Estimated single-channel conductance of mechanically-activated channels in a spider mechanoreceptor.

abstract：:Exposure of newborn rats to antiepileptics such as barbiturates has long-lasting detrimental effects on the hippocampus and hippocampus-dependent behavior. However, the long-term consequences of neonatal administration with barbiturates on the hippocampal synaptic plasticity remain unresolved. In this study, we invest...

journal_title：Brain research

authors： Tachibana K,Hashimoto T,Kato R,Tsuruga K,Ito R,Morimoto Y

更新日期：2011-05-04 00:00:00

abstract：:Alpha-bungarotoxin binding sites in chick retina from 12 days in ovo to hatching, were visualized at the ultrastructural level by use of a 1:1 conjugate of horseradish peroxidase with alpha-bungarotoxin. At all stages binding sites in the inner plexiform layer were localized in synapses, predominantly on or near the p...

journal_title：Brain research

authors： Daniels MP,Vogel Z

更新日期：1980-11-10 00:00:00

abstract：:Sleep deprivation leads to cognitive impairments in humans and, if sustained for 2-3 weeks in rats, it is invariably fatal. It has been suggested that neural activity associated with waking, if it is not interrupted by periods of sleep, may damage brain cells through excitotoxic or oxidative mechanisms and eventually ...

journal_title：Brain research

authors： Cirelli C,Shaw PJ,Rechtschaffen A,Tononi G

更新日期：1999-09-04 00:00:00

abstract：:The actions of pentobarbital (PB) and diphenylhydantoin (DPH) have been studied on neurons of dorsal root ganglia from adult rats. At anesthetic level (i.e. 1--2 x 10(-4) M), PB greatly enhanced neuronal responses to gamma-aminobutyric acid (GABA); at 10(-3) M PB caused a small depolarization and profoundly attenuated...

journal_title：Brain research

authors： Connors BW

更新日期：1981-03-02 00:00:00

abstract：:We have shown previously that plasmin facilitated the generation of long-term potentiation (LTP) in CA1 and dentate region of rat hippocampus. In the present study, we investigated the effects of plasmin on postsynaptic currents in CA1 pyramidal neurons of rat hippocampal slices. Plasmin (100 nM) had no effect on NMDA...

journal_title：Brain research

authors： Mizutani A,Tanaka T,Saito H,Matsuki N

更新日期：1997-06-27 00:00:00

abstract：:Mesencephalic dopamine neurons form synapses with acetylcholine (ACh)-containing interneurons in the nucleus accumbens (NAcc). Although their involvement in drug reward has not been systematically investigated, these large aspiny interneurons may serve an important integrative function. We previously found that repeat...

journal_title：Brain research

authors： Mark GP,Kinney AE,Grubb MC,Zhu X,Finn DA,Mader SL,Berger SP,Bechtholt AJ

更新日期：2006-12-06 00:00:00

abstract：:The effects of exo- and endogenous cGMP on the resting activity (RA) of afferent crista fibers were studied in isolated preparations of the statocysts of the cuttlefish Sepia officinalis and the squid Sepioteuthis lessoniana. Bath application of the membrane-permeable cGMP analogs 8-bromo-cGMP (B-cGMP) and N(2),2'-o-d...

journal_title：Brain research

authors： Tu Y,Budelmann BU

更新日期：2000-10-13 00:00:00

abstract：:In addition to synaptic remodeling, formation of new neurons is increasingly acknowledged as an important cue for plastic changes in the central nervous system. Whereas all vertebrates retain a moderate neuroproliferative capacity, phylogenetically younger mammals become dramatically impaired in this potential during ...

journal_title：Brain research

authors： Alpár A,Künzle H,Gärtner U,Popkova Y,Bauer U,Grosche J,Reichenbach A,Härtig W

更新日期：2010-05-12 00:00:00

abstract：:The mechanisms responsible for the rate of rise (RR) of cumulative depolarization induced by dorsal root stimulus trains were investigated with intracellular recordings from motoneurones of the rat isolated spinal cord. The NMDA receptor antagonists CPP or APV depressed the cumulative depolarization but not its RR whi...

journal_title：Brain research

authors： Baranauskas G,Nistri A

更新日期：1996-11-04 00:00:00

abstract：:The aim of the present study was to develop a model culture system for the study of factors controlling regeneration of axons from injured adult mammalian central nervous system. We show, for the first that retinal ganglion cells (RGC) dissociated from adult rat retina, regrow processes in vitro over long distances un...

journal_title：Brain research

authors： Wigley CB,Berry M

更新日期：1988-07-01 00:00:00

abstract：:Neurons from many brainstem nuclei involved in respiratory control increase their firing rate in response to acidosis in vitro, suggesting that they are central chemoreceptors. This property has been considered to be either unique to neurons involved in respiratory control, or at least very unusual for non-respiratory...

journal_title：Brain research

authors： Wang W,Richerson GB

更新日期：2000-03-31 00:00:00

abstract：:Tinnitus, the perception of a phantom sound, is a common consequence of damage to the auditory periphery. A major goal of tinnitus research is to find the loci of the neural changes that underlie the disorder. Crucial to this endeavor has been the development of an animal behavioral model of tinnitus, so that neural c...

journal_title：Brain research

authors： Baizer JS,Manohar S,Paolone NA,Weinstock N,Salvi RJ

更新日期：2012-11-16 00:00:00

abstract：:The mechanism(s) underlying age-associated diminutions in the rat striatal D2 dopamine receptor (D2-receptor) number was investigated. The levels of D2-receptor mRNA in 4-, 12- and 18-month-old rat striata were found not to change. In contrast, the levels of 110 kDa protein, labeled with a D2-receptor specific antibod...

journal_title：Brain research

authors： Sakata M,Farooqui SM,Prasad C

更新日期：1992-03-20 00:00:00

abstract：:Neuropeptide Y (NPY, 1 and 10 pmol), NPY Y1 receptor agonist [Leu31, Pro34]NPY (10 pmol) and Y2 agonist NPY13-36 (100 pmol) were administered unilaterally into the region of the nucleus locus coeruleus (LC) in rats. NPY (10 pmol) and NPY13-36 increased the percentage of open arm entries, the percentage of time spent o...

journal_title：Brain research

authors： Kask A,Rägo L,Harro J

更新日期：1998-03-30 00:00:00

abstract：:Gaze processing was investigated using event-related potentials in two different tasks in which front-view and 3/4-view faces were presented, with eyes gazing straight ahead or averted. Task alternated between an explicit gaze direction judgment and a judgment on head orientation where gaze was irrelevant. Accuracy an...

journal_title：Brain research

authors： Itier RJ,Alain C,Kovacevic N,McIntosh AR

更新日期：2007-10-26 00:00:00

abstract：:Platelet-derived growth factor-B (PDGF-B) is a growth factor that regulates cell migration, proliferation, and differentiation, and is involved in several physical and pathological processes. The overexpression of PDGF-B in glioma surgical samples revealed its effect on tumorigenesis. In this study, we determined that...

journal_title：Brain research

authors： Zhou Y,Jin G,Mi R,Dong C,Zhang J,Liu F

更新日期：2014-03-27 00:00:00

abstract：:We utilized proton magnetic resonance spectroscopy to evaluate the metabolic profile of the hippocampus and anterior cingulate cortex of the developing rat brain from postnatal days 14-70. Measured metabolite concentrations were modeled using linear, exponential, or logarithmic functions and the time point at which th...

journal_title：Brain research

authors： Ramu J,Konak T,Liachenko S

更新日期：2016-11-15 00:00:00

abstract：:Anterograde and retrograde axonal tracing methods have been combined with transection of the stria terminalis to investigate the centrifugal afferent connections of the accessory olfactory bulb in the mouse. Injection of tritiated proline into the postero-medial cortical amygdaloid nucleus (C3) gives rise to anterogra...

journal_title：Brain research

authors： Barber PC

更新日期：1982-08-12 00:00:00

abstract：:This study examined the projection from the rostral nucleus of the solitary tract (rNST) to the medial parabrachial nucleus (mPBN) in male Wistar rats using DiI as a retrograde tracer and biotinylated dextran as an anterograde tracer. Following successful unilateral injection of DiI into the mPBN (n = 8), retrogradely...

journal_title：Brain research

authors： Williams JB,Murphy DM,Reynolds KE,Welch SJ,King MS

更新日期：1996-10-21 00:00:00

abstract：:Abecarnil is a recently described beta-carboline which acts at central benzodiazepine receptors (BZR) and has anxioselective/anticonvulsant properties. While it may be classified provisionally as a partial agonist at BZR, there is also evidence that its pharmacological profile may be due to a selective action at BZR s...

journal_title：Brain research

authors： Cooper SJ,Greenwood SE

更新日期：1992-12-18 00:00:00

abstract：:Retinal and tectal potentials to alternating gratings were recorded in pigeons raised monocularly deprived. Deprived eyes showed consistent myopia and anterior-posterior axis elongation. In addition, vitreal opacities were observed in 70% of the deprived eyes. In pigeons with vitreal opacities, a reduction of retinal ...

journal_title：Brain research

authors： Bagnoli P,Porciatti V,Francesconi W

更新日期：1985-07-15 00:00:00

abstract：:GABA-A receptors mediate both phasic synaptic inhibition and more recently appreciated tonic currents in the vertebrate central nervous system. We addressed discrepancies in the literature regarding the pharmacology of tonic currents by examining tonic currents in a controlled environment of dissociated, solitary glut...

journal_title：Brain research

authors： Eisenman LN,Kress G,Zorumski CF,Mennerick S

更新日期：2006-11-06 00:00:00

abstract：:The organization of neuronal cell bodies in the caudal preoptic area (POA) and rostral anterior hypothalamic area (AH) was studied in Nissl-stained brain sections from adult male and female ferrets. Computer-assisted image-analysis procedures were developed to help estimate the areas of cellular density and the sizes ...

journal_title：Brain research

authors： Tobet SA,Zahniser DJ,Baum MJ

更新日期：1986-02-05 00:00:00

abstract：:Measurements of extracellular Ca2+ and K+ activities [( Ca2+]o, [K+]o) in the superfused cat carotid body in vitro with triple-barrelled ion-selective electrodes have shown that hypoxia induced a decrease in [Ca2+]o of 0.035 +/- 0.17 mM (mean +/- S.D.; n = 17) and a biphasic change in [K+]o which consisted of an incre...

journal_title：Brain research

authors： Delpiano MA,Acker H

更新日期：1989-03-20 00:00:00

abstract：:Expertise offers a unique insight into how our brain functions. The purpose of this experiment was to determine if motor system activity and functional connectivity between the cognitive system and sensorimotor system is differentially modulated by an individual's level of expertise. This goal was achieved through the...

journal_title：Brain research

authors： Tomasino B,Maieron M,Guatto E,Fabbro F,Rumiati RI

更新日期：2013-12-02 00:00:00

abstract：:Preparations of lysed synaptosomes exhibit a high affinity Ca2+/Mg2+ ATPase and ATP-dependent Ca2+ accumulation activity, with a Km for Ca2+ congruent to 0.5 microM, close to the cytosolic concentration of Ca2+. When these membrane suspensions were incubated with cholinergic agonists muscarine or oxotremorine (1-20 mi...

journal_title：Brain research

authors： Ross DH,Shreeve SM,Hamilton MG

更新日期：1985-03-11 00:00:00

abstract：:Ion-selective microelectrode techniques were used to study extracellular K+ changes associated with penicillin-induced epileptogenesis in the CA3 region of hippocampal slices. Recordings were made in slices taken from rats 9-16 days of age, which have a pronounced capacity to undergo prolonged synchronized afterdischa...

journal_title：Brain research

authors： Swann JW,Smith KL,Brady RJ

更新日期：1986-12-01 00:00:00

abstract：:Extracellular single unit recordings were made from various depths in the left olfactory bulb of ten anaesthetised, freely breathing adult hens (Gallus domesticus) using glass insulated tungsten microelectrodes. The 66 spontaneously active neurons recorded had widely variable firing rates (mean 4.9 spikes/s, range 0.1...

journal_title：Brain research

authors： McKeegan DE

更新日期：2002-03-01 00:00:00

abstract：:Regeneration of severed hypothalamic peptidergic neurosecretory axons into the ventral pia-arachnoid was observed in rats at the light microscopic and fine-structural levels. A temporal increase occurred in the number of neurophysin-positive axons regenerating into the leptomeninges for distances up to 3.3 mm by 40 da...

journal_title：Brain research

authors： Dellmann HD,Lue LF,Bellin SI,Ouassat M

更新日期：1988-05-31 00:00:00

abstract：:A direct, although transient, projection from the sensorimotor cortex to the cerebellum has been described previously in the neonatal kitten. The present report demonstrates that this pathway can be induced to persist into juvenile stages of the cat by partially denervating the deep cerebellar nuclei. Most of the cere...

journal_title：Brain research

authors： Panneton WM

更新日期：1986-11-01 00:00:00