Description and quantification of cocaine withdrawal signs in Planaria.

Abstract:

:Previous work provided indirect evidence that planarians undergo abstinence-induced withdrawal from cocaine. The present study's purpose was to determine if planarians display withdrawal signs and, if so, to quantify the behaviors. Planarians were soaked in cocaine then transferred to either the same cocaine concentration or cocaine-free water. Compared to the cocaine/cocaine group, the cocaine/water group displayed a significant number of atypical behaviors, providing direct evidence of a 'withdrawal phenomenon' in planarians.

journal_name

Brain Res

journal_title

Brain research

authors

Raffa RB,Desai P

doi

10.1016/j.brainres.2004.10.052

subject

Has Abstract

pub_date

2005-01-25 00:00:00

pages

200-2

issue

1-2

eissn

0006-8993

issn

1872-6240

pii

S0006-8993(04)01781-0

journal_volume

1032

pub_type

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