Description and quantification of cocaine withdrawal signs in Planaria.

abstract：:The properties of junctions formed de novo in ectopic regions of muscle were studied and compared to those of endplates reinnervated after nerve crush and to normals. The nerve to the frog cutaneous pectoris muscle was transposed and implanted onto an endplate-free (ectopic) region of that muscle, while the endplate-c...

journal_title：Brain research

authors： Ding R

更新日期：1982-12-16 00:00:00

abstract：:Evidence exists that repeated injections of melatonin in rather large doses inhibit sexual performance in male rats. In contrast, systemic injection of small doses of this hormone stimulates sexual activity of normal male rats. In these experiments, systemic acute administration of melatonin in small doses (10-100 mic...

journal_title：Brain research

authors： Drago F,Busa' L

更新日期：2000-09-29 00:00:00

abstract：:Repeated intermittent administration of amphetamines acutely increases appetitive and consummatory aspects of motivated behaviors as well as general activity and exploratory behavior, including voluntary running wheel activity. Subsequently, if the drug is withdrawn, the frequency of these behaviors decreases, which i...

journal_title：Brain research

authors： Kitanaka N,Kitanaka J,Hall FS,Uhl GR,Watabe K,Kubo H,Takahashi H,Tatsuta T,Morita Y,Takemura M

更新日期：2012-01-06 00:00:00

abstract：:Twelve weeks after focal ventrolateral cerebrocortical suction lesions (ca. 12 X 4 mm) were made in rats, concentrations of the monoamines norepinephrine (NE), dopamine (DA), and serotonin (5-HT) and their metabolites were measured in several cortical and subcortical brain regions using high performance liquid chromat...

journal_title：Brain research

authors： Finklestein S,Campbell A,Baldessarini RJ,Moya KL,Haber SN

更新日期：1985-10-07 00:00:00

abstract：:The cellular and intracellular localization of the epsilon-subspecies of protein kinase C (PKC) in the rat brain was demonstrated by immunocytochemistry using specific antibodies against epsilon-PKC. The epsilon-PKC-specific immunoreactivity was most abundant in the hippocampal formation, olfactory tubercle and Callej...

journal_title：Brain research

authors： Saito N,Itouji A,Totani Y,Osawa I,Koide H,Fujisawa N,Ogita K,Tanaka C

更新日期：1993-04-02 00:00:00

abstract：:We have previously described a rodent model of brief (30 min) middle cerebral artery occlusion followed by reperfusion, in which infarction develops gradually, reaching completion more than 3 days after ischemia, accompanied by morphological, biochemical, and pharmacological evidence of apoptosis. In the present study...

journal_title：Brain research

authors： Snider BJ,Du C,Wei L,Choi DW

更新日期：2001-11-02 00:00:00

abstract：:Injection of a potent, cholinergic muscarinic antagonist, [3H]3-quinuclidinyl benzilate ([3H]QNB), results in a localization of the drug to muscarinic receptors in rat brain. The distribution of these drug receptors was examined in various brain regions previously thought to contain cholinergic neurons. They were loca...

journal_title：Brain research

authors： Kuhar M,Yamamura HI

更新日期：1976-07-09 00:00:00

abstract：:Cerebellar Purkinje neurons (PNs) are selectively vulnerable to AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazolepriopionic acid)-induced delayed neurotoxicity known as dark cell degeneration (DCD) that is expressed as cytoplasmic and nuclear condensation, neuron shrinkage, and failure of physiology. The present study ...

journal_title：Brain research

authors： Strahlendorf J,Box C,Attridge J,Diertien J,Finckbone V,Henne WM,Medina MS,Miles R,Oomman S,Schneider M,Singh H,Veliyaparambil M,Strahlendorf H

更新日期：2003-12-24 00:00:00

abstract：:Male ICR mice were fed powdered laboratory chow containing phenobarbital for 7 days to induce tolerance. Mice were sacrificed and brains assayed for changes in GABA-mediated chloride flux into brain membrane vesicles (microsacs). Concentration-dependent stimulation of chloride flux by GABA alone was not affected by th...

journal_title：Brain research

authors： Allan AM,Zhang X,Baier LD

更新日期：1992-08-21 00:00:00

abstract：:In gerbils pentylenetetrazole- or handling-induced seizures were accompanied by cerebral formation of small amounts of cysteinyl-leukotrienes (LT) but large amounts of prostaglandin (PG) F2 alpha. By contrast, in rats injected with pentylenetetrazole or bicuculline very large amounts of PGF2 alpha but no cysteinyl-LT ...

journal_title：Brain research

authors： Simmet T,Tippler B

更新日期：1991-02-01 00:00:00

abstract：:Mammalian neostriatum is composed of two neurochemically and neuroanatomically defined compartments, called the patches and matrix. The present study concerns a search for neurochemical molecules involved in formation of the striatal compartments. Using the monoclonal antibody CR-50, we here disclose a transient expre...

journal_title：Brain research

authors： Nishikawa S,Goto S,Hamasaki T,Ogawa M,Ushio Y

更新日期：1999-12-11 00:00:00

abstract：:Effects of methamphetamine (MAP) on the extracellular neuropeptide Y (NPY) and noradrenaline (NA) levels were examined in the vicinity of the paraventricular nucleus (PVN) of freely moving rats by means of push-pull perfusion. The NA and NPY levels increased significantly in 30-60 min and reached the maximum level in ...

journal_title：Brain research

authors： Yoshihara T,Honma S,Mitome M,Honma K

更新日期：1996-01-22 00:00:00

abstract：:The distribution of hypocretin-1 (hcrt-1) and hypocretin-2 (hcrt-2) immunoreactivities in the cat brainstem was examined using immunohistochemical techniques. Hcrt-1- and hcrt-2-positive fibers with varicosities were detected in almost all brainstem regions. However, no hcrt-1- or hcrt-2-immunoreactive neuronal somata...

journal_title：Brain research

authors： Zhang JH,Sampogna S,Morales FR,Chase MH

更新日期：2004-01-09 00:00:00

abstract：:Rabbits reared from birth in stroboscopic illumination have no experience of visual motion. In primary visual cortex of these animals there is a large reduction in the number of cells which are direction selective. This result, contrary to previous reports, shows that the rabbit visual system can be modified by early ...

journal_title：Brain research

authors： Pearson HE,Berman N,Murphy EH

更新日期：1981-01-01 00:00:00

abstract：:We here review modulation of olfactory guided behavioral tasks by noradrenaline. In this review we focus on modulation of the main olfactory system in adult rodents. We detail behavioral paradigms commonly used and discuss how sensory perception and learning can be measured using these paradigms. We then describe neur...

journal_title：Brain research

authors： Linster C,Escanilla O

更新日期：2019-04-15 00:00:00

abstract：:The motivational effects of exclusively peripheral or central opiate receptor blockade were studied using place conditioning. Place aversions were observed with intraventricular (i.c.v.) methylnaloxone (MN) in both naive (200-1000 ng) and morphine-dependent rats (50-500 ng). Subcutaneous MN (0.03-10 mg/kg) was ineffec...

journal_title：Brain research

authors： Hand TH,Koob GF,Stinus L,Le Moal M

更新日期：1988-12-06 00:00:00

abstract：:The effects of two specific tyrosine kinase inhibitors on long-term potentiation (LTP) in the dentate gyrus were investigated using anesthetized rats. I.c.v. injection of herbimycin A (1.74 nmol) or lavendustin A (1.31 nmol) before application of tetanic stimulation significantly inhibited the formation of LTP. Howeve...

journal_title：Brain research

authors： Abe K,Saito H

更新日期：1993-09-03 00:00:00

abstract：:Numerous studies have suggested that nitric oxide (NO) in the nucleus tractus solitarii (NTS) participates in modulating cardiovascular function. Nitric oxide synthase (NOS), the enzyme responsible for synthesis of NO, exists in 3 isoforms: endothelial NOS (eNOS), neuronal NOS (nNOS), and inducible NOS (iNOS). Althoug...

journal_title：Brain research

authors： Lin LH,Taktakishvili O,Talman WT

更新日期：2007-09-26 00:00:00

abstract：:The L-isomer of beta-N-methylamino-L-alanine (BMAA), present in free form in seed of Cycas circinalis, elicits in spinal cord cultures a pattern of acute postsynaptic neuronal vacuolation comparable to that induced by beta-N-oxalylamino-L-alanine (BOAA), an excitotoxic amino acid of greater potency isolated from seed ...

journal_title：Brain research

authors： Nunn PB,Seelig M,Zagoren JC,Spencer PS

更新日期：1987-05-05 00:00:00

abstract：:Perfusion of hippocampal slices with normoxic medium containing no added sodium resulted in a rapid loss of the CA1 population spike, with only 35 +/- 10% (S.E.M.) (P < 0.001) recovery after a 15 min exposure. This injury was prevented by the non-competitive N-methyl-D-aspartate (NMDA) antagonist MK-801 (93 +/- 4% rec...

journal_title：Brain research

authors： Parsons JE,Wallis RA,Panizzon KL,Wasterlain CG

更新日期：1992-11-06 00:00:00

abstract：:We investigated the brain-stem pathway(s) by which electrical stimulation of the central cut end of the lingual nerve (LN) evokes parasympathetic reflex vasodilatation in the palate contralateral to the stimulated side. This occurs in artificially ventilated, cervically vagosympathectomized cats deeply anesthetized wi...

journal_title：Brain research

authors： Mizuta K,Izumi H

更新日期：2004-09-10 00:00:00

abstract：:Monoclonal antibody N1 reacts by indirect immunofluorescence with the cell surface of tetanus toxin-positive neurons from early postnatal mouse cerebellum. In freshly trypsinized single cell suspensions from early postnatal mouse cerebellum, 5-10% of all viable cells express N1 antigen on their surface. After 3-24 h o...

journal_title：Brain research

authors： Schnitzer J,Kim SU,Schachner M

更新日期：1984-07-01 00:00:00

abstract：:Common marmosets were given a subcutaneous injection of MPTP (1.25-2.5 mg/kg twice a week) for 5 or 10 consecutive months and were sacrificed after a survival time of 6 months or 15 days, respectively. The parkinsonian symptoms were not very marked at the time of sacrifice but there was a strong decrease of dopamine a...

journal_title：Brain research

authors： Pérez-Otaño I,Herrero MT,Oset C,De Ceballos ML,Luquin MR,Obeso JA,Del Río J

更新日期：1991-12-13 00:00:00

abstract：:Morphologically distinct subsets of mesotelencephalic neurons were sought following retrograde transport of Fluoro-Gold from iontophoretic injections relatively restricted to the medial shell, core or rostral pole subterritories of the nucleus accumbens. The diameter and lengths of Fluoro-Gold immunolabeled dendrites ...

journal_title：Brain research

authors： Tan Y,Brog JS,Williams ES,Zahm DS

更新日期：1995-08-14 00:00:00

abstract：:Somatostatin receptors have been identified in different brain areas but the characterization of their postreceptor effect is still lacking. In this study we analyze the somatostatin effect on adenylate cyclase activity in different brain regions, namely frontal cortex, striatum, hypothalamus and hippocampus. Somatost...

journal_title：Brain research

authors： Schettini G,Florio T,Meucci O,Landolfi E,Grimaldi M,Ventra C,Marino A

更新日期：1989-07-17 00:00:00

abstract：:The present study attempts to elucidate the possible role of adenosine 3',5'-monophosphate (cAMP) and prostaglandin E2 (PGE2) in the function of the neural luteinizing hormone-releasing hormone (LH-RH) apparatus. To this end, in vitro LH-RH release from superfused hypothalamic fragments and cAMP production by hypothal...

journal_title：Brain research

authors： Kim K,Ramirez VD

更新日期：1986-10-29 00:00:00

abstract：:Responses of subthalamic neurons (STN) to the iontophoretic application of glutamate (Glu), acetylcholine (ACh) and GABA were studied in rats 2 or 3 weeks following bilateral decortication, and were compared to those obtained in normal animals. All the cells recorded in lesioned rats showed a decrease in their spontan...

journal_title：Brain research

authors： Rouzaire-Dubois B,Scarnati E

更新日期：1987-02-17 00:00:00

abstract：:Noise analysis was used to estimate the single-channel conductance and number of channels responsible for the mechanically-activated current in the sensory neurons of a spider mechanoreceptor organ. External slits of the VS-3 slit-sense organ in the patellar cuticle of Cupiennius salei were moved with a piezoelectric ...

journal_title：Brain research

authors： Höger U,French AS

更新日期：1999-05-01 00:00:00

abstract：:The resurgent Na(+) current (I(NaR)) is a component of neuronal voltage-dependent Na(+) currents that is activated by repolarization and is believed to result from an atypical path of Na(+)-channel recovery from inactivation. So far, I(NaR) has only been identified in a small number of central neuronal populations in ...

journal_title：Brain research

authors： Castelli L,Nigro MJ,Magistretti J

更新日期：2007-08-13 00:00:00

abstract：:We investigated the electrophysiological properties of the area postrema neurons in acutely prepared rat brain slices using the whole-cell patch-clamp technique. Two different types of transient outward potassium current (I(to)), fast and slow, were found in the area postrema. Both the decay time constant and rise tim...

journal_title：Brain research

authors： Funahashi M,Mitoh Y,Matsuo R

更新日期：2002-06-28 00:00:00