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A genome-wide screen for association in Hungarian multiple sclerosis.

Abstract：

:Although the pathogenesis of multiple sclerosis (MS) is not fully understood, substantial evidence points to the involvement of genetic factors. We report on a genome-wide screen for disease association in the Hungarian population using 5532 microsatellite markers. These markers were typed in DNA pools that consisted of 88 MS patients (cases), and 128 unrelated controls. Based on a stringent selection criterion, we obtained 33 markers suggesting association with the disease.

journal_name

J Neuroimmunol

journal_title

Journal of neuroimmunology

authors

Rajda C,Bencsik K,Seres E,Jonasdottir A,Foltynie T,Sawcer S,Benediktsson K,Fossdal R,Setakis E,Compston A,Vécsei L

doi

10.1016/j.jneuroim.2003.08.017

subject

Has Abstract

pub_date

2003-10-01 00:00:00

pages

84-7

issue

1-2

eissn

0165-5728

issn

1872-8421

pii

S0165572803003163

journal_volume

143

pub_type

杂志文章

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