Focal adhesions: structure and dynamics.

Abstract:

:Interactions of cells with the extracellular matrix are essential for the control of tissue remodelling, cell migration, and embryogenesis. At the cell-extracellular matrix contact points, specialized structures are formed and termed focal adhesions, where transmembrane adhesion receptors provide a structural link between the actin cytoskeleton and the extracellular matrix components. Numerous structural and regulatory proteins assemble at the cytoplasmic face of focal adhesions in a Rho-dependent fashion.

journal_name

Biol Cell

journal_title

Biology of the cell

authors

Petit V,Thiery JP

doi

10.1016/s0248-4900(00)01101-1

subject

Has Abstract

pub_date

2000-10-01 00:00:00

pages

477-94

issue

7

eissn

0248-4900

issn

1768-322X

pii

S0248-4900(00)01101-1

journal_volume

92

pub_type

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