Composition bias and genome polarity of RNA viruses.

abstract：:Immunisation of goats, mice, rats, rabbits, guinea pigs, and hamsters with the recombinant ectodomain of the porcine endogenous retrovirus (PERV) transmembrane envelope (TM) protein (p15E) induced binding and neutralising immune antibodies in all animals. In contrast, no antibodies were induced when pigs were immunise...

journal_title：Virus research

authors： Denner J,Petersen B,Niemann H

更新日期：2015-10-02 00:00:00

abstract：:Transmissible spongiform encephalopathies (TSE) are a heterogeneous group of neurodegenerative disorders. The common feature of these diseases is the pathological conversion of the normal cellular prion protein (PrP(C)) into a β-structure-rich conformer-termed PrP(Sc). The latter can induce a self-perpetuating process...

journal_title：Virus research

authors： Le NT,Narkiewicz J,Aulić S,Salzano G,Tran HT,Scaini D,Moda F,Giachin G,Legname G

更新日期：2015-09-02 00:00:00

abstract：:Bovine herpesvirus-1 infected cell protein 27 (BICP27) was detected predominantly in the nucleolus. The open reading frame of BICP27 was fused with the enhanced yellow fluorescent protein (EYFP) gene to investigate its subcellular localization in live cells and BICP27 was able to direct monomeric, dimeric or trimeric ...

journal_title：Virus research

authors： Guo H,Ding Q,Lin F,Pan W,Lin J,Zheng AC

更新日期：2009-11-01 00:00:00

abstract：:The extensive nucleotide sequence heterogeneity among independent genotypes of wild polioviruses permits the systematic design of genotype-specific molecular reagents. We have prepared two sets of polymerase chain reaction (PCR) primer pairs specific for the genotype of wild poliovirus type 3 recently endemic to Mexic...

journal_title：Virus research

authors： Yang CF,De L,Yang SJ,Ruiz Gómez J,Cruz JR,Holloway BP,Pallansch MA,Kew OM

更新日期：1992-08-01 00:00:00

abstract：:Reovirus is a gastroenteric virus with a genome that consists of ten segments of double-stranded RNA. The segmented nature of the genome allows for genetic mixing when cells are simultaneously infected with two different viral serotypes. The ability of viral reassortment to take place in asynchronous infections has no...

journal_title：Virus research

authors： Keirstead ND,Coombs KM

更新日期：1998-04-01 00:00:00

abstract：:Ribosomal frameshifting is a mechanism of gene expression used by several RNA viruses to express replicase enzymes. This article focuses on frameshifting in two human pathogens, the retrovirus human immunodeficiency virus type 1 (HIV-1) and the coronavirus responsible for severe acute respiratory syndrome (SARS). The ...

journal_title：Virus research

authors： Brierley I,Dos Ramos FJ

更新日期：2006-07-01 00:00:00

abstract：:Genome organization and gene expression of Borna disease virus (BDV) are remarkable for the overlap of open reading frames, transcription units and transcription signals, readthrough of transcription termination signals, differential use of translation initiation codons, and exploitation of the cellular splicing machi...

journal_title：Virus research

authors： Siemetzki U,Ashok MS,Briese T,Lipkin WI

更新日期：2009-09-01 00:00:00

abstract：:DNA polymerase (DNApol) is highly conserved in baculovirus and is required for viral DNA replication. However, little is known about gammabaculovirus DNApol. Here DNApol of the gammabaculovirus Neodiprion lecontei nucleopolyhedrovirus (NeleNPV) was cloned into a dnapol-null alphabaculovirus AcMNPV bacmid, creating Bac...

journal_title：Virus research

authors： Chen G,Fang Y,Yan Q,Li P,Wu L,Feng G

更新日期：2019-06-01 00:00:00

abstract：:Viral expression varies widely between untransformed HTLV-1 positive clones derived from infected individuals without malignancy. Here we show that, in the absence of malignancy, 68% of HTLV-1 positive clones carry deleted (10%) or methylated (58%) 5' LTR. These changes were found to contribute to the fluctuation of v...

journal_title：Virus research

authors： Sibon D,Zane L,Idrissi ME,Delfau-Larue MH,Gessain A,Gout O,Mortreux F,Wattel E

更新日期：2013-12-26 00:00:00

abstract：:We have developed a system for the preparation of La Crosse virus (LAC) and Hantaan virus (HTN) pseudotypes using a murine leukemia virus vector. After concentration, the pseudotypes were present in quantities sufficient to analyze cell tropism and neutralization. Cells resistant to LAC could not be infected with the ...

journal_title：Virus research

authors： Ma M,Kersten DB,Kamrud KI,Wool-Lewis RJ,Schmaljohn C,González-Scarano F

更新日期：1999-10-01 00:00:00

abstract：:Equine rhinitis B virus (ERBV) is the single species in the genus Erbovirus, family Picornaviridae. Equine rhinitis B viruses exist in three serotypes and are associated with respiratory disease in horses. Members of the species vary in stability at acid pH. To date there has been discordance in genotype, serotype and...

journal_title：Virus research

authors： Horsington JJ,Gilkerson JR,Hartley CA

更新日期：2011-02-01 00:00:00

abstract：:Certain insect cell lines have been shown to be permissive (TN-368) or semipermissive (IPLB-LD-652Y) for Autographa californica nuclear polyhedrosis virus (AcMNPV) replication (McClintock et al., 1986b). In this report DNA-binding proteins were identified in such cell:virus systems by hybridizing Western blots contain...

journal_title：Virus research

authors： McClintock JT,Guzo D,Guthrie KP,Dougherty EM

更新日期：1991-07-01 00:00:00

abstract：:Friesian calves were infected with one of three isolates of bovine viral diarrhoea virus (BVDV) and used to establish parameters for an in vitro model of BVDV-reactive T-cell responses in cattle. The study assessed virus clearance, seroconversion, maturation of lymphoproliferative responses (both during and following ...

journal_title：Virus research

authors： Collen T,Morrison WI

更新日期：2000-03-01 00:00:00

abstract：:Nearly 100 years after its discovery poliovirus remains one of most thoroughly studied and best understood virus models for the molecular virologist. While poliovirus has been of vital importance for our insight into picornavirus biology at the cellular and biochemical level, it is ironic to note that, due to the earl...

journal_title：Virus research

authors： Mueller S,Wimmer E,Cello J

更新日期：2005-08-01 00:00:00

abstract：:Highly pathogenic avian H5N1 influenza A viruses occasionally infect humans and cause severe respiratory disease and fatalities. Currently, these viruses are not efficiently transmitted from person to person, although limited human-to-human transmission may have occurred. Nevertheless, further adaptation of avian H5N1...

journal_title：Virus research

authors： Imai M,Herfst S,Sorrell EM,Schrauwen EJ,Linster M,De Graaf M,Fouchier RA,Kawaoka Y

更新日期：2013-12-05 00:00:00

abstract：:MicroRNAs (miRNAs) play important roles in viral infections, especially by modulating the expression of cellular factors essential to viral replication or the host innate immune response to infection. To identify host miRNAs important to controlling porcine reproductive and respiratory syndrome virus (PRRSV) infection...

journal_title：Virus research

authors： Li L,Wei Z,Zhou Y,Gao F,Jiang Y,Yu L,Zheng H,Tong W,Yang S,Zheng H,Shan T,Liu F,Xia T,Tong G

更新日期：2015-01-02 00:00:00

abstract：:An account is given of progress during the last 30 years in knowledge of the epidemiology of diseases caused by aphid-borne viruses in seed potato production areas of northern Europe. During this period, Potato leafroll virus (PLRV) and strains of Potato virus Y (PVY(O), PVY(N)) were consistently the most prevalent an...

journal_title：Virus research

authors： Robert Y,Woodford JA,Ducray-Bourdin DG

更新日期：2000-11-01 00:00:00

abstract：:The nucleoprotein (N), phosphoprotein (P) and glycoprotein (G) genes of Irkut and West Caucasian bat viruses (WCBV) were sequenced and compared with those of other lyssaviruses. N gene nucleotide identities provided unequivocal separation of all lyssavirus genotypes with an identity threshold of 82%. On this basis, Ir...

journal_title：Virus research

authors： Kuzmin IV,Hughes GJ,Botvinkin AD,Orciari LA,Rupprecht CE

更新日期：2005-07-01 00:00:00

abstract：:The CRISPR-Cas9 (clustered regularly interspaced short palindromic repeats and CRISPR-associated protein 9) system has been widely used for viral genome editing, transcription regulation and chromosomal localization in eukaryotic cells. In this study, a guide RNA (gRNA) that specifically recognizes HSV-1 viral genomes...

journal_title：Virus research

authors： Li Z,Bi Y,Xiao H,Sun L,Ren Y,Li Y,Chen C,Cun W

更新日期：2018-01-15 00:00:00

abstract：:Human herpesvirus 6 (HHV-6) is now classified into two distinct variants such as HHV-6 variant A(HHV-6A) and B(HHV-6B) (Ablashi et al., Arch. Virol. 129, 1993, 1-4) and the DNA of HHV-6A strain U1102 was completely sequenced (Gompels et al., Virology 209, 1995, 29-51). We have sequenced a 30-kilobase pair (kbp) (genom...

journal_title：Virus research

authors： Kosuge H,Isegawa Y,Yamanishi K

更新日期：1997-11-01 00:00:00

abstract：:At present there is much interest in the cell tropism and host range of influenza viruses, especially those of the H5N1 subtype. We wished to develop a method that would enable investigation of attachment of infectious virus through the interaction of the hemagglutinin molecule and live mammalian and avian cells and t...

journal_title：Virus research

authors： Rimmelzwaan GF,Nieuwkoop NJ,de Mutsert G,Boon AC,Kuiken T,Fouchier RA,Osterhaus AD

更新日期：2007-11-01 00:00:00

abstract：:The putative envelope glycoproteins of hepatitis C virus (HCV), E1 and E2, were expressed as recombinant, secretory proteins in Sf9 insect cells through infection with recombinant baculoviruses. The influenza virus hemagglutinin signal sequence (HASS) was inserted upstream of the HCV-cDNAs in order to effect secretion...

journal_title：Virus research

authors： Hüssy P,Schmid G,Mous J,Jacobsen H

更新日期：1996-11-01 00:00:00

abstract：:The generation of a new panel of 32 monoclonal antibodies (MAbs) reactive with the P protein of the raccoon strain of rabies virus is described. Through a series of analyses employing competitive ELISA and immunoblotting, these MAbs were classified into eight groups, each defining an antigenic site, thereby increasing...

journal_title：Virus research

authors： Nadin-Davis SA,Fehlner-Gardiner C,Sheen M,Wandeler AI

更新日期：2010-09-01 00:00:00

abstract：:Variants assigned to GI-23 lineage of infectious bronchitis virus (IBV), formerly called Var2, have circulated for nearly 20 years only in countries of the Middle East. Strains of this lineage were first identified in Israel in 1998. More severe form of the virus appeared in 2006, when the second wave of Var2 epidemic...

journal_title：Virus research

authors： Lisowska A,Sajewicz-Krukowska J,Fusaro A,Pikula A,Domanska-Blicharz K

更新日期：2017-10-15 00:00:00

abstract：:Epithelial cells are the major in vivo target cells for porcine circovirus type 2 (PCV2). Although these cells are used for most studies of PCV2 gene expression and, little is known on PCV2 entry, attachment and internalization, in epithelial cells. PCV2 attachment to epithelial cells occurred rapidly and in a time-de...

journal_title：Virus research

authors： Misinzo G,Delputte PL,Lefebvre DJ,Nauwynck HJ

更新日期：2009-01-01 00:00:00

abstract：:Infectious spleen and kidney necrosis virus (ISKNV) is a typical species of the genus Megalocytivirus in the family Iridoviridae. However, until recently, no suitable piscine cell line is stably susceptible to ISKNV. Here, a continuous cell culture derived from the mandarin fish fry (MFF-1) was developed and has been ...

journal_title：Virus research

authors： Dong C,Weng S,Shi X,Xu X,Shi N,He J

更新日期：2008-08-01 00:00:00

abstract：:The family Circoviridae comprises a large group of small circular single-stranded DNA viruses with several members causing severe pig and poultry diseases. In recent years the number of new viruses within the family has had an explosive increase showing a high level of genetic diversity and a broad host range. In this...

journal_title：Virus research

authors： Zhu A,Jiang T,Hu T,Mi S,Zhao Z,Zhang F,Feng J,Fan Q,He B,Tu C

更新日期：2018-05-02 00:00:00

abstract：:Blackberry yellow vein disease is the most important viral disease of blackberry in the United States. Experiments were conducted to characterize a new virus identified in symptomatic plants. Molecular analysis revealed a genome organization resembling Grapevine leafroll-associated virus 3, the type species of the gen...

journal_title：Virus research

authors： Thekke-Veetil T,Aboughanem-Sabanadzovic N,Keller KE,Martin RR,Sabanadzovic S,Tzanetakis IE

更新日期：2013-12-26 00:00:00

abstract：:We here report the results of an investigation of the effect of interferon on the establishment of new infections by a retrovirus. For this study, we used an infectious but replication-incompetent retrovirus carrying a drug-resistance gene and assayed for infectivity by measuring drug-resistant colony formation. Mouse...

journal_title：Virus research

authors： Kumar R,Sen GC

更新日期：1989-08-01 00:00:00

abstract：:To identify the parts of retroviral integrase that interact with its DNA substrates, we compared the patterns of target site usage by chimeric enzymes and protein fragments in assays that reveal integrase's non-specific nuclease activities. The central region of 12 chimeric proteins between the human immunodeficiency ...

journal_title：Virus research

authors： Katzman M,Sudol M,Pufnock JS,Zeto S,Skinner LM

更新日期：2000-01-01 00:00:00