Control of CREB phosphorylation and its role for induction of melatonin synthesis in rat pinealocytes.

abstract：BACKGROUND INFORMATION:The role of the LIM-domain-containing protein Ajuba was initially described in cell adhesion and migration processes and recently in mitosis as an activator of the Aurora A kinase. RESULTS:In the present study, we show that Ajuba localizes to centrosomes and kinetochores during mitosis. This loc...

journal_title：Biology of the cell

authors： Ferrand A,Chevrier V,Chauvin JP,Birnbaum D

更新日期：2009-04-01 00:00:00

abstract：:We studied formation of domes in cell monolayers of the human colon carcinoma cell line Caco-2 which has been shown to exhibit signs of enterocytic differentiation and transport properties. After a 24 hr incubation with 4 X 10(-8) M ouabain, the number of domes seen on Caco-2 cell monolayers grown on plastic dishes wa...

journal_title：Biology of the cell

authors： Ramond MJ,Martinot-Peignoux M,Erlinger S

更新日期：1985-01-01 00:00:00

abstract：:Tensins are focal adhesion molecules that were identified and characterised in the late 1980s to early 1990s. They play an essential role in the control of cell adhesion. Tensins can bind the tail of ß integrin via their phospho tyrosine binding domain, they exhibit various protein interaction domains including a Src ...

journal_title：Biology of the cell

authors： Blangy A

更新日期：2017-03-01 00:00:00

abstract：:Since almost two decades, it is known that progesterone is responsible of the release of the prophase I arrest of amphibian oocytes and leads to the activation of the universal MPF, through a puzzling transduction pathway. It involves negative regulation of the cAMP-dependent protein kinase (PKA) and synthesis of new ...

journal_title：Biology of the cell

authors： Karaiskou A,Dupré A,Haccard O,Jessus C

更新日期：2001-09-01 00:00:00

abstract：:The highly conserved VICKZ (Vg1 RBP/Vera, IMP-1,2,3, CRD-BP, KOC, ZBP-1) family of RNA-binding proteins recognize specific cis-acting elements in a variety of different RNAs and have been implicated in cell polarity and migration, cell proliferation, and cancer. In just the last two years, the use of transgenic mice, ...

journal_title：Biology of the cell

authors： Yisraeli JK

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND INFORMATION:In a previous study, we demonstrated that human neutrophils can develop membrane tubulovesicular extensions (TVEs) that are 160-250 nm in width and several micrometres long. These extensions, or cytonemes, are capable of establishing long-range contacts with other cells or bacteria. Cytonemes con...

journal_title：Biology of the cell

authors： Galkina SI,Fedorova NV,Serebryakova MV,Arifulin EA,Stadnichuk VI,Gaponova TV,Baratova LA,Sud'ina GF

更新日期：2015-05-01 00:00:00

abstract：:Isolated cells from the proximal tubule have previously been used to study specific renal physiological processes. Here we analysed the structural changes induced by mechanical isolation on rat proximal tubule cells. As major modifications we detected: 1) a redistribution of brush border microvilli, which spread out o...

journal_title：Biology of the cell

authors： Rebelo L,Carmo-Fonseca M,Moura TF

更新日期：1992-01-01 00:00:00

abstract：:Oocyte maturation and early development have been intensively studied for well over 100 years. The earliest theory proposed that after fertilisation and during cell division determinants were unequally distributed to control cell fate; experimental proof came from using frog eggs (Roux, 1888). After understanding the ...

journal_title：Biology of the cell

authors： Prigent C,Hunt T

更新日期：2004-04-01 00:00:00

abstract：:Structured mRNA elements called riboswitches control gene expression by binding to small metabolites. Over a dozen riboswitch classes have been characterized that target a broad range of molecules and vary widely in size and secondary structure. Four of the known riboswitch classes recognize purines or modified purine...

journal_title：Biology of the cell

authors： Kim JN,Breaker RR

更新日期：2008-01-01 00:00:00

abstract：:Cell polarity is a fundamental property of cells from unicellular to multicellular organisms. Most of the time, it is essential so that the cells can achieve their function. The fission yeast Schizosaccharomyces pombe is a powerful genetic model organism for studying the molecular mechanisms of the cell polarity proce...

journal_title：Biology of the cell

authors： La Carbona S,Le Goff C,Le Goff X

更新日期：2006-11-01 00:00:00

abstract：:Effect of estradiol-17 beta on rat vaginal epithelial cells (VEC) was studied by transmission electron microscopy. During the normal estrous cycle in adult rats keratinization and exfoliation of VEC was observed only in the estrus phase, though tonofilament bundles were seen distributed in the cytoplasm of the VEC dur...

journal_title：Biology of the cell

authors： Gupta PD,Vijayasaradhi S,Reddy AG

更新日期：1989-01-01 00:00:00

abstract：:Human pancreatic ductal cells of the Capan 1 cell line differentiate progressively during growth. After the exponential growth phase, the cells elongate and become polarized with their apical poles covered by microvilli and separated from the basolateral pole by tight junctions. In this stationary phase, they form dom...

journal_title：Biology of the cell

authors： Mahieu I,Becq F,Wolfensberger T,Gola M,Carter N,Hollande E

更新日期：1994-01-01 00:00:00

abstract：:The interaction of cells with extracellular matrix components contributes to their specific differentiation. We studied hepatic peroxisomes and their changing features during embryonic development, and we immunolocalized in the same tissue the extracellular matrix components laminin and collagen IV as well as the inte...

journal_title：Biology of the cell

authors： Depreter M,Nardacci R,Tytgat T,Espeel M,Stefanini S,Roels F

更新日期：1998-12-01 00:00:00

abstract：BACKGROUND INFORMATION:Homotypic internalisation of tumour cells has frequently been observed in tumour tissue sections. Events of non-professional phagocytosis, however, may also occur in normal tissue if the number of dying cells exceeds the phagocytic capacity of professional phagocytes such as macrophages and dendr...

journal_title：Biology of the cell

authors： Schwegler M,Wirsing AM,Dollinger AJ,Abendroth B,Putz F,Fietkau R,Distel LV

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND INFORMATION:The costa is a prominent striated fibre that is found in protozoa of the Trichomonadidae family that present an undulating membrane. It is composed primarily of proteins that have not yet been explored. In this study, we used cell fractionation to obtain a highly enriched costa fraction whose str...

journal_title：Biology of the cell

authors： de Andrade Rosa I,Caruso MB,de Oliveira Santos E,Gonzaga L,Zingali RB,de Vasconcelos ATR,de Souza W,Benchimol M

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND INFORMATION:Continued advances in stem cell biology and stem cell transplantation rely on non-invasive biomarkers to characterise cells and stem cell aggregates. The non-invasive quality of such biomarkers is essential because exogenous labels, probes or reporters can unintentionally and dramatically alter s...

journal_title：Biology of the cell

authors： Buschke DG,Squirrell JM,Fong JJ,Eliceiri KW,Ogle BM

更新日期：2012-06-01 00:00:00

abstract：:The centrosome of the slime mould Dictyostelium discoideum displays a morphology markedly different from centriolar centrosomes or yeast spindle pole bodies, while fulfilling the same conserved functions in the organization of the microtubule cytoskeleton. Recent advances suggest that the Dictyostelium centrosome may ...

journal_title：Biology of the cell

authors： Daunderer C,Schliwa M,Gräf R

更新日期：1999-05-01 00:00:00

abstract：:Evidence is presented that two circumferential zones of cell envelope differentiation, the periseptal annuli, exist in E. coli as previously observed in S. typhimurium. The periseptal annulus is located at the division site of cells. A strain overproducing a periplasmic protein, PhoS (phosphate-binding protein) has be...

journal_title：Biology of the cell

authors： Anba J,Bernadac A,Pages JM,Lazdunski C

更新日期：1984-01-01 00:00:00

abstract：:Multidrug-resistant (MDR) variants of a human osteosarcoma cell line (U-2 OS) have been recently obtained by continuous exposure to doxorubicin (DX). The growth and phenotypic characteristics of these cell lines have been demonstrated to be related to the level of expression of P-glycoprotein. In this work, the morpho...

journal_title：Biology of the cell

authors： Zini N,Scotlandi K,Baldini N,Nini G,Sabatelli P,Maraldi N

更新日期：1995-01-01 00:00:00

abstract：:The isolation, characterization, and expression of a novel cDNA encoding a Trypanosoma cruzi polypeptide (TcAc2), homologous to various small stress proteins and glutathione S-transferases, are described. The deduced amino-acid sequence revealed two domains sharing 27% identity and an additional 27% similarity to each...

journal_title：Biology of the cell

authors： Schöneck R,Plumas-Marty B,Taibi A,Billaut-Mulot O,Loyens M,Gras-Masse H,Capron A,Ouaissi A

更新日期：1994-01-01 00:00:00

abstract：:Previous experiments have revealed a relatively weak electrostatic binding capacity of in vitro reconstituted intermediate filaments (IFs) as well as of natural IFs of whole cell mount preparations for purified ribosomal particles of mammalian origin. In order to demonstrate that such associations also occur in vivo, ...

journal_title：Biology of the cell

authors： Traub P,Bauer C,Hartig R,Grüb S,Stahl J

更新日期：1998-07-01 00:00:00

abstract：:We studied the behaviour in interphase and mitotic human cells of a 125 kDa (pI 6.5) antigen, associated with the nuclear matrix and detected in proliferating cells. Indirect immunofluorescence with a specific monoclonal antibody reveals that during interphase in WISH and Namalwa cells, as well as phytohaemagglutinin-...

journal_title：Biology of the cell

authors： Todorov IT,Philipova PN,Zhelev NZ,Hadjiolov AA

更新日期：1988-01-01 00:00:00

abstract：:Extensive developmentally programmed DNA rearrangements, including thousands of internal deletions, occur in the differentiating somatic macronucleus in Tetrahymena thermophila. Some deletion systems involve the use of multiple alternative deletion sites. We report here the cloning and the sequences of three new alter...

journal_title：Biology of the cell

authors： Chau MF,Orias E

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND INFORMATION:The identification of a source of stem cells able to regenerate skeletal muscle was the goal of numerous studies with the aim to develop new therapeutic approaches for genetic muscle diseases or muscle injuries. A series of studies have demonstrated that stem cells derived from various tissues ma...

journal_title：Biology of the cell

authors： Dimicoli-Salazar S,Bulle F,Yacia A,Massé JM,Fichelson S,Vigon I

更新日期：2011-11-01 00:00:00

abstract：:We have recently shown that staurosporine (ST) can trigger apoptosis of CaSki and HeLa cervical tumor cells from G2/M checkpoint, though the mechanism remains elusive. In this study, we reported that ST induced the inhibition of E6 and E7 viral oncogene and MDM2 expression, while it led to increased levels of p53, whi...

journal_title：Biology of the cell

authors： Bernard B,Prétet JL,Charlot JF,Mougin C

更新日期：2003-01-01 00:00:00

abstract：:We used a high-resolution STEM to attempt to recognize the spatial localization of the macromolecular components of ribosomes isolated from Tetrahymena pyriformis. Images obtained either by the annular dark field detector or by the ratio-contrast mode (Z-contrast) show a ribosome as constituted of rounded dark areas, ...

journal_title：Biology of the cell

authors： Curgy JJ,Iftode F,Perasso R,André J,Mory C,Colliex C

更新日期：1984-01-01 00:00:00

abstract：BACKGROUND INFORMATION:Death receptors (DRs) induce intracellular signalling upon engagement of their cognate ligands, leading to apoptosis, cell survival or pro-inflammatory responses. In mammals, DR signalling is mediated by the recruitment of several DD (death domain)-containing molecules, such as FADD (Fas-associat...

journal_title：Biology of the cell

authors： Ishizawa YH,Tamura K,Yamaguchi T,Matsumoto K,Komiyama M,Takamatsu N,Shiba T,Ito M

更新日期：2006-08-01 00:00:00

abstract：:Flow DNA analysis was performed on samples from 71 surgically removed lung cancers and from 145 patients undergoing bronchoscopy. Abnormal DNA stem lines, characterized by their DNA index (DI), were frequently observed in operated lung carcinomas (87%). Two or three abnormal DNA stem lines were discovered simultaneous...

journal_title：Biology of the cell

authors： Chassevent A,Berruchon J,Bertrand G,Chretien MF,Tuchais C,George P,Larra F,Rebel A,Oury M

更新日期：1986-01-01 00:00:00

abstract：:The development of a single, very large (25-35 microns diameter) nucleolus during oogenesis in the crustacean Acanthocyclops vernalis is described. The nucleolus is the site of ribosomal RNA production in the egg, as shown by in situ hybridization, and apparently the only source, as accessory cells are not observed. R...

journal_title：Biology of the cell

authors： Standiford DM

更新日期：1988-01-01 00:00:00

abstract：BACKGROUND INFORMATION:The mitogen-inducible gene-6 (Mig-6) is a non-kinase scaffolding adaptor protein. It has been shown that Mig-6 may play important roles in regulating stress response, maintaining homeostasis and functioning as a tumour suppressor. In this study, we investigated the role of Mig-6 in cellular senes...

journal_title：Biology of the cell

authors： Xie B,Zhao L,Chen H,Jin B,Mao Z,Yao Z

更新日期：2013-10-01 00:00:00