    authors： Lewis TL Jr,Mao T,Svoboda K,Arnold DB

    更新日期：2009-05-01 00:00:00

  • Circuit dissection of the role of somatostatin in itch and pain.

    abstract：:Stimuli that elicit itch are detected by sensory neurons that innervate the skin. This information is processed by the spinal cord; however, the way in which this occurs is still poorly understood. Here we investigated the neuronal pathways for itch neurotransmission, particularly the contribution of the neuropeptide ...

    journal_title：Nature neuroscience

    pub_type： 杂志文章

    doi：10.1038/s41593-018-0119-z

    authors： Huang J,Polgár E,Solinski HJ,Mishra SK,Tseng PY,Iwagaki N,Boyle KA,Dickie AC,Kriegbaum MC,Wildner H,Zeilhofer HU,Watanabe M,Riddell JS,Todd AJ,Hoon MA

    更新日期：2018-05-01 00:00:00

  • Multiple climbing fibers signal to molecular layer interneurons exclusively via glutamate spillover.

    abstract：:Spillover of glutamate under physiological conditions has only been established as an adjunct to conventional synaptic transmission. Here we describe a pure spillover connection between the climbing fiber and molecular layer interneurons in the rat cerebellar cortex. We show that, instead of acting via conventional sy...

    journal_title：Nature neuroscience

    pub_type： 杂志文章

    doi：10.1038/nn1907

    authors： Szapiro G,Barbour B

    更新日期：2007-06-01 00:00:00

  • Anatomical connectivity patterns predict face selectivity in the fusiform gyrus.

    abstract：:A fundamental assumption in neuroscience is that brain structure determines function. Accordingly, functionally distinct regions of cortex should be structurally distinct in their connections to other areas. We tested this hypothesis in relation to face selectivity in the fusiform gyrus. By using only structural conne...

    journal_title：Nature neuroscience

    pub_type： 杂志文章

    doi：10.1038/nn.3001

    authors： Saygin ZM,Osher DE,Koldewyn K,Reynolds G,Gabrieli JD,Saxe RR

    更新日期：2011-12-25 00:00:00

  • GABAergic mechanisms regulated by miR-33 encode state-dependent fear.

    abstract：:Fear-inducing memories can be state dependent, meaning that they can best be retrieved if the brain states at encoding and retrieval are similar. Restricted access to such memories can present a risk for psychiatric disorders and hamper their treatment. To better understand the mechanisms underlying state-dependent fe...

    journal_title：Nature neuroscience

    pub_type： 杂志文章

    doi：10.1038/nn.4084

    authors： Jovasevic V,Corcoran KA,Leaderbrand K,Yamawaki N,Guedea AL,Chen HJ,Shepherd GM,Radulovic J

    更新日期：2015-09-01 00:00:00

  • Orientation selectivity and the functional clustering of synaptic inputs in primary visual cortex.

    abstract：:The majority of neurons in primary visual cortex are tuned for stimulus orientation, but the factors that account for the range of orientation selectivities exhibited by cortical neurons remain unclear. To address this issue, we used in vivo two-photon calcium imaging to characterize the orientation tuning and spatial...

    journal_title：Nature neuroscience

    pub_type： 杂志文章

    doi：10.1038/nn.4323

    authors： Wilson DE,Whitney DE,Scholl B,Fitzpatrick D

    更新日期：2016-08-01 00:00:00

  • RGS4-dependent attenuation of M4 autoreceptor function in striatal cholinergic interneurons following dopamine depletion.

    abstract：:Parkinson disease is a neurodegenerative disorder whose symptoms are caused by the loss of dopaminergic neurons innervating the striatum. As striatal dopamine levels fall, striatal acetylcholine release rises, exacerbating motor symptoms. This adaptation is commonly attributed to the loss of interneuronal regulation b...

    journal_title：Nature neuroscience

    pub_type： 杂志文章

    doi：10.1038/nn1700

    authors： Ding J,Guzman JN,Tkatch T,Chen S,Goldberg JA,Ebert PJ,Levitt P,Wilson CJ,Hamm HE,Surmeier DJ

    更新日期：2006-06-01 00:00:00

  • Why pictures look right when viewed from the wrong place.

    abstract：:A picture viewed from its center of projection generates the same retinal image as the original scene, so the viewer perceives the scene correctly. When a picture is viewed from other locations, the retinal image specifies a different scene, but we normally do not notice the changes. We investigated the mechanism unde...

    journal_title：Nature neuroscience

    pub_type： 杂志文章

    doi：10.1038/nn1553

    authors： Vishwanath D,Girshick AR,Banks MS

    更新日期：2005-10-01 00:00:00

  • Unique functional properties of somatostatin-expressing GABAergic neurons in mouse barrel cortex.

    abstract：:Neocortical GABAergic neurons have diverse molecular, structural and electrophysiological features, but the functional correlates of this diversity are largely unknown. We found unique membrane potential dynamics of somatostatin-expressing (SOM) neurons in layer 2/3 of the primary somatosensory barrel cortex of awake ...

    journal_title：Nature neuroscience

    pub_type： 杂志文章

    doi：10.1038/nn.3051

    authors： Gentet LJ,Kremer Y,Taniguchi H,Huang ZJ,Staiger JF,Petersen CC

    更新日期：2012-02-26 00:00:00

  • Functional and structural underpinnings of neuronal assembly formation in learning.

    abstract：:Learning and memory are associated with the formation and modification of neuronal assemblies: populations of neurons that encode what has been learned and mediate memory retrieval upon recall. Functional studies of neuronal assemblies have progressed dramatically thanks to recent technological advances. Here we discu...

    journal_title：Nature neuroscience

    pub_type： 杂志文章,评审

    doi：10.1038/nn.4418

    authors： Holtmaat A,Caroni P

    更新日期：2016-12-01 00:00:00

  • Focus on neurodegenerative disease.

    abstract：:Nature Neuroscience presents a special issue of recent advances on shared mechanisms underlying neurodegenerative disease. ...

    journal_title：Nature neuroscience

    pub_type： 社论

    doi：10.1038/s41593-018-0250-x

    authors：

    更新日期：2018-10-01 00:00:00

  • A neuronal PI(3,4,5)P3-dependent program of oligodendrocyte precursor recruitment and myelination.

    abstract：:The molecular trigger of CNS myelination is unknown. By targeting Pten in cerebellar granule cells and activating the AKT1-mTOR pathway, we increased the caliber of normally unmyelinated axons and the expression of numerous genes encoding regulatory proteins. This led to the expansion of genetically wild-type oligoden...

    journal_title：Nature neuroscience

    pub_type： 杂志文章

    doi：10.1038/nn.4425

    authors： Goebbels S,Wieser GL,Pieper A,Spitzer S,Weege B,Yan K,Edgar JM,Yagensky O,Wichert SP,Agarwal A,Karram K,Renier N,Tessier-Lavigne M,Rossner MJ,Káradóttir RT,Nave KA

    更新日期：2017-01-01 00:00:00

  • Stress, genotype and norepinephrine in the prediction of mouse behavior using reinforcement learning.

    abstract：:Individual behavioral performance during learning is known to be affected by modulatory factors, such as stress and motivation, and by genetic predispositions that influence sensitivity to these factors. Despite numerous studies, no integrative framework is available that could predict how a given animal would perform...

    journal_title：Nature neuroscience

    pub_type： 杂志文章

    doi：10.1038/nn.2374

    authors： Luksys G,Gerstner W,Sandi C

    更新日期：2009-09-01 00:00:00

  • The cognitive map in humans: spatial navigation and beyond.

    abstract：:The 'cognitive map' hypothesis proposes that brain builds a unified representation of the spatial environment to support memory and guide future action. Forty years of electrophysiological research in rodents suggest that cognitive maps are neurally instantiated by place, grid, border and head direction cells in the h...

    journal_title：Nature neuroscience

    pub_type： 杂志文章,评审

    doi：10.1038/nn.4656

    authors： Epstein RA,Patai EZ,Julian JB,Spiers HJ

    更新日期：2017-10-26 00:00:00

  • Joint-encoding of motion and depth by visual cortical neurons: neural basis of the Pulfrich effect.

    abstract：:Motion and stereoscopic depth are fundamental parameters of the structural analysis of visual scenes. Because they are defined by a difference in object position, either over time or across the eyes, a common neural machinery may be used for encoding these attributes. To examine this idea, we analyzed responses of bin...

    journal_title：Nature neuroscience

    pub_type： 杂志文章

    doi：10.1038/87462

    authors： Anzai A,Ohzawa I,Freeman RD

    更新日期：2001-05-01 00:00:00

  • Mesopontine median raphe regulates hippocampal ripple oscillation and memory consolidation.

    abstract：:Sharp wave-associated field oscillations (∼200 Hz) of the hippocampus, referred to as ripples, are believed to be important for consolidation of explicit memory. Little is known about how ripples are regulated by other brain regions. We found that the median raphe region (MnR) is important for regulating hippocampal r...

    journal_title：Nature neuroscience

    pub_type： 杂志文章

    doi：10.1038/nn.3998

    authors： Wang DV,Yau HJ,Broker CJ,Tsou JH,Bonci A,Ikemoto S

    更新日期：2015-05-01 00:00:00

  • Activity-dependent site-specific changes of glutamate receptor composition in vivo.

    abstract：:The subunit composition of postsynaptic non-NMDA-type glutamate receptors (GluRs) determines the function and trafficking of the receptor. Changes in GluR composition have been implicated in the homeostasis of neuronal excitability and synaptic plasticity underlying learning. Here, we imaged GluRs in vivo during the f...

    journal_title：Nature neuroscience

    pub_type： 杂志文章

    doi：10.1038/nn.2122

    authors： Schmid A,Hallermann S,Kittel RJ,Khorramshahi O,Frölich AM,Quentin C,Rasse TM,Mertel S,Heckmann M,Sigrist SJ

    更新日期：2008-06-01 00:00:00

  • Mitochondrial control by DRP1 in brain tumor initiating cells.

    abstract：:Brain tumor initiating cells (BTICs) co-opt the neuronal high affinity glucose transporter, GLUT3, to withstand metabolic stress. We investigated another mechanism critical to brain metabolism, mitochondrial morphology, in BTICs. BTIC mitochondria were fragmented relative to non-BTIC tumor cell mitochondria, suggestin...

    journal_title：Nature neuroscience

    pub_type： 杂志文章

    doi：10.1038/nn.3960

    authors： Xie Q,Wu Q,Horbinski CM,Flavahan WA,Yang K,Zhou W,Dombrowski SM,Huang Z,Fang X,Shi Y,Ferguson AN,Kashatus DF,Bao S,Rich JN

    更新日期：2015-04-01 00:00:00

  • Neural correlates of individual differences in affective benefit of real-life urban green space exposure.

    abstract：:Psychiatric morbidity is high in cities, so identifying potential modifiable urban protective factors is important. We show that exposure to urban green space improves well-being in naturally behaving male and female city dwellers, particularly in districts with higher psychiatric incidence and fewer green resources. ...

    journal_title：Nature neuroscience

    pub_type： 杂志文章

    doi：10.1038/s41593-019-0451-y

    authors： Tost H,Reichert M,Braun U,Reinhard I,Peters R,Lautenbach S,Hoell A,Schwarz E,Ebner-Priemer U,Zipf A,Meyer-Lindenberg A

    更新日期：2019-09-01 00:00:00

  • Complex formation between the vasopressin 1b receptor, β-arrestin-2, and the μ-opioid receptor underlies morphine tolerance.

    abstract：:Chronic morphine exposure upregulates adenylate cyclase signaling and reduces analgesic efficacy, a condition known as opioid tolerance. Nonopioid neurotransmitters can enhance morphine tolerance, but the mechanism for this is poorly understood. We show that morphine tolerance was delayed in mice lacking vasopressin 1...

    journal_title：Nature neuroscience

    pub_type： 杂志文章

    doi：10.1038/s41593-018-0144-y

    authors： Koshimizu TA,Honda K,Nagaoka-Uozumi S,Ichimura A,Kimura I,Nakaya M,Sakai N,Shibata K,Ushijima K,Fujimura A,Hirasawa A,Kurose H,Tsujimoto G,Tanoue A,Takano Y

    更新日期：2018-06-01 00:00:00

  • Neuronal remapping and circuit persistence in economic decisions.

    abstract：:The orbitofrontal cortex plays a central role in good-based economic decisions. When subjects make choices, neurons in this region represent the identities and values of offered and chosen goods. Notably, choices in different behavioral contexts may involve a potentially infinite variety of goods. Thus a fundamental q...

    journal_title：Nature neuroscience

    pub_type： 杂志文章

    doi：10.1038/nn.4300

    authors： Xie J,Padoa-Schioppa C

    更新日期：2016-06-01 00:00:00

  • Plasticity of temporal information processing in the primary auditory cortex.

    abstract：:Neurons in the rat primary auditory cortex (A1) generally cannot respond to tone sequences faster than 12 pulses per second (pps). To test whether experience can modify this maximum following rate in adult rats, trains of brief tones with random carrier frequency but fixed repetition rate were paired with electrical s...

    journal_title：Nature neuroscience

    pub_type： 杂志文章

    doi：10.1038/3729

    authors： Kilgard MP,Merzenich MM

    更新日期：1998-12-01 00:00:00

  • Capillary K+-sensing initiates retrograde hyperpolarization to increase local cerebral blood flow.

    abstract：:Blood flow into the brain is dynamically regulated to satisfy the changing metabolic requirements of neurons, but how this is accomplished has remained unclear. Here we demonstrate a central role for capillary endothelial cells in sensing neural activity and communicating it to upstream arterioles in the form of an el...

    journal_title：Nature neuroscience

    pub_type： 杂志文章

    doi：10.1038/nn.4533

    authors： Longden TA,Dabertrand F,Koide M,Gonzales AL,Tykocki NR,Brayden JE,Hill-Eubanks D,Nelson MT

    更新日期：2017-05-01 00:00:00

  • In vivo intracellular recording and perturbation of persistent activity in a neural integrator.

    abstract：:To investigate the mechanisms of persistent neural activity, we obtained in vivo intracellular recordings from neurons in an oculomotor neural integrator of the goldfish during spontaneous saccades and fixations. Persistent changes in firing rate following saccades were associated with step changes in interspike membr...

    journal_title：Nature neuroscience

    pub_type： 杂志文章

    doi：10.1038/84023

    authors： Aksay E,Gamkrelidze G,Seung HS,Baker R,Tank DW

    更新日期：2001-02-01 00:00:00

  • Ultrasonic signals associated with different types of social behavior of mice.

    abstract：:Communication plays an integral role in human social dynamics and is impaired in several neurodevelopmental disorders. Mice are used to study the neurobiology of social behavior; however, the extent to which mouse vocalizations influence social dynamics has remained elusive because it is difficult to identify the voca...

    journal_title：Nature neuroscience

    pub_type： 杂志文章

    doi：10.1038/s41593-020-0584-z

    authors： Sangiamo DT,Warren MR,Neunuebel JP

    更新日期：2020-03-01 00:00:00