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A genetic basis for obsessive grooming.

Abstract：

:Excessive grooming behaviors, cleansing rituals, and self-mutilation are important features of a range of neuropsychiatric diseases including obsessive compulsive (OC)-spectrum disorders. In this issue of Neuron, Greer and Capecchi (2002) report that Hoxb8 mutant mice exhibit this behavioral phenotype. These Hoxb8 mutants will be valuable in exploring the genetics and pathophysiology of OC-spectrum disorders as well as strategies for their treatment.

journal_name

Neuron

journal_title

Neuron

authors

Graybiel AM,Saka E

doi

10.1016/s0896-6273(01)00575-x

subject

Has Abstract

pub_date

2002-01-03 00:00:00

pages

1-2

issue

1

eissn

0896-6273

issn

1097-4199

pii

S089662730100575X

journal_volume

33

pub_type

评论,杂志文章,评审

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