Mechanisms of changes in the erythroid hemopoietic stem during hypoxias of different severity.

Abstract:

:Brain pathology (acute hypoxia and posthypoxic encephalopathy) is associated with less pronounced hyperplasia of the bone marrow erythroid stem (due to decreased count of proliferating committed precursors) and hemolytic anemia, while secretory activity of stromal cells of the hemopoiesis-inducing microenvironment is not impaired. Severe oxygen deficiency affects erythroid precursors and impairs production of functionally normal erythrocytes in the posthypoxic period.

journal_name

Bull Exp Biol Med

authors

Gol'dberg ED,Dygai AM,Zyuz'kov GN,Gur'yantseva LA,Suslov NI

doi

10.1023/a:1021167710993

subject

Has Abstract

pub_date

2002-08-01 00:00:00

pages

122-5

issue

2

eissn

0007-4888

issn

1573-8221

journal_volume

134

pub_type

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